Wearable Opioid Overdose Detection with Automatic Drug Delivery

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Solution Overview

Problem

Current methods lack an effective and immediate solution for detecting opioid overdose and automatically administering therapeutic drugs, particularly in situations where the user is alone and unable to seek help, leading to potential life-threatening respiratory depression.

Innovation Solution

A wearable system combining a sensor to monitor physiological parameters, a signal processor to analyze data, and a drug delivery apparatus that automatically dispenses a therapeutic drug when predetermined thresholds are met, along with a medical monitoring hub that alerts responders and contacts emergency services.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a wearable monitoring system with automatic drug delivery is implemented, then the reliability of opioid overdose detection and response is improved, but the device complexity increases

Engineering Contradiction:
Improveoverdose detection reliabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system is divided into separate functional modules: a sensor module for physiological monitoring, a signal processing module for data analysis, a drug delivery apparatus for automatic medication administration, and a medical monitoring hub for alerts and communications. This segmentation allows each component to be optimized independently while maintaining overall system reliability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system performs preliminary monitoring and analysis of physiological parameters continuously, establishing baseline data and detecting early signs of respiratory depression before full overdose occurs. This enables proactive intervention rather than reactive response, improving detection reliability.

Inventive Principle:
Principle #10Preliminary action

2Speed

If continuous physiological monitoring is performed to enable early detection, then the speed of overdose detection is improved, but the use of energy increases

Engineering Contradiction:
Improvedetection speedVSAvoidenergy consumption
Core Design Contradiction:
SpeedVSUse of energy by moving object

Solution Approach 1:

The monitoring system operates periodically rather than continuously at full capacity, cycling through different monitoring intensities and analyzing data at optimized intervals. This approach maintains fast detection capability while significantly reducing overall energy consumption compared to uninterrupted high-frequency monitoring.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The system replaces complex mechanical monitoring mechanisms with optical sensing and computational analysis, using light-based oximetry and algorithmic pattern recognition to detect respiratory depression. This substitution reduces energy consumption while maintaining or improving detection speed.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If automatic drug delivery is implemented to reduce response time, then the productivity of emergency response is improved, but the device complexity increases

Engineering Contradiction:
Improveemergency response efficiencyVSAvoidautomation complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system provides self-service through automatic detection of overdose conditions and autonomous administration of therapeutic drugs without requiring manual intervention. The drug delivery apparatus is triggered automatically when physiological parameters indicate respiratory depression, enabling immediate response while reducing the complexity of manual operation procedures.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

A medical monitoring hub acts as an intermediary between the sensor system and drug delivery apparatus, processing data and coordinating the automatic response. This intermediary layer manages the complexity of automation while maintaining streamlined emergency response productivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enables early detection of opioid overdose, automatic administration of therapeutic drugs, and timely notification of emergency services, significantly reducing the risk of irreversible harm or death.

Implementation Method 1

the sensor has light emitting diodes (LEDs) that transmit optical radiation into a tissue site and a detector that responds to the intensity of the optical radiation after absorption (e.g., by transmission or transflectance) by, for example, pulsatile arterial blood flowing within the tissue site

Methodology Applied
Scientific EffectAbsorption (EM radiation): Absorption (EM radiation)

Implementation Method 2

a processor can determine measurements for peripheral oxygen saturation (SpO2), which is an estimate of the percentage of oxygen bound to hemoglobin in the blood, pulse rate, plethysmograph waveforms, which indicate changes in the volume of arterial blood with each pulse beat

Methodology Applied
Scientific EffectPhotoplethysmography:

Data Source

PatentUS20220296161A1Time-based critical opioid blood oxygen monitoring
Publication Date: 2022.09.22 MASIMO CORP
  • US20220296161A1 patent drawing
  • US20220296161A1 patent drawing
  • US20220296161A1 patent drawing

AI summary

A system for critical time-based opioid monitoring system includes a physiological monitoring system having a sensor and a system processing board, a computing device configured to receive the parameters, an indication of normal conditions of a user under the circumstances at the time, such as, for example, a body transfer function or user physiological parameter model, to compare the monitored parameters to the normal conditions, and sending a notification when the monitored parameters deviate from the normal condition of a user. A system to monitor for an opioid event includes a physiological monitoring system comprising a sensor configured to monitor physiological parameters and a signal processing board, a computing device to detect an opioid overdose, and a device to stimulate a response when the computing device detects an opioid overdose event is occurring.