Water-Soluble Vitamin E Derivatives for Beverage Solubility
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Solution Overview
Problem
Existing food and beverage products face challenges in incorporating high amounts of non-polar compounds due to poor water solubility, leading to limited concentrations and undesirable organoleptic properties.
Innovation Solution
Development of high dimer-containing water-soluble vitamin E derivative compositions that include a mixture of dimer and monomer forms of vitamin E derivatives, such as TPGS, to enhance the solubility and stability of non-polar compounds like polyunsaturated fatty acids and coenzyme Q10, allowing for higher concentrations in beverages without compromising clarity and taste.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If non-polar compounds are incorporated into aqueous solutions, then the concentration of non-polar compounds is limited, but the solubility and stability of non-polar compounds improve
Solution Approach 1:
The patent uses water-soluble vitamin E derivatives (TPGS) as intermediary substances that act as surfactants to solubilize non-polar compounds in aqueous solutions. The vitamin E derivative forms micellar structures that encapsulate non-polar compounds, enabling their dissolution in water while maintaining stability and allowing higher concentrations without compromising organoleptic properties.
2Quantity of substance
If high amounts of non-polar compounds are added to beverages, then the concentration increases, but the clarity and taste deteriorate
Solution Approach 1:
The water-soluble vitamin E derivative serves as a mediating agent that allows high concentrations of non-polar compounds to be incorporated into beverages without causing turbidity or affecting taste. The derivative forms clear micellar dispersions that maintain beverage clarity while solubilizing large amounts of non-polar ingredients.
Solution Approach 2:
The patent changes the chemical parameter of the vitamin E compound by creating water-soluble derivatives (such as tocopheryl polyethylene glycol succinate) that have different solubility characteristics compared to traditional vitamin E. This parameter change enables the formulation of clear, stable beverages with high non-polar compound content.
3Device complexity
If traditional vitamin E formulations are used, then the formulation is simple, but the solubility of non-polar compounds in water is poor
Solution Approach 1:
The patent modifies the chemical structure parameter of vitamin E by synthesizing water-soluble derivatives with polyethylene glycol chains, transforming it from a lipid-soluble compound to a water-soluble surfactant. This parameter change enables effective solubilization of non-polar compounds in aqueous beverages while maintaining formulation simplicity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The high dimer vitamin E derivative compositions enable the formulation of beverages with increased clarity and stability, allowing for higher concentrations of non-polar compounds while maintaining desirable organoleptic properties, thereby overcoming the limitations of traditional products.
Implementation Method 1
water-soluble vitamin E derivative compositions that include a mixture of dimer and monomer forms of vitamin E derivatives, such as TPGS, to enhance the solubility and stability of non-polar compounds
Data Source
AI summary
Provided are compositions that contain water-soluble vitamin E derivative mixtures (compositions), such as tocopheryl polyethylene glycol succinate (TPGS), TPGS analogs, TPGS homologs and TPGS derivatives. The water-soluble vitamin E mixtures contain mixtures that include dimers and monomers of the vitamin E derivative, where the amount of dimer is greater than 12%, such as 29%, 35%, 50%, 60%, and the amount of monomer is less than 87%, by weight, of the water-soluble vitamin E derivative mixture. Also provided are products containing the water-soluble vitamin E derivative mixtures, including concentrates for dilution into aqueous beverages and compositions for direct ingestion.