X-Ray Biopsy Deposition Device for In-Situ Tissue Imaging

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Solution Overview

Problem

Current methods for examining tissue samples after biopsy require the breast to be uncompressed, making it impossible to extract additional samples under identical compression conditions, leading to inefficiencies and uncertainties in the examination process.

Innovation Solution

A method and device that allow the extracted tissue sample to be transported outside the biopsy location and positioned within the x-ray radiation field, enabling x-ray-based 3D monitoring and reconstruction of slice images without needing to re-compress the breast, using an x-ray device with a biopsy unit and deposition device situated outside the extraction location.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the breast is uncompressed to examine the tissue sample with x-ray, then the tissue sample can be examined, but additional extractions under identical compression conditions cannot be performed

Engineering Contradiction:
Improvetissue sample examinationVSAvoidadditional extractions
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The examination process is segmented into two independent parts: (1) examining the extracted tissue sample in the deposition device, and (2) performing additional extractions on the compressed breast. The x-ray radiation field is divided to cover both the deposition device region and the breast region simultaneously, allowing both tasks to proceed without interfering with each other.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The tissue sample examination is moved to a different spatial dimension by placing the deposition device outside the breast compression area but within the x-ray radiation field. This allows the sample to be examined in a separate location while the breast remains in its original compressed state for potential additional extractions.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If the breast position is altered to examine the tissue sample, then the tissue sample can be examined, but examination time increases

Engineering Contradiction:
Improvetissue sample examinationVSAvoidexamination time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The examination of the tissue sample and the monitoring of the breast are merged into a single simultaneous x-ray process. The x-ray device captures images of both the deposition device containing the tissue sample and the compressed breast in one acquisition cycle, eliminating the need for separate examination steps and position changes.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The tissue sample is transported to the deposition device and positioned within the x-ray radiation field before the examination process begins. This preliminary positioning ensures that the sample is ready for immediate examination without requiring time-consuming position changes during the examination process.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If a separate x-ray device is used to examine the tissue sample, then the tissue sample can be examined without altering breast position, but device complexity increases

Engineering Contradiction:
Improveexamination conditionsVSAvoidx-ray device configuration
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The single x-ray device is designed with multi-functionality to perform both breast imaging and tissue sample examination. The x-ray radiation field and detection system are configured to cover both the compressed breast area and the deposition device area, allowing one device to replace what would traditionally require two separate devices.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The existing x-ray device serves itself by extending its examination capability to include both the breast and the extracted tissue sample. The device's radiation field and imaging system automatically adapt to capture both targets without requiring additional specialized equipment or complex configurations.

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for quick and certain examination of tissue samples without altering the breast's position, enabling identical conditions for additional extractions and reducing examination time, eliminating the need for additional x-ray devices.

Implementation Method 1

this region being in a region irradiated by x-ray radiation from an x-ray source

Methodology Applied
Scientific EffectX-Ray: X-Ray

Data Source

PatentUS9750484B2Method and device to examine a tissue sample
Publication Date: 2017.09.05 SIEMENS HEALTHINEERS AG
  • US9750484B2 patent drawing
  • US9750484B2 patent drawing

AI summary

In a method and an apparatus to exam a tissue sample, a female breast is compressed in an x-ray imaging apparatus and a biopsy procedure is conducted to extract a tissue sample from the compressed breast, with the extraction taking place using images generated by the x-ray imaging system. While the breast is still compressed, the extracted tissue sample is transported to a region outside of the extraction location that is irradiated by x-rays from the x-ray source of the imaging apparatus, and is irradiated at that region by the x-ray source in order to generate 3D data from a radiation detector that are used to reconstruct a data set of slice images from common projections of the extraction region and the tissue sample. The reconstructed slice images are then displayed.