Single-Use Wrist Strap with Irreversible Fastening for Transdermal Patches
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Solution Overview
Problem
Current transdermal patches for vaccination and drug administration face challenges in ensuring sufficient skin contact time, as they can be prematurely removed, leading to incomplete treatment due to the need for prolonged application and lack of assurance that the patch remains in place.
Innovation Solution
A single-use device comprising a patch with a substance and a bracelet featuring an irreversible fastening system, such as a locking mechanism or adhesive surfaces, to securely attach the patch to the skin, preventing premature removal and ensuring prolonged contact.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If a reusable elastomer bracelet is used for transdermal application, then the device can be reused and transported easily, but the patient can prematurely remove the patch and sufficient contact time cannot be ensured
Solution Approach 1:
The bracelet is designed as a single-use disposable device rather than reusable. This eliminates the risk of premature removal since the bracelet is intended for one-time use only, ensuring that the patch remains in contact with the skin for the required duration. The disposable nature guarantees reliability of contact time while maintaining ease of transport and preservation benefits.
2Ease of operation
If a transdermal patch is applied for vaccination or drug administration, then the method avoids pain and risk of contamination, but a minimum duration of application is necessary which cannot be monitored
Solution Approach 1:
The bracelet incorporates a time-indicating element that provides visual feedback to the patient about the duration of patch application. This feedback mechanism allows the patient to monitor the contact time without requiring practitioner supervision, ensuring that the minimum necessary duration is achieved while maintaining the ease of self-administration.
3Productivity
If the stratum corneum barrier is temporarily reduced for transcutaneous administration, then high molecular weight substances can be administered systemically, but the skin barrier effectiveness is compromised during application
Solution Approach 1:
The device is designed to temporarily reduce the stratum corneum barrier effectiveness only during the necessary application period, with the time-indicating element ensuring the patch is removed after the required contact time. This preliminary controlled action allows high molecular weight substances to be absorbed systemically while limiting the duration of barrier compromise to the minimum necessary time, after which the skin barrier restores its full protective function.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device ensures that the patch remains in contact with the skin for an adequate duration, enhancing the effectiveness of transcutaneous absorption and administration of biologically active substances, including vaccines and allergens, by preventing premature removal and ensuring consistent application.
Implementation Method 1
the two fixing parts comprise mutually adhesive surfaces
Implementation Method 2
one of the two fixing parts comprises a locking member having a bore, and comprises a stud capable of being inserted irreversibly through the bore
Implementation Method 3
The penetration step is physically a passive diffusion through each structure of the integument
Implementation Method 4
an adhesive surface intended to come into contact with the skin
Data Source
Figure 1~5
AI summary
The invention relates to a device (1) for the cutaneous application of a substance (2) that comprises: a patch (3) containing said substance (2); and a single-use wrist strap (4) containing an irreversible attachment system for maintaining the substance (2) of the patch (3) against the skin of a subject.