Zeolite Particle Composition Oxygen Treatment Micronization

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Solution Overview

Problem

Current zeolite compositions lack a clear correlation between micronization processes and material properties that contribute to biological effects, particularly in terms of adsorption and ion exchange capabilities, for treating conditions related to heavy metals, endotoxins, and bacterial, viral, or parasitic intoxications.

Innovation Solution

Development of zeolite particle compositions with optimized characteristics, including a specific surface area of 30.5 to 30.8 m2/g and zeta potential values less than −12.00 mV, achieved through tribo-mechanical micronization and oxygen treatment, enhancing adsorption and ion exchange properties for therapeutic and prophylactic applications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Area of stationary object

If tribo-mechanical micronization is applied to zeolite particles, then the specific surface area increases, but the correlation between micronization parameters and material properties remains unclear

Engineering Contradiction:
Improvespecific surface areaVSAvoidcorrelation between process parameters and material properties
Core Design Contradiction:
Area of stationary objectVSLoss of information

Solution Approach 1:

The patent systematically varies micronization parameters (particle size, oxygen concentration, treatment time) and measures corresponding material properties (specific surface area, adsorption capacity, ion exchange capacity, zeta potential) to establish quantitative relationships. This allows optimization of micronization conditions to achieve target material characteristics for therapeutic applications.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If zeolite particles are micronized to enhance adsorption capacity, then the surface area increases, but stability in acidic pH environments may be compromised

Engineering Contradiction:
Improveadsorption capacityVSAvoidstability in acidic pH
Core Design Contradiction:
Quantity of substanceVSStability of the object's composition

Solution Approach 1:

The patent applies oxygen treatment during or after micronization to oxidize surface groups on zeolite particles, which enhances both adsorption capacity and chemical stability in acidic environments. The oxygen exposure modifies surface chemistry to create more stable and reactive sites for toxin binding while maintaining structural integrity at low pH.

Inventive Principle:
Principle #38Strong oxidants (Accelerated oxidation)

3Manufacturing precision

If repeated micronization cycles are performed to optimize particle characteristics, then the material properties improve, but the production time and process complexity increase

Engineering Contradiction:
Improveparticle characteristics optimizationVSAvoidproduction time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The patent implements a feedback-controlled micronization process where material properties (particle size distribution, surface area, adsorption capacity) are measured after each cycle, and subsequent micronization parameters are adjusted based on this data. This allows optimization of production time by stopping the process when target characteristics are achieved, avoiding unnecessary additional cycles.

Inventive Principle:
Principle #23Feedback

4Reliability

If the zeta potential is reduced to enhance ion exchange properties, then the therapeutic effectiveness improves, but the control over zeta potential during production becomes more difficult

Engineering Contradiction:
Improvetherapeutic effectivenessVSAvoidcontrol over zeta potential
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent controls zeta potential by adjusting micronization parameters (particle size, oxygen exposure) and surface chemistry modifications. By establishing relationships between these parameters and zeta potential values, the process becomes more controllable and reproducible, allowing consistent achievement of target zeta potential ranges for optimal therapeutic performance.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The resulting zeolite compositions demonstrate improved adsorption capacities and stability in acidic pH environments, effectively treating or preventing conditions related to heavy metals, endotoxins, and parasitic intoxications, and show enhanced performance as food additives, water filters, and cosmetic ingredients.

Implementation Method 1

they are treated with a gas containing at least 95 mol-% of oxygen throughout at least one of steps (b) or (d)

Methodology Applied
Scientific EffectTribomechanical action: Friction

Implementation Method 2

Size reduction by micronization can for example be achieved by acceleration of particles so that grinding occurs by particle-to-particle impact or impact against a solid surface

Methodology Applied
Scientific EffectImpact force: Impact Force

Implementation Method 3

the particles are treated with a gas containing at least 95 mol-% of oxygen throughout at least one of steps (b) or (d)

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 4

Natural and synthetic aluminosilicates are materials with adsorption and ion-exchange capacity

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 5

Natural and synthetic aluminosilicates are materials with adsorption and ion-exchange capacity

Methodology Applied
Scientific EffectIon exchange: Ion Exchange

Data Source

PatentUS11628448B2Method and apparatus for the production of a zeolite particle composition
Publication Date: 2023.04.18 HRASCHAN JAKOB
  • US11628448B2 patent drawing
  • US11628448B2 patent drawing
  • US11628448B2 patent drawing

AI summary

The invention provides a method for the production of a zeolite particle composition which has optimized characteristics, such as enhanced adsorption and specific ion exchange properties. A method and an apparatus for producing improved zeolite particle compositions are provided, where the particles are treated with an oxygen-containing gas during micronisation. The zeolite particle compositions can be used in a method for treatment of the human or animal body by therapy and/or prophylaxis, and specifically in a method of treating or preventing conditions of the human or animal body or symptoms of these conditions that are related to heavy metals, endotoxins, exotoxins, and/or bacterial, viral or parasitic intoxications in or of the digestive system, mucosal surfaces or the skin. Also, new zeolite particle compositions can be used as food additive, as filter for purification of water, in packaging materials, or as cosmetic ingredient.