806 results about "Mating" patented technology

Methods are provided for the synthesis and secretion of recombinant proteins preferably large mammalian proteins or hetero-multimeric proteins at high levels and for prolonged time in polyploid, preferably diploid yeast. These methods use various mating competent yeast, including Pichia. In a preferred embodiment, a first expression vector is transformed into a first haploid cell; and a second expression vector is transformed into a second haploid cell. The transformed haploid cells, each individually synthesizing a non-identical polypeptide, are identified and then genetically crossed or fused. The resulting diploid strains are utilized to produce and secrete fully assembled and biologically functional hetero-multimeric protein.

Porcine circovirus-2 (PCV-2) is a recently identified agent wherein the potential spectrum of PCV-2-associated disease has been expanded by evidence of vertical and sexual transmission and associated reproductive failure in swine populations. PCV-2 was isolated from a litter of aborted piglets from a farm experiencing late term abortions and stillbirths. Severe, diffuse myocarditis was present in one piglet associated with extensive immunohistochemical staining for PCV-2 antigen. Variable amounts of PCV-2 antigen were also present in liver, lung and kidney of multiple fetuses. Inoculation of female pigs with a composition including an immunogen from PCV-2 or an epitope of interest from such an immunogen or with a vector expressing such an immunogen or epitope of interest prior to breeding, such as within the first five weeks of life, or prior to the perinatal period, or repeatedly over a lifetime, or during pregnancy, such as between the 6th and 8th and/or the 10th and 13th weeks of gestation, can prevent myocarditis, abortion and intrauterine infection associated with porcine circovirus-2. In addition, innoculation of male and/or female pigs with the aforementioned compositions can be carried out to prevent transmission of PCV-2 from male to female (or vice versa) during mating. Thus, the invention involves methods and compositions for preventing myocarditis, abortion and intrauterine infection associated with porcine circovirus-2.

Mice are provided that comprise a reduction or deletion of ADAM6 activity from an endogenous ADAM6 locus, or that lack an endogenous locus encoding a mouse ADAM6 protein, wherein the mice comprise a sequence encoding an ADAM6 or ortholog or homolog or fragment thereof that is functional in a male mouse. In one embodiment, the sequence is an ectopic ADAM6 sequence or a sequence that confers upon a male mouse the ability to generate offspring by mating. Mice and cells with genetically modified immunoglobulin heavy chain loci that comprise an ectopic nucleotide sequence encoding a mouse ADAM6 or functional fragment or homolog or ortholog thereof are also provided.

According to the embodiment, the invention relates to the technical field of smart home, and discloses a feeding device of cooking equipment and the cooking equipment. The feeding device comprises a dividing device and a supplying device, wherein the dividing device adopts a worm or a disc provided with a charging groove; cooking raw materials in a storage box are supplied to a supplying device; and the dividing device and the supplying device are separated when the cooking raw materials are weighed. According to the supplying device, the cooking raw materials are conveyed into a pot body of the cooking equipment by virtue of a wind power device/vacuum device, or by virtue of a horizontal worm in a horizontal conduit and through self-gravity of the cooking raw materials, so that automatic feeding of the cooking equipment is achieved and workload of a user is reduced; a multipurpose mating device is provided for a plurality of intelligent home products, and a foundation is created for intelligent kitchen appliances or the smart home. The dividing device is applicable to such intelligent cooking equipment as an electric cooker, a bread maker, a frying machine, a soybean milk making machine, a bean curd machine, a stirrer, a coffee machine or a tea maker and the like.

Porcine circovirus-2 (PCV-2) is a recently identified agent wherein the potential spectrum of PCV-2-associated disease has been expanded by evidence of vertical and sexual transmission and associated reproductive failure in swine populations. PCV-2 was isolated from a litter of aborted piglets from a farm experiencing late term abortions and stillbirths. Severe, diffuse myocarditis was present in one piglet associated with extensive immunohistochemical staining for PCV-2 antigen. Variable amounts of PCV-2 antigen were also present in liver, lung and kidney of multiple fetuses. Inoculation of female pigs with a composition including an immunogen from PCV-2 or an epitope of interest from such an immunogen or with a vector expressing such an immunogen or epitope of interest prior to breeding, such as within the first five weeks of life, or prior to the perinatal period, or repeatedly over a lifetime, or during pregnancy, such as between the 6and 8and/or the 10and 13weeks of gestation, can lower viral titer, prevent myocarditis, abortion and intrauterine infection associated with porcine circovirus-2. In addition, innoculation of male and/or female pigs with the aforementioned compositions can be carried out to prevent transmission of PCV-2 from male to female (or vice versa) during mating. Thus, the invention involves methods and compositions for preventing myocarditis, abortion and intrauterine infection associated with porcine circovirus-2.

An adapter mechanism for facilitating re-orientation of a plug having an original orientation that is unsuitable for a peripheral device is presented. Re-orientation of a peripheral device is possible in an embodiment by advancing a symmetrical interface to another mating position exhibiting a hospitable orientation. An adaptor maintains USB functionality while providing the ability to reorient a fixedly attached peripheral. The adaptor mechanism also allows a USB wireless peripheral device with an antenna to plug directly into the USB receptacle connector on a digital device while orienting the antenna upwards to improve the quality of the transmitted and received signals.

The invention discloses an automatic depth-image registration method, which comprises the following steps: proceeding triangularization method for depth image; transmitting point cloud data into triangle grid data; finding the boundary point in the depth image according to the triangle grid data; calculating the character value of non-boundary vertex in the depth image; extracting character point set with projected surface character; finding the mating relationship as corresponding point among character points of two depth images; finding at least three couples of corresponding vertex; calculating the estimating value of movement of two depth images according to the corresponding point; adopting modified ICP algorism to optimize the result; finishing the precise registration of two depth images. The invention improves the speed and precision of registration, which reduces the calculating quantity with simple course.

A medical implant structure includes a pair of helically wound interlocking forms located on a cylindrical closure for an open headed medical implant and in a receiver between arms of the implant respectively. The interlocking forms each include overlapping gripping elements that engage mating elements during assembly to prevent radial splaying of the arms of the implant. The structure includes dove-tail-like and jig-saw-puzzle-like interlocking forms.

A connector (100) includes a metallic shell (5) having a mating frame part, said mating frame part including a number of sides together enclosing a hollow portion, and the hollow portion divided into two ports with different shapes; an insulative housing (1) having a base portion (11) and two juxtaposed tongue portions (12, 13) extending forwardly from the base portion, with a plurality of contacts (21, 22) mounted to the tongue portions, two lens members (4) received in lateral sides of one of the tongue portions; and the two tongue portions respectively received in the two ports.

A wing fold system of a wing of an aircraft. The system may include a first lock of a latch to prevent movement of a latch pin of the latch to prevent movement of an unfixed portion of the wing with respect to a fixed portion of the wing, the first lock may include a first cam configured to prevent the second lock from transitioning to a second engaged position until the first lock may be in a first engaged position via contact with a second cam of the second lock. A second lock of the latch, the second lock may include the second cam configured to prevent the first lock from transitioning away from the first engaged position until the second lock transitions away from the second engaged position.

The invention relates to the field of connectors for connecting a container with a fluid preparation device for preparing a fluid, in particular a container with a concentrate for the preparation of dialysis fluid. In order to simplify the handling during both the manufacturing process of such containers and the connection of such containers to the fluid preparation devices, the invention proposes a design of a connector (1) for connecting a first and second fluid line of the container with a third and fourth fluid line of the fluid preparation device with two lateraly spaced-apart mounting means (2, 4) which each incorporate one of two orifices (3, 5) terminating the first and second fluid lines. The invention also concerns a corresponding container and fluid preparation device.

The invention discloses a simple, convenient and efficient fixed-point gene editing method relating to the fields of transgenic animal preparation, gene functional study and biomedicines. A testis injection method is a sperm-mediated gene transferring method developed by utilizing the sperm capacity of actively combining, transferring and integrating an exogenous DNA. By using the method disclosed by the invention, an animal testis injection method is optimized, a carrier constructed by utilizing a clustered regularly interspaced short palindromic repeat system (CRISPR/Cas9) is integrated with a sperm chromosome through multi-point testis injection or seminiferous tubule microinjection, so that the aims of deleting, replacing and inserting genes are achieved. Then, a transgenic animal descendant is obtained through various approaches such as natural mating and artificial insemination. According to the method, the advantages of a CRISPR/Cas9 gene editing system are sufficiently utilized, and the existing transgenic animal system is combined, so that the complexity of in-vitro cell operation and requirement on expensive precise instruments/equipment are avoided while the gene modification animal obtaining efficiency is greatly increased.

A detector (60) is assembled with a lock arm (12) of a housing (10) to be movable between a standby position and a detection position. The detector (60) can move from the standby position to the detection position when the housing (10) is connected properly with a mating housing (90), and a movement thereof to the detection position is prevented when the housing (10) is connected partly with the mating housing (90). The detector (60) is formed with a window (69). A detecting main body (64) of the detector (60) is seen through the window (69) at the standby position, whereas an upper plate (24) of the lock arm (12) is seen therethrough at the detection position. The detector (60) is in a first color and the housing is in a second color different from the first color.

A package for companion products has two containers, each comprising a mating formation protruding in a direction toward the other container and defining a mating surface facing at an angle to the direction of protrusion and engaging the mating surface of the other container. Each container has a generally flat bottom and a center of gravity in vertical alignment with the generally flat bottom, whereby each container can stand independently of the other container. The shape of each container is the same as the other, and the containers are attached to one another. The shape enables the mating surfaces to be brought into engagement with one another by movement in a plane parallel to the bottoms of the containers.

The invention discloses a dark melolonthidae sex pheromone and a sex attractant. The sex pheromone comprises the following components: L-isoleucine methyl ester, (R)-(-)-linalool and 1-cyclohexane amino acid with the weight ratio of 2-9:1:0-1. The sex attractant comprises the dark melolonthidae sex pheromone and organic solvents; and the weight ratio of the sum of all components in the dark Melolonthidae sex pheromone and the organic solvents is 1:2.2-100. The dark melolonthidae sex pheromone is beneficial to protecting natural enemies, benefiting and eliminating pests, giving full play to integrated control power and improving the control effect when being used for forecasting insects and preventing dark melolonthidae pests by using a trapping method and an interference mating method; and in addition, the application of chemical pesticides is avoided so as to reduce the pollution, protect the environment and ensure remarkable economic benefits, social benefits and ecological benefits. The invention is suitable for the control of the dark Melolonthidae pests in farmlands.

A terminal (15) of a terminal-attached wire (10), in which the terminal (15) is connected to an end portion of a wire (11) and the end portion is sealed by a heat shrinkable tube (33), includes a terminal connecting portion (16) to be connected to a mating terminal, a wire connecting portion (18) to be connected to the end portion of the wire (11) and a coupling portion (22) coupling the terminal connecting portion (16) and the wire connecting portion (18) An opening end (33A) of the heat shrinkable tube (33) is mounted on the coupling portion (22), and a draining portion (32) for preventing adhering water from running down to the opening end (33A) is provided on a side closer to the terminal connecting portion (16) than the opening end (33A).