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37 results about "Methylparaben" patented technology

Methylparaben, also methyl paraben, one of the parabens, is a preservative with the chemical formula CH₃(C₆H₄(OH)COO). It is the methyl ester of p-hydroxybenzoic acid.

Recombinant collagen III and application thereof in preparation of gel

The invention relates to the technical field of biology, and particularly discloses a recombinant collagen III and application thereof in preparation of gel. The recombinant collagen III is designed by optimizing functional area sequences of human I-type and III-type collagen, the amino acid sequence is shown as SEQ ID No.2, and the recombinant collagen III has the characteristics of high stability, good hydrophilicity and low immunogenicity. The preparation method comprises the steps of expression vector construction, escherichia coli induced expression, affinity chromatography purification and renaturation. The recombinant collagen III can be prepared into a gel dressing and comprises sodium alginate, methylparaben and other components. Experiments show that the gel can effectively promote cell proliferation and has no cytotoxicity; in a mouse skin injury model, the collagen can relieve inflammation, accelerate wound healing and inhibit scar formation, and the effect of the collagen is superior to that of natural human III-type collagen. The invention provides a safe and efficient novel material for wound repair, and is suitable for medical dressings and tissue engineering.
Owner:GUANGXI XIEJIAN BIOTECHNOLOGY CO LTD

Method for immobilizing carbon dioxide

To provide a method for fixing carbon dioxide by which bubbles of carbon dioxide introduced into a solution can be made fine without increasing energy consumption.SOLUTION: A carbon dioxide fixation method comprising a precipitation step of introducing a gas containing carbon dioxide into a carbon dioxide fixation solution in which calcium ions are eluted to generate bubbles of the gas containing carbon dioxide in the carbon dioxide fixation solution, thereby reacting the calcium ions eluted in the carbon dioxide fixation solution with carbon dioxide to precipitate calcium carbonate, wherein the carbon dioxide fixation solution is an aqueous solution in which calcium ions are eluted in an aqueous solution of methylparaben.SELECTED DRAWING: Figure 1
Owner:AISIN CORP

Cream for repairing radiodermatitis and preparation method thereof

The invention relates to cream for repairing radiodermatitis and a preparation method of the cream, and belongs to the technical field of biomedical skin treatment. The cream consists of the following components in percentage by weight: 8% of glycerin monostearate, 6% of stearic acid, 5% of white vaseline, 4% of liquid wax, 1-2% of tea tree oil, 1-2% of eugenol, 1-2% of vitamin E, 3% of trehalose, 8% of polyethylene glycol (PEG-400), 10% of glycerol, 0.5% of methylparaben, 1% of triethanolamine and the balance of purified water. According to the cream disclosed by the invention, the natural traditional Chinese medicine component eugenol and the natural substance vitamin E are utilized to synergistically enhance the anti-oxidation and bacteriostatic effects, and the tea tree oil, the trehalose and other effective components are utilized to repair radiodermatitis from multiple aspects of anti-inflammation, bacteriostasis, antioxidation, promotion of skin barrier repair and the like. The cream is simple in component, good in treatment effect, high in safety and convenient to produce and process, and can be popularized and applied to treatment of radiodermatitis.
Owner:CHONGQING UNIV

Feed for artificial feeding of teak camel moths and artificial feeding method of teak camel moths

The invention provides a teak camel moth artificial feeding feed and a teak camel moth artificial feeding method, the feed comprises the following components by weight: 8% of wheat germ powder, 4% of soybean meal, 4% of yeast powder, 2% of casein, 2% of sucrose, 1.8% of agar powder, 1.5% of cellulose, 0.8% of Webster salt, 0.6% of vitamin C, 0.2% of sorbic acid, 0.3% of methyl p-hydroxybenzoate, 0.1% of cholesterol, 0.1% of choline chloride, 0.05% of inositol, 0.01% of folic acid, and the balance of water. And the balance of deionized water. The invention further provides an artificial feeding method of teak camelmoths, and the artificial feeding method comprises the steps of 1, adult mating and egg laying, 2, egg disinfection and incubation and 3, larva rearing. The feed does not contain host material teak leaves, and full-artificial continuous large-scale feeding of the teak camelmoths can be achieved.
Owner:INST OF FOREST ECOLOGY ENVIRONMENT & PROTECTION CHINESE ACAD OF FORESTRY

Atomoxetine hydrochloride oral suspension and use thereof

An oral liquid suspension comprising atomoxetine or a pharmaceutically acceptable salt thereof is disclosed, formulated at a concentration of about 20 mg / mL for the treatment of attention-deficit / hyperactivity disorder (ADHD). The suspension includes a dual preservative system (methylparaben and sodium benzoate), sweeteners, pH buffers, suspending agents, co-solvents, flavorants, and colorants. The composition demonstrates bioequivalence to Strattera® capsules, robust antimicrobial efficacy meeting USP <51> criteria, and physicochemical stability over 24 months in validated high-density polyethylene containers with child-resistant closures. The 20 mg / mL concentration enables precise dose titration for pediatric and dysphagic patients. Palatability is optimized through validated flavor masking studies, supporting high patient adherence. The invention further provides scalable manufacturing methods, quality control specifications, and methods of use for treating ADHD, offering a stable, safe, and patient-friendly alternative to solid oral dosage forms.
Owner:OWP PHARMACEUTICALS INC

Preparation method of medical recombinant collagen repair liquid

The invention discloses a medical recombinant collagen repair liquid preparation method, which is prepared from the following raw materials by weight: 1-100 g of recombinant collagen, 1-100 g of sodium hyaluronate, 1-100 g of glycerol, 1-100 g of purified water, and 1-10 g of methylparaben. The medical recombinant collagen repair liquid can effectively repair skin barriers and treat skin injuries caused by multiple reasons such as burns, wounds and laser postoperations, and meanwhile, the medical recombinant collagen repair liquid has remarkable advantages in the fields of gynecological inflammation treatment, private anti-aging, micro-ecological balance maintenance, wound healing promotion, tissue elasticity and compactness improvement and the like. Adverse reactions such as allergy are effectively reduced, and the requirements of people for high efficiency and safety of skin repairing products are met.
Owner:HENAN XIAOHULU BIOTECHNOLOGY CO LTD

A long-lasting antibacterial deodorant for sewage and preparation method thereof

The present invention relates to the field of sewage treatment technology, and more particularly to a long-lasting antibacterial deodorant for sewage and a preparation method thereof. The long-lasting antibacterial deodorant for sewage is prepared from raw materials comprising the following components in parts by weight: 0.2-0.3 parts of 1,2-benzisothiazolin-3-one, 0.3-0.5 parts of p-tert-amylphenol, 0.1-0.2 parts of methyl parahydroxybenzoate, 4-6 parts of activated carbon, 4-6 parts of modified sustained-release microspheres, 8-12 parts of a modified polymer, and 2-3 parts of modified lysozyme.
Owner:TIANJIN KEWEIJINHONG ENVIRONMENTAL PROTECTION SCI & TECH CO LTD

A method for preparing a brivaracetam solution and a brivaracetam solution

The present application discloses a method for preparing a brivaracetam solution and the brivaracetam solution thereof, belonging to the field of medical technology. The method for preparing the brivaracetam solution comprises the following steps: (1) preparing solution 1: mixing a mixture including sodium carboxymethylcellulose and glycerol with purified water and stirring to obtain solution 1; (2) preparing solution 2: mixing purified water, methylparaben, sodium malate, malic acid, sucralose, crystalline sorbitol solution, brivaracetam, and glycerol and stirring to obtain an intermediate solution, mixing the intermediate solution with essence and stirring to obtain solution 2; (3) mixing solution 1, solution 2 and purified water, stirring, and filtering to obtain a brivaracetam solution. The method improves the clarity of the solution by controlling the order and temperature of addition of each auxiliary material, and the obtained brivaracetam solution has good stability and is free of precipitation and degradation impurities.
Owner:HAINAN WEI KANG PHARMA QIANSHAN

Enhancer of nucleic acid amplification

The disclosure relates to methods for amplifying a target nucleic acid. The methods include performing an amplifying step comprising contacting the nucleic acid with a polymerase, dNTPs, one or more set of primers specific for the nucleic acid, and an amplification enhancer that is methyl paraben or a derivative thereof. Also described are kits and reaction mixtures for the amplification of a target nucleic acid in the presence of the amplification enhancer, as well as methods for enhancing nucleic acid amplification.
Owner:ROCHE DIAGNOSTICS GMBH +1

Compound lithospermum lip balm for improving chronic cheilitis as well as preparation method and application of compound lithospermum lip balm

PendingCN121196985ACosmetic preparationsDigestive systemCommiphora myrrha resinAngelica Sinensis Root
The invention provides a compound lithospermum erythrorhizon lip balm for improving chronic cheilitis, which is characterized by being prepared by adding methylparaben into the following raw materials: 6g of lithospermum erythrorhizon, 1g of angelica sinensis, 1g of divaricate saposhnikovia root, 1g of radix rehmanniae recen, 1g of liquorice, 1g of radix angelicae, 1g of frankincense, 1g of myrrh, 0.01 g of methylparaben, 0.1 g of vitamin E, 30g of beewax and 150mL of olive oil. The preparation method comprises the following steps: mixing Chinese angelica, divaricate saposhnikovia root, raw rehmannia root, licorice, dahurian angelica root, frankincense and myrrh, frying with olive oil to obtain medicinal oil A, adding lithospermum, heating, filtering, cooling the obtained medicinal oil B to 60 DEG C, adding vitamin E to obtain medicinal oil C, adding heated and melted beeswax, uniformly mixing, adding methylparaben, and pouring. The invention further provides application, and the prepared compound lithospermum erythrorhizon lip balm is used for improving chronic cheilitis. The compound lithospermum erythrorhizon lip balm for improving chronic cheilitis prepared by the invention can be used for improving chronic cheilitis, is safe and effective, and can relieve lip symptoms of chronic cheilitis.
Owner:承德护理职业学院

Whitening facial cleanser and preparation method thereof

PendingCN121313507ACosmetic preparationsToilet preparationsOLEAMIDOPROPYL BETAINESodium Lauryl Sarcosinate
The invention discloses a whitening facial cleanser and a preparation method thereof, and relates to the field of skin care products. The whitening facial cleanser is prepared from 35 to 42 weight percent of a cleaning agent, 1 to 2 weight percent of a whitening and freckle-removing agent, 0.8 to 1.2 weight percent of a skin conditioner, 4 to 8 weight percent of an emollient, 4 to 6 weight percent of a humectant, 0.3 to 0.5 weight percent of a preservative, 0.05 to 0.1 weight percent of a chelating agent, 4 to 4.5 weight percent of a thickening agent, 0.2 to 0.5 weight percent of an aromatic, 0.8 to 1.0 weight percent of a pH regulator and the balance of a solvent. The cleaning agent is prepared from sodium lauroyl isethionate, sodium cocoyl aminopropionate, cocamidopropyl betaine and sodium lauroyl sarcosinate according to the weight ratio of (3.5 to 4.5) to 1 to 1 to 1; the preservative comprises DMDM hydantoin and methylparaben in a weight ratio of (3-4): 1. The whitening facial cleanser provided by the invention has both cleaning power and mildness, and also has a whitening effect.
Owner:ZHAOQING QIAOQIAO DAILY CHEM CO LTD

Atomoxetine hydrochloride oral suspension and use thereof

An oral liquid suspension comprising atomoxetine or a pharmaceutically acceptable salt thereof is disclosed, formulated at a concentration of about 20 mg / mL for the treatment of attention-deficit / hyperactivity disorder (ADHD). The suspension includes a dual preservative system (methylparaben and sodium benzoate), sweeteners, pH buffers, suspending agents, co-solvents, flavorants, and colorants. The composition demonstrates bioequivalence to Strattera® capsules, robust antimicrobial efficacy meeting USP <51> criteria, and physicochemical stability over 24 months in validated high-density polyethylene containers with child-resistant closures. The 20 mg / mL concentration enables precise dose titration for pediatric and dysphagic patients. Palatability is optimized through validated flavor masking studies, supporting high patient adherence. The invention further provides scalable manufacturing methods, quality control specifications, and methods of use for treating ADHD, offering a stable, safe, and patient-friendly alternative to solid oral dosage forms.
Owner:OWP PHARMACEUTICALS INC

HPLC (High Performance Liquid Chromatography) detection method of adapalene gel and application thereof

The invention provides an HPLC (High Performance Liquid Chromatography) detection method of adapalene gel and application thereof, and particularly relates to the technical field of analysis and detection of medicinal components. The HPLC detection method of the adapalene gel is used for simultaneously detecting the contents of adapalene, methylparaben and phenoxyethanol in the adapalene gel; according to the HPLC detection method, a mixed solution of a mobile phase A and a mobile phase B is used as a mobile phase, and a sample solution to be detected is subjected to gradient elution; the initial volume ratio of the mobile phase A to the mobile phase B is (78-82): (22-18); in the gradient elution, the volume ratio of the mobile phase A to the mobile phase B is from (78-82): (22-18) to (28-32): (72-68) and finally returns to (78-82): (22-18). The detection method is simple and can be used for simultaneously determining the contents of adapalene, methylparaben and phenoxyethanol.
Owner:BEIJING JINGFENG PHARMA GRP +2

A method for making toy glue

This invention relates to the fields of fine chemicals and polymer materials technology, specifically a method for manufacturing toy adhesives. It includes steps for preparing the adhesive base material, preparing borax solution, and cross-linking molding. Polyvinyl alcohol, guar gum, methylparaben, etc., are prepared as base materials, which are then reacted with borax solution to undergo a cross-linking reaction. The core of this invention is the strict limitation of specific high-temperature ranges and constant-temperature stirring times during the base material preparation process, which promotes the complete extension and entanglement of molecular chains, constructing a dense and uniform three-dimensional network structure. This invention effectively avoids microscopic particle residue and stress concentration, achieving a significant improvement in the tensile strength, elongation at break, and resilience of the toy adhesive.
Owner:ZHEJIANG SHENGBOAO TRADE LTD CO

Compound emulsifiable paste for inhibiting bacteria, relieving itching, diminishing inflammation and detoxifying and preparation method of compound emulsifiable paste

The invention belongs to the technical field of pharmaceutical preparations, and provides a compound emulsifiable paste for inhibiting bacteria, relieving itching, diminishing inflammation and detoxifying and a preparation method of the compound emulsifiable paste. The compound cream is prepared from a water-phase raw material and an oil-phase raw material, the water-phase raw materials comprise ultramicro licorice powder, ultramicro alum powder, ultramicro mint powder, ultramicro borneol powder, glycerol, 1, 3-propylene glycol and xanthan gum; the oil phase raw materials comprise vegetable oil, vitamin E, methylparaben and vaseline. The compound emulsifiable paste has excellent effects of diminishing inflammation, relieving itching, inhibiting bacteria and detoxifying, has the characteristic of quick effect, and has a good treatment effect on mosquito bites (especially poisonous insect bites) and eczema; meanwhile, through compounding of specific auxiliary materials, the stability is further improved, and the storage life is effectively prolonged.
Owner:ZESHI RUNKANG (BEIJING) MEDICAL TECH CO LTD

Hair care and conditioning wheat compositions, cosmetic products containing the same and methods of making

PendingCN122297317ABiotechnologyGlycerol
This application relates to the technical field of daily cosmetics, specifically disclosing a hair-repairing and conditioning wheat composition, a cosmetic containing the composition, and a preparation method thereof. The hair-repairing and conditioning composition comprises the following components in parts by weight: 0.003-0.006 parts of a mixture of hydrolyzed wheat protein / phenoxyethanol / methylparaben / ethylparaben / ethylhexylglycerin / propylene glycol / water; 0.03-0.05 parts of a mixture of wheat germ oil glycerides / glyceryl stearate; and 2.4-2.6 parts of a mixture of cationic surfactant / ethanol. The wheat germ oil glycerides selected in this application are rich in linoleic acid and vitamin E, exhibiting a stronger affinity for cationic surfactants, enabling the formation of a stable "cationic-oil complex" for efficient deposition. Simultaneously, the wheat germ oil glycerides are homologous to hydrolyzed wheat protein, forming a synergistic repair mechanism of first penetrating and filling, then sealing and locking in moisture, thus improving the hair-repairing and conditioning effect.
Owner:SHANGHAI ZHANGHUA HEALTH COSMETICS CO LTD

Zinc oxide foam and preparation method thereof

The present invention relates to the technical field of zinc oxide foam, and a kind of zinc oxide foam and preparation method thereof is provided.The zinc oxide foam comprises the following raw materials: isobutane, zinc oxide, 1,2-butylene glycol, polydimethylsiloxane, caprylic acid / capric acid triglyceride, steareth-21, cetearyl alcohol, glycerol, D-panthenol, sunflower seed oil, propane, steareth-2, hydroxypropyl methylcellulose, parahydroxyacetophenone, 1,2-hexanediol, 1,3-propylene glycol, marigold extract, phenoxyethanol, methylparaben and water.The zinc oxide foam of the present invention has lower foam density and higher foam stability, has good ultraviolet protection effect, and can absorb skin grease, regulate skin microenvironment, and contribute to wound healing.At the same time, due to the characteristics of its foam formulation, it can be easy to use, evenly distributed, will not leave obvious white residue on the skin, and provides a pleasant sensory experience.
Owner:WUXI ZHIYAN BIOTECHNOLOGY CO LTD

Methanol recovery tank for methylparaben production

The utility model discloses a methanol recovery tank for methylparaben production, which comprises a methanol recovery tank, a cleaning mechanism is arranged in the methanol recovery tank, the cleaning mechanism comprises a horizontal rotating shaft, the horizontal rotating shaft is driven by a second rotating motor to rotate, a plurality of cleaning brushes are arranged outside the second rotating motor, and the cleaning brushes are connected with the cleaning mechanism. Bristles are arranged on the side, away from the horizontal rotating shaft, of the cleaning brush, a distance adjusting mechanism is arranged between the cleaning brush and the horizontal rotating shaft, the distance adjusting mechanism comprises fixed supporting discs symmetrically arranged at the two ends of the horizontal rotating shaft, gear discs are arranged on the sides, close to each other, of the two fixed supporting discs, and the gear discs are rotationally installed outside the horizontal rotating shaft. According to the cleaning mechanism in the methanol recovery tank, the distance adjusting mechanism is arranged between the cleaning brush and the horizontal rotating shaft, and the distance between the cleaning brush and the horizontal rotating shaft can be adjusted according to the abrasion condition of the bristles, so that the bristles can continuously and effectively brush the inner wall of the methanol recovery tank, and the replacement frequency of the cleaning brush is reduced.
Owner:SUZHOU HENGCHANG BIOTECHNOLOGY CO LTD

Quinacridone pigment red surface treatment process based on high crystal transformation quality

PendingCN121873578AQuinacridonesBenzoic acidAcridine
The invention belongs to the technical field of pigment red preparation, and particularly provides a high crystal transformation quality-based quinacridone pigment red surface treatment process, which comprises the following steps: 1) taking a pigment crude product, and carrying out grinding and salt milling to obtain a primary treatment material; and 2) adding a solvent and a MA-HBA derivative into the primary treatment material, stirring for pigmentation, and then filtering and drying to obtain the pigment red, the MA-HBA derivative is prepared by synthesizing methyl p-hydroxybenzoate and 1, 11-undecanediol, and the prepared pigment red has the advantages of good pigmentation effect and good covering power.
Owner:ZHEJIANG EUCHEM CHEM

A composition for treating dysmenorrhea caused by cold uterus and relieving menstrual pain, and its preparation method thereof.

PendingCN122124150AAntipyreticAnalgesicsUterine musclesMyrrh
This invention provides a composition for treating dysmenorrhea due to cold in the uterus and relieving menstrual pain, and its preparation method, relating to the field of traditional Chinese medicine composition technology. The raw materials of this composition are: bergamot, oldenlandia diffusa, broom flower, evening primrose-morinda officinalis extract, mugwort, chuanxiong rhizome, angelica sinensis, astragalus, frankincense, myrrh, madder root, licorice, prepared rehmannia root, dried ginger, eucommia bark, peach kernel, safflower, Tween-80, sodium carboxymethyl cellulose, propylene glycol, methylparaben, and water. Through the synergistic effect of each component, it can regulate uterine smooth muscle contraction, relieve uterine smooth muscle spasms, improve blood rheology, effectively improve uterine microcirculation, help expel stagnant blood from the uterine cavity, and relieve menstrual pain. It has the effects of promoting blood circulation, removing blood stasis, regulating menstruation, relieving pain, replenishing qi and nourishing, and warming the middle jiao and dispelling cold, thus it can be used to treat dysmenorrhea due to cold in the uterus and relieve menstrual pain.
Owner:GUANGZHOU HUAXIA BIOPHARMACEUTICALS CO LTD +2

Medical skin repair dressing and preparation method thereof

The invention provides a medical skin repair dressing and a preparation method thereof, and relates to the technical field of medical skin repair, the medical skin repair dressing comprises 0.8%-0.1% of collagen, 5% of glycerin, 0.15% of methylparaben, 0.75% of hydroxyethyl cellulose, 0.01% of a flavoring agent, and 93.29%-93.99% of pure water, the pH value of the medical skin repair dressing is 5.5-7.0, and the medical skin repair dressing is prepared from the following components in percentage by weight: 0.8%-0.1% of collagen, 5% of glycerin, 0.15% of methylparaben, 0.75% of hydroxyethyl cellulose, 0.01% of a flavoring agent, and 93.29%-93.99% of pure water. And the viscosity of the medical skin repair dressing is 15 Pa.s to 30 Pa.s. The invention has the following advantages: collagen as a natural biopolymer has good biocompatibility and biodegradability, can promote cell adhesion and proliferation, and plays a key role in skin repair; glycerin has excellent moisturizing performance, can form a layer of moisturizing film on the surface of a wound surface, maintains a moist environment of the wound, and is beneficial to cell viability and wound healing; as a common preservative, methylparaben can effectively inhibit the growth of microorganisms and ensure the safety and stability of the dressing; and the flavoring agent can improve the smell of the dressing and improve the comfort level of the patient.
Owner:GUODA PHARMACEUTICAL (TIANJIN) CO LTD

Intelligent medical coupling agent as well as preparation method and application thereof

The invention discloses an intelligent medical coupling agent as well as a preparation method and application thereof, and belongs to the technical field of medical materials. Comprising the following steps: dissolving SiO2 nanoparticles in deionized water, adding an HPTS dye and gamma-aminopropyltriethoxysilane, purifying and concentrating to obtain a pH response nanoprobe; the preparation method comprises the following steps: dissolving dipalmitoyl phosphatidylcholine, dipalmitoyl phosphatidyl glycerol and a therapeutic drug in a chloroform-methanol mixed solvent, and evaporating and drying to obtain a lipid film; adding a PBS (Phosphate Buffer Solution) into the lipid film, introducing perfluoropropane, carrying out rotary shearing emulsification, and collecting micro-bubbles to obtain drug-loaded ultrasonic response micro-bubbles; the preparation method comprises the following steps: adding the carbomer powder into deionized water, and then adding glycerol, triethanolamine and methylparaben to obtain basic gel; adding a pH response nanoprobe into the basic gel, adding drug-loaded ultrasonic response microbubbles after the fluorescence intensity CV value is less than or equal to 5%, and performing multi-stage gradient vacuum treatment to obtain the intelligent medical coupling agent. The intelligent medical coupling agent provided by the invention realizes targeted delivery of drugs and physiological status feedback of tissues.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Application of recombinant human glaze matrix protein in anti-periodontitis oral care product

PendingCN122075334ACosmetic preparationsAntibacterial agentsPeriodontal pathogenToothpaste
The invention discloses application of recombinant human glaze matrix protein in preparation of an anti-periodontitis oral care product. The oral care product is prepared from rhEMPs, glycerin, sorbitol, poloxamer 188, sodium lauroyl sarcosinate, potassium nitrate, sucralose, xylitol, methylparaben, propylene glycol, PEG-40 hydrogenated castor oil, domiphen and water. The core innovation of the oral care product is that the stability bottleneck of rhEMPs in the physiological pH environment of the oral care product is solved by utilizing the synergistic stabilization effect of poloxamer 188 and sodium lauroyl sarcosinate, and it is found that when the oral care product is combined with components such as potassium nitrate, periodontal pathogenic bacteria can be remarkably inhibited, gingival inflammation can be relieved, and periodontal tissue repair can be promoted. The product form can be mouth wash, oral spray or toothpaste, the preparation process is simple, the stability is good, and a brand new solution is provided for daily adjuvant therapy of periodontitis.
Owner:GUANGZHOU XUELIANG BIOTECHNOLOGY DEVELOPING CO LTD

Anti-wrinkle, whitening and freckle-removing skin care product and preparation method thereof

The invention provides an anti-wrinkle, whitening and freckle-removing skin care product and a preparation method thereof, and belongs to the technical field of cosmetics. The skin care product comprises the following components: a phase A: shea butter, simmondsia chinensis seed oil, tocopherol, cetostearyl alcohol, isooctyl palmitate, squalane and polyglycerol-3 methyl glucose distearate; the phase B is prepared from glycerol, 1, 2-hexanediol, sodium ascorbate phosphate and disodium ethylene diamine tetraacetate; a phase C: pterostilbene, nicotinamide, an ethyl ferulate compound, a ginseng extract and a sea-buckthorn extract; phase D: methylparaben and a stabilizer; and the balance of deionized water. Through the synergistic effect of the raw materials, the prepared skin care product not only has the effects of removing wrinkles, whitening and removing freckles, but also is good in stability and high in safety.
Owner:SHANDONG KANGYUAN RUITONG TECHNOLOGY DEVELOPMENT CO LTD

Composition for inhibiting bacteria and freshening breath and preparation method thereof

PendingCN120531648ACosmetic preparationsToilet preparationsBiotechnologyEthylhexyl palmitate
The invention discloses a composition capable of inhibiting bacteria and freshening breath and a preparation method of the composition. Comprising the following components in percentage by mass: 1%-2% of mint, 0.05%-0.1% of domiphen, 0.1%-0.3% of citric acid, 5%-10% of xylitol, 0.1%-0.5% of essence, 0.01%-0.05% of beta-glucanase, 0.05%-0.3% of tocopherol, 0.1%-0.3% of melaleuca alternifolia, 0.05%-0.1% of methylparaben, 1%-2% of ethylhexyl palmitate, 8% of coconut oil, 0.01%-0.05% of saccharin sodium salt, 0.5%-1.5% of PEG-40 hydrogenated castor oil and the balance of water. By adopting the method, water and oil can be layered, the upper layer is preferably selected from plant essential oil, and the lower layer is prepared from water-based antibacterial components; the invention aims to maintain the activity of essential oil, effectively reduce harmful flora in the oral cavity through the aqueous component, maintain the oral health and realize the effect of freshening breath.
Owner:SHENZHEN SIMIPAI TECHNOLOGY CO LTD

ANTIBACTERIAL GEL FROM THE ACTIVE INGREDIENT OF PISTACHIO SHELL EXTRACT

PendingIDS00202607833ABiotechnologyBenzoic acid
This invention relates to a gel preparation with pistachio shell extract as the active ingredient which has the effect of inhibiting Staphylococcus aureus bacteria. The gel consists of pistachio shell extract made from a maceration process using 70% alcohol, 5% CMC-Na gel base, 5.0% glycerin humectant, 3.0% propylene glycol, 0.25% methyl paraben preservative and aquades solvent added up to 100%. The gel has antibacterial activity which is characterized by the formation of an inhibition zone against Staphylococcus aureus bacteria. The emergence of this inhibition zone is due to the active compound contained in the gel base diffusing through the media so that it is able to inhibit the growth of Staphylococcus aureus bacteria. The positive control used in this antibacterial test is 1.2% clindamycin phosphate gel.From the results of the antibacterial effectiveness test that has been carried out, it was found that 10% to 25% pistachio shell extract gel can inhibit ≥15mm-24mm of Staphylococcus aureus bacterial growth with Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values ​​of 80% and 100%, respectively.
Owner:HEKA MARETA NUGRAHENI +1

A cream of desonide and a method of preparing the same

The application relates to a desonide cream and a preparation method thereof. The composition of raw materials for preparing the desonide cream, with 100 g of the desonide cream as a unit, is as follows: 0.04-0.06 g of desonide, 10.0-14.0 g of cetearyl alcohol, 1.0-3.0 g of synthetic beeswax, 0.1-7.0 g of light liquid paraffin, 1.0-20.0 g of white vaseline, 4.0-6.0 g of glycerol, 1.5-2.5 g of sodium lauryl sulfate, 0.04-0.06 g of aluminum sulfate, 0.04-0.06 g of calcium acetate, 0.1-0.2 g of methylparaben, 0.01-0.02 g of dextrin, and the rest of water. The application optimizes the content of each raw material component in the desonide cream and improves the preparation process, so that the in-vitro release and transdermal behavior of the desonide cream are consistent with those of a reference preparation, the product quality is more stable, and the application prospect is good.
Owner:HANGZHOU MINSHENG PHARM CO LTD

A small line angle of the wood borer larva artificial feed and its preparation method and application

The present application belongs to the technical field of insect feeding, and provides a kind of artificial feed for small line angle wood borer larvae, and its preparation method and application.The artificial feeding special feed includes the following raw materials by weight: white waxwood shavings 90-110 parts, soybean powder 25-35 parts, corn flour 10-20 parts, agar powder 3-7 parts, sucrose 2-4 parts, yeast powder 2-4 parts, cholesterol 0.3-0.7 parts, potassium sorbate 0.3-0.7 parts, methyl paraben 0.3-0.7 parts, ascorbic acid 0.3-0.7 parts, soybean oil 3-7 parts, and water 90-110 parts.Through three months of feeding test, it is proved that the growth rate and weight gain of group B larvae are significantly better than those of other groups, and the growth state of the experimental group with added oil and fat is obviously better, which provides an efficient technical solution for the large-scale artificial feeding of small line angle wood borer larvae, and provides a stable insect source for related biological research and prevention and control technology development.
Owner:HEBEI AGRICULTURAL UNIV.

Minoxidil external preparation and preparation method thereof

The invention relates to a preparation method of a minoxidil external preparation. The preparation method comprises the following steps: preparing an extract from raw materials of ginger, purslane, cacumen biotae and polygonum multiflorum; stearic acid, liquid paraffin, glyceryl monostearate and cetostearyl alcohol are mixed and heated to obtain an oil phase; carbomer 940 is dispersed in purified water, glycerin, poloxamer 188 and methylparaben are added, and a water phase is prepared; and adding the oil phase into the water phase, homogenizing and emulsifying to obtain a matrix, adding minoxidil and the extract into the matrix, and treating by a pulsed electric field to obtain the cream preparation. According to the minoxidil emulsifiable paste preparation prepared by the invention, the use of irritant components such as ethanol and propylene glycol is reduced, the emulsifiable paste is excellent in stability, minoxidil is excellently dispersed in the emulsifiable paste and is not agglomerated, the long-term stability of active components is good, and the traditional Chinese medicine active components and minoxidil have a synergistic effect, so that the minoxidil emulsifiable paste preparation has excellent permeability and can be used for preparing the minoxidil emulsifiable paste preparation. The effects of conditioning, relieving and repairing the scalp are jointly improved, the effect on hair follicles is effectively promoted, and the growth period of the hair follicles is prolonged.
Owner:CHONGQING CONQUER PHARML

Analgesic ointment and preparation method thereof

ActiveCN117442656BAntipyreticAnalgesicsMenthoneGlycerol
The present invention belongs to the technical field of compositions and discloses an analgesic ointment and its preparation method. The analgesic ointment comprises: Component A: a thickener, methylparaben, and water; Component B: an emulsifier, menthyl lactate, and menthol; Component C: a neutralizer, panthenol, white willow bark extract, and water; and Component D: phenoxyethanol, menthone glycerol ketal, CTR50, and water. The preparation method comprises: preparing CTR50; adding the thickener and methylparaben to water and mixing to obtain Component A; adding the materials in Component B to Component A to obtain a mixed material; sequentially adding the white willow bark extract, the neutralizer, and panthenol dissolved in water by heating to the mixed material; and finally adding the materials in Component D and mixing to obtain the ointment. The present invention incorporates Corydalis root extract into the analgesic ointment in the form of CTR50, compounding it with the other components. This provides the ointment with the ability to relieve labor pains while maintaining its stability, and can alleviate symptoms such as various strains, sprains, and lumbar muscle strain.
Owner:GUANGZHOU MASHANGHUI BIOTECHNOLOGY CO LTD