Virtual Patient Biomarker Analysis for Confidential Clinical Trials

The patent creates virtual patient data that copies the statistical characteristics and patterns of real clinical trial data without using actual patient information. Virtual patients are generated with synthetic survival data, medical images, and clinical parameters that replicate the distribution and relationships found in real data, enabling biomarker analysis while maintaining complete patient privacy and data confidentiality.

The patent introduces virtual patient data as an intermediary between real clinical trial data and biomarker analysis. Instead of directly analyzing sensitive real patient data, the system uses virtual data as a mediator that preserves the statistical properties needed for analysis while eliminating all identifiable patient information, thus resolving the conflict between analysis reliability and data confidentiality.

The patent performs preliminary actions by generating comprehensive virtual patient data sets before conducting biomarker analysis. The system pre-generates virtual patients with complete clinical parameters, medical images, survival outcomes, and treatment responses, ensuring sufficient data quantity is available for robust statistical analysis while maintaining data confidentiality from the outset.

The virtual data generation process creates synthetic patient records that copy the volume, structure, and statistical properties of real clinical trial data. By replicating the data quantity and diversity characteristics of original studies, the system ensures that virtual data provides sufficient statistical power for biomarker analysis without requiring access to actual patient information.