3 results about "Heredity" patented technology

The application provides a multi-source Parkinson's disease database integration method based on LEDD-UPDRS composite index alignment, and is applied to the technical field of data processing. In view of the heterogeneous problems of multi-source Parkinson's disease databases, the application integrates heterogeneous data of PPMI, PDBP and local queues, disassembles characteristics according to four modes of heredity and clinic, introduces a standardized term library and a BERT-BiLSTM-CRF model unified term adjusted in combination with medical corpus, generates a cross-library feature table; a storage architecture is constructed based on FlashROM mode to realize data storage and retrieval; a composite observation system is built with LEDD and UPDRS-III, consistency is verified by multiple methods, data is standardized, missing data is filled in combination with multiple models to generate an integrated data set; a double prediction model is built relying on the data set, and the advantages of the data are realized by a Cohen's d value verification method; finally, cross-library joint analysis is carried out, phenotype-genotype correlation modeling and causal inference are completed, and data support is provided for Parkinson's disease research and clinical prediction.

The application discloses a method for creating a DH line of eggplant by using anther culture and application thereof, and relates to the technical field of plant breeding. The application establishes a morphological index of a flower bud based on a calyx lobe separation state, replaces a time-consuming microscope examination procedure, and optimizes a combination of heat treatment and low-temperature pretreatment, so that the embryoid induction rate is significantly improved. Finally, through strict ploidy identification and self-pollination purification, a DH line with consistent traits and stable heredity can be obtained, an efficient pure line source is provided for eggplant hybrid breeding, and efficient conversion from a heterozygous genotype plant to a homozygous DH line is realized.

The application discloses a Brassica napus BnaREM1.3 gene and application of a coded protein thereof in regulation of drought resistance of crops. Overexpression strains of the BnaREM1.3 gene are obtained, and it is found that the drought resistance of the overexpression strains is significantly improved compared with wild type. Meanwhile, mutant strains of the BnaREM1.3 gene are obtained by using CRISPR / Cas9 technology, and it is found that the drought resistance of the mutant strains is significantly reduced compared with the wild type. The above results show that the Brassica napus BnaREM1.3 gene can be used to create Brassica napus with different drought resistance and stable heredity, and the BnaREM1.3 gene provides important gene resources and germplasm resources for drought resistance breeding of the Brassica napus, and has a wide application prospect in molecular design breeding of the Brassica napus.