3414results about "Group 5/15 element organic compounds" patented technology

The application provides a process method for preparing (2-(3,6-dimethoxy-9H-carbazol-9-yl)ethyl) phosphonic acid, and particularly relates to the technical field of organic synthesis. The process method is that, under alkaline conditions, a halogenated phosphonate compound is added into a 3,6-dimethoxy-9H-carbazole solution to perform a reaction, hydrochloric acid aqueous solution is added after the reaction to perform acidolysis degreasing, and finally (2-(3,6-dimethoxy-9H-carbazol-9-yl)ethyl) phosphonic acid is obtained through extraction, reflux adsorption and beating purification. The process method uses 3,6-dimethoxy-9H-carbazole as a starting material, realizes the synthesis of the target product through one-pot reaction, has mild reaction conditions, uses non-toxic raw materials which are easy to obtain, has simple synthesis process, is convenient to operate, and has high separation yield.

The invention discloses a rare-earth metal arylamine group compound as well as preparation method and application thereof. The invention discloses the rare-earth metal arylamine group compound which is characterized in that a general formula of the rare-earth metal arylamine group compound is (2,6-R12PhNH)5LnLi2(THF)2, wherein Ln is a rear-earth metal selected from one of neodymium, samarium, ytterbium or yttrium; R1 is selected from one of hydrogen, methyl or isopropyl. The rare-earth metal arylamine group compound has the advantages that the rare-earth metal arylamine group compound has a definite structure; raw materials used in the preparation method are simple, easily obtained and cheap; the reaction process is simple and easily operated; the rare-earth metal arylamine group compound product is conveniently purified and the yield of the product is high; the rare-earth metal arylamine group compound has a high activity when acting as a single component catalyst to catalyze a hydrogen phosphine reaction of aldehyde or ketone and phosphite ester; the use amount of the catalyst is less; the yield is high; a substrate has wide universality; a new and simple method is provided for synthesis of a-hydroxyphosphonate.

The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.

The invention discloses a graphite piece silicon carbide coating and a preparation method thereof, and belongs to the technical field of inorganic non-metallic materials. The method comprises the following steps: firstly, carrying out surface polishing, cleaning and drying pretreatment on a graphite piece; then a solution containing phosphinazine functionalized silazane and a boron-silicon carlamide compound is adopted for spraying the pretreated graphite piece, drying and curing are conducted, and a surface modification layer is formed; and finally, placing the surface-modified graphite piece in chemical vapor deposition equipment, and depositing at specific temperature, pressure and atmosphere to form the silicon carbide coating. According to the method, uniform nucleation and crystallization of the silicon carbide coating are effectively promoted through unique surface modification treatment, and the compactness and uniformity of the coating and the binding force of the coating and a matrix are remarkably improved. The obtained coating graphite piece has excellent thermal corrosion resistance, oxidation resistance and mechanical property, the service life and the use frequency of the coating graphite piece in semiconductor epitaxial equipment are remarkably prolonged, the whole preparation process is environmentally friendly, and the coating graphite piece is suitable for coating treatment of a large graphite base material.

The invention discloses a dual-mechanism antibacterial photosensitizer as well as a preparation method and application thereof, and relates to the technical field of biomedical photoelectric functional materials. The invention relates to a triphenylamine derivative, which can realize fluorescence imaging of bacterial or fungal infection by utilizing fluorescence characteristics, can generate active oxygen under illumination to play a photodynamic therapy role, is suitable for preparing photodynamic therapy preparations and developing antibacterial materials, and can also be applied to the fields of environment and public health and tumor treatment. The problems that an existing photosensitizer is insufficient in broad spectrum, different in fungus drug resistance mechanism, limited in single treatment effect and the like can be effectively solved, and the photosensitizer has wide application prospects.

The invention provides a benzofuranone compound as well as a pharmaceutical composition and application thereof, and relates to the technical field of medicines. The benzofuranone compound is a compound as shown in a formula I, a stereoisomer thereof, a tautomer thereof, a crystalline hydrate thereof, a solvate thereof, a prodrug thereof or a pharmaceutically acceptable salt thereof. The benzofuranone compound and the pharmaceutical composition and the pharmaceutical preparation prepared from the benzofuranone compound can prevent or treat organ injury diseases, and have good treatment effects in kidney injury, liver injury, lung injury, brain injury and heart injury.

The invention provides a self-assembled monomolecular layer hole transport material based on a polycarbazole derivative and a preparation method and application thereof, and the self-assembled monomolecular layer hole transport material has a structure as shown in a formula I. The self-assembled monomolecular layer hole transport material is simple in structure, high in hole transport property, strong in interface passivation ability, high in thermal stability, and suitable for large-scale application; a polycarbazole derivative is taken as a mother nucleus, an alkyl / aryl chain is taken as a linking group, phosphoric acid is taken as an anchoring group, and rigid conjugated large-plane polycarbazole with a specific structure is taken as the mother nucleus, so that molecular accumulation can be improved, and the hole transport performance of the material can be improved. By taking a phosphate group as a tail end, single-molecule self-assembly can be realized, a perovskite interface can be passivated, the energy loss at the interface is reduced, and the battery performance is improved.

This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

The invention relates to a compound, a preparation method, a hole transport layer material, a photovoltaic device and a photovoltaic module. R1 and R4 are respectively and independently selected from amino and derivatives thereof, hydroxyl and derivatives thereof, methoxyl and derivatives thereof, sulfydryl and derivatives thereof, methylthio and derivatives thereof, thiophene groups and derivatives thereof, phosphate groups and derivatives thereof, carboxylic acid groups and derivatives thereof, and sulfonic acid groups and derivatives thereof; r2 and R3 are independently selected from alkyl, a phosphate group and derivatives thereof, a carboxylic acid group and derivatives thereof, a sulfonic acid group and derivatives thereof, and trimethoxysilyl propyl and derivatives thereof. The material is beneficial to improving the photoelectric conversion efficiency of photovoltaic devices and photovoltaic modules.

The invention discloses a phosphorus-sulfur synergistic flame retardant with high gas phase activity, a durable flame-retardant nylon fabric and a preparation method of the flame-retardant nylon fabric, and relates to the technical field of flame-retardant nylon fabric preparation.The preparation method of the phosphorus-sulfur synergistic flame retardant comprises the steps that 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide and polyepoxide are mixed and heated to be molten for a reaction, and the phosphorus-sulfur synergistic flame retardant is obtained; obtaining an intermediate after the reaction is finished; the intermediate and a thiophenethiol derivative are subjected to a click chemical reaction, and a 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide derivative containing phosphorus and sulfur is obtained; the preparation method comprises the following steps: dissolving a 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide derivative containing phosphorus and sulfur into a mixed solvent of ethanol and water, so as to obtain the phosphorus-sulfur synergistic flame retardant with high gas phase activity. The raw materials are safe and environmentally friendly, the preparation method is simple, and the prepared flame-retardant nylon fabric is excellent in flame retardance and washing resistance and free of pollution in the using process.

Provided in the present invention are compounds as VAV1 degradation agents and the use thereof. Specifically provided are compounds represented by formula (II), and tautomers, stereoisomers, pharmaceutically acceptable salts or prodrugs thereof. The compounds provided by the present invention have good efficacy, and can be used for preparing drugs for treating or preventing VAV1-related diseases.

The invention discloses a (methyl) acrylate monomer, a holographic recording medium, a preparation method and a related device.The structural formula of the (methyl) acrylate monomer is as shown in G1-G5. The preparation method is easy to operate and high in synthesis yield, and further, the holographic recording medium can be applied to holographic recording. The (methyl) acrylate monomer with the structure is introduced into the photopolymer type holographic recording medium, reverse migration of a short polymer chain can be effectively inhibited, and therefore the holographic recording medium with high sensitivity and high diffraction efficiency is obtained, and the invention further provides a preparation method of the holographic recording medium. The invention also provides a volume holographic grating, a holographic optical element and an optical device comprising the holographic recording medium.

The invention relates to the field of biomedicine, particularly provides a copper-based nano-enzyme as well as a preparation method and application thereof, and aims to solve the problems that in the prior art, clinical treatment on primary sclerosing cholangitis (PSC) is difficult in diagnosis and lacks of effective treatment drugs. The copper-based nano-enzyme comprises a nano-enzyme carrier and a copper-based nano-enzyme, wherein the nano-enzyme carrier is a two-dimensional nanosheet formed by copper ions, gallic acid and ursodesoxycholic acid through coordinate bonds; the probe molecule is a cyanine dye molecule connected to the surface of the nano-enzyme carrier through a covalent bond; wherein the fluorescence intensity of the copper-based nano enzyme is enhanced after the action of the alkaline phosphatase. The three functions of alkaline phosphatase responsive diagnosis, nano-enzyme catalytic treatment and ursodesoxycholic acid hepatic targeting are innovatively and synergistically integrated into one nano platform, the treatment function can be executed while specific imaging diagnosis is performed on diseases, and a new strategy is provided for diagnosis and treatment of diseases such as PSC.

The invention discloses an indolocarbazole compound, a perovskite solar cell and a preparation method, and belongs to the technical field of perovskite solar cells, the indolocarbazole compound provided by the invention is an organic small molecule material and has an asymmetric molecular structure, and an asymmetric conjugated structure system of the indolocarbazole compound enhances the molecular dipole moment and improves the photoelectric conversion efficiency. And the energy level matching is optimized. Meanwhile, benzene ring groups on side chains of molecules of the organic hole transport layer can further inhibit excessive aggregation of the molecules, uniform coverage is achieved, and efficient transport of carriers is achieved. Therefore, when the indolocarbazole compound organic small molecule material is used as a hole transport layer material for a perovskite solar cell, the energy levels of the highest occupied molecular orbital HOMO and the lowest unoccupied molecular orbital LUMO of the indolocarbazole compound organic small molecule material provided by the invention can be well matched with the energy level of an active layer material; therefore, the collection efficiency of current carriers is greatly improved, and the filling factor and the photoelectric conversion efficiency are improved.

The invention relates to a compound containing a thiophene group, a device and equipment. In the structural formula of the compound, R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are independently selected from hydrogen, halogen, cyano, trifluoromethyl, triphenylamine and derivatives thereof, methoxyl, aryl and derivatives thereof, cyanobiphenyl and naphthyl; the compound can be used for preparing a photovoltaic device and photovoltaic equipment and is used for improving the efficiency and stability of the photovoltaic device.

The invention discloses a dendritic (methyl) acrylate monomer, a holographic recording medium, a preparation method and a related device. Wherein the structural formula of the dendritic (methyl) acrylate monomer is shown as G1-G12, the preparation method of the dendritic (methyl) acrylate monomer is simple and easy to operate, and further, the dendritic (methyl) acrylate monomer with the structure is introduced into the photopolymer type holographic recording medium, so that the photopolymer type holographic recording medium is prepared. The invention further provides a preparation method of the holographic recording medium, a volume holographic grating containing the holographic recording medium, a holographic optical element containing the holographic recording medium and an optical device containing the holographic recording medium.

The invention discloses a polyamide acid-resistant nanofiltration membrane and arsenic removal application thereof in hair dye preparation. According to the amide acid-resistant nanofiltration membrane, a polyamine monomer and trimesoyl chloride are subjected to an interface reaction on an ultrafiltration supporting bottom membrane, and the polyamide acid-resistant nanofiltration membrane containing the Telogen structure is obtained. According to the method for removing the arsenic in the hydroxyethyl diphosphoric acid, a polyamide acid-resistant nanofiltration membrane containing a Troger structure is adopted for at least one time of filtration treatment, the concentration of arsenate in the hydroxyethyl diphosphoric acid after secondary filtration treatment is reduced to 4.60 mg / kg from 480.02 mg / kg, and the arsenic content of the hair dye prepared from the hydroxyethyl diphosphoric acid is smaller than 0.07 mg / kg. According to the polyamide acid-resistant nanofiltration membrane containing the Troger structure, which is obtained by adopting a limited preparation method, the acid resistance is greatly improved, the separation selectivity is higher, arsenic in hydroxyethyl diphosphate can be effectively removed, and the arsenic content in a hair dye is greatly reduced.

The invention provides a rare earth complex as well as a preparation method and application thereof. The chemical general formula of the rare earth complex is (Ln < 1x > Ln < 2y > Ln < 31-x-y >) (A) m (B) n, the rare earth complex provided by the invention has a self-assembly behavior, spherical nanoparticles can be formed through molecular aggregation, under ultraviolet irradiation, internal ligand molecules are better protected, the photobleaching process of the rare earth complex under natural conditions is slowed down, and the rare earth complex has better stability and higher weather resistance in the natural environment.

The invention discloses hydrolysis-resistant liquid phosphite ester and a preparation method and application thereof.The hydrolysis-resistant liquid phosphite ester is prepared by the steps that 2, 2, 4-trimethyl-1, 3-pentanediol and phosphorus trichloride or phosphite triester serve as raw materials, a cyclization reaction is conducted firstly, and then the hydrolysis-resistant liquid phosphite ester is obtained; and then carrying out nucleophilic substitution on Cl or aryl and alkyl on the cyclized intermediate by using higher saturated monohydric alcohol with more than C8, wherein the molecular structure is as shown in formula I in the specification. The liquid phosphite ester is novel liquid phosphite ester, the main body of the liquid phosphite ester is of a six-membered ring structure, the basic structure of the phosphite ester is reserved to the maximum extent, and the anti-oxidation effect of the phosphite ester is guaranteed; hydrophobic aliphatic chain structures on phosphorus atoms and branched chains of the phosphorus atoms prevent water molecules from approaching P-O bonds, so that the phosphorus atoms and the branched chains are prevented from being attacked by the water molecules, and the hydrolysis resistance is improved under the conditions that any additional amine hydrolysis-resistant agent is not used and any steric hindrance group is not introduced; good practical value, economic value and market prospect are realized.

The invention discloses a synthesis method of allyl phosphonic acid diester. According to the method, phosphorous acid diester and an allyl chloride compound are used as raw materials and react in the presence of a specific transition metal catalyst and alkali under the conditions of normal pressure and 45-60 DEG C to obtain the allyl phosphonic acid diester. The method has the advantages of mild reaction conditions, simple operation, high product yield (90-99%), no by-product, no generation of halogenated alkane gas and easy industrial production, and is suitable for the fields of polymer flame retardants, electronic materials, pesticide and medicine intermediates and the like.

The invention provides a host material, a dual-host-containing organic electroluminescent material and a preparation method and application thereof, the host material has a structure as shown in a general formula 1, the dual-host-containing organic electroluminescent material comprises a first host material and a second host material, and the mass ratio of the first host material to the second host material is 1: 99-99: 1, the first main body material is a compound with a structure as shown in a general formula 1, and the second main body material has a structure as shown in a general formula 2. Triplet excitons are dispersed on two main bodies by using the double main body material, so that triplet-triplet annihilation (TTA) is reduced, the driving voltage of the organic electroluminescent device is reduced, and the driving efficiency of the organic electroluminescent device is improved. And the luminous efficiency and the service life of the device can be improved.

The invention belongs to the field of organic electroluminescent materials, and discloses an organic electroluminescent material, an organic electroluminescent material containing double hosts and a luminescent device. The double-host-containing organic electroluminescent material comprises a first host material and a second host material, the first host material is the organic electroluminescent material and has a compound with a structure shown in a general formula 1, and the second host material is a compound with a structure shown in a general formula 2. The organic electroluminescent material or the organic electroluminescent material containing the double hosts is applied to the organic electroluminescent device, and has the advantages of low driving voltage, high luminous efficiency and long service life.

The present disclosure relates to compounds, compositions, and methods for treating diseases or disorders that are associated with aberrant tumor necrosis factor receptor 1 (TNFR1) signaling.

The invention discloses a triazine desulfurizer and a preparation method thereof, and belongs to the technical field of gas purification. The triazine desulfurizer is mainly prepared from the following raw materials in percentage by weight: 20 to 50 weight percent of triazine derivative, 10 to 15 weight percent of sterically hindered amine, 3 to 7 weight percent of stabilizer, 1 to 3 weight percent of synergist, 0.5 to 1.5 weight percent of penetrant, 0.5 to 1.5 weight percent of inhibitor, 1 to 2 weight percent of additive and the balance of water, the preparation method of the triazine derivative comprises the following steps: adding 2-(diphenylphosphino) ethylamine into a toluene solvent, adding a paraformaldehyde aqueous solution in batches under a stirring condition, and reacting for 2-8 hours to obtain the triazine derivative. According to the triazine desulfurizer and the preparation method thereof provided by the invention, the triazine derivative and the sterically hindered amine are taken as a host, and the stabilizer, the synergist, the penetrant, the inhibitor and the assistant are compounded, so that the scaling trend of the triazine desulfurizer in an oil and gas well can be slowed down, the dissolution rate of hydrogen sulfide and the mass transfer rate in a solution are increased, and the desulfurization reaction is promoted; the desulfurization effect and the desulfurization rate are improved, and meanwhile, a very good scale inhibition effect is also achieved.

The invention relates to a preparation method of a lithium difluoro bis (oxalate) phosphate concentrated solution, and belongs to the technical field of lithium battery electrolyte additives. Adding lithium oxalate into a solvent, stirring and dissolving to obtain a lithium oxalate solution; the method comprises the following steps: adding a modified fluorine ion chelating agent into a lithium oxalate solution, stirring, filtering, putting into a reactor, and slowly introducing phosphorus pentafluoride gas; after the introduction is finished, heating and stirring for reaction; after the reaction is finished, filtering reaction liquid to remove unreacted solid impurities, so as to obtain a lithium difluoro bis (oxalate) phosphate concentrated solution; the modified fluorine ion chelating agent is prepared from D301 ion exchange resin, dichloroethane, propylene-1-base boronic acid pinacol ester, mercaptoethyl guanidine dihydro bromide and sodium tert-butoxide. The lithium difluoro bis (oxalate) phosphate prepared by the method is high in purity and high in yield, and meets the use requirements of lithium ion battery electrolyte on lithium salt.

The invention discloses a hindered phenol monomer containing organic phosphorus heterocyclic rings as well as a preparation method and application of the hindered phenol monomer. The hindered phenol monomer has any one of the following structures: R is selected from-(CH2) b-or an aromatic ring, b is 3 or 4, and the aromatic ring comprises a benzene ring and / or a furan ring. The intrinsic flame-retardant anti-droplet polymer provided by the invention has the characteristics of excellent flame retardance and no droplet, and meanwhile, the intrinsic flame retardant is copolymerized into a molecular chain, so that the intrinsic flame-retardant anti-droplet polymer is not easy to migrate, does not permeate into the surrounding environment, is stable in property, can be used for injection molding and spinning, and can be used for preparing flame-retardant blocky products and fabrics; the composite material is used for interiors of electric appliances, switches, firefighter uniform, military uniform, automobiles, high-speed rails and other limited spaces.

The invention belongs to the technical field of energetic plasticizer preparation, and particularly discloses a method for preparing N-butyl nitroxyethyl nitramine through ionic liquid nitration. The method comprises the following steps: mixing an ionic liquid nitrating agent with butyl ethanolamine to obtain a mixed solution; and mixing the mixed solution with a catalyst and acetic anhydride, reacting, and carrying out post-treatment to obtain the N-butyl nitroxyethyl nitramine. According to the method, the ionic liquid with stable properties is adopted as the nitrating agent, the reaction is mild when the ionic liquid is mixed with the butylethanolamine, violent heat release caused when fuming nitric acid is in contact with the butylethanolamine is effectively avoided, and the ionic liquid precursor can be recycled through simple extraction after the reaction.

The invention discloses a lithium slag based salt corrosion resistant concrete pole and a preparation method thereof. The pole is made of lithium slag based geopolymer concrete. The concrete comprises the following components in parts by mass: 20-30 parts of dealkalized red mud, 15-25 parts of activated lithium slag, 10-15 parts of slag, 5-8 parts of silica fume, 6-10 parts of magnesium phosphate cement, 12-18 parts of a composite alkali activator, 25-35 parts of machine-made sand, 40-50 parts of gravel, 0.4-0.6 part of a polycarboxylic acid water reducer, 0.8-1.2 parts of composite fibers, 2-3 parts of a salt corrosion-resistant corrosion inhibitor and 25-35 parts of water. The outer surface of the electric pole is coated with an organic silicon-fluorosilicone resin hydrophobic coating; the salt-corrosion-resistant corrosion inhibitor is prepared by compounding nano silicon dioxide, a hydrotalcite precursor and a triphosphonic acid-based corrosion inhibitor, the concrete pole is obtained through the processes of red mud and lithium slag pretreatment, raw material mixing, centrifugal forming, curing and surface treatment, and has excellent salt corrosion resistance and mechanical property.

The invention discloses an organic long-chain zinc salt for a zinc secondary battery electrolyte and a preparation method and application thereof. The organic long-chain zinc salt comprises a long-chain group, an acidic group and zinc ions, the long-chain group comprises at least one of substituted or unsubstituted C8-16 alkyl groups, and the acidic group comprises at least one of a sulfonic acid group, a phosphoric acid group and a sulfuric acid group. The organic long-chain zinc salt serving as an electrolyte salt of the zinc secondary battery can be adsorbed on the surface of zinc to form a protective layer, so that the cycle life and the capacity retention ratio of the zinc secondary battery are effectively improved.