Method for producing dairy products

JP2024539915A5Pending Publication Date: 2025-10-31SOCIETE DES PRODUITS NESTLE SA
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Patent Information

Application Number
JP2024523887
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2021-10-27
Filing Date
2022-10-27
Publication Date
2025-10-31

AI Technical Summary

Technical Problem

Current methods for producing human milk are limited by the availability of human donors, regulatory constraints, and the inability of existing infant formulas to replicate the complex components of human breast milk, making it difficult to provide a sustainable and customized milk substitute.

Method used

A method involving the culture and differentiation of mammalian induced pluripotent stem cells (miPSCs) in retinoic acid (RA) to generate embryoid bodies (EBs), which are then grown to produce mammary gland cells and secrete mammalian milk-like products, including human milk-like products, tailored to specific nutritional needs.

Benefits of technology

This method enables the production of human milk-like products with similar components to breast milk, offering a sustainable and customizable alternative that can be used as a substitute or supplement, addressing the limitations of current infant formulas and donor milk availability.

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Abstract

A method for producing mammary cells, and a method for producing a mammalian milk-like product, such as a human milk-like product, comprising generating lactocytes derived from mammalian induced pluripotent stem cells (miPSCs), such as human induced pluripotent stem cells (hiPSCs), and expressing the mammalian milk-like product, such as the human milk-like product, from the lactocytes.
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