X12T100 Hybrid Maize Breeding for Stable Trait Introgression

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Solution Overview

Problem

Existing hybrid maize development methods struggle to combine desirable traits such as disease resistance, heat and drought tolerance, and improved yield while maintaining uniformity and stability in commercial crops, especially under varying environmental conditions.

Innovation Solution

The development of the maize hybrid variety X12T100, which is produced by crossing specific inbred varieties and incorporates genetic loci for traits like male sterility, disease resistance, and altered metabolism through backcrossing and transformation, ensuring uniformity and stability through careful breeding and selection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional plant breeding is used to combine multiple desirable traits, then disease resistance and yield improvement can be achieved, but uniformity and stability of plant characteristics may be compromised

Engineering Contradiction:
Improvedisease resistanceVSAvoiduniformity of plant characteristics
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent segments the breeding process into distinct stages: developing inbred lines with specific traits, creating F1 hybrids with heterosis, and maintaining strict isolation between parental lines. This segmentation allows each component to be optimized independently while ensuring uniformity in the final hybrid product.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies preliminary action by extensively pre-characterizing and stabilizing parental inbred lines before hybridization. Multiple generations of inbreeding and selection are performed beforehand to ensure genetic uniformity and trait stability, so that the resulting F1 hybrids inherit consistent characteristics.

Inventive Principle:
Principle #10Preliminary action

2Productivity

If multiple traits are combined in a single hybrid, then agronomic quality and yield are improved, but the complexity of maintaining uniformity increases

Engineering Contradiction:
ImproveyieldVSAvoidcomplexity of trait combination
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent merges multiple desirable traits from different parental inbred lines into a single F1 hybrid. By combining disease resistance, drought tolerance, and yield characteristics in one hybrid variety, the patent achieves superior overall performance while maintaining uniformity through the hybridization process.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a universal F1 hybrid variety that performs multiple functions simultaneously: it provides disease resistance, drought tolerance, high yield, and uniform maturity. This multi-functional hybrid serves as a comprehensive solution for various agronomic challenges.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Stability of the object's composition

If inbred lines are used as parents to ensure genetic uniformity, then stable inheritance is achieved, but heterosis and yield potential are reduced

Engineering Contradiction:
Improvegenetic uniformityVSAvoidyield potential
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent applies dynamics by transitioning from static, homozygous inbred lines to dynamic, heterozygous F1 hybrids. The inbred parents provide genetic stability, while their cross produces F1 hybrids with heterotic vigor and enhanced yield potential. This dynamic transition allows the system to benefit from both uniformity and productivity.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent creates a composite genetic structure by combining two different inbred line genomes in the F1 hybrid. This composite genotype leverages the strengths of both parents, producing heterosis and superior yield while maintaining uniformity through the controlled cross.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS12484534B1Maize hybrid X12T100
Publication Date: 2025.12.02 PIONEER HI BREED INTERNATIONAL INC

AI summary

A novel maize variety designated X12T100 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X12T100 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X12T100 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X12T100, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X12T100 are provided. Methods for producing maize varieties derived from maize variety X12T100 and methods of using maize variety X12T100 are disclosed.