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630 results about "Glucoside" patented technology

A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes.

Anti-wrinkle and anti-aging composition as well as preparation method and application thereof

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.
Owner:GUANGZHOU SUNLIFE BIOTECHNOLOGY CO LTD

Moisturizing anti-aging nanoemulsion, preparation method thereof and moisturizing essence

The invention relates to the technical field of cosmetics, in particular to moisturizing and anti-aging nanoemulsion, a preparation method thereof and moisturizing essence. The moisturizing and anti-aging nanoemulsion comprises the following raw materials in percentage by mass: 90-99% of an anti-aging component and 1-10% of a moisturizing component, and the anti-aging component comprises the following raw materials in percentage by mass: 1-20% of a glycosylglycerol solution, 0.5-3% of nicotinamide adenine dinucleotide, 0.1-5% of sodium coramate and the balance of a solvent; the moisturizing component comprises ceramide lipidosome. The raw materials in the moisturizing and anti-aging nanoemulsion synergistically exert effects, the moisturizing and anti-aging effects of the moisturizing and anti-aging nanoemulsion are improved, meanwhile, the stability and applicability of the moisturizing and anti-aging nanoemulsion are enhanced, and the moisturizing and anti-aging nanoemulsion is mild and non-irritant to skin and safe to use. The preparation method of the moisturizing anti-aging nanoemulsion is simple in process, high in production efficiency and beneficial to industrial production. The moisturizing essence has more remarkable moisturizing and anti-aging effects by adding the moisturizing and anti-aging nanoemulsion, and is safe to use.
Owner:GUANGDONG HANDSOME BIOLOGICAL TECH CO LTD

Environment-friendly cover plate glass cleaning agent and preparation method thereof

The invention relates to the technical field of glass cleaning agents, in particular to an environment-friendly cover plate glass cleaning agent and a preparation method thereof. The environment-friendly cover plate glass cleaning agent comprises the following raw materials in percentage by weight: 12-20% of inorganic base, 8-12% of a surfactant, 5-8% of a chelating agent, 3-5% of a humectant, 1-3% of an adsorbent, 1-3% of a dispersing agent, 0.3-1% of a buffering agent and the balance of deionized water, the surfactant is dodecyl glucoside and dodecyl ethyoxyl sulphobetaine, and the weight range ratio of the dodecyl glucoside to the dodecyl ethyoxyl sulphobetaine is (3-1): 1; the chelating agent is one or more of sodium gluconate, sodium polyaspartate and sodium polyepoxysuccinate. According to the present invention, the degradable surfactant and the degradable chelating agent are adopted, and the dispersant is added to modify the nanometer titanium dioxide, such that the low pollution property is achieved while the high decontamination efficiency and the anti-fingerprint ability are considered.
Owner:DONGGUAN JINGBO PHOTOELECTRIC BIT CO

Method for biosynthesizing epigallocatechin gallate glucoside

PendingCN120536400ABacteriaMicroorganism based processesPtru catalystSucrose phosphorylase
The invention discloses a method for biosynthesizing epigallocatechin gallate glucoside, and belongs to the technical field of biocatalytic synthesis. According to the method, a sucrose phosphorylase mutant is adopted as a catalyst, the sucrose phosphorylase mutant is subjected to single-point mutation or combined mutation on the basis of an amino acid sequence SEQ ID NO.1, and the enzyme activity of the sucrose phosphorylase is improved through mutation; the mutant is utilized to realize efficient catalytic synthesis of epigallocatechin gallate glucoside, and in the whole catalytic process, the synthesis method is mild in condition, simple to operate, short in reaction time and high in catalytic efficiency, and has a good application prospect.
Owner:NANJING TECH UNIV

Preparation method for enhancing inhibitory activity of lonicera caerulea juice xanthine oxidase through fermentation of plant lactobacillus

According to the preparation method disclosed by the invention, the whole fruit juice of the lonicera caerulea (which retains fruit residues) is fermented by virtue of the plant lactobacillus KLDS1.0391, KLDS1.0320 or KLDS1.0368, so that the xanthine oxidase (XO) inhibition activity is remarkably improved. After fermentation, the XO inhibition rate is increased to 48-50.87% (the content of unfermented juice is 31.21%), the total phenol content is increased by 15-24.3%, and the contents of main XO inhibitors in the lonicera caerulea: cyanidin-3-O-glucoside (IC50 = 115.28 [mu] M), cyanidin-3, 5-diglucoside (IC50 = 116.34 [mu] M), peonidin-3-glucoside (IC50 = 105.34 [mu] M), quercetin (IC50 = 88.75 [mu] M), catechin (IC50 = 110 [mu] M) and caffeoylquinic acid (IC50 = 250.35 [mu] M) are remarkably increased. Wherein the quercetin content is increased by 73.8% at most (KLDS1.0320 strain fermentation is performed for 24 hours), and the XO inhibition rate is increased from 31.21% to 50.87%. Technical support is provided for development of a natural XO inhibitor and a functional fermented beverage, so that a new thought is provided for functional fermented juice with lonicera caerulea as a key component.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite

The invention relates to the technical field of aquaculture, in particular to a leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite. The Leiocassis longirostris intestinal health functional additive comprises the following functional components: chondroitin sulfate, N-acetyl-D-galactosamine, 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4'- The composition is prepared from the following raw materials: 4, 6-dihydroxyflavone, polydatin, ascorbic acid, glucoside, arabinogalactan, 3-O-beta-D-galactopyranosyl-L-arabinose, tyramine, 4A-hydroxytetrahydrobiopterin, hyaluronic acid and 3-mercapto-2-butanol. According to the technical scheme, the technical problem that an existing probiotic viable bacterium preparation is difficult to meet the intestinal health management requirement in intensive culture of the leiocassis longirostris can be solved. Compared with the prior art, the scheme is more efficient, stable and safe, healthy development of the Leiocassis longirostris breeding industry can be effectively promoted, and the method has ideal application and popularization prospects.
Owner:FISHERIES INST SICHUAN ACADEMY OF AGRI SCI

Feed additive for synergistically improving oxidative stress resistance of broiler chickens based on oleuropein-luteoloside-maslinic acid ternary combination and application of feed additive

The invention discloses a feed additive for synergistically improving oxidative stress resistance of broiler chickens based on oleuropein-luteoloside-maslinic acid ternary combination and application of the feed additive, the feed additive is the olea europaea leaf extract, the total polyphenol content of the feed additive is about 52%, the total flavone content is 7%, and the total flavone content is 5%. The feed is mainly composed of oleuropein, luteolin-7-beta-glucoside and maslinic acid, the oleuropein, the luteolin-7-beta-glucoside and the maslinic acid are sequentially added in a molar ratio of 6: 1: 1 to generate a synergistic anti-oxidative stress effect, and when the feed is applied to breeding on the basis of corn-soybean daily ration of broilers, the daily gain of the broilers can be obviously increased, the feed conversion ratio is reduced, and the feed conversion rate is increased. The intestinal micro-ecological health, the anti-oxidative stress effect and the organism immunity are improved, and the infection rate and the death rate of intestinal diseases such as diarrhea of broilers are reduced. The product has the advantages of being simple and convenient to prepare and use, free of toxic and side effects, beneficial to broiler chicken growth and human health, free of the problems of drug resistance, drug residues and the like, and capable of promoting chicken meat quality improvement and the like.
Owner:INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY

Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheet, laminate, and glucan derivative

The present invention provides a novel pressure-sensitive adhesive composition including a glucan derivative. The pressure-sensitive adhesive composition of the present invention includes a glucan derivative G having a glucoside bond A, and a glucoside bond B having a different bonding form from the glucoside bond A. The glucoside bond A is, for example, a 1,6-glucoside bond. A pressure-sensitive adhesive sheet 1 of the present invention is formed from the pressure-sensitive adhesive composition. A laminate 10 of the present invention includes the pressure-sensitive adhesive sheet 1 and a substrate sheet 2.
Owner:NITTO DENKO CORP

Acne-removing and recurrence-preventing composition suitable for acne-sensitive skin and its application

The present disclosure provides an acne-removing and recurrence-preventing composition suitable for acne-sensitive skin and its application, belonging to the field of cosmetic technology. The present disclosure selects epigallocatechin gallate glucoside, brazilin, Hibiscus sabdariffa flower extract, Ziziphus jojoba bark extract, linseed oil unsaponifiables, and guaiac extract as active ingredients of the acne-removing and recurrence-preventing composition. The active ingredients interact with each other to quickly inhibit the growth of acne-related pathogens and regulate the skin microecology; effectively inhibit skin inflammation throughout the acne process, play a role in preventing and suppressing inflammation, effectively repair the skin barrier, reduce redness, and regulate the skin's oil balance to prevent acne recurrence; in addition, the acne-removing and recurrence-preventing composition also has the effect of removing yellowness, evens skin tone, and improves skin roughness. The acne-removing and recurrence-preventing composition is mild and non-irritating and can be used on sensitive skin, expanding the application range of the acne-removing and recurrence-preventing composition.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Sulfur tea tree essential oil silicone-oil-free shampoo and preparation method thereof

The invention relates to the field of washing, and particularly discloses sulfur tea tree essential oil silicone oil-free shampoo. The shampoo comprises the following raw materials: water; fatty alcohol polyoxyethylene ether sodium sulfate; coconut oil monoethanolamide; hydroxypropyl guar gum hydroxypropyl trimethyl ammonium chloride; disodium EDTA (Ethylene Diamine Tetraacetic Acid); cocamidopropyl betaine is added; an alkyl glycoside; sodium lauroyl sarcosine; allantoin; pPG-3 (Polypropylene Glycol) octyl ether; a polyquaternary ammonium salt-52; colloidal sulfur; d-panthenol; 10 parts of polyquaternium-10; a pearling agent; maltotetraose; tea tree essential oil; a preservative; a colorant; daily-use essence; and citric acid monohydrate. The preparation method comprises the following steps: sequentially adding the raw materials, dispersing and dissolving, adjusting the pH value, filtering and discharging. The shampoo disclosed by the invention can keep water-oil balance of scalp and reduce the problems of hair damage and dryness at the same time.
Owner:ZHEJIANG DACHENG TECH CO LTD

Multi-site mutant of glucosyltransferase and application thereof

The invention discloses a multi-site mutant of glucosyltransferase and an application of the multi-site mutant. A GT 1 family O-glycosyl transferase UGT73C33 derived from liquorice is mutated, an excellent multi-site mutant of the O-glycosyl transferase is obtained through screening, the multi-site mutant contains three mutation sites, F148 is mutated into W, F388 is mutated into W, and A389 is mutated into T. The novel O-glycosyl transferase mutant C33-F148W-F388W-A389T is high in specificity, the selectivity of the novel O-glycosyl transferase mutant C33-F148W-F388W-A389T for generating luteolin-4 '-O-glucoside through specific conversion of luteolin reaches 80%, the novel O-glycosyl transferase mutant is high in catalytic activity, and the yield of luteolin-4'-O-glucoside reaches 156.8 mg / L under suitable conditions. The invention provides a unique biocatalyst and a conversion process thereof for the preparation of luteolin-4 '-O-glucoside with high activity and high added value.
Owner:NANJING FORESTRY UNIV

Recombinant escherichia coli for producing sucrose phosphorylase as well as construction method and application of recombinant escherichia coli

PendingCN120591229ABacteriaMicroorganism based processesEscherichia coliSucrose phosphorylase
The invention discloses recombinant escherichia coli for producing sucrose phosphorylase as well as a construction method and application of the recombinant escherichia coli, and belongs to the technical field of biological engineering. The sucrose phosphorylase is constructed, the amino acid sequence of the sucrose phosphorylase is shown as SEQ ID NO.11, a recombinant escherichia coli BdSP-L341V / L343F / V346P for expressing the sucrose phosphorylase is constructed, the sucrose phosphorylase expressed by recombinant bacteria or whole cells of the recombinant bacteria are used for carrying out catalytic reaction, and efficient production of ascorbyl glucoside can be realized. The invention also provides a method for producing ascorbic acid glucoside, the catalytic reaction is carried out at normal temperature and normal pressure, toxic and harmful organic solvents are not used, and the pollution to the environment is reduced; the whole catalytic process is a one-step reaction, has the advantages of high conversion rate, simple purification step and simple process, can better save the production cost, and has wide industrial application prospects.
Owner:HEFEI UNIV OF TECH +1

Solid essence composition, solid essence prepared from solid essence composition and application of solid essence composition

The invention relates to the technical field of nicotine oral delivery essence, and discloses a solid essence composition, solid essence prepared from the solid essence composition and application of the solid essence composition. The solid essence composition comprises the following components: a liquid essence base material, a water-soluble embedding medium and ethyl vanillin glucoside. The solid essence prepared from the solid essence composition can be used for preparing nicotine bags. The solid essence prepared from the solid essence composition provided by the invention is high in flavor stability; the prepared solid essence can still maintain the original flavor of the essence to a relatively high degree after being placed at high temperature and high pH for 12 hours; the overall stability of the solid essence is protected by adding ethyl vanillin glucoside and an embedding technology, so that the flavor, color and luster of the nicotine bag are improved.
Owner:DONGGUAN HONGFU BIOTECHNOLOGY CO LTD

Nano-liposome emulsion with moisturizing effect prepared by microjet method and preparation method of nano-liposome emulsion

The invention belongs to the technical field of cosmetics, particularly discloses moisturizing nano-liposome emulsion prepared by a microjet method and a preparation method of the moisturizing nano-liposome emulsion, and aims to solve the problems of poor stability of active ingredients, low transdermal absorption efficiency, single effect and non-uniform particle size in a liposome preparation process in the existing moisturizing cosmetics. The nano-liposome emulsion is prepared from glycosylglycerol, acetylchitosamine, tremella polysaccharide, a myrothamnus flabellifolia leaf / stem extract, an artemisia annua extract, a lactobacillus fermentation product, flat nuclear wood oil, hydrogenated lecithin and phosphatidylcholine. The emulsion has excellent moisturizing, soothing and repairing effects, can be used for preparing skin care products such as water aqua, emulsion and cream, and has the advantages of high utilization rate of active ingredients and good stability.
Owner:HAOYU (GUANGZHOU) COSMETICS MFG CO LTD +1

Shuanghuangbai traditional Chinese medicine preparation for treating myelosuppression and preparation method and detection method of Shuanghuangbai traditional Chinese medicine preparation

The invention discloses a radix astragali, rhizoma polygonati and ligustrum lucidum ait traditional Chinese medicine preparation for treating myelosuppression as well as a preparation method and a detection method thereof. The preparation is prepared from 50-150 parts of radix astragali, 50-150 parts of wine-processed rhizoma polygonati, 25-75 parts of wine-processed ligustrum lucidum ait, 50-150 parts of blanched rhizoma drynariae, 50-150 parts of radix trichosanthis and 25-75 parts of herba epimedii. The optimal extraction process and refining process are screened out based on effective components and pharmacological activity through a large number of tests, and the optimal preparation process of the Shuanghuangliangwhitening oral liquid and other traditional Chinese medicine preparations is obtained through stability investigation and verification. According to the invention, a thin layer chromatography is adopted, the four medicinal materials of astragalus membranaceus, glossy privet fruit, rhizoma drynariae and herba epimedii are respectively subjected to thin layer chromatography research, and methodology research shows that the method is stable and feasible. The invention establishes a content determination method for astragaloside, calycosin-7-glucoside, specnuezhenide and icariin, establishes a quality standard, and has important significance for ensuring the clinical curative effect and safety of astragaloside, calycosin-7-glucoside, specnuezhenide and icariin.
Owner:CHANGSHU LEI YUN SHANG PHARM CO LTD

Multi-effect mild facial cleanser and preparation method thereof

The invention discloses a multi-effect mild facial cleanser and a preparation method thereof, and belongs to the technical field of nursing products. The facial cleanser is prepared from the following components: EDTA-2Na (Ethylene Diamine Tetraacetic Acid), an amino acid surfactant, a glucoside surfactant, a betaine surfactant, glycolipid, glycerol, EGDS (Ethylene Diamine Tetraacetic Acid), propylene glycol laurate, water and the like. Based on the matching use of sodium lauroyl methyl aminopropionate, palmitoyl glycine and other amino acid surfactants, the facial cleanser can effectively overcome the technical problems of difficult thickening, poor foam stability and the like of a traditional amino acid facial cleansing product, and also can relieve chronic skin inflammation, restore skin balance and promote microangiogenesis, so that the facial cleanser has the effects of nourishing skin and improving skin quality. The skin is recovered to a young and compact state, and the full components are ensured to have a biodegradable characteristic.
Owner:CHANGSHA PUJI BIOTECH

Method for determining fingerprint spectrum and multi-component content of calamus-far nerve calming mixture

The invention provides a fingerprint spectrum and multi-component content determination method of a calamus-far nerve calming mixture, and relates to the field of quality control of traditional Chinese medicines. 31 common peaks are calibrated by establishing a fingerprint spectrum, and 24 common peaks can clearly belong to polygala tenuifolia. Meanwhile, synchronous content determination of seven components including chlorogenic acid, caffeic acid, ferulic acid, liquiritin, 2, 3, 5, 4 '-tetrahydroxy stilbene-2-O-beta-D-glucoside, 3, 6'-dimustard acyl sucrose and rosmarinic acid is realized. The method is good in precision, high in repeatability and stable and reliable in result, the medicine quality can be comprehensively and accurately reflected and controlled, and powerful support is provided for guaranteeing the safety and effectiveness of the calamus-far Ningmind mixture.
Owner:KUNSHAN TRADITIONAL CHINESE MEDICINE HOSPITAL

A water-oil compartment anti-wrinkle facial mask liquid and its preparation method and facial mask

The present invention discloses a water-oil compartment anti-wrinkle facial mask liquid, a preparation method thereof, and a facial mask. The water-oil compartment anti-wrinkle facial mask liquid includes a water compartment and an oil compartment in the following mass percentages: the water compartment is as follows: water 74.94-88.09%, a thickener 0.1-0.3%, a moisturizer 7-16%, an antibacterial agent 0.4-1%, a neutralizer 0.1-0.3%, a glabra elm bark extract 1.5-2.5%, a balkan moss leaf extract 0.1-0.5%, and epigallocatechin gallate glucoside 0.03-0.08%; the oil compartment is as follows: hydroxydecyl ubiquinone 0.03-0.08%, arabica coffee seed oil 0.05-0.3%, an emollient 3-5%, and a fragrance 0.01-0.05%. The facial mask liquid provided by this application can not only quickly solve the problem of skin anti-wrinkle, but also solve the problem of poor stability after the anti-wrinkle active substances are mixed.
Owner:GUANGZHOU REFEN COSMETICS CO LTD

High-temperature and neutral alkyl glycoside sulfonate as well as preparation method and application thereof

The invention belongs to the technical field of daily chemicals, and particularly relates to high-temperature and neutral alkyl glycoside sulfonate as well as a preparation method and application thereof. The alkyl glucoside sulfonate provided by the invention is obtained by utilizing hydroxyl activity on a glucoside sugar unit to perform chemical modification, and specifically, 1, 3-dichloro-2-propanol is firstly adopted to perform intramolecular crosslinking on alkyl glucoside, and then 3-chloro-2-hydroxy sodium propanesulfonate is adopted to perform anionic modification. The prepared alkyl glycoside sulfonate has the advantages of being mild, low in irritation, high in hard water resistance, good in foaming performance, low in permeation amount on skin and small in residual amount, and can effectively overcome the defects that alkyl glucoside is high in permeability, high in deproteinization and degreasing capacity, large in damage to skin barriers, weak in thickening effect and the like in personal cleaning products; the method is very suitable for being widely used and popularized in daily chemicals.
Owner:GUANGZHOU ZENGCHENG CHAOHUI BIOTECHNOLOGY CO LTD

Dishwashing liquid capable of removing oil stains and pesticide residues and preparation method of dishwashing liquid

The invention relates to a detergent capable of removing oil stains and pesticide residues and a preparation method of the detergent, and belongs to the technical field of daily chemical products. The detergent disclosed by the invention is prepared from the following raw materials in parts by weight: 0.4 to 1.7 parts of chelating agent, 250 to 450 parts of water, 70 to 150 parts of sodium alcohol ether sulphate, 20 to 60 parts of dodecyl glucoside, 10 to 40 parts of cocamidopropyl betaine, 10 to 55 parts of nonionic surfactant, 0.2 to 3.5 parts of plant essential oil, 0.2 to 5 parts of glycerol and 1 to 10 parts of sodium chloride. According to the present invention, the good oil stain removing and pesticide residue removing effects are achieved while the less components are utilized; due to the fact that the components are few, the residual risk of the detergent is lower, the risk of harms to human bodies is lower, and pollution to the environment is smaller; the invention provides a better choice for people who increasingly pursue safety and environmental protection, and better caters to the market demand and the national policy of environmental protection.
Owner:GUANGZHOU HARTONG TECHNOLOGY CO LTD +1

Use of oleanolic acid-28-O-beta-D-glucopyranoside in preparation of anti-colitis drug

A use of oleanolic acid-28-O-β-D-glucopyranoside in the preparation of an anti-colitis drug is provided. The oleanolic acid-28-O-β-D-glucopyranoside has significant anti-ulcerative-colitis activity compared with parent nucleus oleanolic acid and other analogues, and has equivalent efficacy compared with Mesalazine, a first-line drug for the clinical treatment of inflammatory bowel disease, and can also avoid salicylic acid anaphylaxis possibly caused by Mesalazine western medicine treatment, thereby achieving a good application prospect.
Owner:JILIN UNIVERSITY

Construction method and application of specific chromatogram of Shanhaidan pharmaceutical preparation

The invention discloses a construction method and application of a specific chromatogram of a Shanhaidan pharmaceutical preparation, and belongs to the technical field of traditional Chinese medicine detection. The method comprises the following steps: preparing a test solution by using a plurality of different batches of Shanhaidan medicinal preparations in combination with high performance liquid chromatography and mass spectrometry technologies; the preparation method comprises the following steps: preparing a single reference substance solution from uridine, tanshinol, daidzin, p-hydroxybenzoic acid, puerarin, caffeic acid, 3 '-hydroxy puerarin, physcion, calycosin-7-O-beta-D-glucoside, stilbene glucoside, rosmarinic acid, alkannic acid, formononin, salvianolic acid B, daidzein and calycosin-7-one; and respectively carrying out high performance liquid chromatography analysis on the test solution and the reference solution to obtain the characteristic chromatogram of the Shanhaidan pharmaceutical preparation. The method is simple and convenient to operate, high in precision, good in reproducibility and accurate and reliable in result. And at least 16 components can be identified at one time under the same chromatographic condition, so that the detection efficiency is remarkably improved, the time and the cost are saved, and the quality of the Shanhaidan pharmaceutical preparation is comprehensively and scientifically evaluated.
Owner:SHAANXI UNIV OF SCI & TECH

Ploretin-O-monoglucoside glycosyltransferase protein DoUGT019 in dendrobium officinale as well as coding gene and application thereof

The invention relates to the technical field of biology, in particular to a phloretin-O-monoglucoside glycosyl transferase protein DoUGT019 in dendrobium officinale as well as an encoding gene and application thereof, and discloses a phloretin-O-monoglucoside glycosyl transferase protein with an amino acid sequence as shown in SEQ ID NO: 1, which can be used for preparing a glycosyl transferase protein with an amino acid sequence as shown in SEQ ID NO: 1 in the presence of a UDP-glucose donor. The method has the advantages that the method is simple and convenient to operate and can catalyze O-glycosylation of phloretin A ring 2 '-OH, 4'-OH and B ring 4-OH, three high-value monoglucosides, namely phlorizin, trilobatin and phloretin-4-O-glucoside, are synchronously generated, multi-product synthesis can be realized without synergy of various enzymes, the process is greatly simplified, and the use cost of enzyme preparations is reduced. Meanwhile, discovery of the protein reveals a unique phloretin glycosylation metabolic pathway of dendrobium plants, and a cloning and functional verification system of the protein can also be used as a general technical template for research of similar glycosyltransferase to promote technical iteration and theoretical development in the field of glycosylation biosynthesis.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES

Anti-allergy acne-removing composition as well as preparation method and application thereof

The invention relates to an allergy-relieving acne-removing composition and a preparation method and application thereof, and the allergy-relieving acne-removing composition comprises the following raw materials in parts by mass: 1-10 parts of VB-IP, 5-20 parts of hydroxyethyl urea, 1-5 parts of coated salicylic acid, 2-10 parts of wild soybean, 1-5 parts of clerodendranthus spicatus, 1-5 parts of rosewood seeds, 1-10 parts of lactobionic acid, 1-10 parts of gluconolactone, 1-10 parts of mandelic acid, 1-10 parts of glycollic acid, 1-5 parts of octyl dodecyl glucoside and 1-5 parts of cetearyl glucoside. 0.5 to 2 parts of phenoxyethanol and 5 to 30 parts of deionized water; the composition comprises the following components: a wild soybean fermentation extract, a clerodendranthus spicatus fermentation extract and a rosewood seed fermentation extract. Compared with the prior art, the formula is stable, penetration can be promoted, cutin renewal can be accelerated, a sebum film can be repaired, sebum can be adjusted, and the acne removing and skin care effects are good.
Owner:宁波伯通伟达生物医药有限公司

A method for chemical synthesis of hydroxytyrosol glucoside

The application discloses a chemical synthesis method of hydroxytyrosol glucoside. The method uses hydroxytyrosol as a starting material, and acetyl protection, glycosylation, hydrolysis and other steps are performed to prepare the hydroxytyrosol glucoside. The synthesis method of the hydroxytyrosol glucoside has the characteristics of low cost, simple process and industrialization.
Owner:刘小红

A flavonoid glycoside of golden chrysanthemum and its application in preparing medicine for treating hyperlipidemia and fatty liver

The present invention discloses a golden chrysanthemum flavonoid glycoside derived from golden chrysanthemum, wherein the golden chrysanthemum flavonoid glycoside is apigenin 7-O-(6"-O-malonyl)-β-D-glucoside derived from golden chrysanthemum. The present invention separates and purifies apigenin 7-O-(6"-O-malonyl)-β-D-glucoside from golden chrysanthemum for the first time, completes the first synthesis through a 5-step synthesis process with a total yield of 2.7%, and discovers for the first time that the compound has activity in improving hyperlipidemia and fatty liver in vitro and in vivo. Therefore, the compound can be used in the preparation of products for treating related diseases such as hyperlipidemia and fatty liver.
Owner:JIANGSU YIAN FLOWER CO LTD

Application of linariin-6-O-glucoside in preparation of product for preventing and treating osteoporosis

The invention provides application of linariin-6-O-glucoside in preparation of a product for preventing and treating osteoporosis, and relates to the field of biological medicine. According to the invention, dyeing experiments of alkaline phosphatase, alizarin red and tartaric acid resistant acid phosphatase prove that the sesaminin-6-O-glucoside has affinity for FPPS receptors, has the capability of promoting bone marrow mesenchymal stem cells to form bone cells, is superior to that of bisphosphate, and can inhibit the generation of osteoclasts; microCT (micro computed tomography) detection results show that the sesaminin-6-O-glucoside has the effect of relieving the osteoporosis and can promote the formation of bone trabecula. According to the application disclosed by the invention, it is proved for the first time that the sesaminin-6-O-glucoside has the effect of resisting osteoclast formation, and meanwhile, the sesaminin-6-O-glucoside also has a better osteogenesis effect, so that a basis is provided for developing the sesaminin-6-O-glucoside as a potential medicine for treating osteoporosis.
Owner:SICHUAN UNIV

Surfactant and cleaning compositions

PendingUS20260185013A1GlycosideActive agent
Surfactant and cleaning compositions for cleaning of food and beverage processing equipment and milking systems. The surfactant composition includes a hydrocarbon surfactant selected from alkyl glucosides, alkyl poly glucosides and amphoteric-based sultaine surfactants, or combinations thereof, and a fluorosurfactant.
Owner:DELAVAL HLDG AB

Epoxy chloropropane and preparation method thereof

The invention discloses epichlorohydrin and a preparation method thereof. Comprising the following steps: feeding a mixed solution containing chloropropene, hydrogen peroxide and a nonionic surfactant and a titanium silicalite molecular sieve TS-1 catalyst in a fixed bed reactor at a mass space velocity of 0.5-10h <-1 >, and reacting at 20-90 DEG C to obtain the epichlorohydrin. The dosage of the catalyst is 0.1-10 wt% of the chloropropene; the nonionic surfactant is selected from at least one of alkyl glucoside, fatty glyceride, fatty acid sorbitan, polysorbate, polyoxyethylene fatty alcohol ether and nonylphenol polyoxyethylene ether; the molar ratio of the hydrogen peroxide to the nonionic surfactant is (1-50): 1; the molar ratio of chloropropene to hydrogen peroxide is (1-10): 1. The nonionic surfactant is added to promote mixing of the organic phase and the water phase, a large amount of solvent does not need to be added in a traditional process, and a large amount of energy consumption such as solvent evaporation and recovery is avoided; the conversion rate of hydrogen peroxide is greater than 95%, and the selectivity of epoxy chloropropane is 95-99%.
Owner:DALIAN INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

Temperature-resistant oil-displacing discharge aiding agent as well as preparation method and application thereof

The invention relates to the technical field of oilfield chemical engineering, and discloses a temperature-resistant oil-displacing discharge aiding agent, a preparation method and application, dimethylaminoethyl-4-phenyl-2-pyrrolidone and 3-chloro-2-hydroxypropyl glucoside are subjected to a reaction, a product is added into deionized water, and the temperature-resistant oil-displacing discharge aiding agent is prepared. An amphiphilic structure of a hydrophilic quaternary ammonium salt cation group and a hydrophobic benzene ring is introduced into alkyl glycoside, high surface activity is achieved, the surface tension of a prepared cleanup additive aqueous solution is low, the surface tension of flow-back liquid is reduced, flow-back of the liquid is promoted, and the cleanup performance is excellent. And through high-temperature heat treatment, the discharge aiding agent solution still has very low surface tension, and the discharge aiding and flowback performance cannot be influenced.
Owner:PANJIN HUIMING IND