Wearable Pumping Chamber Assembly for Controlled Therapeutic Flow

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Solution Overview

Problem

Existing portable devices for controlled release of therapeutics suffer from malfunctions, size, weight, and cost issues, and require complex designs for administering medications like insulin, which are not orally active due to absorption issues or require frequent administration.

Innovation Solution

A wearable fluid delivery system with a pumping chamber and force application assembly that restricts retrograde flow, using shape-memory actuators to pressurize the chamber and ensure unidirectional flow, integrated with a tortuous conduit and passive valves for precise fluid delivery, and a sensor for flow measurement to adjust operation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If a wearable device is designed for controlled release of therapeutics, then the need for frequent administration is reduced and patient compliance improves, but the device size, weight, and complexity increase

Engineering Contradiction:
Improveduration of therapeutic deliveryVSAvoiddevice complexity
Core Design Contradiction:
Duration of action of moving objectVSDevice complexity

Solution Approach 1:

The force application assembly combines multiple functions (occluding the inlet line to restrict retrograde flow and pressurizing the pumping chamber to urge flow through the outlet) into a single mechanical action, reducing the number of separate components and simplifying the overall device structure while maintaining controlled release capability

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The force application assembly serves multiple purposes: it acts as both a valve actuator (by occluding the inlet line) and a pump actuator (by pressurizing the pumping chamber), thereby reducing the need for separate dedicated components and lowering overall device complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Duration of action of moving object

If a wearable device is designed for controlled release of therapeutics, then the need for frequent administration is reduced and patient compliance improves, but the device weight increases

Engineering Contradiction:
Improveduration of therapeutic deliveryVSAvoiddevice weight
Core Design Contradiction:
Duration of action of moving objectVSWeight of moving object

Solution Approach 1:

The force application assembly combines multiple functions (occluding the inlet line to restrict retrograde flow and pressurizing the pumping chamber to urge flow through the outlet) into a single mechanical action, reducing the number of separate components and simplifying the overall device structure while maintaining controlled release capability

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system uses a passive valve that automatically prevents reverse flow without requiring active control or additional power, reducing the need for powered components and thereby reducing device weight while maintaining reliable unidirectional flow

Inventive Principle:
Principle #25Self-service

3Duration of action of moving object

If a wearable device is designed for controlled release of therapeutics, then the need for frequent administration is reduced and patient compliance improves, but the device size increases

Engineering Contradiction:
Improveduration of therapeutic deliveryVSAvoiddevice size
Core Design Contradiction:
Duration of action of moving objectVSVolume of moving object

Solution Approach 1:

The force application assembly combines multiple functions (occluding the inlet line to restrict retrograde flow and pressurizing the pumping chamber to urge flow through the outlet) into a single mechanical action, reducing the number of separate components and simplifying the overall device structure while maintaining controlled release capability

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The force application assembly is positioned to utilize the same mechanical stroke for multiple functions: the initial portion of the stroke occludes the inlet line while the remaining stroke pressurizes the pumping chamber, effectively nesting multiple functions within a single mechanical sequence and minimizing space requirements

Inventive Principle:
Principle #7Nested doll (Nesting)

4Ease of operation

If existing portable devices are used for controlled release of therapeutics, then administration of medications like insulin is enabled, but the malfunction rate increases

Engineering Contradiction:
Improveease of medication administrationVSAvoiddevice reliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system uses a passive valve that automatically prevents reverse flow without requiring active control or additional power, reducing the number of powered components and potential failure points while ensuring reliable unidirectional flow

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The force application assembly combines multiple functions (occluding the inlet line to restrict retrograde flow and pressurizing the pumping chamber to urge flow through the outlet) into a single mechanical action, reducing the number of separate components and potential failure points while maintaining controlled release capability

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system provides reliable, efficient, and controlled delivery of therapeutic fluids over time, reducing the need for frequent administration and improving patient compliance by minimizing device size and weight while enhancing reliability and precision.

Implementation Method 1

using a shape-memory actuator. Also optionally, using the shape-memory actuator includes inducing a phase change in a shape memory wire to transmit a force around a pulley to the force application assembly

Methodology Applied
Scientific EffectShape memory: Shape Memory Alloy

Data Source

PatentUS11813427B2Pumping fluid delivery systems and methods using force application assembly
Publication Date: 2023.11.14 DEKA PRODUCTS LP
  • US11813427B2 patent drawing
  • US11813427B2 patent drawing
  • US11813427B2 patent drawing

AI summary

A method of dispensing a therapeutic fluid from a line includes providing an inlet line connectable to an upstream fluid source. The inlet line is in downstream fluid communication with a pumping chamber. The pumping chamber has a pump outlet. The method also includes actuating a force application assembly so as to restrict retrograde flow of fluid through the inlet while pressurizing the pumping chamber to urge flow through the pump outlet. A corresponding system employs the method.