Wound Array Variables Evaluation System for Simultaneous Testing

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Solution Overview

Problem

Current wound treatment technologies face challenges in effectively evaluating and controlling bacterial adherence, moisture retention, and surface contact properties, which are crucial for wound healing outcomes, as existing methods lack comprehensive and dynamic testing capabilities.

Innovation Solution

A system and method utilizing multiple arrays of wells connected to negative pressure wound therapy (NPWT) systems for in vitro and in vivo testing, allowing for the evaluation of bacterial control, moisture control, and surface contact properties of various wound treatment variables, including the use of dynamic variables like negative pressure and controlled environments to mimic clinical conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If multiple wound treatment variables are tested simultaneously using conventional methods, then the evaluation becomes more comprehensive, but the complexity of the testing system increases significantly

Engineering Contradiction:
Improveevaluation comprehensivenessVSAvoidtesting system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The testing system is segmented into multiple independent well arrays, where each well can accommodate different wound treatment variables. This allows comprehensive testing of multiple variables simultaneously while maintaining manageable complexity through modular design. Each well functions as an independent testing unit that can be configured for specific evaluations.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The well array system serves multiple functions: it can test bacterial adherence, moisture control, surface contact properties, and various other wound treatment variables using the same basic platform. The universal design allows different dressings and treatment conditions to be evaluated within a single integrated system.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If dynamic variables such as negative pressure are applied to simulate clinical conditions, then the realism of testing improves, but the difficulty of detecting and measuring performance parameters increases

Engineering Contradiction:
Improveclinical condition simulationVSAvoidperformance parameter measurement
Core Design Contradiction:
ReliabilityVSDifficulty of detecting and measuring

Solution Approach 1:

The system uses intermediary components such as semipermeable membranes and collection reservoirs to mediate between the negative pressure application and the measurement processes. These intermediaries facilitate the detection of performance parameters by converting complex clinical conditions into measurable outputs while maintaining the realism of the simulated environment.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If comprehensive testing of bacterial control, moisture control, and surface contact properties is conducted, then the quality of wound treatment evaluation improves, but the time required for testing increases

Engineering Contradiction:
Improveevaluation qualityVSAvoidtesting duration
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The testing system enables continuous evaluation of multiple wound treatment variables simultaneously across different wells. Instead of sequential testing, the system performs continuous parallel measurements of bacterial control, moisture control, and surface contact properties, significantly reducing total testing time while maintaining comprehensive evaluation quality.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables comprehensive testing and evaluation of wound treatment materials, providing insights into bacterial behavior, moisture management, and surface interactions, thereby aiding in the development of more effective wound healing strategies.

Implementation Method 1

connected to negative pressure wound therapy (NPWT) systems for in vitro and in vivo testing, allowing for the evaluation of bacterial control, moisture control, and surface contact properties of various wound treatment variables, including the use of dynamic variables like negative pressure

Methodology Applied
Scientific EffectNegative pressure: Pressure Drop

Data Source

PatentUS10420847B2System and method for wound array variables evaluation (WAVE)
Publication Date: 2019.09.24 ZAM RES
  • US10420847B2 patent drawing
  • US10420847B2 patent drawing
  • US10420847B2 patent drawing

AI summary

A system and method for evaluating wound healing dressings, treatments, and other variables. The present invention includes in vitro systems and methods for testing wound dressing materials for bacterial control, moisture control, and surface contact properties. The present invention further includes in vivo systems and methods for testing wound dressings, treatments, and other variables utilizing arrays of wound wells on an experimental subject animal. Wound arrays allow for different wound healing variables to be tested with numerous experimental trials within the same subject animal, giving reliable results and reducing the number of subject animals required for testing.