45 results about "Hydroxybenzoate" patented technology

To provide a timber antiseptic agent which exhibits superior safety and superior antibacterial performance with low influence on the human body and environment.SOLUTION: The present invention relates to a timber antiseptic agent containing an alkyl 4-hydroxybenzoate represented by formula (1) [where R represents an alkyl group having 5 to 10 carbon atoms] or a salt thereof.SELECTED DRAWING: None

Use of a lubricating composition in an ammonia combustion engine The present invention relates to the use of a lubricating composition comprising at least one alkali or alkaline-earth salt of hydroxybenzoic acid, optionally substituted by at least one hydrocarbon group, called hydroxybenzoate salt, in an ammonia combustion engine. It also relates to the use of said hydroxybenzoate salt as a corrosion retardant in an ammonia combustion engine. It also relates to a method for lubricating an ammonia combustion engine, comprising a step of bringing at least one mechanical part of said engine into contact with a lubricating composition comprising at least said hydroxybenzoate salt. Figure for abstract: None

A stabilized polymer composition comprising an organic polymeric material to be stabilized and a stabilizer composition comprising: at least one inorganic UV blocker, at least on hindered amine light stabilizer compounds, at least on hindered phenol antioxidant compound, at least one phosphite or phosphonite compound, and at least one thioester, wherein the stabilizer composition provides effective ultraviolet (UV) light stability, thermal stability and gas fade resistance to the stabilized polymer even when a hindered hydroxybenzoate, an organic UV absorber, an acid scavenger and / or a dialkylhydroxylamine are not present.

The present invention relates to the use of a lubricant composition comprising at least one alkali salt or alkaline earth salt of hydroxybenzoic acid, optionally substituted with at least one hydrocarbon group, referred to as hydroxybenzoate salt, in an ammonia combustion engine. The invention also relates to the use of said hydroxybenzoate salt as a corrosion retardant in an ammonia combustion engine. The invention further relates to a method for lubricating an ammonia combustion engine, comprising a step of bringing at least one mechanical part of said engine into contact with a lubricant composition comprising at least said hydroxybenzoate salt.

The application provides a white-borneol apricot kernel face mask liquid and a preparation method and application thereof, and relates to the technical field of cosmetics. The preparation raw materials of the white-borneol apricot kernel face mask liquid provided by the application include white petrolatum 5-20 parts, mono-diglyceride 1-10 parts, methyl p-hydroxybenzoate 0.01-8 parts, glycerol 1-10 parts, butanediol 0.05-10 parts, Tween-80 0.05-12 parts and compound extraction liquid 10-30 parts in terms of weight percentage. The white-borneol apricot kernel face mask liquid provided by the application has good moisturizing effect, is cold and heat resistant, has good stability and meets the microbial detection standard of cosmetics.

The invention relates to the technical field of p-hydroxybenzoic acid preparation, and discloses a p-hydroxybenzoic acid preparation method, which comprises: 1, mixing benzoic acid and a potassium hydroxide solution to form a potassium phenolate solution; 2, in an alkaline aqueous solution system, carrying out a directional hydroxylation reaction with a hydroxylation reagent in the presence of a phase transfer catalyst to generate potassium p-hydroxybenzoate; and step 3, converting the potassium p-hydroxybenzoate into p-hydroxybenzoic acid through acidification treatment. Compared with the prior art, the preparation method of p-hydroxybenzoic acid provided by the invention has the advantages of high efficiency, environmental protection and suitability for industrial production. The method comprises the following steps: reacting a potassium phenolate solution under an alkaline condition to generate potassium p-hydroxybenzoate under the catalysis of a phase transfer catalyst, and acidizing to obtain p-hydroxybenzoic acid. The method has the advantages of mild reaction conditions, high yield, few byproducts, easiness in industrial production and the like.

The invention discloses an anti-aging matting master batch for PE artificial grass and a preparation method of the anti-aging matting master batch, the anti-aging matting master batch is prepared from the following raw materials by weight: 45%-63% of PE resin, 0.6%-2.1% of a pigment agent, 4%-15% of a reinforcing agent, 2%-3.6% of a lubricant, 15%-30% of a filler, 0.35%-1.2% of an antioxidant, 0.5%-8% of an anti-aging agent, and 1%-3.7% of a matting agent, the reinforcing agent is prepared from the following raw materials by weight: 45%-60% of polyethylene glycol, 1%-3% of an anti-aging agent, and the matting agent is prepared from the following raw materials by weight: 1%-3% of a coupling The invention relates to the technical field of the invention, in particular to an anti-inflammatory and anti-inflammatory agent which comprises the following components in percentage by weight: 15.5%-33.6% of carboxymethyl cellulose, 8%-19.3% of hydroxybenzoate compounds and 2.5%-3.5% of potassium sorbate. Through mutual cooperation of the PE resin, the pigment agent, the reinforcing agent, the lubricant, the filler, the antioxidant, the anti-aging agent and the delustering agent, the physical properties of the master batch can be effectively improved, so that the master batch cannot generate an obvious color change phenomenon due to time or environmental factors in application, and the aesthetic degree of subsequent finished products is ensured.

To provide a dispersion liquid containing a paraben, which ensures excellent dispersion of the paraben in water and is capable of maintaining a dispersed state over an extended period of time.SOLUTION: The present invention relates to a dispersion liquid containing: a component (A), a benzyl 4-hydroxybenzoate represented by formula (1) or a salt thereof in an amount of 0.0001-70 mass%; a component (B), a surfactant having an aromatic group in an amount of 0.0001-10 mass%; and water, wherein the average particle diameter of the component (A) is 0.01-20 μm.SELECTED DRAWING: None

The invention discloses a high-temperature-resistant low-permeability polytetrafluoroethylene pipe which is prepared from a composite modified polytetrafluoroethylene composition, and the composite modified polytetrafluoroethylene composition comprises the following raw material components in parts by weight: 100 parts of polytetrafluoroethylene; 3.5-8 parts of a modified boron nitride grafted carbon nanotube composite filler; 12 to 23 parts of poly (p-hydroxybenzoate); and 1.7 to 4.5 parts of dipentaerythritol. The polytetrafluoroethylene base material is compounded and modified, so that the defects of poor heat-conducting property, insufficient high-temperature resistance and the like of polytetrafluoroethylene can be effectively overcome, and the prepared polytetrafluoroethylene pipe can better meet the application requirements of a heat exchanger pipe serving as a highly corrosive liquid; on one hand, the application effect of the polytetrafluoroethylene heat exchanger tube can be improved, and on the other hand, more possibilities can be provided for widening the application scene.

Cosmetic shake emulsion based on an O / W emulsion containing a) one or more alkane-1,2-diols b) Polyglyceryl-6 Stearates and Polyglyceryl-6 Behenates c) the preparation is free from polyacrylates (INCI: Carbomers), 2-ethylhexyl 2-hydroxybenzoate (INCI: Ethylhexyl Salicylate) and 3,3,5-trimethylcyclohexyl 2-hydroxybenzoate (INCI: Homosalate), 3-(4-methylbenzylidene)-camphor, 2-hydroxy-4-methoxybenzophenone (INCI: Oxybenzone), ethylhexyl 2-cyano-3,3-diphenylacrylate (INCI: Octocrylene), 2-ethylhexyl 3-(4-methoxyphenyl)prop-2-enoate (INCI: Ethylhexyl Methoxycinnamate) and EDTA and d) the preparation has a viscosity of less than 2000 mPas.

The invention belongs to the technical field of polymer functional aids, and discloses a layered composite metal hydroxide and a preparation method and application thereof, the chemical expression of the layered composite metal hydroxide is M < 2 + > 1-xM < 3 + > x (OH) 2 (A < n->) x / n.mH < 2 > O (at) P, m < 2 + > is selected from any one or two of Mg < 2 + >, Zn < 2 + >, Ni < 2 + >, Ca < 2 + >, Fe < 2 + > and Cu < 2 + >; m < 3 + > is selected from any one or two of Al < 3 + >, Co < 3 + >, Ti < 3 + >, Fe < 3 + > and Cr < 3 + >; a < n-> is selected from the group consisting of beta-(3, 5-di-tert-butyl-4-hydroxyphenyl) propionate, 3, 5-di-tert-butyl-4-hydroxybenzoic acid or beta-(3-tert-butyl-4-hydroxy-5-methylphenyl) propionate; x ranges from 0.1 to 0.5; n is 1 or 2; m ranges from 0.4 to 1.5; p is selected from chitosan, chitin, polyglucosamine, polyallylamine or polyethylene polyamine; based on the total weight of the layered composite metal hydroxide, the content of P is 5-15 wt%. The layered composite metal hydroxide provided by the invention has excellent migration resistance when being used as a polymer antioxidant.

The present invention relates to the use of a lubricant composition comprising at least one alkali salt or alkaline earth salt of hydroxybenzoic acid, optionally substituted with at least one hydrocarbon group, referred to as hydroxybenzoate salt, in an ammonia combustion engine. The invention also relates to the use of said hydroxybenzoate salt as a corrosion retardant in an ammonia combustion engine. The invention further relates to a method for lubricating an ammonia combustion engine, comprising a step of bringing at least one mechanical part of said engine into contact with a lubricant composition comprising at least said hydroxybenzoate salt.

The invention relates to a cleaning agent and a preparation method and application thereof, and belongs to the technical field of cleaning agents. The cleaning agent comprises the following components in percentage by mass: 84.7% of water, 0.2% of EDTA disodium, 4% of AES alcohol polyoxyethylene ether sodium sulfate, 1% of AS polystyrene foam, 1% of a nonionic surfactant, 1% of betaine, 2% of a degreaser, 0.4% of a penetrant, 0.2% of propylene glycol, 0.2% of a preservative, 2.4% of salt, 1% of sodium carboxymethyl cellulose, 0.5% of sodium benzoate and 1% of hydroxybenzoate. The cleaning agent has a good cleaning effect in the tunnel cleaning process, automobile oil stains can be directly washed away through a high-pressure water gun without scrubbing, and the labor cost is saved; in addition, the problem of environmental pollution is not found by monitoring the soil quality of surrounding water and the like; the cleaning agent is low in cost and has no corrosion effect on tunnel civil engineering structures, tunnel identification signs, cleaning equipment components and the like.

The invention discloses a cyproheptadine hydrochloride oral solution, which is prepared from cyproheptadine hydrochloride, hydroxypropyl-beta-cyclodextrin, a sweetening agent, sodium ethyl p-hydroxybenzoate, glycerol and a citric acid-sodium citrate buffer pair. The pharmaceutical composition has a crucial effect on the stability and other quality of an oral solution, after a stability test, the oral solution prepared from the pharmaceutical composition provided by the invention has the advantages of fewer impurities, stable quality and no turbid phenomenon, and the invention discloses a preparation method of the pharmaceutical composition.

The invention discloses a methyl 4-hydroxybenzoate organic single crystal as well as a preparation method and application thereof, and relates to the technical field of organic crystals. The method comprises the following steps: uniformly dispersing a methyl 4-hydroxybenzoate polycrystal material in acetone, and then filtering to remove impurities and insoluble substances to obtain a filtered solution; and standing the filtered solution at 0-5 DEG C for 12-48 hours to obtain the methyl 4-hydroxybenzoate organic single crystal. According to the invention, a low-temperature solvent evaporation method is combined with a low-temperature seed crystal method, so that the problems of poor crystal quality, small crystal size, complex process and high equipment requirement in the existing 4MHB crystal growth are effectively solved, and the large-size and high-quality 4MHB single crystal growth is realized.

The invention belongs to the technical field of oil field gathering and transportation, and discloses an efficient environment-friendly chemical paraffin remover and inhibitor which comprises the following components in percentage by weight: 15-50% of polyoxymethylene dimethyl ether, 20-40% of methyl p-hydroxybenzoate, 1-5% of a stabilizer and 1-2% of a surfactant. The preparation method comprises the following steps: S1, firstly preparing methyl p-hydroxybenzoate, and putting a finished product into a reaction kettle; s2, adding polyoxymethylene dimethyl ether into the reaction kettle, heating to 40-50 DEG C, and stirring for 0.5-1 hour; s3, adding a stabilizer, and stirring for 0.5-1 hour; s4, the surfactant is added and stirred for 0.5-1 h to obtain a finished product, the defects that an existing paraffin remover and inhibitor is large in toxicity, not ideal in effect and the like are overcome through a chemical method, the paraffin dissolving rate of the product is larger than 0.016 g.min <-1 >, and the product does not contain sulfur, chlorine, phosphorus and other harmful elements which are prone to poisoning a crude oil refining catalyst and corroding equipment.

The application belongs to the technical field of adhesives, and relates to a high-temperature-resistant hot melt adhesive film and a preparation method thereof.The high-temperature-resistant hot melt adhesive film comprises the following raw material components in parts by weight: polybutylene adipate glycol 60-80 parts, diphenyl methane diisocyanate 25-40 parts, chain extender 3-6 parts, 2,2-difluoroethyl-2-hydroxybenzoate 1-2 parts, and antioxidant 0.3-0.8 parts.The chain extender is obtained by the reaction of dehydroascorbic acid and 3,5-dimethoxyphenol, and can improve the stability of the hot melt adhesive film in a high-temperature environment.The 2,2-difluoroethyl-2-hydroxybenzoate is obtained by the reaction of salicylic acid and 2,2-difluoroethanol, and can enhance the bonding strength between the hot melt adhesive film and a textile fabric.The preparation method is simple in process, is suitable for industrialized production, and expands the application of the hot melt adhesive film to various textile fabrics such as shoe materials, clothes, and bags.

A stabilized polymer composition comprising an organic polymeric material to be stabilized and a stabilizer composition comprising: at least one inorganic UV blocker, at least on hindered amine light stabilizer compounds, at least on hindered phenol antioxidant compound, at least one phosphite or phosphonite compound, at least one thioester and at least one flame retardant, wherein the stabilizer composition provides effective ultraviolet (UV) light stability, thermal stability and gas fade resistance to the stabilized polymer even when a hindered hydroxybenzoate, an organic UV absorber, an acid scavenger and / or a dialkylhydroxylamine are not present.

The present invention discloses a method for quantitatively determining triphenylphosphonium compounds and their derived phosphine oxides in water, belonging to the technical field of analytical chemistry. The liquid chromatography-tandem triple quadrupole mass spectrometry technology is adopted, and its single standard is used as the qualitative substance, and methyltriphenylphosphonium iodide labeled with D3 is used as the recovery indicator. Using 13 ethyl p-hydroxybenzoate labeled with 13 C ( C-EtP) as the internal standard substance, the whole step of the quantitative method of the present invention is relatively simple, with high measurement sensitivity and accuracy. The content determination of 9 triphenylphosphonium compounds and their derived phosphine oxides can be completed within 8 minutes, providing reference data for accurately determining the content of triphenylphosphonium compounds and their derived phosphine oxides in water.

The invention provides a stabilizer formula for producing ammonia-free rubber and a preparation method, and belongs to the technical field of natural rubber production and processing. The stabilizer is prepared from, by weight, 3.6-4.8 parts of chitosan, 1-3 parts of sodium diacetate, 2-4 parts of methyl p-hydroxybenzoate, 1-2 parts of alginate, 3-4 parts of citric acid, 0.5-0.8 part of sodium sorbate and 1.2-1.6 parts of a specially-made active agent, camellia seed oil is adopted as a raw material to prepare the specially-made active agent, and the weight part ratio of chitosan to the specially-made active agent is 3: 1. The stabilizer disclosed by the invention can effectively prolong the preservation time of the rubber latex and improve the stability of the natural rubber latex through multiple mechanisms of inhibiting the growth of microorganisms, adjusting the pH value, enhancing a protective film and the like, and is beneficial to improving the environmental protection.

The invention discloses a modified organosilicon polymer material and a preparation method thereof, and relates to the field of polymer materials. When preparing the modified organosilicon polymer material, the present invention sequentially reacts silicon dioxide with 3-aminopropyltrimethoxysilane, 3-formyl-4-hydroxybenzoic acid methyl ester and sodium hydroxide to obtain modified silicon dioxide; 4-vinylphenylboronic acid is sequentially reacted with 3,4-dihydroxy-1-butene and 3-mercapto-1-propylamine to obtain a self-repairing monomer; self-repairing monomer, 1,3-bis (3-aminopropyl) tetramethyldisiloxane, 3-aminopropyltrimethylsilane, formaldehyde and glyoxal are reacted to obtain organosilicon polymer, and the organosilicon polymer is uniformly mixed with modified silicon dioxide to obtain a modified organosilicon polymer material. The modified organosilicon polymer material prepared by the present invention has antibacterial, wear-resistant, anti-aging, flame-retardant and self-repairing effects.

The utility model discloses a sodium methyl p-hydroxybenzoate drying machine which comprises a machine body, and a power assembly is arranged on one side of the machine body. A filter plate is arranged in the screening box, and the filter plate is inclined; the hole area on the filter plate can be adjusted; the side face, close to the lower end of the filter plate, of the screening box is provided with a discharging channel. The upper end of the crushing box is communicated with the discharging channel; the inner space of the crushing box is cylindrical, a blanking port communicated with the machine body is formed in the lower end of the crushing box, and a filter plate II is arranged in the blanking port; and a crushing structure is arranged in the crushing box. Before entering the drying machine, the raw materials are firstly screened, so that the raw materials entering the machine body are all crushed without caking, and the drying effect is improved.

The invention discloses a synthesis method of a benzofuro [3, 2-b] benzofuran compound, and belongs to the technical field of organic synthesis. According to the method, o-hydroxybenzoate compounds or halogenated derivatives thereof and methyl bromoacetate are taken as starting raw materials, and a target product is prepared through five steps of reaction: step 1, cyclization is performed at 0 DEG C to room temperature under an alkaline condition to obtain a benzofuran carboxylate intermediate; 2, sulfonylating by trifluoromethanesulfonic anhydride to obtain a sulfonate intermediate; 3, carrying out an etherification reaction with an o-halogenated phenol compound at the temperature of 80-120 DEG C; 4, hydrolyzing through inorganic strong base to obtain a benzofuran carboxylic acid intermediate; and 5, carrying out intramolecular ring closing at 80-180 DEG C under the action of a palladium catalyst and DBU. The raw materials are cheap and easy to obtain, the reaction selectivity is high, the total yield is stable, the substrate adaptability is wide, efficient synthesis of unilateral and bilateral halogen substituted derivatives of benzofuro [3, 2b] benzofuran compounds is successfully achieved, and the method has remarkable industrial application value.

The utility model discloses a crystallization device for producing methylparaben, which comprises a crystallization barrel, an outer cover plate is arranged on the crystallization barrel, a gear ring is movably connected inside the outer cover plate through a bearing, and an inner cover plate is movably connected inside the gear ring through a bearing. A stirring assembly is movably connected to the bottom of the inner cover plate, the bottom of the stirring assembly extends to the bottom end in the crystallization barrel, a plurality of stirring rods are fixedly connected to the outer side of the stirring assembly, a first gear and a second gear are driven to rotate through rotation of a main shaft, and finally a gear ring, a differential part and a stirring assembly body are driven to rotate; a stirring assembly and a circulating rod are utilized, the stirring rod stirs internal liquid and sucks liquid at the bottom to form circulation at the same time, heating is conducted in the circulation process, the liquid making contact with the inner wall of an electric heating pipeline is continuously changed in the circulation process, and therefore the situation that local overheating is not uniform in temperature can be avoided; and the heating process is relatively smooth and does not influence the crystallization quality.

The present invention relates to metabolic engineering of microbial hosts for the synthesis of products from oil palm empty fruit bunches (OPEFB). In one embodiment, the genetically engineered microorganism is Escherichia coli, which contains a metabolic pathway consisting of nine enzymes (11 genes) to utilize depolymerized lignin, namely vanillin, p-coumaric acid, p-hydroxybenzaldehyde, vanillic acid, p-hydroxybenzoic acid, and ferulic acid, to produce β-ketoadipate, which can then be converted into important derivatives such as adipic acid and levulinic acid. The enzymes are feruloyl-CoA synthetase (fcs), enoyl-CoA hydratase (ech), vanillin dehydrogenase (vdh), vanillate O-demethylase (vanAB; vanA and vanB), p-hydroxybenzoate hydroxylase (pobA), protocatechuate 3,4-dioxygenase {pcaGH; pcaG and pcaH), 3-carboxy-cis,cis-muconate cycloisomerase (pcaB), 4-carboxymuconolactone decarboxylase (pcaC), and β-ketoadipate enol-lactone hydrolase (pcaD).

The present application discloses a polyvinyl chloride material, which comprises, by mass: 55 to 65 parts of polyvinyl chloride, 10 to 25 parts of a plasticizer, 1 to 6 parts of a stabilizer, 0.5 to 1.5 parts of an anti-UV agent, 0.5 to 1.5 parts of a lubricant, 4 to 8 parts of a flame retardant, 5 to 15 parts of an ethylene-vinyl acetate copolymer elastomer, 1 to 3 parts of a processing aid, and 0.2 to 0.5 parts of a toner; the anti-UV agent comprises a combination of 2-(2H-benzotriazole-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol and 3,5-di-tert-butyl-4-hydroxybenzoate hexadecyl. The addition of ethylene-vinyl acetate copolymer as part of the plasticizer system reduces the risk of adhesive performance degradation caused by plasticizer precipitation and mixing with hot-melt adhesive, thereby extending the service life of the fixed position; the use of two anti-UV agents in combination can effectively improve the weather resistance of the material, reduce UV-induced yellowing, and thus extend the service life of the transparent optical fiber broadband.

The invention provides a preparation method of phenyl 4-hydroxybenzoate, which comprises the following steps: step S1, reacting 4-hydroxybenzoic acid with Boc anhydride under the action of Lewis acid to obtain 4-t-butyloxycarbonyloxybenzoic acid; s2, enabling the 4-tert-butyloxycarbonyloxy benzoic acid to react with phenol under the action of a condensation reagent, so as to obtain 4-tert-butyloxycarbonyloxy phenyl benzoate; and S3, carrying out a reaction on the 4-tert-butyloxycarbonyloxy phenyl benzoate under an alkaline condition to remove Boc so as to obtain the 4-hydroxybenzoic acid phenyl ester. According to the preparation method provided by the embodiment of the invention, the reaction condition is mild, the process is green and environment-friendly, the use risk of a chlorination reagent is avoided, and the reaction safety coefficient is improved.

The invention relates to the technical field of sewage treatment, in particular to a long-acting antibacterial deodorant for sewage and a preparation method of the long-acting antibacterial deodorant. The long-acting antibacterial deodorant for sewage is prepared from the following components in parts by weight: 0.2 to 0.3 part of 1, 2-benzisothiazolin-3-ketone, 0.3 to 0.5 part of p-tert-amylphenol, 0.1 to 0.2 part of methyl p-hydroxybenzoate, 4 to 6 parts of activated carbon, 4 to 6 parts of modified sustained release microspheres, 8 to 12 parts of modified polymer and 2 to 3 parts of modified lysozyme.

The invention relates to the technical field of traditional Chinese medicine external preparations, in particular to an O / W emulsion type ointment containing a corydalis amabilis extract and a preparation method of the O / W emulsion type ointment. The medicine is prepared from corydalis amabilis. Ethyl p-hydroxybenzoate is used as a preservative, glycerin is used as a humectant, lauryl sodium sulfate is used as an emulsifier, and the oil-phase matrix comprises stearyl alcohol, albolene and liquid paraffin. The ointment disclosed by the invention is brown yellow, fine and uniform in texture, good in fluidity and easy to coat; water solubility is good, and cleaning is easy. By utilizing the analgesic effect of decumbent corydalis tuber and the excellent drug release performance of the O / W emulsion type ointment matrix, the ointment can promote blood circulation to arrest pain, dispel wind and eliminate dampness, and improve arthralgia and lumbar muscle strain.

The invention relates to a novel tizanidine salt and a preparation method thereof, and belongs to the technical field of pharmaceutical chemicals. The novel tizanidine salt is obtained by selecting low-corrosivity and weak-acidity organic carboxylic acid as a ligand through a cooling crystallization or solvent evaporation crystallization mode. Wherein the organic carboxylic acid is selected from salicylic acid, p-hydroxybenzoic acid, maleic acid and pimelic acid. The formed tizanidine salicylate is in a P21 / n space group of a monoclinic system; the tizanidine p-hydroxybenzoate is an orthorhombic crystal system and has a Pbcn space group; the alpha crystal form of the tizanidine maleate is a P21 / c space group of a monoclinic system; the beta crystal form of the tizanidine maleate is a P21 / c space group of a monoclinic system; the tizanidine pimelate is an orthorhombic crystal system and has a Pna21 space group. The dissolution rate and the inherent dissolution rate of the tizanidine are improved in a mode of forming salt through crystal engineering, the obtained novel tizanidine salt has good stability, the bioavailability of the tizanidine is improved so that the tizanidine salt can give full play to the curative effect, the preparation condition is mild, the reproducibility is good, and large-scale production is easy to realize.