Wearable Biosensor with Cell Layer for Non-Invasive Monitoring
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Solution Overview
Problem
Existing wearable biosensors for monitoring physiological changes require surgical implantation, leading to hospitalization and downtime, necessitating a non-invasive solution for continuous and extended monitoring.
Innovation Solution
A wearable device with a housing secured to the body, featuring a needle for fluid contact, a chamber with a cell layer to monitor bodily fluids, and a reader to decode signals, allowing for two-way communication and temperature control, enabling continuous monitoring without surgical implantation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If surgical implantation is used to monitor physiological changes, then monitoring reliability is improved, but patient downtime and discomfort increase
Solution Approach 1:
The patent replaces the mechanical surgical implantation system with a wearable device system that uses adhesive attachment and transdermal fluid access. The wearable housing with needle assembly substitutes for traditional surgical implants, allowing physiological monitoring without incisions or stitches, thereby eliminating hospitalization and reducing patient downtime while maintaining monitoring reliability.
2Measurement precision
If surgical implantation is used to monitor physiological changes, then monitoring precision is improved, but device complexity and procedure difficulty increase
Solution Approach 1:
The monitoring system is segmented into separate functional modules: a wearable housing containing the needle assembly, a separate chamber for cell layer integration, and an external reader device. This segmentation allows each component to be optimized independently while simplifying the overall implantation procedure, as the wearable portion can be attached externally without complex surgical steps, yet maintains physiological monitoring precision through the integrated cell layer and fluid access mechanism.
3Reliability
If traditional biosensors are used, then physiological monitoring capability is achieved, but patient comfort and ease of use deteriorate due to surgical requirements
Solution Approach 1:
The patent introduces a wearable intermediate device that bridges the gap between external monitoring and internal physiological measurements. The wearable housing with transdermal needle access serves as an intermediary, allowing the device to obtain bodily fluids for analysis without requiring full surgical implantation, thereby maintaining physiological monitoring capability while dramatically improving patient comfort and ease of application through non-invasive attachment methods.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device provides continuous, extended, and non-invasive monitoring of physiological changes, improving patient care by minimizing downtime and discomfort, and enabling personalized diagnosis and treatment.
Implementation Method 1
a chamber having a cell layer and configured to monitor physiological changes in the bodily fluid and to generate one or more signals associated with the physiological changes
Implementation Method 2
The light source can illuminate light onto the cell layer thereby causing certain cells within the cell layer to emit light
Data Source
AI summary
A wearable device for monitoring physiological changes in a patient is provided. The device can include a housing adapted to being secured to a patient's body, the housing comprising a needle configured for fluid contact with a bodily fluid under a skin surface; a chamber having a cell layer and configured to monitor physiological changes in the bodily fluid and to generate one or more signals associated with the physiological changes; and a reader for detecting and/or decoding signals from the cell layer to monitor physiological changes in the patient. The device is capable of engaging in a two-way communication with a second device through transmission of one or more signals.