Feed Additive Synergy Xylanase Chito-oligosaccharides Digestion

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Solution Overview

Problem

The animal feed industry faces challenges in improving animal intestinal health and feed digestion efficiency, particularly due to the absence of endogenous carbohydrases in poultry that can break down non-starch polysaccharides in diets, leading to decreased protein and energy utilization.

Innovation Solution

A feed additive comprising beta 1-4, endo-xylanase enzyme and chito-oligosaccarides (COS) is introduced, which is added to animal diets or water sources to enhance gut health and performance synergistically.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If exogenous enzymes like xylanase are added to break down non-starch polysaccharides, then nutrient digestibility and energy utilization improve, but feed costs increase

Engineering Contradiction:
Improvenutrient digestibilityVSAvoidfeed costs
Core Design Contradiction:
ProductivityVSQuantity of substance

Solution Approach 1:

The patent combines xylanase enzyme with chito-oligosaccharides (COS) in a single feed additive composition. This merging creates a synergistic effect where the enzyme breaks down non-starch polysaccharides while COS modulates gut microbiota, together improving nutrient digestibility more effectively than either component alone, thereby enhancing productivity while optimizing cost efficiency through dual functionality in one additive.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The feed additive is formulated as a composite material containing both xylanase enzyme and chito-oligosaccharides. This composite structure allows the two components to work synergistically: xylanase provides enzymatic hydrolysis of NSPs while COS influences gut microbiota composition, creating a multi-functional additive that improves feed efficiency and nutrient utilization without proportionally increasing costs.

Inventive Principle:
Principle #40Composite materials

2Reliability

If antibiotic growth promoters are used to improve animal health and performance, then growth and survival improve, but feed regulations restrict their use requiring new strategies

Engineering Contradiction:
Improveanimal healthVSAvoidfeed regulation compliance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent uses chito-oligosaccharides as an intermediary substance that modulates gut microbiota to promote animal health and performance. Instead of directly using antibiotics, COS acts as a mediator that creates a healthy gut environment by influencing microbial composition, thereby improving animal health while complying with feed regulations that restrict antibiotic use.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The feed additive changes the parameters of the gut ecosystem by introducing chito-oligosaccharides that modify microbiota composition and activity. This parameter change in the gut environment promotes animal health and performance through microbial modulation rather than direct antibiotic intervention, enabling compliance with evolving feed regulations while maintaining reliability of animal health outcomes.

Inventive Principle:
Principle #35Parameter changes

3Quantity of substance

If wheat is used as an energy source in poultry diets to reduce feed costs, then feed costs decrease, but NSPs in wheat reduce protein and energy utilization efficiency

Engineering Contradiction:
Improvefeed costsVSAvoidenergy utilization efficiency
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The patent applies segmentation by using xylanase enzyme to break down the complex non-starch polysaccharides in wheat into smaller, more manageable units. This enzymatic segmentation of NSPs improves their digestibility and allows better utilization of energy and protein from wheat-based diets, thereby maintaining low feed costs while improving energy utilization efficiency.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Chito-oligosaccharides serve as an intermediary that enhances the gut environment for better nutrient utilization from wheat. By modulating gut microbiota, COS facilitates more efficient extraction and utilization of energy and protein from wheat-containing diets, resolving the contradiction between using cost-effective wheat and maintaining high energy utilization efficiency.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination of xylanase and COS improves nutrient digestibility, increases weight gain, enhances egg quality, and promotes a healthy gut microbiome, leading to improved animal performance and intestinal health.

Implementation Method 1

poultry do not produce endogenous carbohydrases that can breakdown or hydrolyze the non-starch polysaccharides (NSPs), such as arabinoxylans

Methodology Applied
Scientific EffectHydrolysis: Hydrolysis

Implementation Method 2

the addition of xylanase enzyme into a poultry diet not only helps to reduce feed costs and animal performance, it positively influences the cecal microbiome of poultry

Methodology Applied
Scientific EffectPrebiotic effect:

Data Source

PatentUS20250120420A1Feed additive for improving animal performance, digestion and intestinal health and related methods
Publication Date: 2025.04.17 KEMIN INDUSTRIES INC
  • US20250120420A1 patent drawing
  • US20250120420A1 patent drawing
  • US20250120420A1 patent drawing

AI summary

The present invention relates to a feed additive comprising beta 1-4, endo-xylanase enzyme and chito-oligosaccarides present in an amount that provides a synergistic improvement to monogastric animal intestinal health or nutrient digestibility. Another aspect of the present invention relates to adding a composition containing beta 1-4, endo-xylanase enzyme and chito-oligosaccarides into an animal diet or water source in order to improve animal performance.