Dynamic Equivalent Body Load Estimator

By dynamically estimating the equivalent amount of exogenous drugs in vivo, the problem of difficulty in real-time monitoring of drug absorption and distribution status in the prior art is solved, and more accurate and effective drug management in diabetes management is achieved.

CN114173644BActive Publication Date: 2025-03-28DEXCOM INC
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Patent Information

Application Number
CN202080054094.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Priority Date
2019-06-19
Filing Date
2020-06-19
Publication Date
2025-03-28
Estimated Expiration
2040-06-19

AI Technical Summary

Technical Problem

It is difficult to accurately determine the absorption and distribution status of exogenous drugs in the body in real time, especially in diabetes management, and the concentration or quality of drugs is difficult to monitor in real time.

Method used

An adaptive body load estimation system is provided, which is used for decision support and artificial pancreatic algorithms in diabetes management software by dynamically estimating the equivalent amount of exogenous drugs in vivo and estimating based on prediction of glucose time series data.

Benefits of technology

Real-time dynamic estimation of exogenous drugs (such as insulin and carbohydrates) is achieved, which improves the accuracy and effectiveness of diabetes management and can dynamically adapt to individual metabolic changes.

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Abstract

Adaptive body load estimation of exogenous drugs responsive to transient (i.e., short-lived) physiological effects is provided. Dynamic estimation of the equivalent amount of body load exogenous drugs (XOB) such as insulin and / or carbohydrates remaining in the subject is performed based on predictions of glucose time series data. These estimates such as body load insulin (IOB) can be used in diabetes management software, for example, including decision support and / or artificial pancreas (AP) algorithms.
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