Composite yolk immunoglobulin antibody toothpaste and preparation method thereof

By adding complex egg yolk immunoglobulin antibodies targeting periodontal pathogens into toothpaste, the problems of bacterial imbalance and drug resistance in existing antibiotic therapies are solved, and precise antibacterial and repair effects on periodontitis are achieved.

CN120771072APending Publication Date: 2025-10-14SHANGHAI MEIJIAJING DAILY CHEM CO LTD
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Patent Information

Application Number
CN202510568314.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-04-30
Publication Date
2025-10-14

AI Technical Summary

Technical Problem

Existing antibiotic adjuvant therapies in the treatment of periodontitis have the risk of bacterial imbalance and drug resistance caused by broad-spectrum antibacterial effects, making it difficult to achieve precise treatment.

Method used

A composite egg yolk immunoglobulin antibody toothpaste has been developed, which contains specific egg yolk immunoglobulin antibodies that target Porphyromonas gingivalis, Fusobacterium nucleatum and Prevotella intermedia, and can inhibit bacteria and prevent oral inflammation through brushing.

Benefits of technology

It effectively inhibits periodontal pathogens, reduces oral inflammation, promotes gum repair, and has a passive immune effect with strong targeting and high safety.

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Abstract

The invention discloses composite yolk immunoglobulin antibody toothpaste and a preparation method thereof, and the toothpaste comprises the following components in percentage by mass: 0.01-1.0% of yolk immunoglobulin; 10-70% of a humectant; 0.01%-0.5% of an acid-base buffer agent; 0.01%-0.5% of a taste improver; 0.1%-3% of a thickening agent; 5-50% of a friction agent; 0.1-5% of a foaming agent; 0.01%-0.5% of an appearance improver; 0.1 to 2.0 percent of essence; and the balance of water. Wherein the egg yolk immune globulin is a composite specific egg yolk antibody for resisting porphyromonas gingivalis, fusobacterium nucleatum and prevotella intermedia. Starting from three key pathogenic bacteria causing periodontal diseases, the egg yolk composite antibody resisting porphyromonas gingivalis and having specificity of fusobacterium nucleatum and prevotella intermedius is added into a toothpaste formula, and the effects of inhibiting bacteria, preventing and relieving oral inflammation, repairing gingiva and the like are achieved in a tooth brushing mode.
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