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1198 results about "Glucoside" patented technology

A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes.

Plant lactobacillus XD117, application of plant lactobacillus XD117 in fermentation of astragalus membranaceus, astragalus membranaceus fermentation product and preparation method of astragalus membranaceus fermentation product

The invention belongs to the technical field of microbial fermentation, and particularly relates to a plant lactobacillus XD117, application of the plant lactobacillus XD117 in fermentation of astragalus membranaceus, an astragalus membranaceus fermentation product and a preparation method of the astragalus membranaceus fermentation product. The bacterial strain is lactobacillus plantarum XD117 and is preserved in the China Center for Type Culture Collection, and the preservation number of the bacterial strain is CCTCC NO: M 20241730. The preparation method of the astragalus mongholicus fermentation product comprises the following steps: inoculating the lactobacillus plantarum XD117 into astragalus mongholicus enzymatic hydrolysate, and fermenting in a fermentation temperature range suitable for the lactobacillus plantarum XD117 to obtain the astragalus mongholicus fermentation product. The total content of calycosin, formononetin, calycosin glucoside and formononin in the astragalus mongholicus fermentation product is high, and the astragalus mongholicus fermentation product has a very good antioxidant effect.
Owner:江苏菌钥生命科技发展有限公司 +1

Method for improving anti-aging effect of eurotium cristatum tea compound fermentation liquor

The invention provides a technical method for improving the anti-aging effect of eurotium cristatum tea compound fermentation liquor, and belongs to the technical field of microorganisms, the Latin name of eurotium cristatum is Eurotium cristatum, the eurotium cristatum is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC M 2024643. According to the method, the yeast seed solution is inoculated into the tea-sea buckthorn leaf culture solution fermented by the eurotium cristatum, so that the content of anti-aging active components such as procyanidine B2, quercitrin, cyanidin-3-glucoside, nicotinic acid, naringenin and rutin in the fermentation culture solution can be remarkably increased through co-fermentation, and the elastase inhibition rate can be remarkably increased; the anti-aging effect of a component system of the fermentation culture solution is enhanced. The prepared tea-hippophae rhamnoides leaf compound fermentation liquor is suitable for development of anti-aging cosmetics and has a wide market prospect.
Owner:GUANGZHOU ZHONGZHUANG BEAUTY COSMETICS CO LTD +1

Chinese herbal medicine preparation for preventing and controlling African swine fever and preparation method thereof

The invention provides a Chinese herbal medicine preparation for preventing and controlling African swine fever and a preparation method thereof. The Chinese herbal medicine preparation for preventing and controlling African swine fever provided by the invention comprises the following components in parts by weight: 4 parts of honeysuckle, 4 parts of fructus forsythiae, 5 parts of radix isatidis, 2 parts of astragalus membranaceus, 1 part of rhodiola rosea, 3 parts of anise, 0.5 part of roasted ephedra, 1 part of fried almond, 2 parts of gypsum, 2 parts of houttuynia cordata, 0.5 part of rheum officinale, 2 parts of rhizoma dryopteris crassirhizomae, 1 part of pogostemon cablin, 0.5 part of mint, 1 part of lalang grass rhizome, 1 part of dendrobe, 0.5 part of coptis chinensis and 0.5 part of liquorice. The Chinese herbal medicine preparation for preventing and controlling the African swine fever, provided by the invention, contains chlorogenic acid, luteoloside, calycosin-7-glucoside, forsythin, (R, S)-epigoitrin and aspimaric acid. And aspidin. And mongolic acid and the like. The composition has the functions of resisting viruses, resisting bacteria, improving immunity and the like. According to the Chinese herbal medicine preparation for preventing and controlling the African swine fever and the preparation method, provided by the invention, the African swine fever virus infection can be resisted, and the effect of promoting the rehabilitation of African swine fever virus recessive infected pigs is achieved.
Owner:HENAN PROVINCE ZHENGYANG BREEDING PIG FARM

Anti-wrinkle and anti-aging composition as well as preparation method and application thereof

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.
Owner:GUANGZHOU SUNLIFE BIOTECHNOLOGY CO LTD

Tocopherol glucoside and preparation process thereof

The invention belongs to the field of biological fermentation synthetic medicines, and particularly relates to tocopherol glucoside and a preparation process thereof. The synthesis method comprises the following steps: (1) preparing an enzyme catalyst; (2) carrying out enzymatic conversion reaction; (3) purifying ion resin; (4) removing impurities; the synthesis process provided by the invention is simple in route and strong in operability, the prepared tocopherol glucoside is high in purity, the total yield of the product is greater than 30%, and the purity is greater than 95.0%.
Owner:QINGDAO SANRENXING CHEM CO LTD +1

Application of citrus flavonoid glycosyl transferase CitUGT73A78 in biosynthesis of flavonoid glycoside

The invention provides an application of citrus flavonoid glycosyl transferase CitUGT73A78 in biosynthesis of flavonoid glycoside, and belongs to the technical field of gene engineering and enzyme engineering. According to the present invention, the function of the CitUGT73A78 gene is cloned and verified, and the in vitro enzyme activity test proves that the CitUGT73A78 recombinant protein has broad-spectrum catalytic activity, and can efficiently catalyze the glucosylation of a variety of flavonoids so as to generate the corresponding flavonoids 7-O-glucoside and / or flavonoids 4 '-O-glucoside. An in-vivo transient overexpression test also proves that the CitUGT73A78 gene has a promoting effect on the accumulation of the content of the citrus flavonoid 7-O-glucoside. The invention not only provides a preparation method for the production of flavonoid 4 '-O-glucoside, has the advantages of simplicity, convenience, high catalytic efficiency, low cost, greenness and safety, but also can be applied to nutritional quality improvement and germplasm innovation of citrus fruits.
Owner:ZHEJIANG UNIV

Acne-removing and relapse-preventing composition suitable for acne sensitive skin and application thereof

The invention provides an acne-removing and relapse-preventing composition suitable for acne sensitive skin and application of the acne-removing and relapse-preventing composition, and belongs to the technical field of cosmetics. The epigallocatechin gallic acid glucoside, the brazilin, the roselle flower extract, the jujube bark extract, the linseed oil unsaponifiable matter and the guaiacol extract are selected as active ingredients of the acne-removing and relapse-preventing composition and interact with one another, growth of acne-related pathogenic bacteria can be rapidly inhibited, and the skin micro-ecology can be adjusted; skin inflammation in the whole process of acne is effectively inhibited, the effects of preventing and inhibiting inflammation are achieved, the skin barrier is effectively repaired, redness is reduced, meanwhile, the effect of adjusting skin grease balance is achieved, and acne recurrence is prevented; in addition, the acne-removing and relapse-preventing composition also has the effects of removing yellow gas, uniformizing skin color and improving skin roughness, is mild and non-irritating, can be used for sensitive skin, and expands the application range of the acne-removing and relapse-preventing composition.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

New application of moss phenol glucoside

The invention belongs to the technical field of medicines, and particularly discloses application of moss phenol glucoside in preparation of medicines for preventing and / or treating tumors. According to the method, activated CD8 + T cells, MC38-OVA cells and traditional Chinese medicine monomeric compounds are co-cultured, the traditional Chinese medicine monomeric compounds capable of effectively promoting the anti-tumor activity of the CD8 + T cells are selected by utilizing a high-content screening technology, and finally, the experiment is carried out by taking the moss phenol glucoside as a research object. In-vitro experiment results show that the moss phenol glucoside can significantly promote T cell activation, promote release of cell factors such as IFN-gamma and TNF-alpha, and enhance the killing effect of T cells on tumors. A mouse in-vivo tumor-bearing experiment result shows that the moss phenol glucoside can promote the anti-tumor activity of T cells so as to inhibit tumor growth, has no obvious toxic or side effect, can be used for preparing the medicine for preventing and / or treating tumors, and has a potential clinical application prospect and a relatively high economic value.
Owner:ZHENGZHOU UNIV

Composition capable of resisting thermal stimulation and UV stimulation, application and cosmetics

The invention belongs to the field of cosmetics, and discloses a composition which comprises a pepper fruit extract, epigallocatechin gallyl glucoside, diacetylboldine, a sanguisorba officinalis root extract and nicotinamide. The composition is detected by a DPPH method to have an excellent antioxidant effect. Meanwhile, the invention also discloses a composition capable of resisting thermal stimulation and UV stimulation, which can obviously inhibit the lipofuscin generation level of nematodes after thermal stimulation and UV stimulation by adopting nematode model detection. And after the composition is used together with the withanolaria nipponensis root extract, the composition has a remarkable synergistic effect on inhibition of lipofuscin generation of nematodes subjected to thermal stimulation and ultraviolet light stimulation. The composition provided by the invention has very good anti-wrinkle effects of light aging resistance and thermal aging resistance, and can effectively prevent the generation of color spots.
Owner:GUANGDONG HEJI BIOTECH CO LTD

Anti-wrinkle composition containing recombinant collagen as well as preparation method and application of anti-wrinkle composition

The invention relates to the field of cosmetics, and discloses an anti-wrinkle composition containing recombinant collagen as well as a preparation method and application of the anti-wrinkle composition. The anti-wrinkle composition is prepared by compounding I-type collagen peptide nano-micelles, recombinant humanized III-type collagen, recombinant humanized XVII-type collagen, glycosylglycerol and ceramide. The skin care composition has the advantages that multiple synergistic effects are achieved, collagen generation is promoted, the skin moisturizing capacity is enhanced, and the skin barrier is repaired, so that the elasticity, compactness and smoothness of the skin are remarkably improved. The product disclosed by the invention has the effects of skin barrier repair, anti-aging care, collagen protection, collagen generation promotion, water locking and moisturizing and the like, and is suitable for research, development and application of skin care products for resisting wrinkles, tightening and delaying senescence.
Owner:GUANGZHOU KENENG COSMETICS RES CO LTD +1

Application of betulinic acid 28-O-beta-D-glucoside in preparation of medicine for preventing and treating skin inflammation

PendingCN120204242AOrganic active ingredientsNervous disorderPityriasis roseaPimple
The invention discloses an application of betulinic acid 28-O-beta-D-glucoside (BA-6 for short) in preparation of a medicine for preventing and treating skin inflammation. The problems that an existing medicine for treating dermatitis is limited in curative effect, slow in effect taking, multiple in side effect, high in long-term use risk, large in individual difference, high in treatment cost, likely to cause immunoreaction and the like are solved. The invention discloses application of BA-6 in prevention and treatment of atopic dermatitis, contact dermatitis, eczema, rash, psoriasis, lupus erythematosus, papule squamous skin disease, pityriasis rosea, seborrheic dermatitis, pemphigus, celestial abscess, acne, tinea corporis, impetigo, SAPHO syndrome, hidradenitis suppurativa, dermatitis caused by drugs, lichen planus, pityriasis rubra pilaris, vitiligo, prurigo nodularis, dermatitis caused by drugs, and the like for the first time. The traditional Chinese medicine composition can be used for treating skin diseases, systemic sclerosis, hidradenitis suppurativa, granulomatous skin diseases, vitiligo, dermatomyositis, chronic skin itch and alopecia areata, and has the technical progress of obviously improving skin erythema, papule, edema, scale, moss and ulceration symptoms.
Owner:SUZHOU UNIV

Application of centella glycosyl transferase gene in catalyzing glycosylation of asiatic acid and madecassic acid

The invention belongs to the technical field of plant genetic engineering, and particularly relates to application of a centella asiatica glycosyl transferase gene in catalyzing glycosylation of asiatic acid and madecassic acid. The nucleotide sequence of the gene is shown as SEQ ID No.1, and the protein coded by the gene can catalyze the C-28 site of asiatic acid and madecassic acid to perform glucose group modification so as to generate asiatic acid monoglucoside and madecassic acid monoglucoside, and preferentially catalyzes madecassic acid. By constructing a metabolic regulation network, the genes are widely and accurately screened, and the glycosylation process of catalyzing asiatic acid and madecassic acid is analyzed; an important reference basis is provided for improving the glycosylation efficiency of asiatic acid and madecassic acid and the yield of asiaticoside and madecassoside in the in-vitro synthesis and industrial production process of the centella asiatica triterpenoid saponin, and an important theoretical support is provided for large-scale production of the centella asiatica active saponin.
Owner:HAINAN UNIVERSITY SANYA NANFAN RESEARCH INSTITUTE

Moisturizing anti-aging nanoemulsion, preparation method thereof and moisturizing essence

The invention relates to the technical field of cosmetics, in particular to moisturizing and anti-aging nanoemulsion, a preparation method thereof and moisturizing essence. The moisturizing and anti-aging nanoemulsion comprises the following raw materials in percentage by mass: 90-99% of an anti-aging component and 1-10% of a moisturizing component, and the anti-aging component comprises the following raw materials in percentage by mass: 1-20% of a glycosylglycerol solution, 0.5-3% of nicotinamide adenine dinucleotide, 0.1-5% of sodium coramate and the balance of a solvent; the moisturizing component comprises ceramide lipidosome. The raw materials in the moisturizing and anti-aging nanoemulsion synergistically exert effects, the moisturizing and anti-aging effects of the moisturizing and anti-aging nanoemulsion are improved, meanwhile, the stability and applicability of the moisturizing and anti-aging nanoemulsion are enhanced, and the moisturizing and anti-aging nanoemulsion is mild and non-irritant to skin and safe to use. The preparation method of the moisturizing anti-aging nanoemulsion is simple in process, high in production efficiency and beneficial to industrial production. The moisturizing essence has more remarkable moisturizing and anti-aging effects by adding the moisturizing and anti-aging nanoemulsion, and is safe to use.
Owner:GUANGDONG HANDSOME BIOLOGICAL TECH CO LTD

Prebiotic dried sweet potatoes and making technology thereof

The invention belongs to the technical field of functional food, and relates to prebiotic dried sweet potatoes and a preparation method thereof. Comprising the following steps: thermally drying the surfaces of cut sweet potato strips / slices, atomizing and spraying alpha-amylase, and then steaming and liquefying; the steaming and liquefying process comprises the following steps: steaming at 55-65 DEG C, and heating to 85-100 DEG C for steaming; performing primary drying, atomizing and spraying an enzyme preparation solution on the surfaces of the primarily dried sweet potato strips / slices, and performing saccharification and glucoside conversion; enzyme preparations in the enzyme preparation solution are beta-amylase and alpha-glucosidase; and carrying out two-stage drying dehydration on the saccharified and glucoside-converted dried sweet potatoes, cooling, and carrying out high-temperature sterilization. The preparation method provided by the invention is simple and convenient in process; rich starch and soluble sugar of the sweet potatoes are converted into bifidus factor isomaltooligosacharide, so that the product has a probiotic function, and the functionality and additional value of the product are increased; and the prepared dried sweet potatoes also have a preservative effect.
Owner:SHANDONG FOOD & FERMENT IND RES & DESIGN INST

Skin-tightening anti-wrinkle essence and preparation method thereof

PendingCN120284764ACosmetic preparationsToilet preparationsPara-hydroxyacetophenoneMicrosphere
The invention belongs to the technical field of cosmetics, and discloses skin-tightening and anti-wrinkle essence. The skin-tightening anti-wrinkle essence is prepared from the following raw materials in percentage by mass: 1.5 to 2.5 percent of acetyl hexapeptide-8, 2.0 to 3.0 percent of palmitoyl pentapeptide-4, 3.0 percent of hydroxypropyl tetrahydropyrantriol, 2.0 percent of lipidosome-coated vitamin C ethyl ether, 0.5 percent of resveratrol PLGA microspheres, 0.8 percent of ceramide NP, 1.2 percent of pachymaran, 5.0 percent of glyceryl polyether-26, 0.3 percent of sodium hyaluronate, 0.5 percent of p-hydroxyacetophenone and 1, 3-propanediol, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate and the balance of water. The 1, 2-hexanediol accounts for 0.6%, and the balance is deionized water. Multi-target anti-wrinkle, deep moisturizing and long-acting repairing are achieved by scientifically compounding active ingredients such as acetyl hexapeptide-8 and palmitoyl pentapeptide-4 and combining a lipidosome wrapping technology and a nano-microsphere slow release technology, the preparation process comprises the steps of lipidosome homogenization, nano-microsphere multiple emulsion method and low-temperature emulsification, the ingredient stability and transdermal efficiency are ensured, and the skin care effect is good. Experiments prove that the essence can significantly improve skin elasticity and reduce wrinkles, and has a significant anti-aging effect.
Owner:BEIJING YUANYANG BIOTECHNOLOGY CO LTD

Method for optimizing fertilization amount of astragalus mongolicus

PendingCN119655037Aimprove qualityOptimize the amount of fertilizer appliedFertilising methodsRoot crop cultivationCalycosinPhosphorus fertilizer
The invention discloses a method for optimizing the fertilization amount of astragalus mongolicus. The method comprises the following steps: dividing land parcels, applying base fertilizer, transplanting astragalus membranaceus, applying nitrogen fertilizer, phosphate fertilizer and potash fertilizer in different dosages to astragalus membranaceus in each land parcel, sampling in the growing period, and measuring astragalus membranaceus root length, root diameter, underground part dry weight, astragaloside content and calycosin-7-glucoside as astragalus membranaceus quality indexes. According to the method, the total yield of astragalus mongholicus is measured in the harvesting period to serve as the yield index of astragalus mongholicus, a comprehensive membership function method is combined with a fertilizer effect equation to optimize the fertilization proportion, and the obtained optimal fertilization formula is that the fertilization amount proportion of N: P: K is 1: 1.5: 2.2, and the element proportion of N: P: K is 5: 2: 12. The yield and quality of astragalus membranaceus can be improved, and popularization significance is achieved.
Owner:NORTHWEST A & F UNIV +2

Oxidized resveratrol-containing multi-dimensional anti-pollution composition suitable for sensitive skin and application of oxidized resveratrol-containing multi-dimensional anti-pollution composition

The invention relates to the technical field of cosmetics, and particularly discloses an oxyresveratrol-containing multi-vitamin anti-pollution composition suitable for sensitive skin and application of the oxyresveratrol-containing multi-vitamin anti-pollution composition, the multi-vitamin anti-pollution composition comprises oxyresveratrol, epigallocatechin gallic acid glucoside, acetylchitosamine and annona squamosa extract; the mass ratio of the oxyresveratrol to the epigallocatechin gallic acid glucoside to the acetylchitosamine to the annona squamosa extract is (0.1 to 3) to (0.001 to 0.1) to (1 to 10) to (0.1 to 5). The anti-pollution composition provided by the invention achieves the effects of relieving, repairing and whitening by simultaneously resisting various pollutants such as air pollution, ultraviolet rays, heavy metals and the like, and comprehensively solves the problems of yellow smell and sensitivity of skin.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Application of pinoresin-4-O-glucoside in preparation of medicine for treating allergic asthma disease

PendingCN119258083AImprove pathological changesInhibit the increase of inflammatory factorsOrganic active ingredientsRespiratory disorderAnti-asthmatic drugDisease
The invention discloses an application of pinoresin-4-O-glucoside in preparation of a medicine for treating allergic asthma diseases, and according to the application provided by the invention, the pinoresin-4-O-glucoside can inhibit expression and activity of induced nitric oxide synthase, remarkably improve airway hyperresponsiveness, relieve lung inflammation and relieve expression of asthma related indexes, and can be used for treating allergic asthma diseases. The application has a prospect of developing a novel anti-asthma medicine.
Owner:THE THIRD PEOPLES HOSPITAL OF CHENGDU

Mitochondrial energy improving composition based on plant stem cells, application and cosmetics

The invention belongs to the field of daily chemicals, and discloses a mitochondrial energy improving composition based on plant stem cells, application and cosmetics, the composition comprises the following components by weight: 0.0005-1 part of sunflower bud extract; 0.0005 to 1 part of a melissa officinalis extract; and 0.0005 to 1 part of epigallocatechin gallo glucoside or epigallocatechin gallate. According to the composition disclosed by the invention, the sunflower bud extract, the melissa officinalis extract, the epigallocatechin gallyl glucoside or the epigallocatechin gallate are combined, and the combination of the sunflower bud extract, the melissa officinalis extract, the epigallocatechin gallyl glucoside and the epigallocatechin gallate has the effects of obviously improving the cell mitochondrial dysfunction, improving the mitochondrial energy and increasing the content of I-type collagen; the composition can be used as a potential optional scheme of anti-wrinkle active ingredients in cosmetics.
Owner:HUAANTANG BIOTECH GRP CO LTD

Environment-friendly cover plate glass cleaning agent and preparation method thereof

The invention relates to the technical field of glass cleaning agents, in particular to an environment-friendly cover plate glass cleaning agent and a preparation method thereof. The environment-friendly cover plate glass cleaning agent comprises the following raw materials in percentage by weight: 12-20% of inorganic base, 8-12% of a surfactant, 5-8% of a chelating agent, 3-5% of a humectant, 1-3% of an adsorbent, 1-3% of a dispersing agent, 0.3-1% of a buffering agent and the balance of deionized water, the surfactant is dodecyl glucoside and dodecyl ethyoxyl sulphobetaine, and the weight range ratio of the dodecyl glucoside to the dodecyl ethyoxyl sulphobetaine is (3-1): 1; the chelating agent is one or more of sodium gluconate, sodium polyaspartate and sodium polyepoxysuccinate. According to the present invention, the degradable surfactant and the degradable chelating agent are adopted, and the dispersant is added to modify the nanometer titanium dioxide, such that the low pollution property is achieved while the high decontamination efficiency and the anti-fingerprint ability are considered.
Owner:DONGGUAN JINGBO PHOTOELECTRIC BIT CO

Method for biosynthesizing epigallocatechin gallate glucoside

The invention discloses a method for biosynthesizing epigallocatechin gallate glucoside, and belongs to the technical field of biocatalytic synthesis. According to the method, a sucrose phosphorylase mutant is adopted as a catalyst, the sucrose phosphorylase mutant is subjected to single-point mutation or combined mutation on the basis of an amino acid sequence SEQ ID NO.1, and the enzyme activity of the sucrose phosphorylase is improved through mutation; the mutant is utilized to realize efficient catalytic synthesis of epigallocatechin gallate glucoside, and in the whole catalytic process, the synthesis method is mild in condition, simple to operate, short in reaction time and high in catalytic efficiency, and has a good application prospect.
Owner:NANJING TECH UNIV

Pressure-resistant and anti-permeation deep-sea intrinsic antifouling polyurethane as well as preparation method and application of pressure-resistant and anti-permeation deep-sea intrinsic antifouling polyurethane

The invention discloses a pressure-resistant and anti-permeation deep sea intrinsic antifouling poly-fatty ammonia glycol as well as a preparation method and application of the pressure-resistant and anti-permeation deep sea intrinsic antifouling poly-fatty ammonia glycol. The deep-sea intrinsic antifouling poly-fatty amino vinegar comprises polymer soft segments, antibacterial hard segments and polyiso-oxoacid chain segments, wherein the polymer soft segments, the antibacterial hard segments and the polyiso-oxoacid chain segments are alternately distributed; wherein the antibacterial hard segment comprises a barking group two-fat unit. The antibacterial hard segment in the deep-sea intrinsic antifouling poly-fatty ammonia endows the poly-fatty ammonia glucoside with a fouling organism contact killing function, and the barking ring and the poly-fatty ammonia glucoside synergistically endow the deep-sea intrinsic antifouling poly-fatty ammonia glucoside with high pressure resistance and high permeability; meanwhile, the deep-sea intrinsic antifouling poly-fatty ammonia glucoside is suitable for surface antifouling of thousand-deep-sea environment equipment, can resist deep washing high pressure and seawater permeation, and can effectively prevent adhesion of deep washing bacteria and fouling organisms.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI

Preparation method for enhancing inhibitory activity of lonicera caerulea juice xanthine oxidase through fermentation of plant lactobacillus

According to the preparation method disclosed by the invention, the whole fruit juice of the lonicera caerulea (which retains fruit residues) is fermented by virtue of the plant lactobacillus KLDS1.0391, KLDS1.0320 or KLDS1.0368, so that the xanthine oxidase (XO) inhibition activity is remarkably improved. After fermentation, the XO inhibition rate is increased to 48-50.87% (the content of unfermented juice is 31.21%), the total phenol content is increased by 15-24.3%, and the contents of main XO inhibitors in the lonicera caerulea: cyanidin-3-O-glucoside (IC50 = 115.28 [mu] M), cyanidin-3, 5-diglucoside (IC50 = 116.34 [mu] M), peonidin-3-glucoside (IC50 = 105.34 [mu] M), quercetin (IC50 = 88.75 [mu] M), catechin (IC50 = 110 [mu] M) and caffeoylquinic acid (IC50 = 250.35 [mu] M) are remarkably increased. Wherein the quercetin content is increased by 73.8% at most (KLDS1.0320 strain fermentation is performed for 24 hours), and the XO inhibition rate is increased from 31.21% to 50.87%. Technical support is provided for development of a natural XO inhibitor and a functional fermented beverage, so that a new thought is provided for functional fermented juice with lonicera caerulea as a key component.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Traditional chinese medicine composition and use thereof

The disclosure relates to a traditional Chinese medicine composition, comprising active ingredients derived from Cornu caprae or Cornu saigae tataricae, Radix scutellariae, Bulbus fritillariae ussuriensis, Radix glycyrrhizae, Radix et rhizoma rhei, Gypsum fibrosum, Calculus bovis artifactus and Lapis Chloriti, the said active ingredients comprise in parts by weight: at least 1600 parts of amino acids; at least 120 parts of gallic acid; at least 130 parts of liquiritin; at least 20 parts of liquiritigenin; at least 400 parts of baicalin; at least 40 parts of oroxyloside; at least 120 parts of wogonoside; at least 280 parts of glycyrrhizic acid; at least 12 parts of chrysin-7-O-β-D-glucoronic acid; at least 50 parts of aloe-emodin-8-O-β-D-glucopyranoside; at least 30 parts of chrysophanol-1-O-β-D-glucopyranoside; at least 45 parts of chrysophanol-8-O-β-D-glucopyranoside; at least 260 parts of hyodeoxycholic acid; at least 150 parts of cholic acid. The traditional Chinese medicine composition in the present invention possess antipyretic, anti-inflammatory and antitussive effects.
Owner:JIANGSU KANION PHARMA CO LTD

Screening, verification and detection method for allergen substances in carthamin yellow injection

PendingCN119936224AOrganic active ingredientsComponent separationCarthamus yellowRutin
The invention discloses a screening method of allergen substances in a carthamin yellow injection, a verification method of the allergen substances in the carthamin yellow injection, a detection method of the allergen substances in the carthamin yellow injection and a production process of the carthamin yellow injection. The screening method of the allergen substances in the carthamin yellow injection comprises the following steps: S1, extracting components in the carthamin yellow injection; s2, separating and screening components in the extract by adopting a high performance liquid chromatography-ultraviolet detection-mass spectrum and human serum albumin combined detection technology; and S3, screening out a substance which can be combined with the HSA, and determining the substance as a sensitization hapten substance which has sensitization potential. The invention aims to detect that the 6-hydroxykaempferol-3-rutin-6-glucoside has HAS binding characteristic, hapten attribute and sensitization potential, and can provide basis for process improvement of carthamin yellow injection and reduce the sensitization risk in clinical application.
Owner:CHINA INST FOR RADIATION PROTECTION

Sunscreen composition as well as preparation method and application thereof

The invention relates to a sunscreen composition as well as a preparation method and application thereof. The sunscreen composition comprises a coco-glucoside-coconut oil alcohol compound, polyethylene glycol stearate, dextrin palmitate, butyl octanol salicylate and titanium dioxide. The dextrin palmitate, the butyl octanol salicylate and the coco-glucoside-coconut oil alcohol compound in the composition are matched with one another, so that the composition has excellent wetting, dispersing and suspending effects on the titanium dioxide powder, the sunscreen performance of the composition is greatly improved, and the composition has a synergistic effect in the aspects of improving the stability of the composition and improving the sunscreen effect. Meanwhile, the coco-glucoside-coconut oil alcohol compound can be compatible with polyethylene glycol stearate, so that a sunscreen product further prepared from the composition does not need to be removed by a cleaning product, and the sunscreen product can be washed with clear water.
Owner:GUANGZHOU HAIGUI PAPA BIOTECHNOLOGY CO LTD

Herbal amino acid face cleaning mousse

According to the herbal amino acid face cleaning mousse disclosed by the invention, performance comparison is carried out on high and low addition amounts of various surfactants, a data basis is provided for compounded surfactants, and then a face cleaning mousse system is constructed by utilizing a compounded optimal surfactant group; the cleansing mousse is good in stability, rich and fine in foam, good in washing smoothness, easy to wash cleanly and low in water loss rate, skin dryness after use is reduced, and diversified requirements of consumers are met. By optimizing the dosage of glycerol and 1, 3-butanediol, the foam texture is better, and the foam is more elastic. By adding the jojoba oil, the irritation to the skin and eyes is minimized while the facial greasy dirt is mildly washed off, and obvious moistening and moisturizing effects are brought. By adding raspberry ketone and raspberry ketone glucoside, a preservative-free system is constructed, and the anti-oxidation effect is achieved; by means of the herbal extracts, product irritation is reduced, damage of free radicals is prevented, the resistance of skin is improved, and the product can be applied to various skin types better.
Owner:NANJING COLLEGE OF CHEM TECH

Whitening and freckle-removing essence water and production process thereof

The invention discloses a whitening and freckle-removing essence which comprises the following components: a calendula extract, pure water, 1, 2-pentanediol, methylpropanediol, carbomer, arginine, nicotinamide, a freckle-removing essence, a natural plant penetration enhancer, hydroxyethyl piperazine ethanesulfonic acid, small-molecule ellagic acid, dipropylene glycol, 1, 2-propylene glycol, ethanol and water. The composition is prepared from 1, 2-hexanediol, caprylyl glycol, ethylhexylglycerin, raspberry ketone glucoside and a PEG / PPG-17 / 6 copolymer. The invention further discloses a production process of the whitening and freckle-removing essence water. The invention has the following advantages: with pure natural plants as a main product, the skin has obvious change after being used for a week, specifically, pregnancy spots, sunburn, chloasma, pigmentation after inflammation and other color spots on the face can be reduced and faded, the face skin can be whitened, the face is mild and non-irritating, and the effects of improving uneven skin color, brightening skin color and the like can be achieved.
Owner:FEILANG BIOTECHNOLOGY (HUBEI) CO LTD

Leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite

The invention relates to the technical field of aquaculture, in particular to a leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite. The Leiocassis longirostris intestinal health functional additive comprises the following functional components: chondroitin sulfate, N-acetyl-D-galactosamine, 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4'- The composition is prepared from the following raw materials: 4, 6-dihydroxyflavone, polydatin, ascorbic acid, glucoside, arabinogalactan, 3-O-beta-D-galactopyranosyl-L-arabinose, tyramine, 4A-hydroxytetrahydrobiopterin, hyaluronic acid and 3-mercapto-2-butanol. According to the technical scheme, the technical problem that an existing probiotic viable bacterium preparation is difficult to meet the intestinal health management requirement in intensive culture of the leiocassis longirostris can be solved. Compared with the prior art, the scheme is more efficient, stable and safe, healthy development of the Leiocassis longirostris breeding industry can be effectively promoted, and the method has ideal application and popularization prospects.
Owner:FISHERIES INST SICHUAN ACADEMY OF AGRI SCI

Preparation method of fusidic acid cream

The invention provides a preparation method of fusidic acid emulsifiable paste, and relates to the field of pharmaceutical preparations, and the preparation method comprises the following steps: step 1, preparation of fusidic acid nanoparticles, step 2, preparation of an oil phase of the emulsifiable paste, step 3, preparation of a water phase of the emulsifiable paste, step 4, emulsification, and step 5, mixing. According to the fusidic acid nanoparticles, firstly, a composite carrier is prepared, then fusidic acid, PLGA, the composite carrier and absolute ethyl alcohol are mixed, a nanoparticle oil phase is obtained, then PVA, PVP, sodium dodecyl glucoside sulfonate and dipotassium ethylenediaminetetraacetate are mixed with deionized water, a nanoparticle water phase is obtained, and finally a nanoparticle suspension is obtained through mixing. The fusidic acid emulsifiable paste prepared by the method can effectively solve the problems that the traditional emulsifiable paste bulk drugs are easy to agglomerate, the drug molecule particle size is large and the like, and the transdermal absorption rate and bioavailability of fusidic acid are improved, so that the antibacterial effect is enhanced.
Owner:CHONGQING CONQUER PHARML