Analyte Measurement Using Void-Arranged Structure Scattering

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Solution Overview

Problem

Current methods for measuring analyte properties using electromagnetic waves struggle with low sensitivity, particularly for small quantities, requiring large and complex measuring apparatuses due to the reliance on transmittance spectrum analysis and the difficulty in detecting small changes in dip waveforms.

Innovation Solution

A method involving the application of electromagnetic waves to a void-arranged structure holding the analyte, detecting the scattered electromagnetic waves, and analyzing the ratio or width of specific frequency characteristics to improve sensitivity and enable measurement of smaller analyte quantities, utilizing structures that cause pseudo-TE11 or reduce pseudo-TE10 mode resonance phenomena.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If transmittance spectrum analysis is used to measure analyte properties, then measurement capability is provided, but measuring sensitivity is low and detection of small analyte quantities is difficult

Engineering Contradiction:
Improvemeasuring sensitivityVSAvoidapparatus complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The invention changes the measurement parameter from transmittance spectrum analysis to scattered spectrum analysis. Specifically, it measures the intensity ratio of scattered electromagnetic waves at different frequencies (e.g., f1 and f2) rather than analyzing the entire transmittance spectrum. This parameter change enables detection of small analyte quantities (not more than about 100 ng/mm2) with high sensitivity while using a simpler apparatus that does not require complex spectrometers or frequency acquisition mechanisms.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If dip waveform shifting is used to determine analyte quantity, then analyte detection is possible, but the method fails for small quantities where shifting becomes smaller than detection limit

Engineering Contradiction:
Improvedetection capabilityVSAvoiddetection limit
Core Design Contradiction:
Measurement precisionVSDifficulty of detecting and measuring

Solution Approach 1:

Instead of measuring the frequency shift of dip waveforms (which becomes undetectable for small analyte quantities), the invention changes to measuring the intensity ratio of scattered electromagnetic waves at specific frequencies. This new parameter provides sufficient signal strength even for analyte quantities not more than about 100 ng/mm2, overcoming the detection limit problem inherent in dip waveform shifting methods.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention utilizes resonance phenomena (pseudo-TE11 mode resonance or reduction of pseudo-TE10 mode resonance) in the void-arranged structure to enhance the scattering signal. By operating at frequencies that excite these resonance modes, the scattered wave intensity is amplified, enabling detection of very small analyte quantities that would otherwise produce signals below the detection threshold.

Inventive Principle:
Principle #18Mechanical vibration

3Loss of information

If frequency acquisition mechanism is implemented, then frequency information is obtained, but measuring apparatus becomes large-sized and hard to control

Engineering Contradiction:
Improvefrequency informationVSAvoidapparatus size and controllability
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The invention extracts only the essential information needed for analyte detection—the intensity ratio of scattered waves at two specific frequencies—rather than acquiring the complete frequency spectrum. This extraction approach eliminates the need for complex spectrometers and frequency acquisition mechanisms, resulting in a compact, easily controllable apparatus that still provides sufficient information for accurate analyte measurement.

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances measuring sensitivity, allowing for the detection of smaller analyte quantities without the need for complex apparatuses by focusing on changes in the ratio or width of specific frequency characteristics, thereby improving measurement accuracy and simplifying the measurement process.

Implementation Method 1

detecting the electromagnetic wave scattered by the void-arranged structure holding the analyte

Methodology Applied
Scientific EffectElectromagnetic scattering: Scattering

Implementation Method 2

utilizing structures that cause pseudo-TE11 or reduce pseudo-TE10 mode resonance phenomena

Methodology Applied
Scientific EffectResonance: Resonance

Data Source

PatentUS9007578B2Method for measurement of properties of analyte
Publication Date: 2015.04.14 MURATA MFG CO LTD
  • US9007578B2 patent drawing
  • US9007578B2 patent drawing
  • US9007578B2 patent drawing

AI summary

A measurement method that includes irradiating a void-arranged structure on which an analyte has been held with an electromagnetic wave, detecting an electromagnetic wave scattered on the void-arranged structure, and determining a property of the analyte on the basis of at least one parameter, the parameter including the amount of change in the ratio of the detected electromagnetic wave to the irradiated electromagnetic wave at a specific frequency between the presence and the absence of the analyte.