Wolf-Origin Lactic Acid Bacteria for Canine Probiotics
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Solution Overview
Problem
Current probiotics for dogs, derived from human or dog-origin lactic acid bacteria, are not very effective in maintaining intestinal health and wellbeing, as they lack suitable mucus binding capacity and robustness for demanding environmental conditions.
Innovation Solution
A lactic acid bacterial strain characterized by a specific 16S RNA sequence (SEQ ID NO: 1-5) derived from the wolf intestine, which exhibits enhanced mucus binding capacity and adaptability, is used to create a biologically active culture for probiotic use, incorporated into food compositions or nutritional supplements for canines.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If probiotics are manufactured from human or dog origin lactic acid bacteria, then they are available in the market, but they do not show suitable mucus binding capacity and are not very efficient
Solution Approach 1:
The patent changes the source parameter of the probiotic bacteria from human/dog origin to wolf origin. This parameter change results in bacteria with different physiological characteristics, specifically enhanced mucus binding capacity and adaptability to canine intestinal conditions, thereby resolving the contradiction between reliability and adaptability
Solution Approach 2:
Instead of using bacteria from the same species (human for human, dog for dog), the patent inverts the approach by using bacteria from a closely related species (wolf) that has evolved under similar environmental pressures but develops different binding characteristics. This inversion strategy successfully improves mucus binding capacity while maintaining adaptability
2Reliability
If lactic acid bacteria strains are used for probiotic purposes, then they can maintain microbial flora, but current strains lack robustness for demanding environmental conditions
Solution Approach 1:
The patent changes the origin parameter of the bacterial strain from human/dog to wolf. Wolf-origin bacteria have evolved to withstand more demanding environmental conditions, providing enhanced robustness while maintaining the ability to adapt to and survive in the canine intestinal environment
Solution Approach 2:
The patent copies the successful adaptation strategy of wolf-origin bacteria, which have naturally evolved robustness for surviving in challenging environments. By using these bacteria as probiotics for dogs, the invention transfers this environmental resilience from one species to another within the same family
Data Source
AI summary
The present application relates to a lactic acid bacteria strain for probiotic use, to a biologically active culture comprising strain of at least one lactic acid bacteria, to a food composition or a nutritional supplement for canine, to a method for maintaining or improving microbial flora in gastrointestinal tract or immune system, to a method for treating or preventing diarrhea and food sensitivities. and to uses of said lactic acid bacteria.