Wearable Pain Measurement Using Contralateral Sensor Differentials

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Solution Overview

Problem

Current methods lack an objective and reliable way to quantify an individual's experience of pain, which is influenced by biological, psychological, and social factors, leading to inadequate diagnosis and treatment of chronic pain, particularly in populations that struggle with communication, and there is a need for at-home monitoring and telemedicine to assess pain and treatment effectiveness.

Innovation Solution

A pain measurement and diagnostic system (PMD) using wearable devices with sensors to measure physiological parameters and integrate them with biopsychosocial data, providing a quantitative measure of pain through the 'pain matrix' activity, correlating with self-report scales and allowing for personalized treatment interventions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If subjective pain scales (NRS, VAS) are used to measure pain, then the measurement method is simple and easy to implement, but the measurement precision and objectivity are insufficient

Engineering Contradiction:
Improveease of implementationVSAvoidobjectivity of pain measurement
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent introduces an intermediary device (pain measurement device with sensors) that mediates between the patient's subjective pain experience and the objective measurement. The device includes sensors that detect physiological parameters (heart rate, skin conductance, temperature, muscle activity) and process these signals to generate an objective pain score, serving as a mediator that translates subjective experience into quantifiable data without requiring complex patient self-reporting

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the mechanical/subjective system of patient self-reporting with an electronic/automated sensor-based system. Instead of relying on patient verbal or numerical reports, the system uses electronic sensors to detect physiological signals and automatically processes these signals through algorithms to generate pain measurements, substituting the manual subjective assessment mechanism with an automated objective one

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If multiple biosensors are integrated to measure multiple physiological parameters, then the measurement precision and comprehensiveness improve, but the device complexity increases

Engineering Contradiction:
Improvecomprehensiveness of pain assessmentVSAvoidnumber of sensors and processing components
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent merges multiple sensor functions and processing operations into a single integrated device. The pain measurement device combines heart rate sensors, skin conductance sensors, temperature sensors, and muscle activity sensors into one unit, along with integrated signal processing and analysis capabilities. This consolidation achieves comprehensive multi-parameter monitoring while managing device complexity through integration rather than separate components

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The pain measurement device is designed with multi-functionality, serving as a universal platform that can measure multiple physiological parameters (heart rate, skin conductance, temperature, muscle activity) simultaneously. This single device performs multiple assessment functions that would otherwise require separate instruments, reducing overall system complexity while maintaining comprehensive measurement capabilities

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If at-home monitoring with wearable devices is implemented, then patient monitoring capability and treatment validation improve, but the reliability of measurements in uncontrolled environments may deteriorate

Engineering Contradiction:
Improvepatient monitoring capabilityVSAvoidmeasurement consistency in uncontrolled environments
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent implements feedback mechanisms where the device continuously monitors physiological parameters and provides real-time or near-real-time pain assessments. The system collects data from multiple sensors, processes signals through algorithms that account for environmental variations, and generates feedback in the form of pain scores that can be reviewed by patients and healthcare providers. This feedback loop enables continuous monitoring and adjustment, maintaining measurement reliability despite uncontrolled home environments

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent employs parameter changes in the form of signal processing algorithms that adapt to different environmental conditions. The device measures multiple physiological parameters simultaneously and uses ratio-based or differential calculations that cancel out environmental noise. For example, by comparing skin conductance changes relative to baseline or comparing multiple physiological signals against each other, the system maintains measurement reliability across varying home environments without requiring controlled conditions

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The PMD system objectively measures pain, facilitating accurate diagnosis and treatment, improving patient monitoring and treatment compliance, and reducing the risk of under-treatment by integrating biophysical and psychological data for personalized healthcare.

Implementation Method 1

By measuring EDA using the contralateral placement of sensors, or electrodes, direct measurements of brain pain processing from the 'pain matrix' demonstrate

Methodology Applied
Scientific EffectElectrodermal activity:

Implementation Method 2

a galvanic skin response measurement device

Methodology Applied
Scientific EffectGalvanic skin response:

Data Source

PatentEP4652921A1Method and apparatus for the measurement of autonomic function for the diagnosis and validation of patient treatments and outcomes
Publication Date: 2025.11.26 DULLEN DEBORAH
  • EP4652921A1 patent drawingFigure 1
  • EP4652921A1 patent drawingFigure 2
  • EP4652921A1 patent drawingFigure 3

AI summary

The present invention relates to a pain measurement and diagnostic system (10), comprising a device (14, 67, 303, 305, 320, 336), with a sensor set (35, 41, 43, 59, 81, 310, 315, 322, 330, 352), wherein the sensor set (35, 41, 43, 59, 81, 310, 315, 322, 330, 352) comprises: - at least one pair of sensors (35, 41, 43, 59, 81, 310, 315, 322, 330, 352), placed contralaterally on the body of an individual configured to provide measurements of electrical activity due to neural transmissions to and from the brain and processing of brain region activity to measure the differential between the at least one pair of sensors (35, 41, 43, 59, 81, 310, 315, 322, 330, 352) placed contralaterally; - a power supply (406, 368).