Waveguide Interferometry for Accurate Sample Testing

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Solution Overview

Problem

Existing methods, apparatus, and systems for sample testing face challenges due to structural limitations, environmental temperature, and contamination, affecting efficiency and accuracy.

Innovation Solution

The use of interferometry with a waveguide and integrated optical components, including a collimator and beam splitter, to detect viral indicators and protein content in samples, combined with a lens array and imaging components to analyze interference fringe patterns, and a computer-implemented method to derive refractive index data for sample identification.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If interferometry with waveguide and integrated optical components is used, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidstructural complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent integrates multiple optical components (collimator, beam splitter, lens array, imaging components) directly onto the waveguide structure, merging previously separate components into a unified integrated system. This integration maintains the high measurement precision of interferometry while reducing the overall device complexity by eliminating separate mounting and alignment mechanisms.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The waveguide acts as an intermediary element that guides light between the light source and the sample, enabling precise interferometric measurements without requiring complex external optical alignment. The integrated optical components on the waveguide surface serve as mediators that simplify the optical path while maintaining measurement accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Manufacturing precision

If integrated optical components are used on waveguide, then manufacturing precision is improved, but ease of manufacture deteriorates

Engineering Contradiction:
Improvecomponent integration precisionVSAvoidmanufacturing difficulty
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The device is designed as a modular cartridge that can be manufactured and tested separately, then integrated into the larger testing system. This segmentation allows for specialized manufacturing processes for the waveguide and optical components while simplifying the overall assembly process, balancing manufacturing precision requirements with ease of manufacture.

Inventive Principle:
Principle #1Segmentation

3Productivity

If advanced optical analysis and data processing are used, then productivity is improved, but device complexity increases

Engineering Contradiction:
Improvetesting efficiencyVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system includes automated data processing and analysis capabilities that perform refractive index calculations and sample identification without requiring manual intervention. The computer-implemented methods automatically process interferometric data, derive refractive index values, and identify samples, improving productivity while the integration of these functions into the device architecture minimizes the perceived complexity for the user.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enhances the efficiency and accuracy of sample testing by providing precise detection of viral indicators and protein content through advanced optical analysis and data processing techniques.

Implementation Method 1

In some embodiments, example methods, apparatuses, and systems may utilize interferometry to detect the presence of virus and/or other viral indicator of protein content in a collected sample.

Methodology Applied
Scientific EffectInterferometry: Interference

Data Source

PatentUS12422361B2Apparatuses, systems, and methods for sample testing
Publication Date: 2025.09.23 HAND HELD PRODS INC
  • US12422361B2 patent drawing
  • US12422361B2 patent drawing
  • US12422361B2 patent drawing

AI summary

Methods, apparatuses, and systems associated with a sample testing device are provided. For example, an example sample testing device may include a substrate layer defining a bottom surface of the sample testing device, as well as a waveguide disposed on the substrate layer and includes at least one reference channel and at least one sample channel.