The invention relates to the field of lipidosome technology and
skin external preparations, in particular to bionic
ceramide coated
retinol lipidosome and a preparation method and application of the bionic
ceramide coated
retinol lipidosome. The
liposome is prepared from the following raw materials in parts by weight: 1.0 to 3.0 weight percent of
ceramide NP, 1.0 to 3.0 weight percent of
ceramide AP, 0.05 to 0.5 weight percent of ceramide EOP, 1.0 to 3.0 weight percent of
cholesterol, 0.50 to 2.0 weight percent of
meadowfoam seed oil, 3.0 to 10.0 weight percent of hydrogenated
lecithin, 1.0 to 3.0 weight percent of
retinol, 0.50 to 2.50 weight percent of
tocopheryl acetate, 15.0 to 45.0 weight percent of caprylic / capric
triglyceride MCT, 1.0 to 5.0 weight percent of
propylene glycol, 15.0 to 45.0 weight percent of
glycerol and the balance of water, the bionic layered film is constructed by the multi-subtype ceramide,
cholesterol and hydrogenated
lecithin, the
oil phase and an
antioxidant system are cooperated, the stability of retinol under light, heat and
oxygen is remarkably improved, slow release is achieved, meanwhile,
skin tolerance is improved, and the bionic layered film can be widely applied to essence,
emulsion, face cream,
ampoule and other external
skin care preparations.