Zeolite Catalyzed Propylene Oxide Amination Selectivity

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Solution Overview

Problem

Current processes for the amination of alkylene oxides, such as propylene oxide, lack sufficient activity and selectivity towards mono- and dialkylated amine products, with excessive production of unwanted trialkylated amine byproducts.

Innovation Solution

Employing a zeolite catalyst with a framework-type structure selected from MFI, MEL, or their intergrowths, specifically comprising YO2 and optionally X2O3, to catalyze the conversion of propylene oxide to 1-amino-2-propanol and/or di(2-hydroxypropyl)amine, optimizing the catalyst's composition and structure for enhanced activity and selectivity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional catalysts (cation exchange resin, inorganic solid catalyst, silica-alumina, montmorillonite clay) are used for the amination of propylene oxide, then the reaction can proceed, but the selectivity towards mono- and dialkylated amine products is insufficient and excessive trialkylated amine byproducts are produced

Engineering Contradiction:
Improveselectivity towards mono- and dialkylated amine productsVSAvoidproduction of trialkylated amine byproducts
Core Design Contradiction:
Manufacturing precisionVSObject-generated harmful factors

Solution Approach 1:

The patent employs a zeolite catalyst with a specific porous framework structure (MFI, MEL, or their intergrowths) that provides controlled pore geometry and surface properties. The porous structure enables shape-selective catalysis where the pore dimensions and surface chemistry favor the formation of mono- and dialkylated amine products while restricting the formation of trialkylated byproducts, thereby resolving the selectivity issue with conventional catalysts

Inventive Principle:
Principle #31Porous materials

Solution Approach 2:

The zeolite catalyst represents a composite material combining specific framework structures (MFI and/or MEL) with tailored acid site distributions. This composite structure integrates the benefits of both framework types to achieve optimal selectivity for mono- and dialkylated products while minimizing trialkylated amine formation, overcoming the limitations of single-type catalysts

Inventive Principle:
Principle #40Composite materials

2Productivity

If conventional catalysts are used for the amination of propylene oxide, then the reaction proceeds, but the activity is insufficient requiring longer reaction times or higher temperatures

Engineering Contradiction:
Improvereaction activityVSAvoidreaction time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent utilizes zeolite catalysts with modified framework compositions (YO2 and optionally X2O3 where Y is tetravalent and X is trivalent) to tune the acid strength and distribution within the pores. This parameter optimization enhances the catalytic activity for propylene oxide amination, enabling complete conversion under milder conditions and reducing reaction time compared to conventional catalysts

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process achieves high selectivity towards monoisopropanol amine with minimal production of triisopropanolamine, demonstrating improved efficiency and selectivity in the amination reaction.

Implementation Method 1

ZEOLITE CATALYZED PROCESS FOR THE AMINATION OF PROPYLENE OXIDE

Methodology Applied
Scientific EffectCatalysis: Catalysis

Data Source

PatentUS20220401933A1Zeolite catalyzed process for the amination of propylene oxide
Publication Date: 2022.12.22 BASF SE

AI summary

The present invention relates to a process for the conversion of propylene oxide to 1-amino-2-propanol and/or di(2-hydroxypropyl)amine comprising (i) providing a catalyst comprising a zeolitic material comprising YO2 and optionally comprising X2O3 in its framework structure, wherein Y is a tetravalent element and X is a trivalent element, wherein the zeolitic material has a framework-type structure selected from the group consisting of MFI and/or MEL, including MEL/MFI intergrowths; (ii) providing a mixture in the liquid phase comprising propylene oxide and ammonia; (iii) contacting the catalyst provided in (i) with the mixture in the liquid phase provided in (ii) for converting propylene oxide to 1-amino-2-propanol and/or di(2-hydroxypropyl)amine.