A kind of acylphosphine oxide compound and preparation method thereof
The "one-pot boil" method of metal efficient catalyzed metal phosphine oxide compounds are synthesized at room temperature, which solves the problems of high cost, high waste gas and difficult operation in the existing methods, and achieves efficient, environmentally friendly and low-cost industrial production.
Patent Information
- Application Number
- CN202211581095.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-12-09
- Publication Date
- 2025-03-28
- Estimated Expiration
- 2042-12-09
AI Technical Summary
The existing synthetic methods of acyl phosphine oxide compounds have problems such as high cost, high waste gas, and difficult to operate, and it is difficult to efficiently synthesize mono-acid and bis-acid phosphine oxide compounds under mild reaction conditions.
The "one-pot boil" preparation method of efficient metal catalysis is adopted. The acyl phosphine oxide compound is finally obtained by adding indium or a metal catalyst containing indium at room temperature, an ester solvent, a mixture of substituted phosphine chloride and an acid halide, and adding an oxidizing agent after the reaction is completed.
This method reduces equipment input and operation costs, reduces solvent loss, avoids solid waste and waste gas generation, has a simple process, is suitable for industrial production, and can efficiently prepare monoacyl and bisacylphosphine oxide compounds.