Tooth Whitening Composition with Basic Amino Acids for Oral Health

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Solution Overview

Problem

Conventional teeth whitening products do not effectively address oral health issues such as dental caries, demineralization, hypersensitivity, and dry mouth, and may even exacerbate these conditions.

Innovation Solution

Compositions combining a dental whitening agent with basic amino acids like arginine, which are delivered to the oral cavity to inhibit caries formation, promote remineralization, reduce hypersensitivity, and improve overall oral health, while also addressing dry mouth and microbial biofilm formation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Illumination intensity

If conventional teeth whitening products are used, then teeth whitening is achieved, but oral health issues such as dental caries, demineralization, and dry mouth are not addressed or may be worsened

Engineering Contradiction:
Improveteeth whiteningVSAvoidoral health treatment capability
Core Design Contradiction:
Illumination intensityVSAdaptability or versatility

Solution Approach 1:

The whitening composition is enhanced to perform multiple functions simultaneously: whitening teeth while also treating oral health issues including dental caries, demineralization, and dry mouth through the inclusion of basic amino acids and other therapeutic ingredients

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent combines whitening agents with basic amino acids (arginine, lysine, histidine, ornithine, citrulline) and other oral care ingredients into a single composition that delivers multiple benefits: whitening, caries inhibition, remineralization, and dry mouth treatment

Inventive Principle:
Principle #5Merging (Combining)

2Adaptability or versatility

If basic amino acids are added to whitening compositions to treat oral health issues, then oral health benefits are achieved, but composition complexity increases

Engineering Contradiction:
Improveoral health treatment capabilityVSAvoidcomposition formulation
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

Basic amino acids serve multiple functions within the composition: they inhibit cariogenic bacteria, promote remineralization, raise plaque pH, and treat dry mouth, allowing a single ingredient to address multiple oral health concerns simultaneously

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The composition utilizes the pH-raising property of basic amino acids to create a more favorable oral environment, changing the chemical parameters of the oral cavity to inhibit caries and promote healing while maintaining whitening effectiveness

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compositions effectively whiten teeth, reduce dental caries, inhibit demineralization, promote remineralization, alleviate hypersensitivity, and improve oral health, while maintaining a healthy pH and reducing bacterial levels, thereby enhancing both oral and systemic health, including cardiovascular health.

Implementation Method 1

The arginolytic bacteria can use arginine and other basic amino acids to produce ammonia, thereby raising the pH of their environment

Methodology Applied
Scientific EffectMetabolism: Fermentation

Implementation Method 2

an effective amount of a dental whitening agent capable of bleaching tooth surfaces

Methodology Applied
Scientific EffectOxidation: Oxidation

Data Source

PatentUS9918918B2Compositions for tooth-whitening comprising a bleaching agent and a basic amino acid, and methods and devices for application thereof
Publication Date: 2018.03.20 COLGATE PALMOLIVE CO

AI summary

The present invention provides tooth-whitening compositions comprising a bleaching agent and a basic amino acid, together with devices for application thereof, and methods of use therefor.