Hard Red Spring Wheat Cultivar With Marker-Assisted Trait Stacking

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Solution Overview

Problem

Existing wheat cultivars lack improved combinations of desirable traits such as higher seed yield, disease and insect resistance, drought tolerance, and better agronomic quality, which are essential for enhancing productivity and adaptability in various market classes.

Innovation Solution

Development of the wheat cultivar 01095188, which is a HARD RED SPRING type common wheat, incorporating genetic modifications and traditional breeding techniques to enhance traits like herbicide resistance, disease resistance, and improved nutritional quality, along with methods for producing hybrid seeds and transgenic variants.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding techniques are used to develop wheat cultivars, then genetic diversity and trait combination are limited, but breeding time and resource investment increase

Engineering Contradiction:
Improvetrait combinationVSAvoidbreeding time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent employs molecular markers as intermediary tools to identify and select plants with desired traits. These markers serve as genetic signposts that allow breeders to track inheritance of specific genes without directly observing the traits, significantly accelerating the breeding process while maintaining genetic diversity and trait combination capabilities.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces traditional phenotypic selection (mechanical observation and manual selection) with molecular marker-assisted selection. This substitution enables rapid identification of plants carrying desired genetic traits at the DNA level, reducing breeding time from multiple generations to fewer cycles while improving precision in trait combination.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Manufacturing precision

If genetic engineering is used to introduce specific traits, then trait introduction precision is improved, but regulatory complexity and public acceptance challenges increase

Engineering Contradiction:
Improvetrait introduction precisionVSAvoidregulatory complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies genetic engineering selectively only when specific traits are required, rather than universally applying it to all breeding programs. This partial use of genetic engineering maintains precision in trait introduction for critical traits while avoiding unnecessary genetic modification in cases where traditional breeding suffices, thereby reducing regulatory complexity and public acceptance barriers.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The patent modifies specific genetic parameters (individual genes or gene segments) rather than making comprehensive changes to the wheat genome. This targeted approach to genetic modification introduces only the necessary traits with high precision while minimizing unintended consequences and regulatory scrutiny associated with extensive genetic engineering.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If multiple desirable traits are combined in a single cultivar, then productivity and adaptability are enhanced, but genetic stability and uniformity may be compromised

Engineering Contradiction:
Improveseed yieldVSAvoidgenetic stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent segments the breeding process into distinct phases: first identifying individual trait genes using molecular markers, then systematically combining them through controlled crosses. This segmentation allows for careful verification of genetic stability at each stage, ensuring that multiple desirable traits are integrated without compromising the overall genetic uniformity and stability of the final cultivar.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements continuous feedback loops using molecular marker analysis throughout the breeding process. At each generation, plants are screened to verify they possess the intended trait combinations and maintain genetic uniformity. This feedback mechanism enables real-time monitoring and adjustment, ensuring that productivity enhancements from multiple trait combinations do not compromise genetic stability.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12514189B2Wheat cultivar 01095188
Publication Date: 2026.01.06 MONSANTO TECHNOLOGY LLC

AI summary

The invention relates to the wheat cultivar designated 01095188. Provided by the invention are the seeds, plants and derivatives of the wheat cultivar 01095188. Also provided by the invention are tissue cultures of the wheat cultivar 01095188 and the plants regenerated therefrom. Still further provided by the invention are methods for producing wheat plants by crossing the wheat cultivar 01095188 with itself or another wheat cultivar and plants produced by such methods.