Active focusing module of pathological section scanning equipment based on weak measurement

Through the active focus module of the pathological section scanning device based on weak measurement, the Wollaston prism and polarization optical elements decompose the beam, and the precise measurement of slight height changes on the surface of the pathological section is achieved, solving the problem of insufficient accuracy of traditional focusing technology and improving the imaging quality of pathological diagnosis.

CN120369632AActive Publication Date: 2025-07-25SHENZHEN SHENGQIANG TECH
4 Cites 0 Cited by

Patent Information

Application Number
CN202510855122.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-06-25
Publication Date
2025-07-25
Estimated Expiration
2045-06-25

AI Technical Summary

Technical Problem

The existing active focus technology of pathological section scanning equipment is insufficient in handling slight height changes, making it difficult to meet the needs of high-precision pathological diagnosis, and is susceptible to differences in tissue optical characteristics and environmental interference.

Method used

The active focus module of the pathological slice scanning device based on weak measurement is used to decompose the incident light into two orthogonal polarized light using Wollaston prism and polarization optical elements. The center of gravity offset of the bimodal spectrum is analyzed by a spectrometer to calculate the fluctuation and change of the sample surface ups and downs to achieve non-contact high sensitivity measurement.

Benefits of technology

It realizes accurate measurement of slight height changes on the sample surface, improves focus accuracy and imaging clarity, is suitable for living tissues or fragile samples, has strong anti-environmental interference ability, and meets the needs of high-speed scanning.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention discloses an active focusing module of pathological section scanning equipment based on weak measurement, which is characterized in that incident light in a preset polarization state is emitted by a light source and is divided into first reference light and detection light through a polarization splitting prism and a Wollaston prism; the first reference light is reflected by the lower surface of the cover glass to form second reference light, the detection light is reflected by the surface of the sample to form sample light, and the second reference light and the sample light enter the Wollaston prism again for weak coupling and beam combination to form emergent light; the emergent light is received by a spectrometer after phase modulation and polarization selection, and the center-of-gravity shift of the double-peak spectrum can reflect the fluctuation height change of the surface of the sample, so that high-precision focusing is realized. According to the technology, the weak measurement principle is utilized, tiny physical quantity changes are converted into observable spectrum shift, the theoretical sensitivity reaches the picometer level, the focusing accuracy is remarkably improved, and the definition of a scanned image is guaranteed.
Need to check novelty before this filing date? Find Prior Art