Wireless Power Stent for Hyperthermia and Photodynamic Therapy
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Solution Overview
Problem
Conventional medical stents are limited in their ability to perform active anticancer therapies and are prone to detachment or blockage due to tumor proliferation, requiring invasive surgical instruments and wired connections for power and signals.
Innovation Solution
A stent using wirelessly transmitted power with an external driving apparatus that includes a power receiving portion, power storage, communication, control, and electrical stimulation components, allowing for real-time monitoring and various anticancer therapies such as hyperthermia, photodynamic therapy, and electrical stimulation, while being coated with nontoxic materials to prevent detachment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If conventional stents use only mechanical expansion force, then the stent can expand the passageway interior, but the stent cannot perform active anticancer therapy and tumors proliferate in mesh openings
Solution Approach 1:
The stent is transformed from a single-function mechanical expansion device into a multi-functional system that combines mechanical support with active anticancer therapies including hyperthermia heating, photodynamic therapy with LED light emission, and electrical stimulation, thereby preventing tumor proliferation while maintaining passageway expansion
2Reliability
If polymer coated stents are used to prevent tumor proliferation, then anticancer therapy is provided, but the stent is detached by gastrointestinal peristalsis
Solution Approach 1:
The mechanical polymer coating approach is replaced with an active therapeutic system using hyperthermia heating elements, LEDs for photodynamic therapy, and electrical stimulation components that actively prevent tumor growth without relying solely on mechanical adhesion, thereby maintaining stent position stability
3Duration of action of moving object
If wired connections are used for power and signals in anticancer therapy, then continuous therapy can be provided, but the patient suffers from pain and inconvenience
Solution Approach 1:
Wired mechanical connections for power and signal transmission are replaced with wireless communication technology, allowing continuous anticancer therapy delivery through electromagnetic signals without invasive wires, thereby eliminating patient pain and inconvenience while maintaining continuous treatment capability
Solution Approach 2:
An external driving apparatus serves as an intermediary device that wirelessly transmits power and control signals to the stent, enabling continuous therapy delivery without direct physical connections to the patient's body
4Reliability
If surgical instruments approach the tumor for therapy, then anticancer treatment is delivered, but invasive procedures cause patient pain and inconvenience
Solution Approach 1:
The need for invasive surgical instruments to approach the tumor is eliminated by extracting the therapeutic function and integrating it directly into the stent structure, which remains in place and delivers hyperthermia, photodynamic therapy, and electrical stimulation treatments without requiring repeated invasive procedures
Solution Approach 2:
The stent acts as an intermediary device implanted at the treatment site that delivers anticancer therapy locally through integrated heating elements, LEDs, and electrical stimulation components, eliminating the need for external surgical instruments to repeatedly approach the tumor
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables continuous and convenient anticancer therapy with reduced risk of stent detachment or blockage, allowing for real-time monitoring and effective delivery of therapies like hyperthermia and photodynamic therapy without the need for invasive connections.
Implementation Method 1
a power receiving portion 230 which wirelessly receives power from the exterior
Implementation Method 2
the stent is a heating stent 250, allowing heating using the power
Implementation Method 3
an LED 220 which emits light to the surroundings of the heating stent 250
Data Source
AI summary
A stent device including a stent coated with a photosensitizer, the stent including a pair of electrodes; and a circuit fixed to the stent, the circuit including a light emitting diode, a power receiving means for wirelessly receiving power from the outside, and converting the power to electric power; a second communicating means for receiving a control command from the outside; and a second control means for applying, based on the control command, the electric power to the electrodes causing an electric current to flow through the stent between the electrodes, the flow causing heating of the stent, and for controlling a temperature of the stent to provide hyperthermia therapy to a tumor, the second control means further for applying, based on the control command, the electric power to the light emitting diode to emit a predetermined wavelength of light to the photosensitizer to provide photodynamic therapy to the tumor.