Zinc Usnate Complexes for Skin-Friendly Antimicrobial Care

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Solution Overview

Problem

Current antimicrobial products in personal care compositions face challenges in maintaining water solubility while achieving high efficacy against pathogenic microorganisms, often requiring high concentrations that can irritate the skin and strip moisture.

Innovation Solution

The development of zinc:usnate complexes with a 1:2 molar ratio, which exhibit enhanced solubility and antibacterial activity, are incorporated into personal care compositions to address these issues, providing effective antimicrobial properties without skin irritation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional antibacterial agents are used in sufficient concentrations to control pathogenic microorganisms, then antimicrobial efficacy is improved, but skin irritation and moisture stripping worsen

Engineering Contradiction:
Improveantimicrobial efficacyVSAvoidskin irritation
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical form of the antibacterial agent from conventional compounds to zinc usnate complex, altering its physical-chemical properties to achieve both high efficacy and low irritation. The complexation of zinc with usnic acid modifies the agent's behavior on skin, maintaining antimicrobial activity while reducing harmful effects.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention uses a composite material system - zinc usnate complex - combining zinc ions with usnic acid molecules. This composite structure allows the agent to function as both an effective antimicrobial and a skin-friendly substance, resolving the contradiction between efficacy and irritation.

Inventive Principle:
Principle #40Composite materials

2Ease of operation

If water solubility of antimicrobial agents is improved, then ease of formulation and delivery is improved, but antimicrobial efficacy may worsen

Engineering Contradiction:
Improvewater solubilityVSAvoidantimicrobial efficacy
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent modifies the solubility parameter by creating zinc usnate complex, which has different solubility characteristics compared to conventional antibacterial agents. The complex maintains adequate water solubility for formulation while preserving the antimicrobial active components at effective concentrations.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP3654927B1Personal care compositions comprising zinc:usnic acid complexes and methods of use
Publication Date: 2023.09.06 COLGATE PALMOLIVE CO
  • EP3654927B1 patent drawingFigure 1
  • EP3654927B1 patent drawingFigure 2
  • EP3654927B1 patent drawingFigure 3

AI summary

Disclosed herein are personal care compositions comprising Zn:usnate complexes having a 1:2 zinc to usnate molar ratio. Methods of making and using the compositions are also provided. The personal care compositions may include a cleansing component and an antibacterial component, wherein the antibacterial component comprises Zn:usnate complexes having a 1:2 zinc to usnate molar ratio.