Wavefront-Guided Laser Ablation for High-Order Aberration Correction

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Solution Overview

Problem

Current refractive surgery systems often introduce or amplify high-order optical aberrations, which can reduce visual acuity and are not effectively corrected by traditional optical correction methods like glasses or contact lenses.

Innovation Solution

A method and system for inhibiting refractive surgery-induced aberrations by adjusting refractive surgery system parameters such as wavefront device variables, laser ablation profile variables, and microkeratome variables to optimize the ablation profile and registration accuracy, thereby reducing post-operative high-order aberrations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional refractive surgery is performed, then refractive errors are corrected, but high-order aberrations are introduced or amplified

Engineering Contradiction:
Improverefractive error correctionVSAvoidhigh-order aberrations
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent applies preliminary anti-action by pre-calculating and applying an inverse aberration profile to the ablation treatment. The system measures the patient's pre-existing high-order aberrations using wavefront sensing, then designs an ablation pattern that intentionally introduces opposite aberrations to cancel out the pre-existing ones, thereby preventing net high-order aberrations after surgery.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The patent utilizes parameter changes by modifying the laser ablation profile parameters based on wavefront measurement data. The system adjusts ablation depth, spot size, and scanning patterns dynamically to compensate for measured high-order aberrations, transforming the standard ablation protocol into a customized treatment that addresses individual patient aberration profiles.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If wavefront-guided custom ablation is used to correct high-order aberrations, then visual acuity improves, but system complexity increases

Engineering Contradiction:
Improvevisual acuityVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies universality by integrating multiple functions into a unified wavefront-guided surgery system. The system combines wavefront sensing, aberration analysis, customized ablation profile generation, and laser delivery control into a single integrated platform, allowing one system to perform measurement, diagnosis, treatment planning, and execution without requiring separate independent devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent implements feedback by using wavefront sensing to measure the patient's actual optical aberrations, then using this measurement data to dynamically adjust and optimize the ablation treatment in real-time. The system continuously monitors and refines the ablation profile based on measured aberration parameters, creating a closed-loop control system that adapts to individual patient characteristics.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If laser ablation parameters are optimized to reduce high-order aberrations, then post-operative visual quality improves, but treatment time increases

Engineering Contradiction:
Improvepost-operative visual qualityVSAvoidtreatment time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by performing comprehensive wavefront measurements and ablation profile calculations before the actual laser treatment begins. The system pre-determines the optimal ablation pattern, spot size, and scanning velocity based on pre-operative measurements, allowing the actual laser ablation to proceed efficiently without real-time adjustments or interruptions.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent utilizes dynamics by implementing adaptive laser scanning patterns that dynamically adjust scanning velocity and spot dwell time based on the prescribed ablation profile. The system varies the scanning speed across different corneal regions, spending more time on areas requiring greater ablation depth while moving faster through regions needing minimal treatment, thereby optimizing overall treatment efficiency.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The approach effectively reduces post-operative high-order aberrations, achieving a total high-order RMS of less than 0.1 μm, improving visual acuity and addressing the limitations of traditional correction methods.

Implementation Method 1

laser ablation profile variable

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Data Source

PatentUS10238537B2Systems and methods for correcting high order aberrations in laser refractive surgery
Publication Date: 2019.03.26 AMO MFG USA INC
  • US10238537B2 patent drawing
  • US10238537B2 patent drawing
  • US10238537B2 patent drawing

AI summary

Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.