1050 results about "Rutin" patented technology

The invention discloses a mushroom cultivating method utilizing residues of sophora flower buds after extraction of rutins. The mushroom cultivating method utilizing the residues of the sophora flower buds after the extraction of the rutins comprises processing burdening, namely weighing cultivation raw materials which comprise, based on the weight percent, cotton seed hull of 42-60%, the residues of the sophora flower buds after the extraction of the rutins of 28-40%, bran of 10-20%, gypsum of 0.6-2%, calcium superphosphate of 0.3-1%, carbamide of 0.2-1% and sugar of 0.8-2% and adding water into the cultivation raw materials after uniform mix of the cultivation raw materials to enable water content of the cultivation raw materials to achieve 55-65%; bagging and sterilizing after the burdening processing; inoculating and cultivating hypha; building a shed and earthing up; coloring; and managing fruiting. The mushroom cultivating method utilizing the residues of the sophora flower buds after the extraction of the rutins has the advantages of being simple in operation, capable of cultivating the mushroom by adding small amount of nutritional ingredients, quick in spawn runing, low in production cost and capable of effectively utilizing by-product residues in phytoextraction industries in a maximum limit and achieving sustainable development.

A method for extracting and refining rutin comprises the following steps of (1) extraction: smashing raw materials, adding organic solvent into the smashed raw materials, performing extraction for 2-4 times, mixing extracting solution and concentrating the mixed extracting solution to thick extract with organic solvent content smaller than or equal to 5wt%; (2) alkali dissolution-acid sediment: adding alkaline water into the thick extract, then heating the mixture and stirring, filtering the heated mixture, regulating pH of alkaline filtrate to be 3-4, standing, filtering, drying to obtain a rutin pure product; and (3) mother liquor treatment: enabling obtained acid mother liquor to penetrate through a chromatographic column filled with resin, after the acid mother liquor penetrates through the chromatographic column, firstly using deionized water to wash a column bed until outflow liquid is neutral and colorless, introducing eluent into the chromatographic column and collecting eluate until outflow liquid is colorless, concentrating the eluate to the volume which is 5-10% of the original volume in a pressure reduction mode, cooling the concentrated eluate to achieve crystallization, filtering, using the deionized water to elute a filter cake, and drying the eluted filter cake to obtain a mother liquor rutin product. The prepared rutin is high in yield and purity, and the quality of the rutin reaches the international standard.

The invention relates to a method for extracting suaeda salsa flavone and measuring content of flavone in suaeda salsa. The method comprises the following steps: 1), collecting the suaeda salsa, drying the suaeda salsa and crushing the suaeda salsa; with ethanol as an extractant, soaking the suadeda salsa and carrying out microwave-assisted extracting; filtering; extracting with petroleum ether; transferring the ethanol layer to a macroporous adsorption resin layer; and eluting with water and ethanol aqueous solution sequentially; collecting the eluant, and pressurizing and concentrating the eluant to obtain flavone compound extract; 2), with rutin as a contrast, preparing standard solution with different concentration gradients; measuring the chromatographic peak area at the wavelength of 360nm through a high efficiency liquid chromatography to form flavone content contrast reference; measuring the chromatographic peak area of the to-be-measured solution; obtaining the flavone content of the to-be-measured solution according to the flavone content contrast reference; and obtaining the content of the flavone in the suaeda salsa according to the dilution multiple of the to-be-measured solution. According to the method provided by the invention, soaking and microwave-assisted extracting are adopted to extract flavone, and the content of the flavone is measured by chromatography, so that the method is simple and the solvent is easily available. Besides, the obtained flavone is high in content, and has the physiological and pharmacological activities such as antiviral activity, antioxidant activity, anti-ageing activity and the like.

The invention discloses a total chromocor extract from traditional medicine citrus fruit and preparing method, which is characterized by the following: comprising pomelo ped glycosides, new orange peel glycosides, orange peel glycosides, pomelo ped rutin, derivant and so on; choosing one or several methods from solvent extraction, solvent extraction process, macroreticular absorption resin method, lead salt precipitation method, column chromatography, supercritical fluid chromatography, liquid-liquid counter-current partition chromatography and so on; producing extract; setting percentage content of various chromocor element at 5-100%(w/w) in the extract; counting 5-100%(w/w) of pomelo ped glycosides, new orange peel glycosides, orange peel glycosides in total chromocor content.

The present invention discloses a troxerutin medicine with content of active matter 3', 4', 7-trihydroxy rutin over 90%. The active matter has molecular expression of C33H42O19 and molecular weight of 742.68. The preparation process includes the reaction stage comprising hydroxyethylation reaction, hot filtering and concentration; and the refining stage comprising heating, cooling, filtering and drying. The preparation process has high yield, low cost, simple and fast operation and high product quality, and is suitable for preparation of different medicine preparation forms.

The invention relates to quercetin-3-O-acyl ester and a preparation method thereof and belongs to the technical field of pharmaceutical chemistry. The preparation method comprises the following steps: taking cheap rutin as a starting raw material and preparing a quercetin-3-O-acyl ester compound through benzylation, hydrolysis under the acidic conditions, esterification, catalytic hydrogenolysis and other reactions. The method has the characteristics of good selectivity, mild reaction condition, high yield, low cost, simplicity and convenience in operation, easiness in industrial production and the like. In addition, the inhibitory effect of the obtained quercetin-3-O-acyl ester on human esophageal squamous carcinoma cells EC9706, human prostatic cancer cells PC-3 and human gastric cancer cells MGC-803 is remarkably superior to that of quercetin; and the quercetin-3-O-acyl ester can be used in the field of foods and medicines and is possible to develop into a new candidate drug for treating tumor.

The invention discloses an extractive of Taxus chinensis var.mairei leaves and a preparation method. The extractive is a straw yellow powder. The powder contains sciadopitysin the weight content of which is 65-70 percent; the sciadopitysin contains the following five components: 3-O-rutin-quercetol, 3-O-rutin-campherol, 3-O-rutin-myricetin, 7-O-glucose-campherol and 7-O-glucose-quercetol, and the total weight content of the five components in the sciadopitysin is 40-60 percent. The extractive is prepared by the preparation method comprising the steps of baking, crushing and screening, immersing into an alcohol dissolvant, ultrasonically extracting while stirring, decompressing and concentrating an extracting solution to remove alcohol, extracting with chloroform and degreasing, water phase concentrating and drying by taking fresh Taxus chinensis var.mairei leaves as raw materials. The extractive of Taxus chinensis var.mairei leaves has the functions of improving heat microcirculation, resisting arrhythmia, lowering myocardial oxygen consumption and the like and having the therapeutic and health-care function on diseases of cardiovascular system; and the preparation method has low energy consumption, short extracting time, few impurities and higher extraction efficiency.

The invention relates to an action of ferulic acid on enhancing the drug effect of some medicaments and a purpose thereof, wherein the medicaments mainly comprise alkaloid medicaments including matrine, kushenin, sophocarpine, hyoscyamine, narceine, hanfangchin A, jamaicin, morphine, codeine, evodiamine, strychnine, catharanthine, vincristine, taxol, verticine, peimine, peiminine, ephedrine, pseudoephedrine, wilfordine, triptolide, tripdiolide and the like, and flavonoid medicaments including puerarin, ginsenoside, ginsengenin, mangiferin, scutelloside, alkannin, meletin, rutin, hesperidin, daidzin, soybean isoflavone, daidzein, carthamin, catechin and the like. The ferulic acid and the medicaments can form a compound or a medicament compound, or the ferulic acid and the medicaments can generate a chemical reaction (including salification, esterification, amidation, ketonization, etherification and the like), and/or the ferulic acid and the medicaments can generate a synergistic effect and an additive effect.

The invention discloses an electrochemical method based on a graphene-modified electrode for simultaneous determination of rutin and quercetin. The graphene-modified electrode is used as a working electrode, and cyclic voltammetry and differential pulse voltammetry are adopted for simultaneous determination of the rutin and the quercetin. Since grapheme is used as a modifying material for the electrode, electrochemical separation of two Chinese flavonoids, the rutin and the quercetin can be achieved on the modified electrode, and the contents of the rutin and the quercetin in sophora flower bud can be determined simultaneously through direct electrochemical determination.

A UGT2B inhibitor capable of increasing the bio-availability of a drug, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: capillarisin, isorhamnetin, β-naphthoflavone, α-naphthoflavone, hesperetin, terpineol, (+)-limonene, β-myrcene, swertiamarin, eriodictyol, cineole, apigenin, baicalin, ursolic acid, isovitexin, lauryl alcohol, puerarin, trans-cinnamaldehyde, 3-phenylpropyl acetate, isoliquritigenin, paeoniflorin, gallic acid, genistein, glycyrrhizin, protocatechuic acid, ethyl myristate, umbelliferone, PEG (Polyethylene glycol) 400, PEG 2000, PEG 4000, Tween 20, Tween 60, Tween 80, BRIJ® 58, BRIJ® 76, Pluronic® F68, Pluronic® F127, and a combination thereof. A UGT2B enhancer capable of enhancing a clearance rate of morphine-like analgesic agents, is a compound in a free base or a pharmaceutically acceptable salt form that is selected from the group consisting of: nordihydroguaiaretic acid, wogonin, trans-cinnamic acid, baicalein, quercetin, daidzein, oleanolic acid, homoorientin, hesperetin, narigin, neohesperidin, (+)-epicatechin, hesperidin, liquiritin, eriodictyol, formononetin, quercitrin, genkwanin, kaempferol, isoquercitrin, (+)-catechin, naringenin, daidzin, (−)-epicatechin, luteolin-7-glucoside, ergosterol, rutin, luteolin, ethyl myristate, apigenin, 3-phenylpropyl acetate, umbelliferone, glycyrrhizin, protocatechuic acid, poncirin, isovitexin, 6-gingerol, cineole, genistein, trans-cinnamaldehyde, and a combination thereof.

The invention discloses a buckwheat sprout seedling dish and a preparation method thereof, belonging to the field of foods. The preparation method of the buckwheat sprout seedling dish comprises the steps of seed selection, sterilization, seed soaking, sowing, sprouting, harvesting and the like, and the water content of the obtained buckwheat sprout seedling dish is 80% to 90%. In the invention, the buckwheat sprout seedling dish made by buckwheat after sprouting has the savory taste of buckwheat sprouts and is rich in flavonoid compounds, such as rutin and the like, and 18 kinds of amino acids necessary to a human body simultaneously, the mineral content of the buckwheat sprout seedling dish is higher than that of common buckwheat kernels, the activity of nutritional ingredients is reinforced, and the nutritional ingredients are easy for the human body to absorb; by eating the buckwheat sprout seedling dish frequently, the immunity of the human body can be enhanced, and the health of the human body is strengthened.

The present invention belongs to the field of plant extraction, and specifically relates to a method for preparing quercetin by adopting flos sophora and producing rhamnose by using the quercetin preparation waste liquid. The technical problem solved by the method is to provide a completely new process for producing quercetin and rhamnose. The method specifically comprises the following steps: A, taking a proper amount of flos sophora, crushing, and adopting saturated and clarified lime water to extract rutin; B, adopting the rutin extracted in the step A to carry out hydrolysis to prepare quercetin; C, carrying out fermentation on the waste liquid from the step B to prepare a rhamnose crude product; and D, adopting methanol to separate glucose in the rhamnose crude product in the step C to prepare the rhamnose fine product. The method has characteristics of high yield, low cost, simple process, low pollution and low energy consumption, wherein the by-product rhamnose is produced so as to achieve a resource saving purpose.

The invention discloses a preparation method of buckwheat bread ready-mixed powder containing buckwheat bran dietary fiber and rutin, comprising the following steps: a. bran defatting; b. smashing; c. dietary fiber extracting; d. dry packing; e. rutin extracting; f. separating and purifying; g. vacuum-concentrating; h. quick-freezing; i. vacuum freeze-drying; j. packaging; and k. ready-mixed powder preparing. Compared with other ready-mixed powders, the ready-mixed powder prepared by the invention is added with the active nutrient extract of buckwheat, and the bread made thereof is safe to consume and has buckwheat dietary fiber and rutin; the long-term consumption of the bread can help to improve body immunity and enhance human health.

The present invention provides a method of suppressing fading of a tar colorant. More specifically, the present invention provides a method of suppressing a tar colorant fading phenomenon that occurs specifically in compositions containing (a) the tar colorant, and (b) at least one of reducing sugars, ascorbic acid compounds, or metals. This method can be attained by mixing (c) at least one selected from the group consisting of isoquercitrin, enzymatically modified isoquercitrin, rutin, enzymatically modified rutin, Chinese bayberry extract, and rosemary extract into such a composition, thus making the component (a), the component (b) and the component (c) coexist. The present invention further provides a composition for which fading of a tar colorant is suppressed using the above method, more specifically a composition containing at least one of reducing sugars, ascorbic acid compounds, or metals in addition to the tar colorant.

The invention discloses a novel method for extracting rutin from pagodatree flower bud, and specifically relates to a method combining an ultramicro powder technology and continuous countercurrent ultrasound. The method comprises the following steps: after adding alkali liquor into superfine-grinded pagodatree flower bud, filtering to obtain leach liquor after continuous countercurrent ultrasonic extraction; repeatedly extracting the filter residue twice; combining the filtrate; adjusting the PH and carrying out acid precipitation; standing; filtering to obtain a rutin coarse extract; adding methanol to fully dissolve the rutin coarse extract; then, adding hot distilled water to stir; naturally cooling till rutin is recrystallized and separated out; repeatedly crystallizing twice; and then filtering and drying the crystals finally obtained to obtain high purity rutin. According to the novel method provided by the invention, least solvent is used to realize the maximum solubility, so that the novel method is high in extraction rate, short in extraction time and low in extraction cost, and is suitable for industrial production.

A process for preparing a rutin-enriched composition from plant biomass comprises extraction with an aqueous solution, and precipitation. An enzyme preparation, such as naringinase, is used for the transformation of rutin to higher value compositions containing increased proportions of isoquercitrin and quercetin.

A buckwheat tea is prepared from raw buckwheat grains through wetting, high-temp and-pressure baking, removing shell, and roasting or puffing. Its advantage is less loss of nutrients including rutin.

The invention discloses a preparation method for a film coating antistaling agent for rosa roxburghii tratt, and a matching method for low-temperature fresh keeping. The antistaling agent is prepared by using the following raw materials: coating agent sodium alginate, agar, tamarind seed gum, guargum, surface acting agent, i.e., sucrose fatty acid ester, preservative agent, i.e., calcium propionate, ethylene inhibitor, 1-MCP, gene revulsant, i.e., diethyl aminoethyl hexanoate and water; the coating agent and the surface active agent are respectively heated with water to dissolve and then mixed, then the preservative agent, the ethylene inhibitor and the gene revulsant are added in, finally, the water with determined capacity is added and then evenly stirred while the mixture is still hot,so as to obtain the antistaling agent. The antistaling agent is put in the vessel when in use, then the dried fruits of the rosa roxburghii tratt are poured into the antistaling agent, dipped and coated, and then aired, and are stored in a cold storage warehouse with a temperature of 0 DEG C to 1 DEG C and a relative humidity of 60 percent to 70 percent. The rosa roxburghii tratt after being treated by the antistaling agent is not easy to be rotten, the content of the Vc, the SOD and the rutin is reduced little with the content of the titrated acidity, the fresh-keeping time reaches for 4 months to 6 months, and the antistaling agent facilitates storage and processing of the rosa roxburghii tratt and also improves the economic value of the rosa roxburghii tratt.

A wild buckwheat wine for softening blood vessel and delaying sanility is prepared from wild buckwheat through choosing raw materials, proportionally mixing, distilling, cooling, adding yeast, and fermenting in cellar.

The invention discloses application of bioflavonoids or polyphenol compounds to preventing and treating Parkinson diseases. The bioflavonoids or polyphenol compounds can be selected from kaempferol-3-O-rutinoside, dehydrated carthamin yellow B, 6-hydroxyl kaempferol-3, 6-dioxygen glucoside, (2S)-4', 5-dihydroxyl-6, 7-dioxygen flavonone glucoside, rutin, quercetin, vanillina or isovanillin. Through large amount of experiments, the bioflavonoids or polyphenol compounds have activity of interacting with protein DJ-1 related to the Parkinson diseases. Through further experiments, the bioflavonoids or polyphenol compounds have pharmaceutical activities for resisting oxidative stress, preventing apoptosis of PC12 cells or primary nerve cells induced by the oxidative stress, inhibiting active oxygen generation in cells, improving activity of tyrosine hydroxylase, and the like, and can be used for preventing or treating the Parkinson diseases.

A flavonoid solubilization agent capable of highly solubilizing flavonoids such as isoflavone, baicalin, rutin and naringin whose solubility is generally low; and a method of effecting the above solubilization. Flavonoids can be solubilized by causing a flavonoid and soybean saponin and/or malonyl isoflavone glycoside to be co-present in an aqueous medium.