Volumetric LAT Mapping With Intramural Tissue Interpolation
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Solution Overview
Problem
Conventional methods of constructing local activation time (LAT) maps for heart tissue surfaces in isolation provide inaccurate interpolated values due to the correlation of electrophysiological properties between the endocardial and epicardial surfaces, neglecting the intramural tissue.
Innovation Solution
A volumetric, three-dimensional LAT map is constructed by integrating LAT values from both the endocardial and epicardial surfaces, with interpolated values for intramural voxels using iterative averaging techniques, such as Laplace interpolation, to create a more accurate representation of electrical propagation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional methods construct LAT maps for heart tissue surfaces in isolation, then the mapping process is simple, but the interpolated values are inaccurate due to neglecting intramural tissue
Solution Approach 1:
The patent transitions from conventional two-dimensional surface mapping to three-dimensional volumetric mapping by incorporating intramural tissue between the endocardial and epicardial surfaces. This dimensional expansion allows interpolation of LAT values throughout the full thickness of the myocardium, not just on surfaces, thereby improving measurement accuracy while accepting increased system complexity
Solution Approach 2:
The patent combines LAT data from both endocardial and epicardial surfaces with intramural tissue measurements to create an integrated volumetric map. By merging these previously separate surface-isolated mappings into a unified three-dimensional representation, the system achieves more accurate interpolated values that reflect the true electrophysiological properties throughout the myocardial wall
2Measurement precision
If volumetric LAT map construction is implemented, then accuracy of intramural tissue representation is improved, but computational requirements increase
Solution Approach 1:
The patent performs preliminary actions by first acquiring LAT values from both endocardial and epicardial surfaces before proceeding to volumetric interpolation of intramural tissue. This staged approach allows the system to prepare surface data in advance, which then serves as boundary conditions for the subsequent intramural interpolation, reducing peak computational demands while maintaining accuracy
Data Source
AI summary
A method includes assigning, to first voxels in a model of tissue of a chamber of a heart, respective first values of a parameter at respective locations on the tissue, the first voxels representing the locations, respectively. Some of the locations are on an endocardial surface of the tissue, and others of the locations are on an epicardial surface of the tissue. The method further includes assigning respective second values to second voxels in the model, a subset of which represent a portion of the tissue between the endocardial surface and the epicardial surface, by interpolating the first values. Other embodiments are also described.