Wheat Cultivar BZ6W07-458 Backcrossing Trait Introgression

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Solution Overview

Problem

Current wheat cultivars lack effective methods for introducing desirable traits such as herbicide tolerance, pest resistance, disease resistance, and modified metabolisms, which are essential for improving yield and stress tolerance.

Innovation Solution

The development of the wheat cultivar BZ6W07-458, which involves crossing with other wheat cultivars to introduce desired traits through backcrossing and genetic engineering, allowing for the incorporation of traits like herbicide resistance, insect resistance, disease resistance, and modified metabolisms, while maintaining the physiological and morphological characteristics of BZ6W07-458.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional wheat cultivars are used, then existing yield and stress tolerance levels are maintained, but effective methods for introducing desirable traits such as herbicide tolerance, pest resistance, and disease resistance are lacking

Engineering Contradiction:
Improvetrait introduction capabilityVSAvoidyield and stress tolerance
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent uses backcrossing as an intermediary breeding method to transfer desirable traits from donor cultivars into the BZ6W07-458 cultivar. Through repeated backcrossing generations (BC1, BC2, BC3), the method mediates between the existing cultivar and donor plants with desired traits, gradually incorporating herbicide tolerance, pest resistance, and disease resistance while maintaining the physiological and morphological characteristics of the original cultivar

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent performs preliminary selection of parent plants with specific desired traits before initiating the backcrossing program. Donor cultivars are pre-selected for particular characteristics such as herbicide tolerance or pest resistance, and molecular markers are pre-established to track trait inheritance, enabling efficient introgression of desirable traits into the target cultivar

Inventive Principle:
Principle #10Preliminary action

2Reliability

If backcrossing and genetic engineering are used to introduce desired traits, then resistance to various stresses and improved agronomic traits are achieved, but the complexity of the breeding process increases

Engineering Contradiction:
Improveresistance to stressesVSAvoidbreeding process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent implements feedback mechanisms through molecular marker-assisted selection during the backcrossing process. Specific molecular markers are used to monitor the inheritance of desired traits and the recovery of the recurrent parent genome. This feedback allows breeders to make informed decisions at each generation, selecting plants that have both the desired stress resistance traits and sufficient genetic similarity to the original cultivar, thereby streamlining the complex breeding process

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent changes key parameters of the breeding process by using accelerated backcrossing methods and molecular marker technology. Instead of traditional phenotypic selection alone, the process incorporates genetic marker analysis to speed up trait introgression. The number of backcrossing generations is optimized (typically 3-5 generations), and selection criteria are quantitatively defined using marker data, transforming the complex breeding process into a more controlled and efficient procedure

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If multiple backcrossing generations are performed to maintain physiological and morphological characteristics, then uniformity across generations is ensured, but the time required for trait introduction increases

Engineering Contradiction:
Improveuniformity across generationsVSAvoidbreeding cycle duration
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent performs preliminary establishment of molecular marker systems before initiating backcrossing. Markers linked to both the desired traits and key physiological/morphological characteristics are pre-identified and validated. This preliminary action allows for accelerated selection in subsequent generations, reducing the time needed to achieve uniformity while maintaining genetic stability

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent optimizes the number of backcrossing generations by changing the time parameter. Through molecular marker-assisted selection, uniformity can be achieved in fewer generations (typically 3-5 backcrosses) compared to traditional breeding methods. The patent also changes selection intensity parameters, using more rigorous marker-based selection in early generations to quickly recover the recurrent parent genome, thereby reducing overall breeding cycle duration while maintaining uniformity

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS8865984B2Plants and seeds of common wheat cultivar BZ6W07-458
Publication Date: 2014.10.21 MONSANTO TECHNOLOGY LLC

AI summary

A wheat cultivar, designated BZ6W07-458, is disclosed. The invention relates to the seeds, plants, and hybrids of wheat cultivar BZ6W07-458, and to methods for producing a wheat plant produced by crossing plants from wheat cultivar BZ6W07-458 with themselves or with plants from another wheat variety. The invention also relates to methods for producing a wheat plant containing in its genetic material one or more transgenes and to the transgenic wheat plants and plant parts produced by those methods. The invention also relates to wheat varieties or breeding varieties and plant parts derived from wheat cultivar BZ6W07-458, to methods for producing other wheat varieties, lines or plant parts derived from wheat cultivar BZ6W07-458, and to the wheat plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid wheat seeds and plants produced by crossing wheat cultivar BZ6W07-458 with another wheat cultivar.