Devices and methods for multi-scope bronchoscopy

Abstract

This document provides devices and methods for a multi-port adapter including a main body defining a central cavity and a main opening to the central cavity that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask, a first receiver tube extending from the main body, a second receiver tube extending from the main body, wherein the first and the second receiver tube are sized to slidably receive a second bronchoscope. A ventilator connection tube extends from the main body, and an auxiliary tube extends from the ventilator connection tube.

Description

[0001] DEVICES AND METHODS FOR MULTI-SCOPE BRONCHOSCOPY

[0002] CROSS-REFERENCE TO RELATED APPLICATIONS

[0003] This application claims the benefit of U.S. Provisional Application Serial No. 63 / 547,648 filed November 7, 2023. The disclosure of the prior application is considered part of (and is incorporated by reference in) the disclosure of this application.

[0004] TECHNICAL FIELD

[0005] This document relates to devices and methods for multi-scope bronchoscopy. For example, this document relates to devices and methods of dual bronchoscopy using an adapter including multiple ports to accommodate more than one bronchoscope during a bronchoscopy procedure.

[0006] BACKGROUND INFORMATION

[0007] Bronchoscopes are medical devices used to visually examine the interior of a patient's airway and perform various procedures, such as biopsies and foreign body removal. Forms of bronchoscopes include rigid bronchoscopes, offering a stable and larger passage for instruments, and flexible bronchoscopes, which provide access to more distal parts of the bronchial tree.

[0008] SUMMARY

[0009] This disclosure provides devices and methods for multi-scope bronchoscopy procedures. The limitation of conventional bronchoscopic interventions to a single bronchoscopist is due to the lack of a multi-scope interface that would enable the simultaneous use of more than one scope (e.g., bronchoscopes). This constraint is noticeable in complex interventional pulmonology cases or during bronchoscopic technique training, where the addition of another bronchoscope is beneficial.

[0010] The multi-port adapters described in this disclosure facilitate multi-scope bronchoscopy procedures and optionally, continuous CO2 monitoring. The improved adapter (multi-port adapter) aims to address a significant problem in the field of bronchoscopy interventions that remains unmet by current technology. While existing technology can successfully facilitate the use of a single bronchoscope for intervention procedures, it falls short of facilitating more complex procedures that involve the insertion of more than one instrument into the airway of a subject (e.g., a human or animal).

[0011] Examples of instruments that can be used during bronchoscopic interventions include, but are not limited to, biopsy forceps for tissue sampling, brushes for collecting cells, and needles for tissue aspiration or medication injection. In some cases, balloons are used to dilate narrowed airways, while stents help to keep collapsed airways open. Snares can be employed for foreign body removal, and catheters are utilized for suctioning or administering drugs. Cryoprobes assist in freezing and removing tissue, and laser fibers are used for cutting or tumor reduction. Argon plasma coagulation probes help to stop bleeding or destroy tumors, and electrocautery probes are used for cauterizing tissue. For cancer treatments, photodynamic therapy fibers are used. Endobronchial ultrasound probes allow visualization of structures adjacent to the airways, and various foreign body retrieval tools, including baskets and magnets, are used for extracting inhaled objects. The selection of devices is determined by the procedure requirements and the patient's specific needs.

[0012] Embodiments of the devices and methods described in this disclosure provide one or more of the following advantages. First, the multi-port adapter described herein integrates multiple receiver tubes that define respective ports, a ventilator tube defining a respective ventilation port, and a main opening configured to couple with a proximal end of an endotracheal tube or laryngeal mask connection, facilitating safer and more efficient pulmonology procedures and bronchoscopic techniques. This multi-port adapter can be particularly useful in airway stent placement for direct visualization, enabling simultaneous viewing and manipulation of instruments. It also aids in quicker, safer foreign body removal by offering an additional perspective or instrument pathway. For managing airway bleeding, it provides vital access for both viewing and intervention. Transbronchi al biopsies, such as cryobiopsies, enable concurrent biopsy and airway management. The improved multi-port adapter is also useful in tumor debulking and airway fistula management, allowing simultaneous tumor removal or fistula closure while maintaining airway integrity. Second, the multi-port adapter's capability for multi-scope bronchoscopy procedures benefits complex procedures needing multiple visual angles and is advantageous in training scenarios where both an instructor and a trainee can concurrently view the airway.

[0013] Third, the multi-port adapter decreases reliance on rigid bronchoscopy for complex procedures by allowing the use of multiple instruments (e.g., multiple flexible bronchoscopes). This expands the visual field and access, attributes usually linked with rigid bronchoscopes. Consequently, it enables the management of complex procedures using flexible techniques, reducing patient risk and the need for general anesthesia. This feature is also valuable in training and collaborative situations, allowing less experienced clinicians to benefit from the guidance of more seasoned practitioners.

[0014] Fourth, the multi-port adapter significantly reduces bronchoscopy procedure time. Accommodating multiple instruments (e.g., flexible bronchoscopes) enables more effective airway navigation and examination. This is particularly effective in complex procedures, where traditional single-scope techniques require multiple insertions. Fifth, the adapter enhances bronchoscopic procedures by optionally enabling continuous CO2 monitoring for patient safety. Efficient CO2 sampling without disrupting bronchoscopy procedures and timely detection of hypoventilation or apnea during sedation or anesthesia are safety benefits of this feature.

[0015] One aspect of this document features devices and methods, and processes for multiscope bronchoscopy procedures. In some example embodiments, devices can include, or consist essentially of, a multi-port adapter, comprising a main body defining a central cavity and a main opening to the central cavity that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask, a first receiver tube extending from the main body and defining a first receiver port and a first lumen extending between the first receiver port and the central cavity, the first receiver port and first lumen sized to slidably receive a first bronchoscope, a second receiver tube extending from the main body and defining a second receiver port and a second lumen extending between the second receiver port and the central cavity, the second receiver port and second lumen sized to slidably receive a second bronchoscope, a ventilator connection tube extending from the main body and defining a third port and a third lumen extending between the third port and the central cavity, and an auxiliary tube extending from the ventilator connection tube and defining a fourth port and a fourth lumen extending between the fourth port and the third lumen.

[0016] In some embodiments, the central axes of the first receiver tube and the second receiver tube define an angle of between 30 and 40 degrees. In some embodiments, a diameter of the first receiver port and a diameter of the second receiver port is about 4 inches to about 10 inches. In some embodiments, a diameter of the first receiver tube and a diameter of the second receiver tube are about the same. In some embodiments, a diameter of the first receiver tube is different from a diameter of the second receiver tube. In some embodiments, the first receiver tube, the second receiver tube, the auxiliary tube, and the ventilator connection tube are fluidly connected to the central cavity of the main body. In some embodiments, the device further comprises a swivel mechanism between a base at a distal end of the main body and an apex of the main body.

[0017] In some embodiments, the proximal end of the endotracheal tube is about 2 inches to about 12 inches. In some embodiments, the ventilator connection tube is sized to couple to a ventilator circuit. In some embodiments, the fourth port of the auxiliary tube is configured to couple with a proximal end of a CO2 monitoring device.

[0018] In another example embodiment, devices can include, or consist essentially of a multi-port adapter, comprising a main body defining a central cavity, wherein the main body comprises a base defining a main opening to the central cavity that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask, an apex that is configured for dynamic movement, and a swivel mechanism between the base and the apex of the main body, wherein the swivel mechanism is configured to enable dynamic movement of the apex and stability of the base, and a first receiver tube extending from the apex of the main body and defining a first receiver port and a first lumen extending between the first receiver port and the central cavity, the first receiver port and first lumen sized to slidably receive a bronchoscope, a second receiver tube extending from the apex of the main body and defining a second receiver port and a second lumen extending between the second receiver port and the central cavity, the second receiver port and second lumen sized to slidably receive a bronchoscope, a ventilator connection tube extending from the apex of the main body and defining a third port and a third lumen extending between the third port and the central cavity, and an auxiliary tube extending from the ventilator connection tube and defining a fourth port and a fourth lumen extending between the fourth port and the third lumen.

[0019] In some embodiments, a central axes of the first receiver tube and the second receiver tube define an angle of between 30 and 40 degrees. In some embodiments, a diameter of the first receiver port and a diameter of the second receiver port is about 4 inches to about 10 inches. In some embodiments, a diameter of the first receiver tube and a diameter of the second receiver tube are about the same. In some embodiments, a diameter of the first receiver tube is different from a diameter of the second receiver tube. In some embodiments, the proximal end of the endotracheal tube is about 2 inches to about 12 inches. In some embodiments, the ventilator connection tube is sized to couple to a ventilator circuit. In some embodiments, the fourth port of the auxiliary tube is configured to couple with a proximal end of a CO2 monitoring device. In some embodiments, the auxiliary tube is configured to continually monitor CO2.

[0020] In another example embodiment, a method for using a multi-port adapter, comprises coupling a proximal end of an endotracheal tube or a laryngeal mask to a main body of the multi-port adapter comprising a first receiver tube, a second receiver tube, a ventilator connection tube, and an auxiliary tube, coupling a ventilator circuit to the ventilator connection tube of the multi-port adapter, coupling a CO2 monitoring device to the auxiliary tube, inserting a first bronchoscope into the first receiver tube of the multi-port adapter, and inserting a second bronchoscope into a second receiver port of the multi-port adapter, wherein the multi-port adapter is a fluidly connected closed system.

[0021] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Although methods and materials similar or equivalent to those described herein can be used to practice the invention, suitable methods and materials are described below. All publications, patent applications, patents, and other references mentioned herein are incorporated by reference in their entirety. In case of conflict, the present specification, including definitions, will control. In addition, the materials, methods, and examples are illustrative only and not intended to be limiting. The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the invention will be apparent from the description and drawings, and from the claims.

[0022] DESCRIPTION OF THE DRAWINGS

[0023] FIG. 1 depicts a perspective view of an example multi-port adapter according to some embodiments of this disclosure.

[0024] FIG. 2 depicts a top-down view of an example multi-port adapter according to some embodiments of this disclosure.

[0025] FIG. 3 depicts a cross-section view of an example multi-port adapter according to some embodiments of this disclosure.

[0026] FIG. 4 depicts a side view of the example multi-port adapter of FIG. 3 according to some embodiments of this disclosure.

[0027] FIG. 5 depicts a front view of an example multi-port adapter according to some embodiments of this disclosure.

[0028] FIG. 6 depicts another cross-section view of the example multi-port adapter of FIG. 5 according to some embodiments of this disclosure.

[0029] FIG. 7 depicts an example method of using the multi-port adapter according to some embodiments of this disclosure.

[0030] DETAILED DESCRIPTION

[0031] FIG. 1 depicts a perspective view of an example multi-port adapter according to some embodiments of this disclosure. The multi-port adapter 100 includes a first receiver tube 102a, a second receiver tube 102b, a ventilator connection tube 104, an auxiliary tube 106, and a main body 108. In some embodiments, the main body 108 includes a swivel mechanism 110 positioned between a base 116 and an apex 114.

[0032] The main body 108 defines an interior portion configured to fluidly connect the first receiver tube 102a, the second receiver tube 102b, the ventilator connection tube 104, and the auxiliary tube 106 with efficient fluid flow (e.g., airflow) and accessibility for instruments. The interior of the main body 108 includes two bronchoscopic channels corresponding to the first receiver tube 102a and the second receiver tube 102b. The first receiver tube 102a extends from the main body 108 and defines a first receiver port 103a and a first lumen (shown in greater detail in FIG. 3) extending between the first receiver port 103a and the central cavity. The first receiver port 103a and first lumen (e.g., a bronchoscopic channel) are sized to slidably receive an instrument (e.g., a bronchoscope). The second receiver tube 102b extends from the main body 108 and defines a second receiver port 103b and a second lumen (shown in greater detail in FIG. 3) extending between the second receiver port 103b and the central cavity. The second receiver port 103b and second lumen (e.g., a bronchoscopic channel) are sized to slidably receive an instrument (e.g., a bronchoscope).

[0033] The bronchoscopic channels formed by the first lumen and the second lumen are the passages through which the instruments are inserted via the respective first receiver tube 102a and the second receiver tube 102b. In some embodiments, they are sufficiently wide and are sized to accommodate various instruments. They are also configured to provide a snug fit at the respective ports 103a and 103b to maintain an airtight seal between the interior of the main body 108 and the exterior atmosphere. In some embodiments, the bronchoscopic channels and / or the interior portion of the main body 108 has a protective lining to prevent damage to the bronchoscopic scopes and to ensure smooth insertion and manipulation.

[0034] The ventilator connection tube 104 extends from the main body 108 and defines a third port 105 and a third lumen (e.g., a ventilator channel) extending between the third port 105 and the central cavity of the main body 108. In some embodiments, the ventilator connection tube 104 is coupled to the main body 108 and positioned on the opposite side from the first receiver tube 102a and / or the second receiver tube 102b. The ventilator connection tube 104 connects to a ventilator system (e.g., a ventilator circuit), allowing for the controlled delivery of gases through the central cavity of the main body 108. The third lumen (e.g., a ventilator channel) allows for the continuous delivery of anesthetic gases or oxygen and the maintenance of ventilation during a bronchoscopic procedure.

[0035] The main body 108 includes a main opening to the central cavity (depicted in FIG. 3) at the base 116 that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask. The multi-port adapter 100 connects to the endotracheal tube or laryngeal mask at the distal end (i.e., the base) of the main body 108, providing an airtight seal. This connection can be configured to be robust to prevent disconnections or leaks, which could compromise the patient's ventilation.

[0036] In some embodiments, the main body 108 monitors fluids (e.g., gasses) via an auxiliary tube 106. The auxiliary tube 106 extends from the ventilator connection tube 104 and defines a fourth port 107 and a fourth lumen (depicted in greater detail in connection with FIG. 6) extending between the fourth port 107 and the third lumen (e.g., a ventilator channel).

[0037] In some embodiments, the auxiliary tube 106 monitors CO2. In such embodiments, the multi-port adapter 100 is connected to a CO2 monitoring device to continuously assess the patient's respiratory status via the auxiliary tube 106. The placement of the auxiliary tube 106 can be such that it doesn't interfere with respective instruments or other instruments used in the respective first receiver tube 102a, second receiver tube 102b, or the ventilator connection tube 104. In some embodiments, the auxiliary tube 106 can be located adjacent to the first receiver tube 102a or the second receiver tube 102b.

[0038] In some embodiments, the diameter of the first receiver tube 102a and the second receiver tube 102b of the multi-port adapter 100, can vary depending on the design, intended use, and size of the patient’s anatomy. However, they generally accommodate the outer diameter of standard instruments (e.g., bronchoscopes) and have airtight seals at the respective defined ports 103a and 103b. For example, the first receiver tube 102a and the second receiver tube 102b on a multi-port adapter 100 are larger in diameter than the largest instrument intended to be used with it. In such cases, the diameter of each receiver tube 102a and 102b in the multi-port adapter 100 is about 0.2 inches to about 1 inch to ensure a snug fit and maintain an airtight seal around the bronchoscope.

[0039] The first receiver tube 102a and the second receiver tube 102b are configured to be in close proximity to each other and strategically placed to avoid interference during their simultaneous use of respective instruments. Internally, the common area within the main body 108 is the shared pathway for fluid exchange, while the individual first receiver tube 102a and second receiver tube 102b maintain their distinct channels and connections for their respective instruments during a procedure. The example configuration of the first receiver tube 102a and the second receiver tube 102b depicted in FIG. 1 is an example of efficient utilization of space within the multi-port adapter 100 while maintaining the integrity of each function — ventilation, instrument insertion, and CO2 monitoring.

[0040] In some embodiments, the multi-port adapter 100 includes a swivel mechanism 110. The swivel mechanism 110 is configured to facilitate and accommodate the dynamic movement of one or more instruments during a procedure. The swivel mechanism 110 of the multi-port adapter 100 can allow the simultaneous use of one or more instruments inserted through respective receiver tubes 102a and 102b to be maneuvered with flexibility and range of motion, reducing the risk of dislodging the endotracheal tube or causing trauma to the airway of the subject.

[0041] The swivel mechanism 110 can allow rotation of the multi-port adapter 100 as indicated by arrow 112. For example, the swivel mechanism 110 of the multi-port adapter 100 allows for the rotation (see arrow 112) of the apex portion 114 of the main body 108 while keeping the base 116 of the main body stationary. In this way, one or more instruments (e g., one or more bronchoscopes) inserted into the multi-port adapter 100 can be turned or maneuvered via the apex 114 without twisting the multi-port adapter 100 or the connected tubes, allowing for greater flexibility and control during a procedure. In this configuration, the swivel mechanism’s 110 location provides that movement of multiple instruments, including rotation or angling, does not exert undue stress on the laryngeal mask or the endotracheal tube, minimizing the risk of dislodging the tube or causing trauma to the patient. This configuration effectively decouples the movements of the instruments (e.g., multiple bronchoscopes) inserted into the respective receiver tubes 102a and 102b and the connected breathing circuit, providing flexibility and safety during a bronchoscopy procedure.

[0042] FIG. 2 depicts a top-down view of an example multi-port adapter according to some embodiments of this disclosure. The features described in connection with FIG. 2 share the same features and functionality as FIG. 1 . For example, the multi-port adapter 200 includes a main body 208 that shares features with multi-port adapter 100 and main body 108. FIG. 2 depicts a top-down view of a multi-port adapter 200 that includes a first receiver tube 202a defining a first receiver port 203a, a second receiver tube 202b defining a second receiver port 203b, a main body 208, and a ventilator tube 204 defining a third port 205. The top- down view of FIG. 2 shows the layout and spatial arrangement of the first receiver tube 202a and second receiver tube 202b, the ventilator tube 204, and the main body 208. The top-down perspective provides an example of the relative positioning of the first receiver tube 202a and the second receiver tube 202b and how they are oriented in relation to one another.

[0043] From the viewpoint of FIG. 2, the first receiver port 103a and the second receiver port 103b of the first receiver tube 202a and the second receiver tube 202b respectively show that there is unobstructed access for an instrument in each receiver tube 202a and 202b. The proximity and angle of the first receiver tube 202a and the second receiver tube 202b respective to each other show how the multi-port adapter 200 facilitates the use of two instruments simultaneously without interference.

[0044] In some embodiments, the ventilator tube 204 is designed with an angled placement. This angle is strategic, as it can allow for the effective manipulation of instruments inserted into the first receiver tube 202a and second receiver tube 202b. This design ensures that healthcare workers can operate the instruments during a procedure without hindering the function of a ventilator connected to the ventilator tube 204 at its distal end (i.e., the third port 205). The positioning and angling of the ventilator tube 204 relative to the first receiver tube 202a and second receiver tube 202b facilitate smooth and independent usage of these instruments, thereby avoiding interference between instrument manipulation and ventilatory support.

[0045] FIG. 3 depicts a cross-section side view of an example multi-port adapter according to some embodiments of this disclosure. The features described in connection with FIG. 3 share the same features and functionality as FIGS. 1 and 2. For example, the multi-port adapter 300 includes a main body 308 that shares the same features with multi-port adapters 100 and 200 including a main body 108 and 208 respectively. FIG. 3 depicts a cross-section side view of multi-port adapter 300 including a main body 308 defining a central cavity 324 and a main opening 322 to the central cavity 324 that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask. A first receiver tube 302a extends from the main body 308 and defines a first receiver port 303a and a first lumen 320a extending between the first receiver port 303a and the central cavity 324. The first receiver port 303a and first lumen 320a are sized to slidably receive an instrument (e.g., a bronchoscope).

[0046] A second receiver tube 302b extends from the main body 308 and defines a second receiver port 303b and a second lumen 320b extending between the second receiver port 303b and the central cavity 324, the second receiver port 303b and second lumen 320b are sized to slidably receive another instrument (e.g., a bronchoscope).

[0047] The embodiment of FIG. 3 shows the angle of the first receiver tube 302a relative to the second receiver tube 302b. In some embodiments, the central axis of the first receiver tube 302a and the second receiver tube 302b relative to the central axis of the main body 308 is about 10° to about 25°. In some embodiments, the angle defined between the central axis of the first receiver tube 302a relative to the central axis of the main body 308 (identified as section B-B) is about 20°. For example, FIG. 3 depicts an angle of the first receiver tube 302a at 17° relative to the central axis of the main body 308 identified as section B-B. The central axes of the first receiver tube 302a and the second receiver tube 302b can define an angle of between 30 and 40°. The angle between the first receiver tube 302a and the second receiver tube 302b in the multi-port adapter 300 is important for maintaining airflow efficiency and allowing the maneuverability of two instruments (one in each of the first receiver tube 302a and 302b) used simultaneously.

[0048] FIG. 3 depicts an example of the dimensions from the main opening 322 of the main body 308 to the distal end of the first receiver tube 302a. In some embodiments, the distance from the main opening 322 of the main body 308 to the outer distal end of the first receiver tube 302a is about 1.2 inches to about 2 inches. In some embodiments, the distance from the main opening 322 of the main body 308 to the outer distal end of the first receiver tube 302a is about 1.5 inches. For example, FIG. 3 depicts the distance from the main opening 322 of the main body 308 to the outer distal end of the first receiver tube 302a is about 1.7 inches.

[0049] In some embodiments, the distance from the central axis (section B-B) of the central cavity 324 to the outer distal end of the second receiver tube 302b is about 0.3 inches to about 1 inch. In some embodiments, the distance from the central axis of the central cavity 324 to the outer distal end of the second receiver tube 302b is 0.6 inches. For example, FIG. 3 depicts the distance from the central axis of the central cavity 324 to the outer distal end of the second receiver tube 302b is about 0.8 inches.

[0050] FIG. 4 depicts a side view of an example multi-port adapter according to some embodiments of this disclosure. The features described in connection with FIG. 4 share the same features and functionality as FIGS. 1, 2, and 3. For example, the multi-port adapter 400 includes a main body 408 that shares the same features with multi-port adapters 100, 200, and 300 including a main body 108, 208, and 308 respectively. Multi-port adapter 400 includes a main body 408, a ventilator tube 404, an auxiliary tube 406 extending from the ventilator tube 404, and a second receiver tube 402b. The side view of FIG. 4 shows an example multi-port adapter 400 with example dimensions and example angles of the second receiver tube 402b. The angle formed between the central axis of the first receiver tube (obscured) and the second receiver tube 402b (the B-B line) and the central axis of the main body 408 is shown in FIG. 4. In some embodiments, the angle of the ‘section B-B’ line relative to the central axis of the main body 408 is about 5° to about 15°. For example, FIG. 4 shows an embodiment of the angle of the ‘section B-B’ line relative to the central axis of the main body 408 is about 10°. In such embodiments, the angle helps optimize the entry angle of the instruments through the second receiver tube 402b and the first receiver tube (visible in FIG. 3 as 302a), making insertion and navigation within the patient’s airway more controlled. It reduces the resistance against the bronchoscopes as they move, enhancing ease of use. Additionally, this angling away from the central axis of the main body 408 can help in aligning the instruments more effectively with the airway anatomy, improving access to various lung regions and facilitating better visualization and intervention during multi-scope procedures.

[0051] FIG. 4 further depicts some example dimensions. In some embodiments, the distance from the distal end of the auxiliary tube 406 and the main body 408 can be about 0.4 inches to about 1.2 inches. In some embodiments, the distance between the distal end of the auxiliary tube 406 and the main body 408 is about 1 inch. For example, the distance between the distal end of the auxiliary tube 406 and the main body 408 is about 0.8 inches as depicted in the example of FIG. 4. In some embodiments, the distance from the distal end of the ventilator tube 404 and the main body 408 can be about 0.5 inches to about 1.5 inches. In some embodiments, the distance between the distal end of the ventilator tube 404 and the main body 408 is about 0.8 inches. For example, the distance from the distal end of the ventilator tube 404 and the main body 408 is about 1 inch as depicted in the example of FIG. 4.

[0052] In some embodiments, the distance from the distal end of the ventilator tube 404 and the posterior distal end of the second receiver tube 402b can be about 1.5 inches to about 2.5 inches. In some embodiments, the distance from the distal end of the ventilator tube 404 and the posterior distal end of the second receiver tube 402b is about 1.8 to about 2.2 inches. For example, the distance from the distal end of the ventilator tube 404 and the posterior distal end of the second receiver tube 402b is about 2 inches as depicted in the example of FIG. 4.

[0053] FIG. 5 depicts a front view of an example multi-port adapter according to some embodiments of this disclosure. The features described in connection with FIG. 5 share the same features and functionality as FIGS. 1, 2, 3, and 4. For example, the multi-port adapter 500 includes a main body 508 that shares the same features with multi-port adapters 100, 200, 300, and 400 including a main body 108, 208, 308, and 408 respectively. Multi-port adapter 500 includes a main body 508, an auxiliary tube 506, a first receiver tube 502a, a second receiver tube 502b, a ventilation connection tube 504, and a demarcated axis A-A. The view of FIG .5 shows the multi-port adapter 500, depicting the angled positioning of the auxiliary tube 506 and the ventilation connection tube 504.

[0054] In the example embodiment of FIG. 5, the auxiliary tube 506 is angled and pointed toward the distal end of the main body 508 and the ventilation connection tube 504 oppositely (e.g., directed away from the proximal end of the main body 508). This configuration serves several advantages. For example, the angled design of the multi-port adapter's 500 auxiliary tube 506 and ventilation connection tube 504 directs the auxiliary tube 506 and ventilation connection tube 504 in opposite directions. In this example, airflow from ventilation connection tube 504 is prevented from disrupting operations through auxiliary tube 506, providing a clear path for both ventilation and other procedures monitoring (e.g., CO2 monitoring). This configuration provides the versatility of the multiport adapter 500 because it increases compatibility with different medical device manufacturers, facilitating the optimal placement and maneuverability of bronchoscopes, ventilation equipment, and other tools. This configuration also enhances accessibility and visibility within the patient's airway.

[0055] FIG. 5 further depicts some example dimensions. In some embodiments, the distance from the lateral distal end of the first receiver tube 502a to the lateral distal end of the second receiver tube 502b can be about 1 inch to about 2.0 inches. In some embodiments, the distance from the lateral distal end of the first receiver tube 502a to the lateral distal end of the second receiver tube 502b can be about 1 .2 inches to about 1.8 inches. For example, the distance from the lateral distal end of the first receiver tube 502a to the lateral distal end of the second receiver tube 502b can be about 1.6 inches as depicted in the example of FIG. 5.

[0056] In some embodiments, the distance from the distal end of the main body 508 to the superior distal end of the ventilation connection tube 504 can be about 1.4 inches to about 3.0 inches. In some embodiments, the distance from the distal end of the main body 508 to the superior distal end of the ventilation connection tube 504 can be about 2.0 inches to about 2.8 inches. For example, the distance from the distal end of the main body 508 to the superior distal end of the ventilation connection tube 504 can be about 2.3 inches as depicted in the example of FIG. 5.

[0057] FIG. 6 depicts another cross-section view of the example multi-port adapter of FIG. 5 according to some embodiments of this disclosure. The features described in connection with FIG. 6 share the same features and functionality as FIGS. 1, 2, 3, 4, and 5. For example, the multi-port adapter 600 includes a main body 608 that shares the same features with multiport adapters 100, 200, 300, 400, and 500 including a main body 108, 208, 308, 408, and 508 respectively. Fig. 6 is a cross-section view of multi-port adapter 600 that includes a main body 608 defining a central cavity 624 and a main opening 622 to the central cavity 624 that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask. A first receiver tube 602a extends from the main body 608 and defines a first receiver port (e.g., 303a of FIG. 3) and a first lumen (e g., 320a of FIG. 3) extending between the first receiver port and the central cavity 624, the first receiver port and first lumen are sized to slidably receive an instrument (e.g., a bronchoscope). A ventilator tube 604 extends from the main body 608 and defines a third port 605 and a third lumen 626 extending between the third port 605 and the central cavity 624. An auxiliary tube 606 extends from the ventilator tube 604 and defines a fourth port 628 and a fourth lumen 630 extending between the fourth port 628 and the third lumen 626. The feature identified as 620 is a view of the internal opening of the first receiver tube 602a from the central cavity 624 and is where an instrument (e.g., a bronchoscope) would appear when inserted into the first receiver tube 602a. Fig. 6 is a cross section along the axis A-A identified in FIG. 5.

[0058] FIG. 6 depicts several example dimensions. In some embodiments, the angle between the central axis of the ventilator tube 604 and the distal end of the main body 608 is about 25° to about 38°. For example, the angle between the central axis of the ventilator tube 604 and the distal end of the main body 608 is about 33° as depicted by the example shown in FIG. 6.

[0059] In some embodiments, the inner diameter of the ventilator tube 604 is about 0.15 inches to about 0.5 inches. For example, the inner diameter of the ventilator tube 604 is about 0.4 inches as shown by the example of FIG. 6.

[0060] In some embodiments, the outer diameter of the ventilator tube 604 is about 0.4 inches to about 0.8 inches. For example, the outer diameter of the ventilator tube 604 is about 0.6 inches as shown by the example of FIG. 6.

[0061] In some embodiments, the inner diameter of the auxiliary tube 606 is about 0.05 inches to about 0.2 inches. For example, the inner diameter of the auxiliary tube 606 is about 0.16 inches as shown by the example of FIG. 6.

[0062] In some embodiments, the outer diameter of the auxiliary tube 606 is about 0.15 inches to about 0.45 inches. For example, the outer diameter of the auxiliary tube 606 is about 0.25 inches as shown by the example of FIG. 6.

[0063] In some embodiments, the inner diameter of the distal end of the main body 608 is about 0.4 inches to about 0.8 inches. For example, the inner diameter of the distal end of the main body 608 is about 0.6 inches as shown by the example of FIG. 6. In some embodiments, the outer diameter of the distal end of the main body 608 is about 0.5 inches to about 1.5 inches. For example, the outer diameter of the distal end of the main body 608 is about 1.0 inch as shown by the example of FIG. 6.

[0064] In some embodiments, the distance from the main opening 622 to the central cavity 624 of the main body 608 to the swivel mechanism 610 (e.g., 116 of FIG. 1) is about 0.3 inches to about 0.8 inches. For example, the distance from the main opening 622 to the central cavity 624 of the main body 608 is about 0.8 inches as shown by the example of FIG. 6.

[0065] In some embodiments, a connection of the swivel mechanism 610 is about 0.02 inches to about 0.06 inches. For example, a connection of the swivel mechanism 610 is about 0.04 inches as shown by the Example of FIG. 6.

[0066] In some embodiments, the inner distance from the distal end of the main body 608 to the interior proximal end of a ventilator tube 604 is about 0.8 inches to about 1.6 inches. For example, the inner distance from the distal end of the main body 608 to the interior proximal end of a ventilator tube 604 is about 1.3 inches as shown by the Example of FIG. 6.

[0067] Methods of using a multi-port adapter (e.g., any multi-port adapter described herein) include, for example, attaching equipment to the multi-port adapter in preparation for a procedure. A multi-port adapter described herein presents several advantages for medical procedures. It facilitates simultaneous actions, such as the introduction of multiple instruments, ventilation, and monitoring, without compromising the procedure's sterility or the patient's stability. The multi-port adapter's multiple ports provide separate, dedicated pathways, which reduces the risk of cross-contamination and enables efficient tool manipulation. This design enhances procedural efficiency by minimizing the need to exchange instruments and allows for continuous patient ventilation and monitoring, which is important for patient safety.

[0068] FIG. 7 depicts a flow diagram of an example method 750 for using a multi-port adapter (e.g., any multi-port adapter described herein). At 752, method 750 includes coupling a proximal end of an endotracheal tube or a laryngeal mask to a main body (e.g., main body 108 of FIG. 1) of the multi-port adapter comprising a first receiver tube (e.g., the first receiver tube 102a of FIG. 1), a second receiver tube (e.g., the second receiver tube 102b of FIG. 1), a ventilator connection tube (e.g., the ventilator connection tube 104 of FIG. 1), and an auxiliary tube (e.g., the auxiliary tube 106 of FIG. 1).

[0069] For example, a clinician can begin by attaching equipment to the multi-port adapter. For example, a proximal end of an endotracheal tube or laryngeal mask can be attached to the main opening (e.g., main opening 322 of FIG. 3) of the main body. To couple an endotracheal tube to the main opening of the multi-port adapter's main body, the proximal connector end of the endotracheal tube can be aligned with the multi-port adapter's main opening and then securely inserted, ensuring a tight seal to maintain ventilation integrity. Similarly, when using a laryngeal mask, the mask's tubing can be fitted over the main opening of the multi-port adapter and fastened in place, allowing for a continuous airway passage to the patient while enabling access for bronchoscopic instruments. This establishes a secure pathway for ventilation and access to the patient's airway.

[0070] At 754, method 750 includes coupling a ventilator circuit to the ventilator connection tube of the multi-port adapter. A ventilator circuit can couple to the ventilator connection tube via the third port (e.g., the third port 105 of FIG. 1) such that the patient is mechanically ventilated during a procedure.

[0071] At 756, method 750 includes coupling a CO2 monitoring device to the auxiliary tube. For example, a CO2 monitor is connected to the auxiliary tube via the fourth port (e.g., the fourth port 107 of FIG. 1), enabling continuous monitoring of the patient's CO2 levels throughout the procedure.

[0072] At 758, method 750 includes inserting a first bronchoscope into the first receiver tube of the multi-port adapter. For example, an instrument, such as a bronchoscope, is inserted into the first lumen (e.g., the first lumen 320a of FIG. 3) of the first receiver tube through the first receiver port (e.g., the first receiver port 103a of FIG. 1). In parallel, at 760, method 750 includes inserting a second bronchoscope into a second receiver port (e.g., second receiver port 103b of FIG. 1) of the multi-port adapter. For example, a second instrument — potentially another bronchoscope or a different instrument — is inserted into the second lumen (e.g., a second lumen 320b of FIG. 3) of the second receiver tube via the second receiver port (e.g., second receiver port 103b of FIG. 1). This multi-scope access allows for simultaneous procedures or views within the airway. OTHER EMBODIMENTS

[0073] It is to be understood that while the invention has been described in conjunction with the detailed description thereof, the foregoing description is intended to illustrate and not limit the scope of the invention, which is defined by the scope of the appended claims. Other aspects, advantages, and modifications are within the scope of the following claims.

Claims

WHAT IS CLAIMED IS:

1. A multi-port adapter, comprising: a main body defining a central cavity and a main opening to the central cavity that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask; a first receiver tube extending from the main body and defining a first receiver port and a first lumen extending between the first receiver port and the central cavity, the first receiver port and first lumen sized to slidably receive a first bronchoscope; a second receiver tube extending from the main body and defining a second receiver port and a second lumen extending between the second receiver port and the central cavity, the second receiver port and second lumen sized to slidably receive a second bronchoscope; a ventilator connection tube extending from the main body and defining a third port and a third lumen extending between the third port and the central cavity; and an auxiliary tube extending from the ventilator connection tube and defining a fourth port and a fourth lumen extending between the fourth port and the third lumen.

2. The multi-port adapter of claim 1, wherein central axes of the first receiver tube and the second receiver tube define an angle of between 30 and 40 degrees.

3. The multi-port adapter of any one of claims 1 to 2, wherein a diameter of the first receiver port and a diameter of the second receiver port is about 4 inches to about 10 inches.

4. The multi-port adapter of any one of claims 1-3, wherein a diameter of the first receiver tube and a diameter of the second receiver tube are about the same.

5. The multi-port adapter of any one of claims 1-3, wherein a diameter of the first receiver tube is different from a diameter of the second receiver tube.

6. The multi-port adapter of any one of claims 1-5, wherein the first receiver tube, the second receiver tube, the auxiliary tube, and the ventilator connection tube are fluidly connected to the central cavity of the main body.

7. The multi-port adapter of any one of claims 1-6, further comprising a swivel mechanism between a base at a distal end of the main body and an apex of the main body.

8. The multi-port adapter of any one of claims 1 -7, wherein the proximal end of the endotracheal tube is about 2 inches to about 12 inches.

9. The multi-port adapter of any one of claims 1-7, wherein the ventilator connection tube is sized to couple to a ventilator circuit.

10. The multi-port adapter of any one of claims 1-9, wherein the fourth port of the auxiliary tube is configured to couple with a proximal end of a CO2 monitoring device.

11. A multi-port adapter, comprising: a main body defining a central cavity, wherein the main body comprises: a base defining a main opening to the central cavity that is configured to couple with a proximal end of an endotracheal tube or a laryngeal mask; an apex that is configured for dynamic movement; and a swivel mechanism between the base and the apex of the main body, wherein the swivel mechanism is configured to enable dynamic movement of the apex relative to the base; and a first receiver tube extending from the apex of the main body and defining a first receiver port and a first lumen extending between the first receiver port and the central cavity, the first receiver port and first lumen sized to slidably receive a bronchoscope; a second receiver tube extending from the apex of the main body and defining a second receiver port and a second lumen extending between the second receiver port andthe central cavity, the second receiver port and second lumen sized to slidably receive a bronchoscope; a ventilator connection tube extending from the apex of the main body and defining a third port and a third lumen extending between the third port and the central cavity; and an auxiliary tube extending from the ventilator connection tube and defining a fourth port and a fourth lumen extending between the fourth port and the third lumen.

12. The multi-port adapter of claim 11, wherein a central axis of the first receiver tube and a central axis of the second receiver tube define an angle of between 30 and 40 degrees therebetween.

13. The multi-port adapter of any one of claims 11 to 12, wherein a diameter of the first receiver port and a diameter of the second receiver port is about 4 inches to about 10 inches.

14. The multi-port adapter of any one of claims 11-13, wherein a diameter of the first receiver tube and a diameter of the second receiver tube are about the same.

15. The multi-port adapter of any one of claims 11-13, wherein a diameter of the first receiver tube is different from a diameter of the second receiver tube.

16. The multi-port adapter of any one of claims 11-15, wherein the proximal end of the endotracheal tube is about 2 inches to about 12 inches.

17. The multi-port adapter of any one of claims 11-16, wherein the ventilator connection tube is sized to couple to a ventilator circuit.

18. The multi-port adapter of any one of claims 11-17, wherein the fourth port of the auxiliary tube is configured to couple with a proximal end of a CO2 monitoring device.

19. The multi-port adapter of claim 18, wherein the auxiliary tube is configured to continually monitor CO2.

20. A method for using a multi-port bronchoscopy adapter, comprising: coupling a proximal end of an endotracheal tube or a laryngeal mask to a main body of the multi-port adapter, wherein the multi-port adapter comprises: a first receiver tube; a second receiver tube; a ventilator connection tube; and an auxiliary tube; coupling a ventilator circuit to the ventilator connection tube; coupling a CO2 monitoring device to the auxiliary tube; inserting a first bronchoscope into the first receiver tube; and inserting a second bronchoscope into a second receiver port.

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