Wash Ring Assembly for Probe Washing and Drying
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Solution Overview
Problem
Automated assay devices face challenges in thoroughly washing probes to prevent carryover and cross-contamination between samples, which can lead to inaccurate results and increased processing time due to the need for extensive probe movement during the wash cycle.
Innovation Solution
A wash ring assembly with a cylindrical bore and opposing inlet and outlet openings, capable of moving parallel to the probe's longitudinal axis, is integrated with a robotic probe assembly to efficiently wash and dry the probe's exterior and interior, utilizing a coupling mechanism with a bearing, lead screw, and motor for precise motion control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If the probe travels a longer distance during the wash cycle to ensure thorough cleaning, then the washing effectiveness is improved, but the processing time increases
Solution Approach 1:
The washing process is segmented into multiple zones within the wash ring (entry zone, washing zone, exit zone), allowing thorough cleaning to occur in a compact space rather than requiring long probe travel. The wash ring is divided into functional sections that perform different washing operations sequentially as the probe passes through.
Solution Approach 2:
The invention transitions from linear probe travel for washing to radial/axial washing within a compact ring structure. Wash fluid is delivered through the wall of the wash ring in a direction perpendicular to the probe axis, creating a three-dimensional washing pattern that achieves thorough cleaning without requiring the probe to travel a long distance.
2Measurement precision
If the probe is thoroughly washed to prevent carryover and cross-contamination, then result accuracy is improved, but the device complexity increases
Solution Approach 1:
The wash ring assembly serves multiple functions: it washes the exterior of the probe, cleans the probe tip, and can accommodate different probe sizes through adjustable positioning. The same structure handles both the washing function and the containment of wash fluid, reducing the need for separate components.
Solution Approach 2:
The wash ring acts as an intermediary structure between the probe and the wash fluid reservoir. Instead of directly connecting complex fluid delivery systems to the probe, the wash ring mediates the washing process by containing wash fluid and directing it onto the probe surface in a controlled manner.
3Loss of time
If a compact wash ring structure is used to reduce probe travel distance, then processing time is reduced, but the device complexity increases
Solution Approach 1:
The wash ring combines multiple washing functions into a single integrated component. It merges the functions of wash fluid containment, fluid delivery, probe exterior washing, and probe tip cleaning into one compact structure, reducing the number of separate components needed.
Solution Approach 2:
The wash ring structure is designed to self-regulate wash fluid flow and distribution. The geometry of the wash ring and its positioning relative to the probe create automatic alignment and fluid distribution patterns, reducing the need for complex control mechanisms.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The wash ring assembly effectively reduces the time required for probe washing and drying, minimizing contamination risks and processing time by allowing simultaneous aspiration, dispensing, and cleaning of the probe during its motion, while maintaining capillary action for thorough fluid removal and prevention of dripping.
Implementation Method 1
a capillary is formed between the probe and the inner surface
Data Source
Figure 1
Figure 2A~2D
Figure 3A~3C
AI summary
Devices, including a wash ring assembly, and methods are provided for the removal of excess fluid or solids from the exterior or interior of a probe used to transfer fluids, for instance, in an automated assay device. Typically, a probe is used to aspirate and dispense a sample fluid material such as whole blood or a reagent. The devices and methods provided herein are useful for removing excess fluid from the exterior or interior of the probe so as to prevent dripping and cross-contamination between samples or reagents. It is also contemplated that, utilizing the devices and methods provided herein, washing and/or drying can be performed simultaneously as the probe is in motion, aspirating a sample and/or dispensing a sample.