Wheat Cultivar 01095260: Marker-Assisted Multi-Trait Breeding

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Solution Overview

Problem

Existing wheat cultivars lack improved combinations of desirable traits such as higher seed yield, disease resistance, insect resistance, drought tolerance, heat tolerance, better agronomic quality, and herbicide resistance, which are essential for enhancing wheat productivity and versatility in various applications.

Innovation Solution

Development of the wheat cultivar 01095260, which incorporates transgenic genes conferring traits like herbicide resistance, insect resistance, disease resistance, and improved nutritional quality, achieved through genetic transformation and traditional breeding techniques, along with methods like recurrent selection and genetic marker-assisted selection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional breeding techniques are used to develop wheat cultivars, then genetic diversity is maintained, but the rate of improvement for multiple desirable traits simultaneously is limited

Engineering Contradiction:
Improveseed yieldVSAvoidbreeding cycle time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent combines traditional breeding techniques with transgenic technology to simultaneously achieve multiple desirable traits (herbicide resistance, insect resistance, disease resistance, improved nutritional quality) that would take extensive conventional breeding to accomplish separately. This merging accelerates the breeding process while maintaining genetic diversity through the use of recurrent selection and genetic marker-assisted selection.

Inventive Principle:
Principle #5Merging (Combining)

2Adaptability or versatility

If multiple desirable traits are combined in a single wheat cultivar, then overall productivity and versatility improve, but the complexity of breeding program increases

Engineering Contradiction:
Improveagronomic qualityVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent uses genetic markers as intermediaries to track and select for multiple desirable traits simultaneously. Genetic marker-assisted selection allows breeders to monitor the inheritance of specific traits (herbicide resistance, insect resistance, disease resistance, nutritional quality) without having to evaluate each trait individually, thereby simplifying the management of complex multi-trait breeding programs.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If transgenic genes are introduced to confer resistance traits, then resistance to diseases and insects improves, but regulatory approval and public acceptance may become more difficult

Engineering Contradiction:
Improvedisease resistanceVSAvoidregulatory approval process
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent introduces specific transgenic genes at targeted loci to confer particular resistance traits (herbicide resistance, insect resistance, disease resistance) while maintaining the rest of the genome unchanged. This localized genetic modification allows for precise introduction of desired traits with minimal impact on other characteristics, facilitating regulatory review and public acceptance by demonstrating targeted rather than genome-wide modification.

Inventive Principle:
Principle #3Local quality

Data Source

PatentUS12419242B2Wheat cultivar 01095260
Publication Date: 2025.09.23 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the wheat cultivar designated 01095260. Provided by the invention are the seeds, plants and derivatives of the wheat cultivar 01095260. Also provided by the invention are tissue cultures of the wheat cultivar 01095260 and the plants regenerated therefrom. Still further provided by the invention are methods for producing wheat plants by crossing the wheat cultivar 01095260 with itself or another wheat cultivar and plants produced by such methods.