Antioxidant Composition for Skin Rejuvenation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current treatments for cutaneous signs of aging, such as wrinkles and skin thinning, are inadequate in promoting rapid recovery of G1-arrested cells and maintaining skin health, particularly due to the limitations of existing antioxidant combinations in addressing oxidative stress and DNA damage caused by UV radiation.

Innovation Solution

A composition comprising vitamin E, vitamin C, and white tea extract, which acts as an oral nutraceutical supplement, is used to enhance the release of G1-arrested cells into the S phase, promoting skin rejuvenation by inhibiting collagen and elastase enzymes and binding collagen fibers, thereby reducing wrinkles and improving skin elasticity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional antioxidant treatments are used, then skin protection is provided, but rapid recovery of G1-arrested cells is not achieved

Engineering Contradiction:
Improveskin protectionVSAvoidcell recovery rate
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent combines three antioxidants (vitamin E, vitamin C, and white tea extract) into a single composition to achieve synergistic effects. This merging of multiple antioxidant agents provides both reliable skin protection and accelerates G1-arrested cell recovery, resolving the contradiction between protection reliability and cell recovery productivity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention uses a composite antioxidant system comprising vitamin E, vitamin C, and white tea extract. This composite material approach creates a multi-functional formulation that simultaneously provides protective effects and stimulates rapid cell cycle progression, addressing both the reliability and productivity requirements.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If UV radiation protection is provided, then skin damage is reduced, but DNA damage and oxidative stress persist

Engineering Contradiction:
ImproveUV radiation damageVSAvoidoxidative stress
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent converts the harmful effects of UV radiation-induced oxidative stress into a beneficial response by using antioxidant compounds that not only protect against UV damage but also actively reduce existing oxidative stress and DNA damage. The composition transforms the harmful oxidative environment into a controlled therapeutic effect that promotes cell recovery.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The antioxidant composition provides preliminary protection against UV radiation damage while simultaneously counteracting oxidative stress and DNA damage. By applying this multi-component formulation, the skin receives preemptive protection and active remediation before further damage can occur, addressing both external and internal harmful factors.

Inventive Principle:
Principle #9Preliminary anti-action

3Strength

If collagen synthesis is promoted, then skin elasticity improves, but wrinkle reduction is insufficient

Engineering Contradiction:
Improveskin elasticityVSAvoidwrinkle depth
Core Design Contradiction:
StrengthVSShape

Solution Approach 1:

The patent merges collagen synthesis promotion with wrinkle reduction through the combined action of vitamin E, vitamin C, and white tea extract. This synergistic combination simultaneously enhances collagen production and directly addresses wrinkle formation, achieving both improved skin elasticity and visible wrinkle reduction that single agents cannot accomplish alone.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination of vitamin E, vitamin C, and white tea extract effectively accelerates the release of G1-arrested cells, improves skin elasticity, and reduces wrinkles by enhancing collagen synthesis and skin density, demonstrating significant improvements in skin health and appearance.

Implementation Method 1

Vitamin E is an antioxidant; vitamin C (ascorbic acid) assists in the prevention of skin bruising and wound healing

Methodology Applied
Scientific EffectAntioxidant activity: Oxidation

Implementation Method 2

The free radical theory of aging... postulates that the free radical reaction is a single common process that might be responsible for aging

Methodology Applied
Scientific EffectFree radical scavenging: Redox Reactions

Implementation Method 3

enhancing the release of G1-arrested cells, whereby cells recover more rapidly

Methodology Applied
Scientific EffectCell cycle regulation:

Implementation Method 4

inhibiting collagen and elastase enzymes

Methodology Applied
Scientific EffectEnzyme inhibition: Enzyme

Implementation Method 5

binding collagen fibers, thereby reducing wrinkles and improving skin elasticity

Methodology Applied
Scientific EffectCollagen binding: Chemical Bonding

Data Source

PatentUS11039999B2Compositions suitable for treating cutaneous signs of aging
Publication Date: 2021.06.22 AS FERROSAN
  • US11039999B2 patent drawing
  • US11039999B2 patent drawing
  • US11039999B2 patent drawing

AI summary

Compositions comprising vitamin E, vitamin C, and white tea extract for treating cutaneous signs of aging are disclosed. The compositions reduce signs of wrinkles and improve other skin conditions, such as increased skin elasticity and skin softness. Moreover, the prevention or treatment of unhealthy skin, such as aged skin or skin overexposed to sunlight, may advantageously be accomplished by the administration of the compositions of the present invention The compositions includes the combination of a number of different components, which interact to provide the desired improvements to the skin Further advantageous ingredients of the compositions may comprise, naturally occurring antioxidants extracted from e g grape seeds and tomato, an extract comprising glycosaminoglycans, a transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin, and a catechin-based component present in an amount sufficient to inhibit the presence of anti-collagen enzyme in the skin.