Automated Zero-Crossing Selection for Electromechanical Wave Imaging

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Solution Overview

Problem

Current imaging techniques for cardiac conduction malfunctions, such as arrhythmias, are invasive, time-consuming, and costly, and manual selection of zero-crossing locations for electromechanical wave imaging (EWI) is particularly labor-intensive, especially with large patient populations.

Innovation Solution

An automated system using a processor configured to perform electromechanical wave imaging with a machine learning classifier, such as a Random Forest classifier, to select zero-crossing locations and generate activation maps, reducing manual intervention and increasing efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual selection of zero-crossing locations is used for EWI isochrone generation, then measurement precision can be maintained, but productivity deteriorates due to time-consuming manual analysis

Engineering Contradiction:
Improveisochrone generation accuracyVSAvoidanalysis speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent replaces the manual mechanical process of zero-crossing selection with an automated machine learning system. The Random Forest classifier automatically identifies zero-crossing locations on incremental axial strain curves, eliminating the need for manual analyst intervention while maintaining measurement precision through validated algorithms.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system enables self-service automation where the machine learning model independently performs zero-crossing detection without human intervention. The automated pipeline processes echocardiographic data, generates isochrones, and produces activation maps autonomously, significantly improving productivity while preserving accuracy through rigorous validation.

Inventive Principle:
Principle #25Self-service

2Productivity

If automated machine learning selection is used for zero-crossing locations, then productivity is improved through faster processing, but device complexity increases due to ML model implementation

Engineering Contradiction:
Improveisochrone generation speedVSAvoidsystem complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent introduces a machine learning model as an intermediary component between raw echocardiographic data and isochrone generation. This intermediary layer automates the complex task of zero-crossing detection, handling the computational complexity internally while presenting a simplified interface for clinical use and significantly improving processing speed.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If manual zero-crossing selection is performed, then measurement precision can be maintained through expert judgment, but loss of time increases due to labor-intensive analysis

Engineering Contradiction:
Improvezero-crossing detection accuracyVSAvoidanalysis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-training the Random Forest classifier on labeled datasets of zero-crossing locations. This preliminary training phase enables the model to quickly and accurately identify zero-crossings during actual analysis, eliminating time-consuming manual selection while maintaining precision through learned patterns from extensive training data.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20230363736A1Systems and methods for electromechanical wave imaging with machine learning for automated activation map generation
Publication Date: 2023.11.16 THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK
  • US20230363736A1 patent drawing
  • US20230363736A1 patent drawing
  • US20230363736A1 patent drawing

AI summary

The present subject matter relates to techniques for electromechanical wave imaging. The disclosed system can include a processor that can be configured to perform an automated selection of at least one zero-crossing location using a heuristic-based baseline and/or a machine learning classifier and generate an electromechanical wave imaging isochrone based on the automated selection.