84 results about "Methylparaben" patented technology

The invention relates to the technical field of biology, and particularly discloses a recombinant collagen III and application thereof in preparation of gel. The recombinant collagen III is designed by optimizing functional area sequences of human I-type and III-type collagen, the amino acid sequence is shown as SEQ ID No.2, and the recombinant collagen III has the characteristics of high stability, good hydrophilicity and low immunogenicity. The preparation method comprises the steps of expression vector construction, escherichia coli induced expression, affinity chromatography purification and renaturation. The recombinant collagen III can be prepared into a gel dressing and comprises sodium alginate, methylparaben and other components. Experiments show that the gel can effectively promote cell proliferation and has no cytotoxicity; in a mouse skin injury model, the collagen can relieve inflammation, accelerate wound healing and inhibit scar formation, and the effect of the collagen is superior to that of natural human III-type collagen. The invention provides a safe and efficient novel material for wound repair, and is suitable for medical dressings and tissue engineering.

To provide a method for fixing carbon dioxide by which bubbles of carbon dioxide introduced into a solution can be made fine without increasing energy consumption.SOLUTION: A carbon dioxide fixation method comprising a precipitation step of introducing a gas containing carbon dioxide into a carbon dioxide fixation solution in which calcium ions are eluted to generate bubbles of the gas containing carbon dioxide in the carbon dioxide fixation solution, thereby reacting the calcium ions eluted in the carbon dioxide fixation solution with carbon dioxide to precipitate calcium carbonate, wherein the carbon dioxide fixation solution is an aqueous solution in which calcium ions are eluted in an aqueous solution of methylparaben.SELECTED DRAWING: Figure 1

The invention belongs to the field of personal care, and particularly relates to a glycoside derivative flexible liposome and a preparation method and application thereof, the glycoside derivative flexible liposome comprises a main shell material, a humectant, a wrapped raw material, an auxiliary shell material, a preservative and a solvent; the main shell material is phosphatidylcholine, and the auxiliary shell material is polyquaternium-51; the preservative is any one or more of 1, 2-hexanediol, p-hydroxyacetophenone, methylparaben, phenoxyethanol and caprylyl glycol; the moisturizing agent is butanediol; the wrapped raw material is hydroxypropyl tetrahydrofurantriol; the solvent is deionized water. According to the invention, the permeability and penetration depth of the glassine and the concentration of the glassine at a target position are improved by utilizing a flexible liposome wrapping technology, the bioavailability of the glassine is improved, and the addition amount is reduced under the condition of realizing the same tightening and anti-wrinkle effects, so that the cost is reduced.

The invention relates to the technical field of wash supplies, and particularly discloses anti-hair loss essence and a preparation method thereof. The anti-hair-loss essence is prepared from the following raw materials in percentage by mass: 60-75% of water, 10-20% of ethanol, 1-3% of a cacumen biotae extract, 1-3% of an angelica root extract, 1-3% of a polygonum multiflorum root extract, 0.5-2% of a ganoderma atrum extract, 0.5-2% of a trollius chinensis bunge extract, 0.5-2% of a cultivated nigella glandulifera seed extract, 0.3-1% of a flat walnut seed extract, 0.1-0.5% of a radix sophorae flavescentis extract, 0.1-0.5% of chlorphenesin and 0.05-0.3% of methylparaben. The traditional Chinese medicine composition is prepared from the following components in percentage by weight: 0.01-0.20% of a ginseng extract, 0.01-0.20% of a selaginella tamariscina extract and 0.01-0.20 The anti-hair loss essence disclosed by the invention has the beneficial effects that the anti-hair loss essence adopts various natural plant extracts as main raw materials, the various natural plant extracts have a synergistic effect, the hair loss problem is comprehensively solved from multiple aspects of improving scalp blood circulation, nourishing hair follicles, regulating endocrine, resisting bacteria and diminishing inflammation and the like, and the anti-hair loss effect is remarkable.

The invention provides a detection method for related substances in loxoprofen sodium oral solution. The adopted ternary mobile phase system solves the interference of auxiliary materials in the low absorption band on the detection of known impurities, thereby avoiding the problem of missed detection and insufficient detection of impurities, effectively solving the interference of auxiliary material methylparaben on the detection of impurities when the related substances are determined, and the types and numbers of impurities to be monitored are large, the separation between various impurities, between impurities and main components, and between impurities and auxiliary materials is good, the related substances in the loxoprofen sodium oral solution can be quickly and accurately monitored, and the method has important significance for the quality evaluation of the loxoprofen sodium oral solution.

The invention relates to cream for repairing radiodermatitis and a preparation method of the cream, and belongs to the technical field of biomedical skin treatment. The cream consists of the following components in percentage by weight: 8% of glycerin monostearate, 6% of stearic acid, 5% of white vaseline, 4% of liquid wax, 1-2% of tea tree oil, 1-2% of eugenol, 1-2% of vitamin E, 3% of trehalose, 8% of polyethylene glycol (PEG-400), 10% of glycerol, 0.5% of methylparaben, 1% of triethanolamine and the balance of purified water. According to the cream disclosed by the invention, the natural traditional Chinese medicine component eugenol and the natural substance vitamin E are utilized to synergistically enhance the anti-oxidation and bacteriostatic effects, and the tea tree oil, the trehalose and other effective components are utilized to repair radiodermatitis from multiple aspects of anti-inflammation, bacteriostasis, antioxidation, promotion of skin barrier repair and the like. The cream is simple in component, good in treatment effect, high in safety and convenient to produce and process, and can be popularized and applied to treatment of radiodermatitis.

The invention discloses a hydrogel patch for promoting blood circulation to remove meridian obstruction and a preparation method thereof. The formula of the hydrogel patch for promoting blood circulation to remove meridian obstruction comprises a traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction, an oil-in-water emulsion for promoting blood circulation to remove meridian obstruction, sodium polyacrylate, polyacrylic acid, glycerol, azone, dihydroxyaluminum aminoacetate, tartaric acid, disodium ethylene diamine tetraacetate, methylparaben and deionized water. The traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction is 70% ethanol extract of vinegar-processed rhizoma corydalis, ligusticum wallichii, philippine flemingia root, safflower, frankincense, myrrh, radix angelicae and liquorice; the oil-in-water emulsion capable of promoting blood circulation to remove meridian obstruction is prepared from a vinegar rhizoma corydalis sesame oil extract, wintergreen oil, methyl glucose sesquistearate, stearate, cetostearyl alcohol, polydimethylsiloxane and deionized water; the blood-activating collateral-dredging hydrogel patch has no skin irritation, belongs to weak sensitization, and has the function of assisting in relieving pain.

The invention provides a teak camel moth artificial feeding feed and a teak camel moth artificial feeding method, the feed comprises the following components by weight: 8% of wheat germ powder, 4% of soybean meal, 4% of yeast powder, 2% of casein, 2% of sucrose, 1.8% of agar powder, 1.5% of cellulose, 0.8% of Webster salt, 0.6% of vitamin C, 0.2% of sorbic acid, 0.3% of methyl p-hydroxybenzoate, 0.1% of cholesterol, 0.1% of choline chloride, 0.05% of inositol, 0.01% of folic acid, and the balance of water. And the balance of deionized water. The invention further provides an artificial feeding method of teak camelmoths, and the artificial feeding method comprises the steps of 1, adult mating and egg laying, 2, egg disinfection and incubation and 3, larva rearing. The feed does not contain host material teak leaves, and full-artificial continuous large-scale feeding of the teak camelmoths can be achieved.

An oral liquid suspension comprising atomoxetine or a pharmaceutically acceptable salt thereof is disclosed, formulated at a concentration of about 20 mg / mL for the treatment of attention-deficit / hyperactivity disorder (ADHD). The suspension includes a dual preservative system (methylparaben and sodium benzoate), sweeteners, pH buffers, suspending agents, co-solvents, flavorants, and colorants. The composition demonstrates bioequivalence to Strattera® capsules, robust antimicrobial efficacy meeting USP <51> criteria, and physicochemical stability over 24 months in validated high-density polyethylene containers with child-resistant closures. The 20 mg / mL concentration enables precise dose titration for pediatric and dysphagic patients. Palatability is optimized through validated flavor masking studies, supporting high patient adherence. The invention further provides scalable manufacturing methods, quality control specifications, and methods of use for treating ADHD, offering a stable, safe, and patient-friendly alternative to solid oral dosage forms.

The invention discloses a medical recombinant collagen repair liquid preparation method, which is prepared from the following raw materials by weight: 1-100 g of recombinant collagen, 1-100 g of sodium hyaluronate, 1-100 g of glycerol, 1-100 g of purified water, and 1-10 g of methylparaben. The medical recombinant collagen repair liquid can effectively repair skin barriers and treat skin injuries caused by multiple reasons such as burns, wounds and laser postoperations, and meanwhile, the medical recombinant collagen repair liquid has remarkable advantages in the fields of gynecological inflammation treatment, private anti-aging, micro-ecological balance maintenance, wound healing promotion, tissue elasticity and compactness improvement and the like. Adverse reactions such as allergy are effectively reduced, and the requirements of people for high efficiency and safety of skin repairing products are met.

The present invention relates to the field of sewage treatment technology, and more particularly to a long-lasting antibacterial deodorant for sewage and a preparation method thereof. The long-lasting antibacterial deodorant for sewage is prepared from raw materials comprising the following components in parts by weight: 0.2-0.3 parts of 1,2-benzisothiazolin-3-one, 0.3-0.5 parts of p-tert-amylphenol, 0.1-0.2 parts of methyl parahydroxybenzoate, 4-6 parts of activated carbon, 4-6 parts of modified sustained-release microspheres, 8-12 parts of a modified polymer, and 2-3 parts of modified lysozyme.

The present application discloses a method for preparing a brivaracetam solution and the brivaracetam solution thereof, belonging to the field of medical technology. The method for preparing the brivaracetam solution comprises the following steps: (1) preparing solution 1: mixing a mixture including sodium carboxymethylcellulose and glycerol with purified water and stirring to obtain solution 1; (2) preparing solution 2: mixing purified water, methylparaben, sodium malate, malic acid, sucralose, crystalline sorbitol solution, brivaracetam, and glycerol and stirring to obtain an intermediate solution, mixing the intermediate solution with essence and stirring to obtain solution 2; (3) mixing solution 1, solution 2 and purified water, stirring, and filtering to obtain a brivaracetam solution. The method improves the clarity of the solution by controlling the order and temperature of addition of each auxiliary material, and the obtained brivaracetam solution has good stability and is free of precipitation and degradation impurities.

The disclosure relates to methods for amplifying a target nucleic acid. The methods include performing an amplifying step comprising contacting the nucleic acid with a polymerase, dNTPs, one or more set of primers specific for the nucleic acid, and an amplification enhancer that is methyl paraben or a derivative thereof. Also described are kits and reaction mixtures for the amplification of a target nucleic acid in the presence of the amplification enhancer, as well as methods for enhancing nucleic acid amplification.

The invention discloses preparation and application of a degradable polyester and anti-radiation material based on methylparaben, and belongs to the field of preparation of degradable polymers and anti-radiation materials, and the degradable polyester based on methylparaben is used for preparing environment-friendly shopping bags, environment-friendly food packaging bags, take-out packaging boxes and packaging bottles / barrels of food, drinking water and beverages. The composite material can be processed into an organic-inorganic composite material, has good toughness and excellent radiation resistance, and is used for manufacturing base materials of radiation-proof clothes, radiation-proof jackets, radiation-proof vests, radiation-proof jackets and radiation-proof raincoats.

The invention provides a compound lithospermum erythrorhizon lip balm for improving chronic cheilitis, which is characterized by being prepared by adding methylparaben into the following raw materials: 6g of lithospermum erythrorhizon, 1g of angelica sinensis, 1g of divaricate saposhnikovia root, 1g of radix rehmanniae recen, 1g of liquorice, 1g of radix angelicae, 1g of frankincense, 1g of myrrh, 0.01 g of methylparaben, 0.1 g of vitamin E, 30g of beewax and 150mL of olive oil. The preparation method comprises the following steps: mixing Chinese angelica, divaricate saposhnikovia root, raw rehmannia root, licorice, dahurian angelica root, frankincense and myrrh, frying with olive oil to obtain medicinal oil A, adding lithospermum, heating, filtering, cooling the obtained medicinal oil B to 60 DEG C, adding vitamin E to obtain medicinal oil C, adding heated and melted beeswax, uniformly mixing, adding methylparaben, and pouring. The invention further provides application, and the prepared compound lithospermum erythrorhizon lip balm is used for improving chronic cheilitis. The compound lithospermum erythrorhizon lip balm for improving chronic cheilitis prepared by the invention can be used for improving chronic cheilitis, is safe and effective, and can relieve lip symptoms of chronic cheilitis.

The invention relates to the technical field of intelligent production of cosmetics, and discloses an intelligent optimization-based body lotion preparation method and a product, the preparation method comprises the following steps: adding a first raw material group, PEG-100 stearate and the like into an oil phase pot, stirring and heating to 80 DEG C; adding water into an emulsifying pot, then sequentially adding the second raw material group, methylparaben and EDTA disodium, stirring and heating, then pouring an oil phase material into the emulsifying pot, collecting current particle size information of particles to determine an initial homogenizing parameter, comparing with historical particle size information to calculate similarity, and judging whether to adjust the parameter or not according to the maximum similarity to obtain a final homogenizing parameter. After homogenizing, keeping the temperature and stirring, adding dipotassium glycyrrhizinate, vacuumizing and keeping the temperature for 20 minutes; cooling to 45 DEG C, adding phenoxyethanol, stirring for 10 minutes, cooling to 35 DEG C or below, filtering, and taking a solid phase to obtain the body lotion. Through precise parameter control and a dynamic adjustment mechanism, the production process of the body lotion is optimized, and the raw material mixing uniformity and the particle stability are improved.

The invention relates to the technical field of skin care products, in particular to a preparation method of sunscreen cream. The preparation method of the sunscreen cream comprises the following steps: step 1, respectively selecting a proper amount of rhodiola rosea, polygonum cuspidatum, roses and green tea, crushing, and then respectively adding 70% ethanol with a solid-liquid ratio of 8-15 times to the rhodiola rosea, the polygonum cuspidatum, the roses and the green tea; step 2, taking a rhodiola rosea extracting solution, a polygonum cuspidatum extracting solution, a rose extracting solution and a green tea extracting solution as plant compound solutions; 3, preparing a proper amount of 1% sodium ethylene diamine tetracetate solution as a water phase; 4, selecting a proper amount of titanium dioxide, stearic acid, C16-C18 alcohol, vaseline, olive oil, methylparaben and the plant compound liquid as raw materials, heating in a water bath, stirring to form an oil phase, and then adding the mixed emulsifier; step five, adding the oil phase into the water phase while stirring, and then carrying out homogeneous emulsification by using a homogenizer; and 6, carrying out thermal insulation emulsification for 20 min, cooling to 50 DEG C, adding essence, fully stirring, cooling to room temperature (25 DEG C), stopping stirring, and carrying out discharging and filling.

The invention discloses a whitening facial cleanser and a preparation method thereof, and relates to the field of skin care products. The whitening facial cleanser is prepared from 35 to 42 weight percent of a cleaning agent, 1 to 2 weight percent of a whitening and freckle-removing agent, 0.8 to 1.2 weight percent of a skin conditioner, 4 to 8 weight percent of an emollient, 4 to 6 weight percent of a humectant, 0.3 to 0.5 weight percent of a preservative, 0.05 to 0.1 weight percent of a chelating agent, 4 to 4.5 weight percent of a thickening agent, 0.2 to 0.5 weight percent of an aromatic, 0.8 to 1.0 weight percent of a pH regulator and the balance of a solvent. The cleaning agent is prepared from sodium lauroyl isethionate, sodium cocoyl aminopropionate, cocamidopropyl betaine and sodium lauroyl sarcosinate according to the weight ratio of (3.5 to 4.5) to 1 to 1 to 1; the preservative comprises DMDM hydantoin and methylparaben in a weight ratio of (3-4): 1. The whitening facial cleanser provided by the invention has both cleaning power and mildness, and also has a whitening effect.

The present invention belongs to the field of personal care, and particularly relates to a glycoside derivative flexible liposome, a preparation method and an application thereof. The glycoside derivative flexible liposome comprises a main shell material, a humectant, a raw material to be encapsulated, an auxiliary shell material, a preservative and a solvent. The main shell material is phosphatidylcholine, and the auxiliary shell material is polyquaternium-51. The preservative is any one or more of 1,2-hexanediol, p-hydroxyacetophenone, methylparaben, phenoxyethanol, and caprylyl glycol. The humectant is butanediol. The raw material to be encapsulated is hydroxypropyltetrahydrofurantriol. The solvent is deionized water. The present invention uses a flexible liposome encapsulation technology to improve the permeability and penetration depth of boswellia serrata extract and its concentration at the target site, improve the bioavailability of boswellia serrata extract, reduce the addition amount under the condition of achieving the same firming and anti-wrinkle effect, and thus reduce the cost.

An oral liquid suspension comprising atomoxetine or a pharmaceutically acceptable salt thereof is disclosed, formulated at a concentration of about 20 mg / mL for the treatment of attention-deficit / hyperactivity disorder (ADHD). The suspension includes a dual preservative system (methylparaben and sodium benzoate), sweeteners, pH buffers, suspending agents, co-solvents, flavorants, and colorants. The composition demonstrates bioequivalence to Strattera® capsules, robust antimicrobial efficacy meeting USP <51> criteria, and physicochemical stability over 24 months in validated high-density polyethylene containers with child-resistant closures. The 20 mg / mL concentration enables precise dose titration for pediatric and dysphagic patients. Palatability is optimized through validated flavor masking studies, supporting high patient adherence. The invention further provides scalable manufacturing methods, quality control specifications, and methods of use for treating ADHD, offering a stable, safe, and patient-friendly alternative to solid oral dosage forms.

The invention discloses an anti-oxidation skin care product formula capable of diminishing inflammation, relieving itching, moistening skin and delaying senescence, and relates to the technical field of anti-oxidation skin care products. The anti-oxidation skin care product formula comprises the following raw materials: a purslane extract, alum, purified water, glycerol, coconut oil, stearic acid, triethanolamine, methylparaben, plant essential oil, vitamins, beewax, sodium carboxymethyl cellulose and titanium dioxide, the purslane extract has good anti-inflammatory, anti-oxidation and antibacterial effects, is helpful for relieving skin inflammation, reducing redness, swelling and irritation, and has a good anti-inflammatory, anti-oxidation and antibacterial effect. The anti-oxidation skin care product has obvious effects of resisting oxidation, delaying senescence and moistening skin and beautifying, alum has astringing and antibacterial characteristics, is beneficial to reducing skin grease secretion and astringing pores, also has a certain antibacterial effect and can kill parasites to relieve itching, and after being used, the anti-oxidation skin care product can relieve skin inflammation, reduce redness and swelling and irritation, moisten skin, preserve moisture and resist oxidation, and can be used as an anti-oxidation skin care product. The skin aging is delayed.

The invention belongs to the technical field of medicine, and particularly relates to poloxamer hydrogel for treating haemorrhoids, the main component of the hydrogel is poloxamer, the content of the poloxamer is 2.5-3.5%, and the hydrogel can further contain carbomer, edetate disodium, glycerol, triethanolamine and methylparaben, and the haemorrhoids hydrogel is remarkable in curative effect, small in irritation and free of toxic and side effects. The traditional Chinese medicine composition can be used for treating symptoms such as anal falling swelling pain, mucosa hyperemia and hematochezia caused by internal hemorrhoids, external hemorrhoids and mixed hemorrhoids.

The invention provides an HPLC (High Performance Liquid Chromatography) detection method of adapalene gel and application thereof, and particularly relates to the technical field of analysis and detection of medicinal components. The HPLC detection method of the adapalene gel is used for simultaneously detecting the contents of adapalene, methylparaben and phenoxyethanol in the adapalene gel; according to the HPLC detection method, a mixed solution of a mobile phase A and a mobile phase B is used as a mobile phase, and a sample solution to be detected is subjected to gradient elution; the initial volume ratio of the mobile phase A to the mobile phase B is (78-82): (22-18); in the gradient elution, the volume ratio of the mobile phase A to the mobile phase B is from (78-82): (22-18) to (28-32): (72-68) and finally returns to (78-82): (22-18). The detection method is simple and can be used for simultaneously determining the contents of adapalene, methylparaben and phenoxyethanol.

The invention discloses essence containing mint and chrysanthellum indicum rose essential oil, the essence comprises a liquid part and an oil body part, the liquid part comprises water, propylene glycol, butanediol, glycerol, tremella fuciformis seed extract, triethanolamine, methylparaben, carbomer, xanthan gum and trace components; the oil body part is prepared from cyclomethicone, polydimethylsiloxane, vanillyl butyl ether and rose oil. The trace components comprise capryloyl hydroximic acid, glycerol caprylate, sodium polyacrylate, a chrysanthellum indicum extract, a mint extract, a portulaca oleracea flower / leaf / stem extract, a pelargonium graveolens extract, sodium hyaluronate, lactose, hydroxypropyl methyl cellulose, tocopheryl acetate, ascorbyl palmitate, CI 77007, an aloe barbadensis leaf extract and a radix sophorae flavescentis extract.

Provided herein are 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl) pyrazolo [3, 4-d] pyrimidin-1-yl] piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl) piperazin-1-yl] pent-2-enenitrile (identified herein as Compound (I), as well as, for example, 2-(4-fluoro-4-(2-fluoro-4-phenoxy-phenyl) pyrazolo [3, 4-d] pyrimidin-1-yl) piperidine-1-carbonyl)-4-methyl-4-[4-(oxetan-3-yl) The present invention relates to a substantially crystalline solid form of a pharmaceutically acceptable salt selected from the group consisting of HCl, oxalate and / or maleate, or alternatively as a pharmaceutically acceptable co-crystal of methyl parahydroxybenzoate, and pharmaceutical compositions comprising said substantially crystalline form. # imgabs0 #

This invention relates to the fields of fine chemicals and polymer materials technology, specifically a method for manufacturing toy adhesives. It includes steps for preparing the adhesive base material, preparing borax solution, and cross-linking molding. Polyvinyl alcohol, guar gum, methylparaben, etc., are prepared as base materials, which are then reacted with borax solution to undergo a cross-linking reaction. The core of this invention is the strict limitation of specific high-temperature ranges and constant-temperature stirring times during the base material preparation process, which promotes the complete extension and entanglement of molecular chains, constructing a dense and uniform three-dimensional network structure. This invention effectively avoids microscopic particle residue and stress concentration, achieving a significant improvement in the tensile strength, elongation at break, and resilience of the toy adhesive.

The invention relates to the technical field of methylparaben synthesis, in particular to a synthetic method of methylparaben. The synthetic method of methylparaben comprises the following steps: taking p-hydroxybenzoic acid and methanol as raw materials, adding a catalyst material, carrying out heating treatment, and carrying out a heating reflux reaction; and after the methanol solution is distilled out, continuing to add methanol and carrying out a stirring reaction, repeating the steps, recovering the methanol solution for multiple times until the p-hydroxybenzoic acid is completely reacted, stopping the reaction, filtering, collecting filtrate, recovering the catalyst, distilling to remove methanol, and separating out crystals to prepare the methylparaben. The catalyst material comprises a strong acid cation exchange resin. According to the method, the strong acid type cation exchange resin is used as a catalyst, and water is distilled in the synthesis process, so that water in a reaction system is continuously removed, reaction equilibrium is continuously shifted rightwards, and the yield of methylparaben is increased. And the concentrations of methanol and the catalyst are almost unchanged in the later reaction stage, and the reaction rate is not affected.

The preparation method specifically comprises the following steps: step 1, adding 2-4 parts of sodium isostearoyl lactylate, 1-2 parts of propylene glycol, 1-2 parts of ethylene glycol, 1-3 parts of xanthan gum, 1-3 parts of carboxymethyl cellulose and 15-25 parts of lecithin into an oil phase pot, stirring and heating, and uniformly mixing to obtain an oil phase; 2, 1-3 parts of collagen, 1-3 parts of ceramide, 1-3 parts of hyaluronic acid, 5-10 parts of bamboo charcoal adsorption nano silver and 20-30 parts of deionized water are added into a water phase pot, heating and heat preservation are conducted, and uniform stirring is conducted to obtain a water phase; 3, adding the oil phase and the water phase into an emulsifying pot, heating, stirring and homogenizing; and step 4, reducing the temperature in the emulsifying pot, adding 25-35 parts of compound essential oil nanocapsules, 0.5-1 part of phenoxyethanol and 0.5-1 part of methylparaben, uniformly stirring and mixing, and cooling to obtain the acne-removing moisturizing lotion.

The present invention provides a toad oil cream and a preparation method thereof, and relates to the field of medical technology. The cream comprises toad oil and a matrix, wherein the toad oil is prepared according to the method of Chinese invention patent application CN117126696 A, and the matrix comprises phase A, phase B and phase C, wherein the phase A comprises: cetostearyl alcohol, glyceryl monostearate, liquid paraffin, dimethyl silicone oil and propylparaben, the phase B comprises: carbomer, glycerol, potassium lauryl phosphate, hyaluronic acid, methylparaben and water, and the phase C comprises the component triethanolamine. By optimizing the matrix, the cream obtained by the present invention has moderate hardness and softness, low cost, good coating property, uniformity and stability, and at the same time, the toad oil is turned into treasure.

The invention belongs to the technical field of pharmaceutical preparations, and provides a compound emulsifiable paste for inhibiting bacteria, relieving itching, diminishing inflammation and detoxifying and a preparation method of the compound emulsifiable paste. The compound cream is prepared from a water-phase raw material and an oil-phase raw material, the water-phase raw materials comprise ultramicro licorice powder, ultramicro alum powder, ultramicro mint powder, ultramicro borneol powder, glycerol, 1, 3-propylene glycol and xanthan gum; the oil phase raw materials comprise vegetable oil, vitamin E, methylparaben and vaseline. The compound emulsifiable paste has excellent effects of diminishing inflammation, relieving itching, inhibiting bacteria and detoxifying, has the characteristic of quick effect, and has a good treatment effect on mosquito bites (especially poisonous insect bites) and eczema; meanwhile, through compounding of specific auxiliary materials, the stability is further improved, and the storage life is effectively prolonged.