86 results about "Hesperidin" patented technology

The invention discloses an application of a CsHCT1 gene in increasing the content of citrus flavonoids, belongs to the technical field of agricultural biological genetic engineering, and provides an application of the CsHCT1 gene in increasing the content of citrus flavonoids, and the nucleotide sequence of the CsHCT1 gene is as shown in SEQ ID NO.1. The invention further discloses an application of the CsHCT1 gene in increasing the content of citrus flavonoids. The invention also discloses a method for improving the flavone compound of the citrus peel by using the CsHCT1 gene. The method comprises the following steps: cloning the citrus CsHCT1 gene; a CsHCT1 overexpression vector is constructed; transforming the overexpression vector to agrobacterium tumefaciens to obtain an agrobacterium tumefaciens liquid; and injecting the CsHCT1 gene into the citrus fruit to obtain the CsHCT1 gene overexpressed citrus fruit. A new choice is provided for increasing the flavonoid compounds in the citrus peel, the content of vicenin-2 and / or hesperidin in the citrus peel is effectively increased, and the application has great application value for cultivating new functional citrus varieties and accelerating the breeding process.

The invention discloses a plant-sourced anti-allergy soothing composition and application thereof, and belongs to the field of cosmetic processing.The plant-sourced anti-allergy soothing composition is prepared from hydrolyzed corn starch, saururus chinensis extract, carrot root extract and water-soluble hesperidin. Active ingredients of plant sources are deeply studied, and the anti-allergy soothing composition has the advantages that the plant-sourced anti-allergy soothing composition is prepared from the hydrolyzed corn starch, the saururus chinensis extract, the carrot root extract and the water-soluble hesperidin; a series of plant extracts with a synergistic effect are screened out, the plant-source multi-dimensional composition for relieving itching and repairing red is successfully researched and developed, and through the synergistic effect of the hydrolyzed corn starch, the saururus chinensis extract, the carrot root extract and the water-soluble hesperidin, the composition has the effects of relieving and repairing skin in a multi-dimensional mode, relieving itching and repairing red. In addition, the composition can repair the skin barrier for a long time and improve the tolerance of the skin, and meanwhile, the composition has good safety and stability and is suitable for various skin types, especially sensitive skin.

This invention discloses a quality control method for an anti-snoring oral liquid and its application, belonging to the field of traditional Chinese medicine quality testing technology. The method includes thin-layer chromatography identification of Gleditsia sinensis thorns, Scrophularia ningpoensis, and Glycyrrhiza uralensis, as well as high-performance liquid chromatography (HPLC) determination of hesperidin content. By optimizing pretreatment, developing solvent, and colorimetric conditions, this invention achieves efficient and specific identification and quantification of multiple components in the compound preparation. The method is highly specific, produces clear spots, has good separation, and is tolerant to a wide temperature and humidity range (2-40℃, 20%-75%RH), requiring no strict environmental control, significantly improving detection efficiency and providing a reliable basis for establishing quality standards for this preparation.

The application provides a kind of zhangtou red pericarpium citri reticulatae UPLC quantitative fingerprint detection method, belongs to the quality detection technical field of traditional Chinese medicine.The detection method is prepared by reference solution, preparation of test solution, using ultra high performance liquid chromatography analysis, multiple batches of liquid chromatogram is introduced into "traditional Chinese medicine chromatographic fingerprint similarity evaluation system", 21 common peaks are identified, similarity matching is carried out with 21 common peaks, and the control spectrum of zhangtou red pericarpium citri reticulatae is generated.On this basis, combined with hesperidin, sweet orange flavone, chuan chenpisi, tangeretin, 5-dimethyl chuan chenpisi 5 flavonoid content determination, zhangtou red pericarpium citri reticulatae quantitative fingerprint is established.The application realizes that fingerprint detection and the content determination of 5 flavonoids of zhangtou red pericarpium citri reticulatae can be completed at the same time through one analysis, can quickly, comprehensively and accurately evaluate the quality of zhangtou red pericarpium citri reticulatae, has good reproducibility and stability, and can provide technical support for the uniformity and stability of zhangtou red pericarpium citri reticulatae quality.

The invention discloses a method for identifying Xinhui pericarpium citri reticulatae and pericarpium citri reticulatae, which is characterized in that four active ingredients including hesperidin, nobiletin, tangeretin and 2-methylamino methyl benzoate are simultaneously detected through high performance liquid chromatography, and distinguishing is realized according to detection data. The method comprises the following specific steps: preparing a mixed reference solution and a test solution, extracting a test with methanol, performing ultrasonic treatment, and filtering, specific chromatographic conditions are adopted for detection, the detection wavelength of the hesperidin is 283nm, and the detection wavelengths of the other three components are 330nm. Test results show that the contents of the four active ingredients in the Xinhui pericarpium citri reticulatae are high, the content of methyl 2-methylaminobenzoate is not lower than 0.020%, the ratio of the total amount of nobiletin and tangeretin to hesperidin is not lower than 0.17, and related indexes of the pericarpium citri reticulatae are remarkably low. The method is efficient, accurate, stable and reliable, and provides technical support for standardizing market circulation, guaranteeing product quality and promoting standardized development of the Xinhui pericarpium citri reticulatae industry.

The present invention discloses a method for constructing a fingerprint of Gualou Niu Bang decoction, relating to the technical field of analytical chemistry. The method is simple and has high precision, stability, and repeatability. Determination revealed that seven components, including geniposide, liquiritin, hesperidin, arctiin, baicalin, melaleucalyptol A-7-O-β-D-glucuronide, and wogonin, can be used as common characteristic peaks in the fingerprint of Gualou Niu Bang decoction for identification research.

The application discloses a suspension for improving DON-caused piglet intestinal toxicity and a preparation method and application thereof, and belongs to the technical field of feed additives, and comprises the following raw materials: hesperidin 40-60 mg / mL, sodium butyrate 50-150 mg / mL and PR-39 antibacterial peptide 10-15 mg / mL. The suspension provided by the application can also regulate intestinal flora balance, promote the proliferation of beneficial bacteria such as lactobacillus, and inhibit the growth of harmful bacteria. The effect of the suspension provided by the application is significantly better than that of single component or partial combination, and the suspension provides an efficient and safe nutritional intervention strategy for preventing and treating animal body damage caused by feed mycotoxin pollution.

The utility model provides a foreign matter detecting and removing device used before hesperidin finished product packaging, and belongs to the technical field of hesperidin processing. Comprising a conveying channel, materials are conveyed in the conveying channel through negative pressure suction, a foreign matter detector and a filtering assembly are arranged on the conveying channel, the filtering assembly comprises a filtering channel, a movable cylinder slides in the filtering channel, the movable cylinder comprises a partition plate and filtering cylinders coaxially and rotatably arranged on the two sides of the partition plate, and filtering pieces are arranged on the filtering cylinders; and a collecting assembly for collecting impurities filtered out by the filtering piece is arranged on the filtering channel. Impurities in hesperidin powder passing through the conveying channel can be filtered out through the filtering piece, when the foreign matter detector detects that the impurities pass through, the movable barrel is controlled to move in the filtering channel in a delayed mode, the other filtering barrel is moved into the conveying channel alternately, the filtering barrel with the impurities dumps and collects the impurities through rotation, and therefore the impurities can be filtered out through the filtering piece. The hesperidin powder filtering device has the effect of filtering hesperidin powder under the condition that equipment is not stopped.

The invention discloses a microbial fertilizer for treating citrus huanglongbing and a preparation method of the microbial fertilizer, and belongs to the field of agricultural biological control. 33 to 50 percent of sodium alginate-chitosan microspheres; 5 to 8% of hesperidin; 3-5% of nano zinc oxide; 2-4% of humic acid chelated boron; 2-4% of sucrose fatty acid ester; 2-4% of diatomite; wherein the preparation method of the sodium alginate-chitosan microspheres comprises the following steps: mixing sodium alginate with a microbial suspension, dropwise adding the mixture into a calcium chloride solution by using an injector, and standing and curing to form a microsphere core; and immersing the cured microspheres into a chitosan solution with the pH value of 6.0, taking out, and freeze-drying to obtain finished microspheres. Wherein the microbial suspension comprises trichoderma, bacillus and actinomycetes. The invention solves the problems of poor prevention and treatment effect of the existing Candidatus Liberobacter asiaticum, difficulty in colonization of the strain at phloem, short survival time and lack of targeted slow release function.

The utility model provides an operation table for hesperidin raw material pretreatment, and belongs to the technical field of hesperidin production. Comprising an operation table body, a cleaning tank is arranged on the operation table body, a liquid discharging pipe is arranged at the bottom of the cleaning tank, a valve is arranged on the liquid discharging pipe, a mounting frame is vertically and slidably arranged in the cleaning tank, a cleaning barrel used for containing hesperidin raw materials is rotatably arranged in the mounting frame, a feeding opening is formed in the outer wall of the cleaning barrel, and a cover plate is rotatably arranged at the feeding opening; a plurality of water inlet holes are formed in the outer wall of the cover plate and the outer wall of the cleaning barrel, a connecting piece is arranged between the cover plate and the cleaning barrel, a spreading and airing frame used for moving to the position below the cleaning barrel to receive hesperidin raw materials is horizontally and linearly arranged on the operation table body in a sliding mode, and a first driving piece used for driving the mounting frame to move is arranged on the operation table body. The second driving part is used for driving the airing rack to move, and a third driving part used for driving the cleaning barrel to rotate is arranged on the mounting frame. And the effect of reducing the labor intensity of workers is achieved.

Nutritional supplements and compositions for activating the GLP-1 peptide and / or other hormones in a subject in order to regulate blood sugar, weight, and hunger of the subject are described in this application. The compositions include a first nutritional supplement containing specific amounts of hydrolyzed Acacia gum, lemon bioflavonoids, chromium, Berberis aristate, and hesperidin. The compositions also include a second nutritional supplement containing specific amounts of flax seed oil, resistant potato starch, resistant tapioca fiber, kombucha, Bacillus coagulans, Bacillus clausii, and allulose. A third composition includes the first and second nutritional supplements containing these ingredients in sufficient amounts to regulate the GLP-1 peptide and / or other hormones. These compositions are able to increase the GLP-1 concentration in the blood by up to about 140% without binding directly to any GLP-1 receptors. Other embodiments are also described.

The utility model discloses an extraction tank for preparing methyl hesperidin. The extraction tank comprises an extraction tank, a fixed seat is arranged at the top of the extraction tank, a motor and a stirring shaft are arranged on the fixed seat, and one end of the stirring shaft penetrates through a bearing on the fixed seat and is connected with the motor; a paddle wheel and a stirring frame are arranged on the stirring shaft, the stirring frame is provided with lantern rings, transverse rods, vertical rods and stirring blades, the three lantern rings are sequentially arranged on the stirring shaft at intervals, each lantern ring is provided with two transverse rods which are symmetrically arranged, the two vertical rods are connected with the transverse rods on the two sides of the lantern ring respectively, and the stirring blades are fixed to the vertical rods. The paddle wheel at the tail end of the stirring shaft can push liquid to the bottom of the tank, the stirring blades facing the outer side on the vertical rods can stir the liquid outwards, the stirring blades facing the inner side on the vertical rods can stir the liquid outwards, the front end openings of the stirring blades are large, the rear end openings of the stirring blades are small, and the stirring effect is achieved through the flow velocity difference of the liquid at the two end openings. The liquid is stirred in multiple directions, so that the stirring efficiency is improved.

The invention discloses a preparation method of a hesperidin regulated polyamide nanofiltration membrane. The preparation method comprises the following steps: S1, contacting the surface of a base membrane with a water-phase solution, standing, and removing the water-phase solution; s2, the surface of the base membrane with the water phase solution removed in the step S1 makes contact with an organic phase solution, interfacial polymerization is carried out, and the hesperidin-regulated polyamide nanofiltration membrane is prepared; the aqueous phase solution contains hesperidin, an amine monomer and water; the mass volume ratio of the hesperidin to the water is (5-10): 1g / L, and the mass volume ratio of the amine monomer to the water is (4-6): 1g / L; the organic phase solution contains an acyl chloride monomer and an organic solvent; the mass volume ratio of the acyl chloride monomer to the organic solvent is (1.3-2): 1g / L. The polyamide nanofiltration membrane has excellent inorganic salt / antibiotic selectivity while keeping excellent water flux and antibiotic rejection rate, and can be applied to devices such as sewage treatment equipment, seawater desalination equipment, industrial wastewater treatment and recycling equipment and the like.

The invention discloses a preparation method of natural product co-assembled nanoparticles, and hesperidin and emodin are subjected to a co-assembly process to form carrier-free nanoparticles, so that the natural product co-assembled nanoparticles are obtained. The invention further provides the natural product co-assembled nanoparticles prepared by the preparation method and application of the natural product co-assembled nanoparticles. According to the natural product co-assembled nanoparticles provided by the invention, emodin which is rapidly released in an early stage can rapidly kill methicillin-resistant staphylococcus aureus (MRSA) on the surface of a wound, and a local antibacterial barrier is established; the hesperidin continuously released in the later stage plays an anti-inflammatory role by regulating and controlling the expression of inflammatory factors, and promotes the proliferation of fibroblasts and the secretion of angiogenesis-related growth factors (such as VEGF) at the same time. The'space-time synergistic release strategy 'provides a multifunctional platform integrating antibiosis, anti-inflammation and tissue repair for chronic wound treatment, and is suitable for accelerating healing of chronic wounds such as infection, diabetes and burn.

The invention discloses a lactobacillus mucosa mucus strain for producing various active small molecules by fermenting white truffle and cooperatively resisting skin cell aging at multiple targets, and belongs to the technical field of microorganisms. According to the lactobacillus mucosa mucosae CCFM1495 obtained through screening, cell proliferation can be carried out while the white truffle is fermented, and multiple active small molecule substances such as m-hydroxyphenylacetic acid, salicylic acid and hesperetin are generated. The fermentation liquor of the lactobacillus mucosa mucus CCFM1495 fermented white truffle can improve the skin quality through multi-target synergistic resistance to skin cell aging, and has a huge application prospect in preparation of products for improving the skin quality.

The utility model relates to the technical field of hesperidin extraction and production devices, and particularly discloses a centrifugal device for hesperidin crystallization and separation, which comprises a bearing component arranged in a centrifugal machine body; the lifting assembly is arranged on the cover plate and used for driving the bearing component to do lifting motion in the gravity direction so as to drive the bearing component to enter / exit from the centrifugal rotary drum; the sliding block is arranged on the bearing component in a sliding mode and can slide in the radial direction of the centrifugal rotating drum; the rotating roller is parallel to the central axis of the centrifugal rotating drum and is rotatably arranged on the sliding block; a main body of the telescopic part is fixedly installed on the bearing part, and a piston rod of the telescopic part is used for pushing the sliding block to face the inner wall face close to the centrifugal rotary drum so as to extrude the orange peel residues; by using the hesperidin residue separation device, the rotary roller can effectively extrude out the residual filtrate in the hesperidin residue, so that the waste amount of hesperidin is reduced, and the crystallization separation efficiency of hesperidin in the subsequent filtrate is improved.

The application provides a blood-activating and stasis-resolving external use plaster and a preparation process thereof, and the plaster is a microneedle-plaster composite preparation which is composed of a drug active ingredient, a sustained-release agent, a penetrating agent, an absorbent and a humectant. The drug active ingredient includes various Chinese herbal medicines such as Dysosma Versipellis, frankincense and myrrh, and the absorbent is a mixture of polyglutamic acid and snail polypeptide solution. The preparation process includes the steps of crushing medicinal materials, extracting with ethanol, concentrating and collecting cream, preparing a mixed solution, preparing a microneedle-plaster composite preparation and coating and the like. The snail polypeptide solution is obtained by enzymolysis of snail homogenate, and the humectant can be selected from hesperidin, glycerol and the like. The dissolvable material is selected from polylactic acid-hydroxyacetic acid copolymer and the like, and the ultrasonic power and frequency and the stirring speed of ultrasonic stirring all have certain ranges. The plaster has the effects of activating blood and resolving stasis and strengthening muscles and bones, and is suitable for external use. The preparation process is simple and feasible, and has high practical value and application prospect.

To provide an inhibitor of expression of a receptor for adherence of pneumonia-causing bacteria.SOLUTION: An inhibitor of expression of a receptor for adherence of pneumonia-causing bacteria comprises at least one selected from the group consisting of hesperidin, cinnamaldehyde, citric acid hydrate, L-glutamic acid hydrochloride, and tartaric acid.SELECTED DRAWING: None

This invention belongs to the field of pharmaceutical technology and relates to a preparation process of a modified Huoxiang Zhengqi compound. The preparation process is as follows: Pinellia ternata and Angelica dahurica are percolated; Pogostemon cablin, Perilla frutescens, Citrus reticulata peel, Magnolia officinalis, and Atractylodes macrocephala are extracted in groups for 2-5 hours, and the total volatile oil is collected. The residues of each group are decocted with water, and the decoctions of each group are collected; Poria cocos, Platycodon grandiflorus, Glycyrrhiza uralensis, Areca catechu peel, Ziziphus jujuba, and Zingiber officinale are decocted with water to obtain a decoction; the total volatile oil is added to an inclusion material, and inclusion is obtained using an ultrasonic-assisted method; the percolation and decoctions are combined, concentrated, and centrifuged to obtain a supernatant; a preservative is added to the supernatant and the inclusion material to obtain the final product. This invention extracts medicinal materials containing volatile oils in groups and uses a cyclodextrin inclusion complexation process, which not only improves the total extraction rate of volatile oils, but also increases the content of hesperidin, hydrated oxypenicillin, magnolol, honokiol, patchouli flavonol, and baicalein, while improving the taste and flavor of the flavored patchouli flavonoid compound.

The invention relates to the technical field of gene engineering, and discloses an application of a CsCSE2 gene in increasing the content of citrus vicenin-2 and / or hesperidin, the CDS sequence of the CsCSE2 gene is shown as SEQ ID NO.1, and the protein sequence coded by the CsCSE2 gene is shown as SEQ ID NO.2. The invention also discloses a method for preparing the CsCSE2 gene for improving the content of citrus vicenin-2 and / or hesperidin. According to the invention, the CsCSE2 gene is found to be positively correlated with the content of citrus vicenin-2 and / or hesperidin for the first time, and in an experiment, the highest value of citrus of which the CsCSE2 gene overexpression vector is transformed can be 69.38% higher than that of citrus of which an empty vector is transformed; therefore, the CsCSE2 gene can be used as a candidate gene for breeding a new citrus variety with high-dimensioning-2 and / or hesperidin content, and has important significance in breeding a new functional citrus variety by adopting a genetic engineering method, accelerating the breeding process, reducing the breeding workload and improving the comprehensive utilization rate of citrus.

The present application provides an herbal supplement and a method for relieving symptoms of gastroesophageal reflux disease (GERD). The herbal supplement includes two or more herbal ingredients selected from the group consisting of atractylodes lancea extract, dandelion root extract, noni extract, hesperidin extract, and lignum extract.

The application discloses a preparation method of a hesperidin-regulated polyamide nanofiltration membrane. The preparation method comprises the following steps: S1, contacting the surface of a base membrane with an aqueous solution, standing, and removing the aqueous solution; S2, contacting the surface of the base membrane after removing the aqueous solution in step S1 with an organic phase solution, and performing interfacial polymerization to obtain a hesperidin-regulated polyamide nanofiltration membrane; the aqueous solution contains hesperidin, an amine monomer and water; the mass-volume ratio of hesperidin and water is 5-10:1 g / L, and the mass-volume ratio of the amine monomer and water is 4-6:1 g / L; the organic phase solution contains an acid chloride monomer and an organic solvent; the mass-volume ratio of the acid chloride monomer and the organic solvent is 1.3-2:1 g / L. The polyamide nanofiltration membrane has excellent water flux and antibiotic retention rate, and also has excellent inorganic salt / antibiotic selectivity, and can be applied to sewage treatment equipment, seawater desalination equipment, industrial wastewater treatment and reuse equipment and the like.

The application discloses a kind of medicine food homologous sputum-removing and spleen-strengthening compositions and preparation method and application thereof, the composition includes: naringin 120-200 parts, hesperidin 80-100 parts, tuckahoe polysaccharide 150-250 parts, coix seed polysaccharide 80-120 parts, gingerol 10-20 parts, perillaldehyde 5-18 parts, glycyrrhizic acid 10-25 parts and glycyrrhizin flavone 8-24 parts by weight parts.The composition of the application can be prepared into medicine food homologous product, and it is not against disease, but against symptom, and has significant, stable and safe improvement effect on phlegm, throat discomfort, abdominal distension, thick and greasy tongue fur and other phlegm-related symptoms, without obvious toxic and side effects, and meets daily consumption requirements.

The application discloses application of a CsFLS1 gene in breeding of new citrus varieties, belongs to the technical field of genetic engineering, and particularly relates to application of the CsFLS1 gene in breeding of new citrus varieties, wherein the CDS sequence of the CsFLS1 gene is shown as SEQ ID NO. 1. The application proposes the application of the CsFLS1 gene in breeding of new citrus varieties, and through overexpression of the CsFLS1 gene, the content of hesperidin in citrus peel is improved, which indicates that the CsFLS1 gene can be used as a candidate gene related to synthesis of hesperidin, and contributes to the cultivation of functional new citrus varieties by using a genetic engineering method, accelerates a breeding process, and reduces a breeding workload.

The invention provides a low-browning carrot dietary fiber and an extraction method and application thereof.According to the method, accurate layered dissociation of carrot cell walls is achieved through the synergistic effect of low-temperature high-pressure pulse and targeted enzymolysis, and fiber skeletons are physically separated from browning substrates; meanwhile, natural bamboo fiber hollow nanotubes are adopted to load mulberry anthocyanin and hesperidin to form a composite color fixative, and enzymatic browning and non-enzymatic browning are inhibited respectively through a sequential controlled release mechanism. The whole process of the method is low in temperature and free of chemical addition, the problem of color deterioration in the extraction process is further solved, and high-value utilization of by-products is achieved.

The invention relates to the technical field of traditional Chinese medicine, in particular to a composition with a qi-blood tonifying effect and a pharmaceutical preparation and application thereof. The composition is prepared from the following raw materials in parts by weight: 0.2 to 1 part of tangeretin, 0.2 to 5 parts of nobiletin, 0.05 to 0.2 part of lobetyolin, 0.1 to 1 part of allantoin, 0.1 to 1 part of liquiritigenin, 0.1 to 1 part of alnus ketone, 0.02 to 0.2 part of rutin, 0.2 to 2 parts of apiose liquiritin and 0.1 to 1 part of ammonium glycyrrhizinate. The traditional Chinese medicine composition has the remarkable effects of replenishing blood and qi, treating anemia and resisting fatigue.

The invention discloses a traditional Chinese medicine composition for enhancing functions of mature skeletal muscle cells and application of the traditional Chinese medicine composition. The composition is prepared from ginseng, astragalus membranaceus, pericarpium citri reticulatae, dogwood and rhizoma polygonati according to a specific ratio. The invention also provides an establishment method based on the quality standard of various active components (ginsenoside Rg1, hesperidin and the like) in the composition. The traditional Chinese medicine composition disclosed by the invention does not have a remarkable activity promoting effect on undifferentiated C2C12 myoblasts in a proliferation period, but can specifically enhance the cell activity of differentiated mature C2C12 myotubular cells. The action characteristics of the cell state dependence show that the composition does not simply stimulate cell proliferation, but is targeted to improve the functional state of mature muscle cells, so that a high-precision solution is provided for treating diseases (such as sarcopenia) characterized by mature muscle fiber function decline.

The present invention belongs to the field of analysis of traditional Chinese medicine preparations, and specifically relates to a method for determining the contents of seven active ingredients in the classic ancient prescription Xiangsha Liujunzi Decoction. This method utilizes high-performance liquid chromatography (HPLC) under the same experimental conditions to simultaneously separate and determine the contents of liquiritin, apigenin, naringin, hesperidin, nobiletin, costunolide, and dehydrocostuslactone in Xiangsha Liujunzi Decoction. Experimental results demonstrate that the HPLC method established herein for simultaneously determining the contents of multiple different index components in a preparation is simple, rapid, accurate, reliable, and exhibits good repeatability and stability, making it suitable for use as a quality control method for the preparation.

The invention discloses pericarpium citri reticulatae fermentation liquor with an effect of improving intestinal health as well as a preparation method and application of the pericarpium citri reticulatae fermentation liquor, and belongs to the technical field of pericarpium citri reticulatae fermentation product processing. The dried orange peel fermentation liquor comprises a dried orange peel water extract and lactic acid bacteria strains, the lactic acid bacteria strains comprise any two or three of plant lactobacillus, lactobacillus paracasei and bifidobacterium longum, and the addition amount of the lactic acid bacteria strains is 0.02% of the mass of the dried orange peel water extract system. The hesperidin content and the antioxidant activity can be remarkably improved, the intestinal barrier function is enhanced, the process is simple and environmentally friendly, and wide application prospects and market potential are achieved.

The invention discloses a compound traditional Chinese medicine and application thereof in preparing a medicine for resisting eimeria tenella or treating coccidiosis, and relates to the technical field of livestock breeding. The compound traditional Chinese medicine comprises the following raw materials in parts by mass: 5-20 parts of hesperidin and 1-10 parts of citric acid. According to the invention, chicks are taken as experimental subjects, a chick coccidiosis model is established, and the effect of the compound traditional Chinese medicine on the chick coccidiosis is researched from the aspects of general conditions of the chicks, bloody stool conditions, coccidiocyst discharge conditions, cecum tissue lesion conditions, pathological detection, serum biochemistry, oxidation resistance detection and the like. The compound traditional Chinese medicine achieves a good anti-coccidiosis drug level, the required raw materials are low in cost, convenient to use and free of hormones and antibiotics, no toxic or side effect is caused to chickens, drug resistance cannot be caused, a new choice is provided for replacing chemical drugs for preventing and treating coccidiosis, and addition of anti-coccidiosis drugs in chicken feed is expected to be reduced or replaced.