Wound Dressing Gel Formation via Chitosan Polymer Acid Reaction

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Solution Overview

Problem

Existing wound care devices face challenges with insufficient absorption and cohesion, leading to inefficient fluid management and removal, and often require the use of hazardous materials and volatile solvents, resulting in environmental and safety concerns.

Innovation Solution

A wound care device comprising two non-gelling materials that combine to form a gel when exposed to fluids, utilizing chitosan or partially de-acetylated chitin with a non-gelling polymer and acid, which reacts to form a water-insoluble, swellable, and gellable material, eliminating the need for pre-treatment and volatile solvents, while providing enhanced absorption and cohesion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If fibre dressings are used for wound care, then the dressing can adapt to the conformation of individual wounds, but the absorption of bodily fluids is insufficient and the dressing lacks cohesion

Engineering Contradiction:
Improveadaptability to wound conformationVSAvoidabsorption capability and cohesion
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent combines two different fibrous materials (first and second fibrous materials) with distinct properties to create a composite dressing. The first material provides absorption capability while the second material provides cohesion and structural integrity, resolving the contradiction between adaptability and reliability through material composition rather than single-material properties

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent merges two separate fibrous materials into a single integrated dressing structure where the materials are combined in a specific arrangement. This merging allows the dressing to simultaneously achieve fluid absorption from the first material and cohesive strength from the second material, eliminating the need to choose between absorption and cohesion

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If gel-based dressings are used, then the dressing is cohesive and provides ideal moisture environment, but the dressing may stick to the wound site causing pain upon removal

Engineering Contradiction:
Improvecohesion and moisture managementVSAvoidadherence to wound site
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies different local qualities to different parts of the dressing - the first fibrous material has high absorption quality for moisture management while the second fibrous material has low adherence quality for pain-free removal. This spatial differentiation of material properties allows the dressing to provide cohesive moisture management without sticking to the wound site

Inventive Principle:
Principle #3Local quality

3Reliability

If chitosan fibres are treated with acid and heat to convert them into water-swelling and water-gelling form, then the fibres can absorb liquid to form a swollen coherent gel, but the process uses potentially dangerous materials and volatile solvents

Engineering Contradiction:
Improvegel-forming capabilityVSAvoidexposure to hazardous materials and environmental impact
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts the harmful acid treatment step from the traditional chitosan processing method. Instead of treating chitosan fibres with acid and heat to achieve gel-forming capability, the invention uses naturally gel-forming fibrous materials that require no chemical treatment, thereby eliminating exposure to hazardous materials and volatile solvents while maintaining the desired gel-forming property

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs materials that are inherently gel-forming and require no expensive or hazardous chemical treatment. The dressing is designed as a disposable product that achieves its function through the natural properties of the selected fibrous materials, avoiding the need for complex chemical processing and reducing environmental impact

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device effectively absorbs and encapsulates fluids, providing a cohesive dressing for easy removal, reducing environmental impact and safety risks, while being cost-effective and minimizing exposure to hazardous materials.

Implementation Method 1

capillary fluid uptake causes the fibres to swell and form a gel

Methodology Applied
Scientific EffectCapillary action: Capillary Action

Implementation Method 2

utilizing chitosan or partially de-acetylated chitin with a non-gelling polymer and acid, which reacts to form a water-insoluble, swellable, and gellable material

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Data Source

PatentUS10632224B2Wound care device
Publication Date: 2020.04.28 MEDTRADE PROD

AI summary

An absorbent wound care device includes two or more materials which individually do not gel when exposed to a fluid but do gel when brought together and exposed to a fluid. The device is particularly intended for haemostatic use and for absorbing bodily fluids being emitted from wounds and physiological target sites.