Water-Based Inhalation Composition for Low-Toxicity Vaporization
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Solution Overview
Problem
Existing inhalation devices, including electronic cigarettes, pose health risks due to toxic substances like propylene glycol and glycerol, and are not suitable for delivering medical substances safely and effectively.
Innovation Solution
A medical composition comprising water, 1,3-propanediol, hyaluronic acid, and botanical extracts, designed for use in a personal vaporizer, which avoids toxicity and ensures compatibility with electronic devices by using high water content and hyaluronic acid to maintain low operating temperatures and prevent pyrolysis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If propylene glycol and glycerol are used as basic composition in electronic cigarettes, then the vapor density is sufficient, but the toxicity to respiratory tract cells increases
Solution Approach 1:
The patent changes the chemical composition parameters by replacing propylene glycol and glycerol with a water-based formulation containing 1,3-propanediol and hyaluronic acid, maintaining vapor density while eliminating cytotoxicity. This parameter substitution resolves the contradiction between sufficient vapor density and reduced respiratory tract cell toxicity.
2Ease of operation
If electronic cigarettes are used for dispensing medical substances, then portability is improved, but the toxicity of the basic composition remains a problem
Solution Approach 1:
The patent extracts and removes the toxic components (propylene glycol and glycerol) from the basic composition, replacing them with safe alternatives. This extraction of harmful substances allows the portable electronic cigarette device to be used for medical substance dispensing without the toxicity problem, resolving the contradiction between portability and composition safety.
3Object-affected harmful factors
If high water content is used in the composition, then cytotoxicity is reduced, but the operating temperature may increase
Solution Approach 1:
The patent introduces 1,3-propanediol and hyaluronic acid as intermediary substances that mediate between water and the heating element. These intermediaries have favorable thermal properties that allow high water content (reducing cytotoxicity) while maintaining controlled operating temperatures suitable for personal vaporizer devices.
4Ease of operation
If the composition is designed for personal vaporizer use, then portability is improved, but pyrolysis may occur at high temperatures
Solution Approach 1:
The patent changes the thermal stability parameters of the composition by selecting ingredients (1,3-propanediol, hyaluronic acid, botanical extracts) with high decomposition temperatures. This parameter optimization allows the composition to remain stable at personal vaporizer operating temperatures, preventing pyrolysis while maintaining portability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition provides a safe and effective delivery system for medical substances, ensuring low cytotoxicity, high biocompatibility, and compatibility with personal vaporizers, while maintaining therapeutic efficacy.
Implementation Method 1
maintaining low operating temperatures and prevent pyrolysis
Implementation Method 2
personal vaporizer... vaporize a liquid
Data Source
AI summary
The present invention relates to a liquid medical composition for inhalation. In particular, the present invention relates to a medical composition for inhalation comprising the following components : a) water 40-75% by weight b) 1, 3-propanediol 10-40% by weight c) hyaluronic acid or a salt thereof 0.05-0.5% by weight d) optionally, a preservative 0.2-0.5% by weight e) optionally, sorbitol 0.1-5% by weight f) optionally, one or more active substances 1-30% by weight