High-pressure immunohistochemical system and method

By using a flip mechanism in the immunohistochemistry system to turn the sample carrier in the reagent container, the problems of reagent loss, evaporation and non-specific reactions were solved, and more efficient and accurate immunohistochemistry experiments were achieved.

CN119667138APending Publication Date: 2025-03-21FUZHOU UNIV +1
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Patent Information

Application Number
CN202510165495.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Priority Date
2024-12-30
Filing Date
2025-02-14
Publication Date
2025-03-21

AI Technical Summary

Technical Problem

During the reagent addition and incubation process of existing immunohistochemistry systems, the exposure of sample carrier to air causes reagent loss and evaporation, and is prone to non-specific reactions with substances in the air, affecting the accuracy of detection.

Method used

A high-pressure immunohistochemistry system was designed, and the sample carrier was turned upside down in a container containing reagents to prevent reagent loss and evaporation and reduce non-specific reactions. The system includes a thermal repair reaction device, an incubation device and a flip mechanism. Through the cooperation of these devices, the precise positioning and covering liquid addition of the sample carrier at different operating stages is achieved.

Benefits of technology

It effectively prevents reagent loss and evaporation, reduces non-specific reactions, improves the efficiency and accuracy of the incubation process, and significantly improves the quality and efficiency of immunohistochemistry experiments.

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Abstract

The invention relates to a biological reaction device, in particular to a high-pressure immunohistochemical system and method. The invention provides a high-pressure immunohistochemical system. The high-pressure immunohistochemical system comprises a thermal repair reaction device, an incubation device and a turnover mechanism, the thermal repair reaction device, the incubation device and the turnover mechanism are arranged; sample carriers can be accommodated in the thermal repair reaction device and the incubation device; and the overturning mechanism is used for overturning or / and moving the sample carrier. According to the method disclosed by the invention, the sample carrier is accurately positioned in different operation stages through the cooperation of the thermal repair reaction device, the incubation device and the turnover mechanism. And the overturning mechanism can ensure that the sample is covered in the liquid adding and incubation links, so that the loss and evaporation of the reagent are reduced.
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