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903 results about "Glucoside" patented technology

A glucoside is a glycoside that is derived from glucose. Glucosides are common in plants, but rare in animals. Glucose is produced when a glucoside is hydrolysed by purely chemical means, or decomposed by fermentation or enzymes.

Plant lactobacillus XD117, application of plant lactobacillus XD117 in fermentation of astragalus membranaceus, astragalus membranaceus fermentation product and preparation method of astragalus membranaceus fermentation product

The invention belongs to the technical field of microbial fermentation, and particularly relates to a plant lactobacillus XD117, application of the plant lactobacillus XD117 in fermentation of astragalus membranaceus, an astragalus membranaceus fermentation product and a preparation method of the astragalus membranaceus fermentation product. The bacterial strain is lactobacillus plantarum XD117 and is preserved in the China Center for Type Culture Collection, and the preservation number of the bacterial strain is CCTCC NO: M 20241730. The preparation method of the astragalus mongholicus fermentation product comprises the following steps: inoculating the lactobacillus plantarum XD117 into astragalus mongholicus enzymatic hydrolysate, and fermenting in a fermentation temperature range suitable for the lactobacillus plantarum XD117 to obtain the astragalus mongholicus fermentation product. The total content of calycosin, formononetin, calycosin glucoside and formononin in the astragalus mongholicus fermentation product is high, and the astragalus mongholicus fermentation product has a very good antioxidant effect.
Owner:江苏菌钥生命科技发展有限公司 +1

Method for improving anti-aging effect of eurotium cristatum tea compound fermentation liquor

The invention provides a technical method for improving the anti-aging effect of eurotium cristatum tea compound fermentation liquor, and belongs to the technical field of microorganisms, the Latin name of eurotium cristatum is Eurotium cristatum, the eurotium cristatum is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC M 2024643. According to the method, the yeast seed solution is inoculated into the tea-sea buckthorn leaf culture solution fermented by the eurotium cristatum, so that the content of anti-aging active components such as procyanidine B2, quercitrin, cyanidin-3-glucoside, nicotinic acid, naringenin and rutin in the fermentation culture solution can be remarkably increased through co-fermentation, and the elastase inhibition rate can be remarkably increased; the anti-aging effect of a component system of the fermentation culture solution is enhanced. The prepared tea-hippophae rhamnoides leaf compound fermentation liquor is suitable for development of anti-aging cosmetics and has a wide market prospect.
Owner:GUANGZHOU ZHONGZHUANG BEAUTY COSMETICS CO LTD +1

Anti-wrinkle and anti-aging composition as well as preparation method and application thereof

The invention belongs to the field of skin care products, and particularly relates to an anti-wrinkle and anti-aging composition as well as a preparation method and application thereof, and the anti-wrinkle and anti-aging composition comprises neurotransmitter inhibition peptide, signal peptide, madecassoside, inositol and glycosylglycerol. The neurotransmitter inhibition type peptide is at least three of acetyl hexapeptide-8, arginine / lysine polypeptide, dipeptide diaminobutyrylbenzylamide diacetate and acetyl octapeptide-3, and the signal type peptide is at least two of palmitoyl pentapeptide-4, decapeptide-4 and acetyl tetrapeptide-9. Compared with the prior art, all the components of the anti-wrinkle and anti-aging composition act on different anti-aging pathways and can be matched with one another from multiple aspects of oxidation resistance, inflammation resistance, moisturizing, cell viability enhancement, wrinkle reduction and the like, a more comprehensive and better anti-aging effect is provided, skin aging is comprehensively resisted, the skin is in a more young state, and the anti-wrinkle and anti-aging composition has the advantages that the anti-wrinkle and anti-aging effects are achieved. And the anti-wrinkle and anti-aging composition is small in irritation and good in stability.
Owner:GUANGZHOU SUNLIFE BIOTECHNOLOGY CO LTD

Tocopherol glucoside and preparation process thereof

The invention belongs to the field of biological fermentation synthetic medicines, and particularly relates to tocopherol glucoside and a preparation process thereof. The synthesis method comprises the following steps: (1) preparing an enzyme catalyst; (2) carrying out enzymatic conversion reaction; (3) purifying ion resin; (4) removing impurities; the synthesis process provided by the invention is simple in route and strong in operability, the prepared tocopherol glucoside is high in purity, the total yield of the product is greater than 30%, and the purity is greater than 95.0%.
Owner:QINGDAO SANRENXING CHEM CO LTD +1

Application of citrus flavonoid glycosyl transferase CitUGT73A78 in biosynthesis of flavonoid glycoside

The invention provides an application of citrus flavonoid glycosyl transferase CitUGT73A78 in biosynthesis of flavonoid glycoside, and belongs to the technical field of gene engineering and enzyme engineering. According to the present invention, the function of the CitUGT73A78 gene is cloned and verified, and the in vitro enzyme activity test proves that the CitUGT73A78 recombinant protein has broad-spectrum catalytic activity, and can efficiently catalyze the glucosylation of a variety of flavonoids so as to generate the corresponding flavonoids 7-O-glucoside and / or flavonoids 4 '-O-glucoside. An in-vivo transient overexpression test also proves that the CitUGT73A78 gene has a promoting effect on the accumulation of the content of the citrus flavonoid 7-O-glucoside. The invention not only provides a preparation method for the production of flavonoid 4 '-O-glucoside, has the advantages of simplicity, convenience, high catalytic efficiency, low cost, greenness and safety, but also can be applied to nutritional quality improvement and germplasm innovation of citrus fruits.
Owner:ZHEJIANG UNIV

Application of betulinic acid 28-O-beta-D-glucoside in preparation of medicine for preventing and treating skin inflammation

PendingCN120204242AOrganic active ingredientsNervous disorderPityriasis roseaPimple
The invention discloses an application of betulinic acid 28-O-beta-D-glucoside (BA-6 for short) in preparation of a medicine for preventing and treating skin inflammation. The problems that an existing medicine for treating dermatitis is limited in curative effect, slow in effect taking, multiple in side effect, high in long-term use risk, large in individual difference, high in treatment cost, likely to cause immunoreaction and the like are solved. The invention discloses application of BA-6 in prevention and treatment of atopic dermatitis, contact dermatitis, eczema, rash, psoriasis, lupus erythematosus, papule squamous skin disease, pityriasis rosea, seborrheic dermatitis, pemphigus, celestial abscess, acne, tinea corporis, impetigo, SAPHO syndrome, hidradenitis suppurativa, dermatitis caused by drugs, lichen planus, pityriasis rubra pilaris, vitiligo, prurigo nodularis, dermatitis caused by drugs, and the like for the first time. The traditional Chinese medicine composition can be used for treating skin diseases, systemic sclerosis, hidradenitis suppurativa, granulomatous skin diseases, vitiligo, dermatomyositis, chronic skin itch and alopecia areata, and has the technical progress of obviously improving skin erythema, papule, edema, scale, moss and ulceration symptoms.
Owner:SUZHOU UNIV

Application of centella glycosyl transferase gene in catalyzing glycosylation of asiatic acid and madecassic acid

The invention belongs to the technical field of plant genetic engineering, and particularly relates to application of a centella asiatica glycosyl transferase gene in catalyzing glycosylation of asiatic acid and madecassic acid. The nucleotide sequence of the gene is shown as SEQ ID No.1, and the protein coded by the gene can catalyze the C-28 site of asiatic acid and madecassic acid to perform glucose group modification so as to generate asiatic acid monoglucoside and madecassic acid monoglucoside, and preferentially catalyzes madecassic acid. By constructing a metabolic regulation network, the genes are widely and accurately screened, and the glycosylation process of catalyzing asiatic acid and madecassic acid is analyzed; an important reference basis is provided for improving the glycosylation efficiency of asiatic acid and madecassic acid and the yield of asiaticoside and madecassoside in the in-vitro synthesis and industrial production process of the centella asiatica triterpenoid saponin, and an important theoretical support is provided for large-scale production of the centella asiatica active saponin.
Owner:HAINAN UNIVERSITY SANYA NANFAN RESEARCH INSTITUTE

Moisturizing anti-aging nanoemulsion, preparation method thereof and moisturizing essence

The invention relates to the technical field of cosmetics, in particular to moisturizing and anti-aging nanoemulsion, a preparation method thereof and moisturizing essence. The moisturizing and anti-aging nanoemulsion comprises the following raw materials in percentage by mass: 90-99% of an anti-aging component and 1-10% of a moisturizing component, and the anti-aging component comprises the following raw materials in percentage by mass: 1-20% of a glycosylglycerol solution, 0.5-3% of nicotinamide adenine dinucleotide, 0.1-5% of sodium coramate and the balance of a solvent; the moisturizing component comprises ceramide lipidosome. The raw materials in the moisturizing and anti-aging nanoemulsion synergistically exert effects, the moisturizing and anti-aging effects of the moisturizing and anti-aging nanoemulsion are improved, meanwhile, the stability and applicability of the moisturizing and anti-aging nanoemulsion are enhanced, and the moisturizing and anti-aging nanoemulsion is mild and non-irritant to skin and safe to use. The preparation method of the moisturizing anti-aging nanoemulsion is simple in process, high in production efficiency and beneficial to industrial production. The moisturizing essence has more remarkable moisturizing and anti-aging effects by adding the moisturizing and anti-aging nanoemulsion, and is safe to use.
Owner:GUANGDONG HANDSOME BIOLOGICAL TECH CO LTD

Prebiotic dried sweet potatoes and making technology thereof

The invention belongs to the technical field of functional food, and relates to prebiotic dried sweet potatoes and a preparation method thereof. Comprising the following steps: thermally drying the surfaces of cut sweet potato strips / slices, atomizing and spraying alpha-amylase, and then steaming and liquefying; the steaming and liquefying process comprises the following steps: steaming at 55-65 DEG C, and heating to 85-100 DEG C for steaming; performing primary drying, atomizing and spraying an enzyme preparation solution on the surfaces of the primarily dried sweet potato strips / slices, and performing saccharification and glucoside conversion; enzyme preparations in the enzyme preparation solution are beta-amylase and alpha-glucosidase; and carrying out two-stage drying dehydration on the saccharified and glucoside-converted dried sweet potatoes, cooling, and carrying out high-temperature sterilization. The preparation method provided by the invention is simple and convenient in process; rich starch and soluble sugar of the sweet potatoes are converted into bifidus factor isomaltooligosacharide, so that the product has a probiotic function, and the functionality and additional value of the product are increased; and the prepared dried sweet potatoes also have a preservative effect.
Owner:SHANDONG FOOD & FERMENT IND RES & DESIGN INST

Skin-tightening anti-wrinkle essence and preparation method thereof

PendingCN120284764ACosmetic preparationsToilet preparationsPara-hydroxyacetophenoneMicrosphere
The invention belongs to the technical field of cosmetics, and discloses skin-tightening and anti-wrinkle essence. The skin-tightening anti-wrinkle essence is prepared from the following raw materials in percentage by mass: 1.5 to 2.5 percent of acetyl hexapeptide-8, 2.0 to 3.0 percent of palmitoyl pentapeptide-4, 3.0 percent of hydroxypropyl tetrahydropyrantriol, 2.0 percent of lipidosome-coated vitamin C ethyl ether, 0.5 percent of resveratrol PLGA microspheres, 0.8 percent of ceramide NP, 1.2 percent of pachymaran, 5.0 percent of glyceryl polyether-26, 0.3 percent of sodium hyaluronate, 0.5 percent of p-hydroxyacetophenone and 1, 3-propanediol, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate, 0.5 percent of sodium hyaluronate and the balance of water. The 1, 2-hexanediol accounts for 0.6%, and the balance is deionized water. Multi-target anti-wrinkle, deep moisturizing and long-acting repairing are achieved by scientifically compounding active ingredients such as acetyl hexapeptide-8 and palmitoyl pentapeptide-4 and combining a lipidosome wrapping technology and a nano-microsphere slow release technology, the preparation process comprises the steps of lipidosome homogenization, nano-microsphere multiple emulsion method and low-temperature emulsification, the ingredient stability and transdermal efficiency are ensured, and the skin care effect is good. Experiments prove that the essence can significantly improve skin elasticity and reduce wrinkles, and has a significant anti-aging effect.
Owner:BEIJING YUANYANG BIOTECHNOLOGY CO LTD

Method for optimizing fertilization amount of astragalus mongolicus

PendingCN119655037Aimprove qualityOptimize the amount of fertilizer appliedFertilising methodsRoot crop cultivationCalycosinPhosphorus fertilizer
The invention discloses a method for optimizing the fertilization amount of astragalus mongolicus. The method comprises the following steps: dividing land parcels, applying base fertilizer, transplanting astragalus membranaceus, applying nitrogen fertilizer, phosphate fertilizer and potash fertilizer in different dosages to astragalus membranaceus in each land parcel, sampling in the growing period, and measuring astragalus membranaceus root length, root diameter, underground part dry weight, astragaloside content and calycosin-7-glucoside as astragalus membranaceus quality indexes. According to the method, the total yield of astragalus mongholicus is measured in the harvesting period to serve as the yield index of astragalus mongholicus, a comprehensive membership function method is combined with a fertilizer effect equation to optimize the fertilization proportion, and the obtained optimal fertilization formula is that the fertilization amount proportion of N: P: K is 1: 1.5: 2.2, and the element proportion of N: P: K is 5: 2: 12. The yield and quality of astragalus membranaceus can be improved, and popularization significance is achieved.
Owner:NORTHWEST A & F UNIV +2

Mitochondrial energy improving composition based on plant stem cells, application and cosmetics

The invention belongs to the field of daily chemicals, and discloses a mitochondrial energy improving composition based on plant stem cells, application and cosmetics, the composition comprises the following components by weight: 0.0005-1 part of sunflower bud extract; 0.0005 to 1 part of a melissa officinalis extract; and 0.0005 to 1 part of epigallocatechin gallo glucoside or epigallocatechin gallate. According to the composition disclosed by the invention, the sunflower bud extract, the melissa officinalis extract, the epigallocatechin gallyl glucoside or the epigallocatechin gallate are combined, and the combination of the sunflower bud extract, the melissa officinalis extract, the epigallocatechin gallyl glucoside and the epigallocatechin gallate has the effects of obviously improving the cell mitochondrial dysfunction, improving the mitochondrial energy and increasing the content of I-type collagen; the composition can be used as a potential optional scheme of anti-wrinkle active ingredients in cosmetics.
Owner:HUAANTANG BIOTECH GRP CO LTD

Environment-friendly cover plate glass cleaning agent and preparation method thereof

The invention relates to the technical field of glass cleaning agents, in particular to an environment-friendly cover plate glass cleaning agent and a preparation method thereof. The environment-friendly cover plate glass cleaning agent comprises the following raw materials in percentage by weight: 12-20% of inorganic base, 8-12% of a surfactant, 5-8% of a chelating agent, 3-5% of a humectant, 1-3% of an adsorbent, 1-3% of a dispersing agent, 0.3-1% of a buffering agent and the balance of deionized water, the surfactant is dodecyl glucoside and dodecyl ethyoxyl sulphobetaine, and the weight range ratio of the dodecyl glucoside to the dodecyl ethyoxyl sulphobetaine is (3-1): 1; the chelating agent is one or more of sodium gluconate, sodium polyaspartate and sodium polyepoxysuccinate. According to the present invention, the degradable surfactant and the degradable chelating agent are adopted, and the dispersant is added to modify the nanometer titanium dioxide, such that the low pollution property is achieved while the high decontamination efficiency and the anti-fingerprint ability are considered.
Owner:DONGGUAN JINGBO PHOTOELECTRIC BIT CO

Method for biosynthesizing epigallocatechin gallate glucoside

The invention discloses a method for biosynthesizing epigallocatechin gallate glucoside, and belongs to the technical field of biocatalytic synthesis. According to the method, a sucrose phosphorylase mutant is adopted as a catalyst, the sucrose phosphorylase mutant is subjected to single-point mutation or combined mutation on the basis of an amino acid sequence SEQ ID NO.1, and the enzyme activity of the sucrose phosphorylase is improved through mutation; the mutant is utilized to realize efficient catalytic synthesis of epigallocatechin gallate glucoside, and in the whole catalytic process, the synthesis method is mild in condition, simple to operate, short in reaction time and high in catalytic efficiency, and has a good application prospect.
Owner:NANJING TECH UNIV

Pressure-resistant and anti-permeation deep-sea intrinsic antifouling polyurethane as well as preparation method and application of pressure-resistant and anti-permeation deep-sea intrinsic antifouling polyurethane

The invention discloses a pressure-resistant and anti-permeation deep sea intrinsic antifouling poly-fatty ammonia glycol as well as a preparation method and application of the pressure-resistant and anti-permeation deep sea intrinsic antifouling poly-fatty ammonia glycol. The deep-sea intrinsic antifouling poly-fatty amino vinegar comprises polymer soft segments, antibacterial hard segments and polyiso-oxoacid chain segments, wherein the polymer soft segments, the antibacterial hard segments and the polyiso-oxoacid chain segments are alternately distributed; wherein the antibacterial hard segment comprises a barking group two-fat unit. The antibacterial hard segment in the deep-sea intrinsic antifouling poly-fatty ammonia endows the poly-fatty ammonia glucoside with a fouling organism contact killing function, and the barking ring and the poly-fatty ammonia glucoside synergistically endow the deep-sea intrinsic antifouling poly-fatty ammonia glucoside with high pressure resistance and high permeability; meanwhile, the deep-sea intrinsic antifouling poly-fatty ammonia glucoside is suitable for surface antifouling of thousand-deep-sea environment equipment, can resist deep washing high pressure and seawater permeation, and can effectively prevent adhesion of deep washing bacteria and fouling organisms.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI

Preparation method for enhancing inhibitory activity of lonicera caerulea juice xanthine oxidase through fermentation of plant lactobacillus

According to the preparation method disclosed by the invention, the whole fruit juice of the lonicera caerulea (which retains fruit residues) is fermented by virtue of the plant lactobacillus KLDS1.0391, KLDS1.0320 or KLDS1.0368, so that the xanthine oxidase (XO) inhibition activity is remarkably improved. After fermentation, the XO inhibition rate is increased to 48-50.87% (the content of unfermented juice is 31.21%), the total phenol content is increased by 15-24.3%, and the contents of main XO inhibitors in the lonicera caerulea: cyanidin-3-O-glucoside (IC50 = 115.28 [mu] M), cyanidin-3, 5-diglucoside (IC50 = 116.34 [mu] M), peonidin-3-glucoside (IC50 = 105.34 [mu] M), quercetin (IC50 = 88.75 [mu] M), catechin (IC50 = 110 [mu] M) and caffeoylquinic acid (IC50 = 250.35 [mu] M) are remarkably increased. Wherein the quercetin content is increased by 73.8% at most (KLDS1.0320 strain fermentation is performed for 24 hours), and the XO inhibition rate is increased from 31.21% to 50.87%. Technical support is provided for development of a natural XO inhibitor and a functional fermented beverage, so that a new thought is provided for functional fermented juice with lonicera caerulea as a key component.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Screening, verification and detection method for allergen substances in carthamin yellow injection

PendingCN119936224AOrganic active ingredientsComponent separationCarthamus yellowRutin
The invention discloses a screening method of allergen substances in a carthamin yellow injection, a verification method of the allergen substances in the carthamin yellow injection, a detection method of the allergen substances in the carthamin yellow injection and a production process of the carthamin yellow injection. The screening method of the allergen substances in the carthamin yellow injection comprises the following steps: S1, extracting components in the carthamin yellow injection; s2, separating and screening components in the extract by adopting a high performance liquid chromatography-ultraviolet detection-mass spectrum and human serum albumin combined detection technology; and S3, screening out a substance which can be combined with the HSA, and determining the substance as a sensitization hapten substance which has sensitization potential. The invention aims to detect that the 6-hydroxykaempferol-3-rutin-6-glucoside has HAS binding characteristic, hapten attribute and sensitization potential, and can provide basis for process improvement of carthamin yellow injection and reduce the sensitization risk in clinical application.
Owner:CHINA INST FOR RADIATION PROTECTION

Sunscreen composition as well as preparation method and application thereof

The invention relates to a sunscreen composition as well as a preparation method and application thereof. The sunscreen composition comprises a coco-glucoside-coconut oil alcohol compound, polyethylene glycol stearate, dextrin palmitate, butyl octanol salicylate and titanium dioxide. The dextrin palmitate, the butyl octanol salicylate and the coco-glucoside-coconut oil alcohol compound in the composition are matched with one another, so that the composition has excellent wetting, dispersing and suspending effects on the titanium dioxide powder, the sunscreen performance of the composition is greatly improved, and the composition has a synergistic effect in the aspects of improving the stability of the composition and improving the sunscreen effect. Meanwhile, the coco-glucoside-coconut oil alcohol compound can be compatible with polyethylene glycol stearate, so that a sunscreen product further prepared from the composition does not need to be removed by a cleaning product, and the sunscreen product can be washed with clear water.
Owner:GUANGZHOU HAIGUI PAPA BIOTECHNOLOGY CO LTD

Herbal amino acid face cleaning mousse

According to the herbal amino acid face cleaning mousse disclosed by the invention, performance comparison is carried out on high and low addition amounts of various surfactants, a data basis is provided for compounded surfactants, and then a face cleaning mousse system is constructed by utilizing a compounded optimal surfactant group; the cleansing mousse is good in stability, rich and fine in foam, good in washing smoothness, easy to wash cleanly and low in water loss rate, skin dryness after use is reduced, and diversified requirements of consumers are met. By optimizing the dosage of glycerol and 1, 3-butanediol, the foam texture is better, and the foam is more elastic. By adding the jojoba oil, the irritation to the skin and eyes is minimized while the facial greasy dirt is mildly washed off, and obvious moistening and moisturizing effects are brought. By adding raspberry ketone and raspberry ketone glucoside, a preservative-free system is constructed, and the anti-oxidation effect is achieved; by means of the herbal extracts, product irritation is reduced, damage of free radicals is prevented, the resistance of skin is improved, and the product can be applied to various skin types better.
Owner:NANJING COLLEGE OF CHEM TECH

Whitening and freckle-removing essence water and production process thereof

The invention discloses a whitening and freckle-removing essence which comprises the following components: a calendula extract, pure water, 1, 2-pentanediol, methylpropanediol, carbomer, arginine, nicotinamide, a freckle-removing essence, a natural plant penetration enhancer, hydroxyethyl piperazine ethanesulfonic acid, small-molecule ellagic acid, dipropylene glycol, 1, 2-propylene glycol, ethanol and water. The composition is prepared from 1, 2-hexanediol, caprylyl glycol, ethylhexylglycerin, raspberry ketone glucoside and a PEG / PPG-17 / 6 copolymer. The invention further discloses a production process of the whitening and freckle-removing essence water. The invention has the following advantages: with pure natural plants as a main product, the skin has obvious change after being used for a week, specifically, pregnancy spots, sunburn, chloasma, pigmentation after inflammation and other color spots on the face can be reduced and faded, the face skin can be whitened, the face is mild and non-irritating, and the effects of improving uneven skin color, brightening skin color and the like can be achieved.
Owner:FEILANG BIOTECHNOLOGY (HUBEI) CO LTD

Leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite

The invention relates to the technical field of aquaculture, in particular to a leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite. The Leiocassis longirostris intestinal health functional additive comprises the following functional components: chondroitin sulfate, N-acetyl-D-galactosamine, 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4'- The composition is prepared from the following raw materials: 4, 6-dihydroxyflavone, polydatin, ascorbic acid, glucoside, arabinogalactan, 3-O-beta-D-galactopyranosyl-L-arabinose, tyramine, 4A-hydroxytetrahydrobiopterin, hyaluronic acid and 3-mercapto-2-butanol. According to the technical scheme, the technical problem that an existing probiotic viable bacterium preparation is difficult to meet the intestinal health management requirement in intensive culture of the leiocassis longirostris can be solved. Compared with the prior art, the scheme is more efficient, stable and safe, healthy development of the Leiocassis longirostris breeding industry can be effectively promoted, and the method has ideal application and popularization prospects.
Owner:FISHERIES INST SICHUAN ACADEMY OF AGRI SCI

Preparation method of fusidic acid cream

The invention provides a preparation method of fusidic acid emulsifiable paste, and relates to the field of pharmaceutical preparations, and the preparation method comprises the following steps: step 1, preparation of fusidic acid nanoparticles, step 2, preparation of an oil phase of the emulsifiable paste, step 3, preparation of a water phase of the emulsifiable paste, step 4, emulsification, and step 5, mixing. According to the fusidic acid nanoparticles, firstly, a composite carrier is prepared, then fusidic acid, PLGA, the composite carrier and absolute ethyl alcohol are mixed, a nanoparticle oil phase is obtained, then PVA, PVP, sodium dodecyl glucoside sulfonate and dipotassium ethylenediaminetetraacetate are mixed with deionized water, a nanoparticle water phase is obtained, and finally a nanoparticle suspension is obtained through mixing. The fusidic acid emulsifiable paste prepared by the method can effectively solve the problems that the traditional emulsifiable paste bulk drugs are easy to agglomerate, the drug molecule particle size is large and the like, and the transdermal absorption rate and bioavailability of fusidic acid are improved, so that the antibacterial effect is enhanced.
Owner:CHONGQING CONQUER PHARML

Anti-aging composition for strengthening skin supporting network and application of anti-aging composition

The invention relates to an anti-aging composition for strengthening a skin supporting network and application thereof, and the anti-aging composition comprises the following components: a golden camellia flower extract, a saffron crocus extract, camellia seed oil, tranexamic acid and epigallocatechin gallate glucoside, the weight ratio of the golden camellia flower extract to the saffron crocus extract to the camellia seed oil to the tranexamic acid to the epigallocatechin gallate glucoside is (0.1 to 5) to (0.01 to 5) to (0.1 to 10) to (0.01 to 2) to (0.001 to 0.1). The composition provided by the invention can synergistically strengthen a skin support network and comprehensively improve skin elasticity and compactness by promoting growth of two core structural proteins and three macromolecular adhesives of skin, and is mild, non-irritant and suitable for people with sensitive skin.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Feed additive for synergistically improving oxidative stress resistance of broiler chickens based on oleuropein-luteoloside-maslinic acid ternary combination and application of feed additive

The invention discloses a feed additive for synergistically improving oxidative stress resistance of broiler chickens based on oleuropein-luteoloside-maslinic acid ternary combination and application of the feed additive, the feed additive is the olea europaea leaf extract, the total polyphenol content of the feed additive is about 52%, the total flavone content is 7%, and the total flavone content is 5%. The feed is mainly composed of oleuropein, luteolin-7-beta-glucoside and maslinic acid, the oleuropein, the luteolin-7-beta-glucoside and the maslinic acid are sequentially added in a molar ratio of 6: 1: 1 to generate a synergistic anti-oxidative stress effect, and when the feed is applied to breeding on the basis of corn-soybean daily ration of broilers, the daily gain of the broilers can be obviously increased, the feed conversion ratio is reduced, and the feed conversion rate is increased. The intestinal micro-ecological health, the anti-oxidative stress effect and the organism immunity are improved, and the infection rate and the death rate of intestinal diseases such as diarrhea of broilers are reduced. The product has the advantages of being simple and convenient to prepare and use, free of toxic and side effects, beneficial to broiler chicken growth and human health, free of the problems of drug resistance, drug residues and the like, and capable of promoting chicken meat quality improvement and the like.
Owner:INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY

Remediation agent for high-concentration hexavalent chromium contaminated soil and preparation method and remediation method thereof

The invention discloses a remediation agent for high-concentration hexavalent chromium polluted soil and a preparation method and a remediation method thereof, and belongs to the technical field of soil pollution remediation. The remediation agent for the high-concentration hexavalent chromium contaminated soil comprises an acidic precursor, an iron-sulfur reducing agent and a synergist, the acidic precursor comprises organic acid and propylene glycol alginate; the iron-sulfur reducing agent comprises an iron-based reducing agent and a sulfur-based reducing agent; the synergist is prepared from sophorolipid and alkyl glucoside. The remediation agent can be used for high-concentration hexavalent chromium contaminated soil, hexavalent chromium in the soil is exposed in a Cr < 6 + > ion form as much as possible by replacing the hexavalent chromium in the soil, then the hexavalent chromium is converted into trivalent chromium by using a reducing agent, and the removal efficiency of the hexavalent chromium reaches up to 99.6%. In addition, the soil remediation agent is simple in use mode, rapid and thorough in reaction and lasting in effect.
Owner:LINYI UNIVERSITY +1

Anti-aging composition for promoting communication between skin cells and application of anti-aging composition

The invention relates to an anti-aging composition for promoting skin intercellular communication and application thereof, and the composition comprises the following components: a camellia nitidissima flower extract, a bacillus fermentation product, an European basswood extract and safflower glucoside, the weight ratio of the golden camellia flower extract to the bacillus fermentation product to the European basswood extract to the safflower glucoside is (1-10): (1-8): (1-6): (0.1-1). The anti-aging composition provided by the invention can promote the activity of skin communication cells, enhance intercellular communication and interaction, give full play to the biological function of cells, and achieve the anti-aging effect; the composition has the effects of removing wrinkles, tightening, smoothing and repairing, can inhibit damage of cortisol to skin barriers, achieves the effects of repairing and relieving mood pressure, and can achieve the optimal effects of removing wrinkles, tightening, smoothing and repairing due to mutual synergism of the components.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Whitening compound as well as preparation method and application thereof

The invention discloses a whitening compound as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The structural formula of the whitening compound is as follows: # imgabs0 #, R1 and R2 independently comprise alpha glucoside, beta glucoside or phenolic hydroxyl groups, and R1 and R2 are not phenolic hydroxyl groups at the same time. The whitening compound has higher stability, is not easy to generate self-oxidation reaction, and is beneficial to prolonging the shelf life of the product and prolonging the durability of the whitening effect; moreover, the whitening compound is suitable for sensitive skin, and can reduce skin irritation and reduce adverse reactions such as red and swollen, stabbing pain, dryness and the like; in addition, the whitening compound can promote proliferation of beneficial bacteria on epidermis, and can improve or improve the skin whitening effect to a certain extent.
Owner:OSMUN BIOLOGICAL CO LTD

Pressure-sensitive adhesive composition, pressure-sensitive adhesive sheet, laminate, and glucan derivative

The present invention provides a novel pressure-sensitive adhesive composition including a glucan derivative. The pressure-sensitive adhesive composition of the present invention includes a glucan derivative G having a glucoside bond A, and a glucoside bond B having a different bonding form from the glucoside bond A. The glucoside bond A is, for example, a 1,6-glucoside bond. A pressure-sensitive adhesive sheet 1 of the present invention is formed from the pressure-sensitive adhesive composition. A laminate 10 of the present invention includes the pressure-sensitive adhesive sheet 1 and a substrate sheet 2.
Owner:NITTO DENKO CORP

Metal degreasing agent and preparation method thereof

The invention discloses a metal degreasing agent and a preparation method thereof, and belongs to the technical field of degreasing. Comprising lipase, protease, short-chain fatty acid methyl ester ethoxylate sodium sulfonate, cocamidopropyl betaine, alkyl glucoside, sodium silicate, sodium metasilicate, sodium citrate, disodium ethylene diamine tetraacetate, calcium formate, polyvinyl alcohol-sodium alginate microcapsules, a polyoxyethylene polyoxypropylene block copolymer, sodium carboxymethyl cellulose and water. And the polyvinyl alcohol-sodium alginate microcapsule exists in the metal degreasing agent as a carrier of the lipase and the protease. According to the metal degreasing agent, a microcapsule protection structure is used in the metal degreasing agent, the two technical problems of enzyme-surfactant compatibility and enzyme-alkaline environment compatibility which are difficult to solve for a long time in an industrial degreasing agent are solved, the degreasing agent is easy to actually operate, special equipment is not needed, a traditional degreasing agent can be directly replaced, and the metal degreasing agent is suitable for industrial application. Good market application prospects are realized.
Owner:ZHENJIANG CHANGHUI NEW MATERIAL CO LTD +1

A composition with moisturizing and repairing effects, preparation method and application thereof

The present invention belongs to the technical field of cosmetics, and discloses a composition with moisturizing and repairing effects, a preparation method thereof and an application thereof. The composition of the present invention comprises a xylitol moisturizer, 4D hyaluronic acid, a peach resin extract and hydroxyphenyl propionamide benzoic acid, the xylitol moisturizer comprises at least one of xylitol, dehydrated xylitol and xylitol glucoside, and the 4D hyaluronic acid comprises at least one of sodium hyaluronate, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate and sodium hyaluronate cross-linked polymer. The present invention rationally compounds the xylitol moisturizer, 4D hyaluronic acid, peach resin extract and hydroxyphenyl propionamide benzoic acid, can locate the skin at different layers, effectively increase the moisture content of the epidermis and dermis, and maintain the hydration state of the skin, while repairing damaged keratinocytes, enhancing the barrier function of the skin, and reducing the loss of water, thereby having good moisturizing and repairing effects.
Owner:GUANGZHOU HUANYA COSMETIC SCI & TECH CO LTD