Wheat Variety HAW12-156 CRISPR Genome Editing for Yield
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Solution Overview
Problem
Current plant breeding methods face challenges in developing wheat varieties that combine desirable traits such as high seed yield, disease resistance, and tolerance to environmental stresses, while maintaining genetic stability and adaptability.
Innovation Solution
The development of the wheat cultivar HAW12-156, which includes methods for vegetative propagation, introducing desired traits through single locus conversions, and using New Breeding Techniques like CRISPR/Cas system for genome editing, along with traditional breeding methods to create variants and mutants that exhibit improved agronomic characteristics.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If traditional breeding methods are used to combine desirable traits, then genetic diversity is improved, but breeding time and complexity increase
Solution Approach 1:
The patent replaces traditional mechanical breeding methods (crossing, selection, and regeneration over multiple generations) with CRISPR/Cas9 genome editing technology. This allows direct modification of specific genes (TaGW2-6A and TaGW2-6B) to control grain weight and yield, eliminating the need for lengthy traditional breeding programs while achieving the same genetic improvement goals.
2Productivity
If multiple traits are combined in a single variety, then agronomic performance is improved, but genetic stability becomes difficult to maintain
Solution Approach 1:
The patent segments the complex trait improvement into specific, targeted gene modifications. Instead of attempting to combine multiple traits through traditional breeding which compromises genetic stability, the invention focuses on editing specific genes (TaGW2-6A and TaGW2-6B) that control grain weight, allowing precise control over yield components while maintaining the genetic background stability of the parent variety.
3Adaptability or versatility
If conventional breeding techniques are used, then desirable traits are combined, but manufacturing precision of genetic traits deteriorates
Solution Approach 1:
The patent replaces imprecise conventional breeding techniques with precise CRISPR/Cas9 genome editing. This allows exact modification of target genes (TaGW2-6A and TaGW2-6B) at specific genomic locations, achieving precise control over grain weight and yield traits that cannot be achieved through traditional breeding methods which rely on random recombination and selection.
Data Source
AI summary
A wheat variety designated HAW12-156, the plants and seeds of wheat variety HAW12-156, methods for producing a wheat plant produced by crossing the variety HAW12-156 with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety HAW12-156 with another wheat line or plant, and the creation of variants by backcrossing, mutagenesis or transformation of variety HAW12-156 are disclosed. Methods for producing other wheat varieties or breeding lines derived from wheat variety HAW12-156 and to wheat varieties or breeding lines produced by those methods are also provided.