Wavy Annular Vessel Holder for Multi-Point Baroreceptor Stimulation
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Solution Overview
Problem
Existing implantable medical devices fail to effectively expand blood vessels in multiple directions, leading to insufficient mechanical stimulation of baroreceptors, particularly in cases where the autonomic nerve function is deteriorated, resulting in hypertension.
Innovation Solution
An implantable medical device with a blood vessel holding unit featuring an annular structure comprising wavy linear components with shifted first and second curved portions, allowing for efficient expansion and contraction to apply mechanical stimulation to baroreceptors, and a delivery device for precise placement and retrieval.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If the blood vessel is formed into a polygonal shape with limited stimulation points, then the device structure is simple, but the mechanical stimulation to baroreceptor is insufficient and therapeutic effect cannot be obtained
Solution Approach 1:
The blood vessel holding unit is divided into multiple independent curved portions (first curved portions and second curved portions) that can be arranged in various patterns. This segmentation allows the device to provide multiple discrete stimulation points along the blood vessel wall, increasing the number of baroreceptor stimulation locations while maintaining a relatively simple overall structure.
Solution Approach 2:
The invention applies curved portions with different characteristics (protruding toward proximal end or distal end) at different locations along the blood vessel holding unit. This local variation in structure creates diverse stimulation patterns at different sites, enhancing the mechanical stimulation effectiveness on baroreceptors without requiring a completely complex device design.
2Reliability
If the number of stimulation points on the blood vessel wall is increased, then mechanical stimulation can be more effectively applied to baroreceptor, but the device structure becomes more complex
Solution Approach 1:
The blood vessel holding unit is divided into multiple independent curved portions (first curved portions and second curved portions) that can be arranged in various patterns. This segmentation allows the device to provide multiple discrete stimulation points along the blood vessel wall, increasing the number of baroreceptor stimulation locations while maintaining a relatively simple overall structure.
Solution Approach 2:
The curved portions are arranged not only in the circumferential direction but also in the axial direction along the blood vessel holding unit. This multi-dimensional arrangement allows the device to increase the number of stimulation points without simply adding more components in one direction, thereby controlling device complexity while enhancing stimulation effectiveness.
3Shape
If the blood vessel is not uniformly cylindrical, then the expansion obtained in the radial direction is not uniform, but the existing device cannot provide sufficient mechanical stimulation to baroreceptor
Solution Approach 1:
The invention applies curved portions with different characteristics (protruding toward proximal end or distal end) at different locations along the blood vessel holding unit. This local variation in structure creates diverse stimulation patterns at different sites, enhancing the mechanical stimulation effectiveness on baroreceptors without requiring a completely complex device design.
Solution Approach 2:
The blood vessel holding unit is designed to be expandable and contractible, allowing it to adapt to the non-uniform shape of the blood vessel. When expanded, the curved portions make contact with the blood vessel wall at multiple points, providing dynamic mechanical stimulation that accommodates variations in blood vessel geometry.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device efficiently extends blood vessels in multiple directions, increasing stimulation points and ensuring effective mechanical stimulation to baroreceptors, thereby reducing blood pressure effectively.
Implementation Method 1
a blood vessel holding unit that is capable of expanding and contracting to apply mechanical stimulation to a blood vessel wall of the blood vessel
Data Source
AI summary
An implantable medical device includes the blood vessel holding unit capable of expanding and contracting to apply mechanical stimulation to the blood vessel wall of a blood vessel, the blood vessel holding unit has an annular structure in which a wavy linear component including at least one or more first curved portions protruding toward the proximal end side, at least one or more second curved portions protruding toward the distal end side, and at least one or more linear first connecting portions connecting the first curved portion and the second curved portion is annular, the first curved portion forms at least one or more first apex portions in the radial direction of the central axis of the annular structure, the second curved portion forms at least one or more second apex portions in the radial direction of the central axis of the annular structure.