Wearable Perfusion Index via Occlusion Baseline

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Solution Overview

Problem

Current devices for monitoring peripheral blood flow provide relative measurements that are difficult to interpret clinically, especially when a 'healthy' baseline cannot be obtained, and are affected by skin color, leading to inconsistent measurements.

Innovation Solution

A method and system for monitoring peripheral blood flow using a wearable device that involves monitoring blood flow under two different physiologic conditions, generating a dimensionless relative index based on these measurements, and outputting an indication of this index.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If relative measurements are used for monitoring peripheral blood flow, then device complexity is reduced, but measurement precision deteriorates due to difficulty in clinical interpretation

Engineering Contradiction:
Improvedevice complexityVSAvoidmeasurement precision
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent transforms the measurement parameter from absolute blood flow values to a dimensionless relative index by introducing a reference measurement (occlusion baseline). This parameter transformation enables clinical interpretation while maintaining device simplicity, as the index represents blood flow as a percentage of the reference state rather than requiring complex absolute quantification

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If absolute blood flow measurements are implemented, then measurement precision improves, but device complexity increases due to requirements for healthy baseline acquisition

Engineering Contradiction:
Improvemeasurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system performs self-calibration by using the patient's own occluded state as the reference baseline, eliminating the need for external healthy baseline data. The device automatically establishes its own reference point through the occlusion maneuver, making the system self-sufficient and removing dependencies on external calibration sources

Inventive Principle:
Principle #25Self-service

3Ease of operation

If traditional blood loss estimation methods are used, then ease of operation is maintained, but measurement precision deteriorates due to underestimation of blood loss

Engineering Contradiction:
Improveease of operationVSAvoidmeasurement precision
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent replaces visual estimation (mechanical observation) with optical measurement using photodetectors and light sources. This substitution maintains operational simplicity as the device automatically performs measurements and calculations, while dramatically improving precision by providing objective quantitative data on blood flow changes and blood loss

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Device complexity

If skin color effects are not compensated, then device complexity remains low, but measurement precision deteriorates due to inconsistent measurements across different skin tones

Engineering Contradiction:
Improvedevice complexityVSAvoidmeasurement precision
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent introduces an intermediary reference measurement (occlusion baseline) that serves as a mediator between the light source and the blood flow measurement. This reference state captures the skin's optical properties under known conditions, allowing the system to compensate for skin color variations by comparing measurements against this personalized reference rather than requiring complex skin tone detection algorithms

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides subject-specific perfusion range measurements that are not affected by skin color, enabling accurate monitoring of peripheral blood flow and early detection of conditions like postpartum hemorrhage.

Implementation Method 1

a photodetector to detect the intensity of light transmitted through the tissue

Methodology Applied
Scientific EffectPhotodetection: Photoelectric Effect

Data Source

PatentUS20250064333A1Normalization and Calibration for Devices and Systems for Measuring Peripheral Hemodynamics
Publication Date: 2025.02.27 WASHINGTON UNIV IN SAINT LOUIS
  • US20250064333A1 patent drawing
  • US20250064333A1 patent drawing
  • US20250064333A1 patent drawing

AI summary

A method for monitoring peripheral blood flow of a patient using a wearable device includes monitoring peripheral blood flow of the patient under a first physiologic condition and monitoring peripheral blood flow of the patient under a second physiologic condition different than the first physiologic condition. A dimensionless relative index of the monitored peripheral blood flow of the patient i) under the second physiologic condition based on the monitored peripheral blood flow under the first physiologic condition, or ii) under the first physiologic condition based on the monitored peripheral blood flow under the second physiologic condition is generated. An indication of the dimensionless relative index is output.