56 results about "Hesperidin" patented technology

This invention discloses a quality control method for an anti-snoring oral liquid and its application, belonging to the field of traditional Chinese medicine quality testing technology. The method includes thin-layer chromatography identification of Gleditsia sinensis thorns, Scrophularia ningpoensis, and Glycyrrhiza uralensis, as well as high-performance liquid chromatography (HPLC) determination of hesperidin content. By optimizing pretreatment, developing solvent, and colorimetric conditions, this invention achieves efficient and specific identification and quantification of multiple components in the compound preparation. The method is highly specific, produces clear spots, has good separation, and is tolerant to a wide temperature and humidity range (2-40℃, 20%-75%RH), requiring no strict environmental control, significantly improving detection efficiency and providing a reliable basis for establishing quality standards for this preparation.

The invention discloses a method for identifying Xinhui pericarpium citri reticulatae and pericarpium citri reticulatae, which is characterized in that four active ingredients including hesperidin, nobiletin, tangeretin and 2-methylamino methyl benzoate are simultaneously detected through high performance liquid chromatography, and distinguishing is realized according to detection data. The method comprises the following specific steps: preparing a mixed reference solution and a test solution, extracting a test with methanol, performing ultrasonic treatment, and filtering, specific chromatographic conditions are adopted for detection, the detection wavelength of the hesperidin is 283nm, and the detection wavelengths of the other three components are 330nm. Test results show that the contents of the four active ingredients in the Xinhui pericarpium citri reticulatae are high, the content of methyl 2-methylaminobenzoate is not lower than 0.020%, the ratio of the total amount of nobiletin and tangeretin to hesperidin is not lower than 0.17, and related indexes of the pericarpium citri reticulatae are remarkably low. The method is efficient, accurate, stable and reliable, and provides technical support for standardizing market circulation, guaranteeing product quality and promoting standardized development of the Xinhui pericarpium citri reticulatae industry.

The application discloses a suspension for improving DON-caused piglet intestinal toxicity and a preparation method and application thereof, and belongs to the technical field of feed additives, and comprises the following raw materials: hesperidin 40-60 mg / mL, sodium butyrate 50-150 mg / mL and PR-39 antibacterial peptide 10-15 mg / mL. The suspension provided by the application can also regulate intestinal flora balance, promote the proliferation of beneficial bacteria such as lactobacillus, and inhibit the growth of harmful bacteria. The effect of the suspension provided by the application is significantly better than that of single component or partial combination, and the suspension provides an efficient and safe nutritional intervention strategy for preventing and treating animal body damage caused by feed mycotoxin pollution.

The utility model provides a foreign matter detecting and removing device used before hesperidin finished product packaging, and belongs to the technical field of hesperidin processing. Comprising a conveying channel, materials are conveyed in the conveying channel through negative pressure suction, a foreign matter detector and a filtering assembly are arranged on the conveying channel, the filtering assembly comprises a filtering channel, a movable cylinder slides in the filtering channel, the movable cylinder comprises a partition plate and filtering cylinders coaxially and rotatably arranged on the two sides of the partition plate, and filtering pieces are arranged on the filtering cylinders; and a collecting assembly for collecting impurities filtered out by the filtering piece is arranged on the filtering channel. Impurities in hesperidin powder passing through the conveying channel can be filtered out through the filtering piece, when the foreign matter detector detects that the impurities pass through, the movable barrel is controlled to move in the filtering channel in a delayed mode, the other filtering barrel is moved into the conveying channel alternately, the filtering barrel with the impurities dumps and collects the impurities through rotation, and therefore the impurities can be filtered out through the filtering piece. The hesperidin powder filtering device has the effect of filtering hesperidin powder under the condition that equipment is not stopped.

The utility model provides an operation table for hesperidin raw material pretreatment, and belongs to the technical field of hesperidin production. Comprising an operation table body, a cleaning tank is arranged on the operation table body, a liquid discharging pipe is arranged at the bottom of the cleaning tank, a valve is arranged on the liquid discharging pipe, a mounting frame is vertically and slidably arranged in the cleaning tank, a cleaning barrel used for containing hesperidin raw materials is rotatably arranged in the mounting frame, a feeding opening is formed in the outer wall of the cleaning barrel, and a cover plate is rotatably arranged at the feeding opening; a plurality of water inlet holes are formed in the outer wall of the cover plate and the outer wall of the cleaning barrel, a connecting piece is arranged between the cover plate and the cleaning barrel, a spreading and airing frame used for moving to the position below the cleaning barrel to receive hesperidin raw materials is horizontally and linearly arranged on the operation table body in a sliding mode, and a first driving piece used for driving the mounting frame to move is arranged on the operation table body. The second driving part is used for driving the airing rack to move, and a third driving part used for driving the cleaning barrel to rotate is arranged on the mounting frame. And the effect of reducing the labor intensity of workers is achieved.

Nutritional supplements and compositions for activating the GLP-1 peptide and / or other hormones in a subject in order to regulate blood sugar, weight, and hunger of the subject are described in this application. The compositions include a first nutritional supplement containing specific amounts of hydrolyzed Acacia gum, lemon bioflavonoids, chromium, Berberis aristate, and hesperidin. The compositions also include a second nutritional supplement containing specific amounts of flax seed oil, resistant potato starch, resistant tapioca fiber, kombucha, Bacillus coagulans, Bacillus clausii, and allulose. A third composition includes the first and second nutritional supplements containing these ingredients in sufficient amounts to regulate the GLP-1 peptide and / or other hormones. These compositions are able to increase the GLP-1 concentration in the blood by up to about 140% without binding directly to any GLP-1 receptors. Other embodiments are also described.

The invention discloses a lactobacillus mucosa mucus strain for producing various active small molecules by fermenting white truffle and cooperatively resisting skin cell aging at multiple targets, and belongs to the technical field of microorganisms. According to the lactobacillus mucosa mucosae CCFM1495 obtained through screening, cell proliferation can be carried out while the white truffle is fermented, and multiple active small molecule substances such as m-hydroxyphenylacetic acid, salicylic acid and hesperetin are generated. The fermentation liquor of the lactobacillus mucosa mucus CCFM1495 fermented white truffle can improve the skin quality through multi-target synergistic resistance to skin cell aging, and has a huge application prospect in preparation of products for improving the skin quality.

The utility model relates to the technical field of hesperidin extraction and production devices, and particularly discloses a centrifugal device for hesperidin crystallization and separation, which comprises a bearing component arranged in a centrifugal machine body; the lifting assembly is arranged on the cover plate and used for driving the bearing component to do lifting motion in the gravity direction so as to drive the bearing component to enter / exit from the centrifugal rotary drum; the sliding block is arranged on the bearing component in a sliding mode and can slide in the radial direction of the centrifugal rotating drum; the rotating roller is parallel to the central axis of the centrifugal rotating drum and is rotatably arranged on the sliding block; a main body of the telescopic part is fixedly installed on the bearing part, and a piston rod of the telescopic part is used for pushing the sliding block to face the inner wall face close to the centrifugal rotary drum so as to extrude the orange peel residues; by using the hesperidin residue separation device, the rotary roller can effectively extrude out the residual filtrate in the hesperidin residue, so that the waste amount of hesperidin is reduced, and the crystallization separation efficiency of hesperidin in the subsequent filtrate is improved.

This invention belongs to the field of pharmaceutical technology and relates to a preparation process of a modified Huoxiang Zhengqi compound. The preparation process is as follows: Pinellia ternata and Angelica dahurica are percolated; Pogostemon cablin, Perilla frutescens, Citrus reticulata peel, Magnolia officinalis, and Atractylodes macrocephala are extracted in groups for 2-5 hours, and the total volatile oil is collected. The residues of each group are decocted with water, and the decoctions of each group are collected; Poria cocos, Platycodon grandiflorus, Glycyrrhiza uralensis, Areca catechu peel, Ziziphus jujuba, and Zingiber officinale are decocted with water to obtain a decoction; the total volatile oil is added to an inclusion material, and inclusion is obtained using an ultrasonic-assisted method; the percolation and decoctions are combined, concentrated, and centrifuged to obtain a supernatant; a preservative is added to the supernatant and the inclusion material to obtain the final product. This invention extracts medicinal materials containing volatile oils in groups and uses a cyclodextrin inclusion complexation process, which not only improves the total extraction rate of volatile oils, but also increases the content of hesperidin, hydrated oxypenicillin, magnolol, honokiol, patchouli flavonol, and baicalein, while improving the taste and flavor of the flavored patchouli flavonoid compound.

The invention relates to the technical field of gene engineering, and discloses an application of a CsCSE2 gene in increasing the content of citrus vicenin-2 and / or hesperidin, the CDS sequence of the CsCSE2 gene is shown as SEQ ID NO.1, and the protein sequence coded by the CsCSE2 gene is shown as SEQ ID NO.2. The invention also discloses a method for preparing the CsCSE2 gene for improving the content of citrus vicenin-2 and / or hesperidin. According to the invention, the CsCSE2 gene is found to be positively correlated with the content of citrus vicenin-2 and / or hesperidin for the first time, and in an experiment, the highest value of citrus of which the CsCSE2 gene overexpression vector is transformed can be 69.38% higher than that of citrus of which an empty vector is transformed; therefore, the CsCSE2 gene can be used as a candidate gene for breeding a new citrus variety with high-dimensioning-2 and / or hesperidin content, and has important significance in breeding a new functional citrus variety by adopting a genetic engineering method, accelerating the breeding process, reducing the breeding workload and improving the comprehensive utilization rate of citrus.

The present application provides an herbal supplement and a method for relieving symptoms of gastroesophageal reflux disease (GERD). The herbal supplement includes two or more herbal ingredients selected from the group consisting of atractylodes lancea extract, dandelion root extract, noni extract, hesperidin extract, and lignum extract.

The application discloses a preparation method of a hesperidin-regulated polyamide nanofiltration membrane. The preparation method comprises the following steps: S1, contacting the surface of a base membrane with an aqueous solution, standing, and removing the aqueous solution; S2, contacting the surface of the base membrane after removing the aqueous solution in step S1 with an organic phase solution, and performing interfacial polymerization to obtain a hesperidin-regulated polyamide nanofiltration membrane; the aqueous solution contains hesperidin, an amine monomer and water; the mass-volume ratio of hesperidin and water is 5-10:1 g / L, and the mass-volume ratio of the amine monomer and water is 4-6:1 g / L; the organic phase solution contains an acid chloride monomer and an organic solvent; the mass-volume ratio of the acid chloride monomer and the organic solvent is 1.3-2:1 g / L. The polyamide nanofiltration membrane has excellent water flux and antibiotic retention rate, and also has excellent inorganic salt / antibiotic selectivity, and can be applied to sewage treatment equipment, seawater desalination equipment, industrial wastewater treatment and reuse equipment and the like.

The application discloses a kind of medicine food homologous sputum-removing and spleen-strengthening compositions and preparation method and application thereof, the composition includes: naringin 120-200 parts, hesperidin 80-100 parts, tuckahoe polysaccharide 150-250 parts, coix seed polysaccharide 80-120 parts, gingerol 10-20 parts, perillaldehyde 5-18 parts, glycyrrhizic acid 10-25 parts and glycyrrhizin flavone 8-24 parts by weight parts.The composition of the application can be prepared into medicine food homologous product, and it is not against disease, but against symptom, and has significant, stable and safe improvement effect on phlegm, throat discomfort, abdominal distension, thick and greasy tongue fur and other phlegm-related symptoms, without obvious toxic and side effects, and meets daily consumption requirements.

The application discloses application of a CsFLS1 gene in breeding of new citrus varieties, belongs to the technical field of genetic engineering, and particularly relates to application of the CsFLS1 gene in breeding of new citrus varieties, wherein the CDS sequence of the CsFLS1 gene is shown as SEQ ID NO. 1. The application proposes the application of the CsFLS1 gene in breeding of new citrus varieties, and through overexpression of the CsFLS1 gene, the content of hesperidin in citrus peel is improved, which indicates that the CsFLS1 gene can be used as a candidate gene related to synthesis of hesperidin, and contributes to the cultivation of functional new citrus varieties by using a genetic engineering method, accelerates a breeding process, and reduces a breeding workload.

The invention provides a low-browning carrot dietary fiber and an extraction method and application thereof.According to the method, accurate layered dissociation of carrot cell walls is achieved through the synergistic effect of low-temperature high-pressure pulse and targeted enzymolysis, and fiber skeletons are physically separated from browning substrates; meanwhile, natural bamboo fiber hollow nanotubes are adopted to load mulberry anthocyanin and hesperidin to form a composite color fixative, and enzymatic browning and non-enzymatic browning are inhibited respectively through a sequential controlled release mechanism. The whole process of the method is low in temperature and free of chemical addition, the problem of color deterioration in the extraction process is further solved, and high-value utilization of by-products is achieved.

The invention relates to the technical field of traditional Chinese medicine, in particular to a composition with a qi-blood tonifying effect and a pharmaceutical preparation and application thereof. The composition is prepared from the following raw materials in parts by weight: 0.2 to 1 part of tangeretin, 0.2 to 5 parts of nobiletin, 0.05 to 0.2 part of lobetyolin, 0.1 to 1 part of allantoin, 0.1 to 1 part of liquiritigenin, 0.1 to 1 part of alnus ketone, 0.02 to 0.2 part of rutin, 0.2 to 2 parts of apiose liquiritin and 0.1 to 1 part of ammonium glycyrrhizinate. The traditional Chinese medicine composition has the remarkable effects of replenishing blood and qi, treating anemia and resisting fatigue.

The invention discloses a traditional Chinese medicine composition for enhancing functions of mature skeletal muscle cells and application of the traditional Chinese medicine composition. The composition is prepared from ginseng, astragalus membranaceus, pericarpium citri reticulatae, dogwood and rhizoma polygonati according to a specific ratio. The invention also provides an establishment method based on the quality standard of various active components (ginsenoside Rg1, hesperidin and the like) in the composition. The traditional Chinese medicine composition disclosed by the invention does not have a remarkable activity promoting effect on undifferentiated C2C12 myoblasts in a proliferation period, but can specifically enhance the cell activity of differentiated mature C2C12 myotubular cells. The action characteristics of the cell state dependence show that the composition does not simply stimulate cell proliferation, but is targeted to improve the functional state of mature muscle cells, so that a high-precision solution is provided for treating diseases (such as sarcopenia) characterized by mature muscle fiber function decline.

The invention discloses a compound traditional Chinese medicine and application thereof in preparing a medicine for resisting eimeria tenella or treating coccidiosis, and relates to the technical field of livestock breeding. The compound traditional Chinese medicine comprises the following raw materials in parts by mass: 5-20 parts of hesperidin and 1-10 parts of citric acid. According to the invention, chicks are taken as experimental subjects, a chick coccidiosis model is established, and the effect of the compound traditional Chinese medicine on the chick coccidiosis is researched from the aspects of general conditions of the chicks, bloody stool conditions, coccidiocyst discharge conditions, cecum tissue lesion conditions, pathological detection, serum biochemistry, oxidation resistance detection and the like. The compound traditional Chinese medicine achieves a good anti-coccidiosis drug level, the required raw materials are low in cost, convenient to use and free of hormones and antibiotics, no toxic or side effect is caused to chickens, drug resistance cannot be caused, a new choice is provided for replacing chemical drugs for preventing and treating coccidiosis, and addition of anti-coccidiosis drugs in chicken feed is expected to be reduced or replaced.

The invention discloses an HPLC specific chromatogram and component content detection method of a radix astragali-lepidii heart-strengthening capsule, and belongs to the technical field of quality control of traditional Chinese medicines. The establishment method of the HPLC characteristic chromatogram of the radix astragali-lepidium meyenii heart-strengthening capsule comprises the following steps: preparing a test solution from the content of the radix astragali-lepidium meyenii heart-strengthening capsule; the preparation method comprises the following steps: respectively weighing adenosine, guanosine, tanshinol, protocatechuic acid, protocatechuic aldehyde, catechin, 4-methoxysalicylaldehyde, calycosin glucoside, narirutin, hesperidin, rosmarinic acid, alkannic acid, salvianolic acid B, apigenin and formononetin, and preparing a mixed reference solution; and carrying out HPLC detection analysis on the test solution and the mixed reference substance solution to obtain the HPLC characteristic chromatogram of the astragalus membranaceus-lepidium monnieri heart-strengthening capsule. The method has the advantages of strong specificity, high precision, good stability and good repeatability, can realize characteristic spectrum identification and multi-component content control of the astragalus membranaceus-lepidium monnieri heart-strengthening capsule at the same time, and provides a reliable basis for production quality supervision and clinical medication safety of the astragalus membranaceus-lepidium monnieri heart-strengthening capsule.

The invention relates to a preparation method of a plant extract preservative for low-sugar food, which solves the problem of low-sugar food preservation by compounding lychee seeds and dried orange peel and combining an enzymolysis-ultrahigh pressure synergistic extraction process. Litchi nucleoside in the lychee seeds has a bacteriostatic effect, and hesperidin and limonene in the pericarpium citri reticulatae have antioxidant and color-protecting functions. Active components are released through enzymolysis pretreatment, the biological activity is reserved at low temperature through ultrahigh-pressure extraction, and high efficiency and stability are ensured. The preservative effectively inhibits putrefying bacteria in the low-sugar fruit and vegetable juice, delays browning, keeps the original flavor of the fruit and vegetable juice, and is free of peculiar smell and flavor interference. According to the method, agricultural wastes and by-products are utilized, the cost is reduced, the green production requirement is met, and good economical efficiency and environmental friendliness are achieved.

This invention discloses the application of a flavonoid compound from Citrus aurantium, specifically the application of a flavonoid compound from Citrus aurantium or its physiologically acceptable salt in the preparation of anti-inflammatory and / or therapeutic drugs for diseases related to lactate dehydrogenase release. The flavonoid compound from Citrus aurantium has the structural formula shown in Formula I, wherein R1 is selected from methoxy, hydrogen, ethoxy, or hydroxy; R2 is selected from methoxy, hydrogen, ethoxy, or hydroxy; R3 is selected from methoxy, hydrogen, ethoxy, or hydroxy; R4 is selected from methoxy, hydrogen, ethoxy, or hydroxy; R5 is selected from methoxy, hydrogen, ethoxy, or hydroxy; R6 is selected from methoxy, hydrogen, ethoxy, or hydroxy; and the C2-C3 bond is a double bond or a saturated bond. This invention clarifies that among the flavonoid compounds from Citrus aurantium, isopyroside, apigenin, norihesperidin, hesperidin, and isohesperidin can significantly inhibit LPS-induced LDH release in HL-1 cells and can serve as lead compounds for antiseptic myocardial injury drugs.

This invention discloses a formula and process for Naoluotong capsules, relating to the field of Naoluotong capsule production technology. To improve the quality of medicinal material processing during production, the equipment includes a processing tank with a lifting chamber at the top and a feeding hopper on one outer wall. A stirring mechanism is installed inside the tank, comprising a stirring main shaft and a stirring rod. A stirring motor is fixed to one outer wall of the tank, the stirring main shaft is rotatably connected to the output end of the stirring motor, and the stirring rod is uniformly fixed to the circumferential outer wall of the stirring main shaft. The formula includes the following components: 10% Ligusticum chuanxiong extract, 10% Salvia miltiorrhiza extract, 10% Astragalus membranaceus extract, 10% tolperidone hydrochloride, 2% methyl hesperidin, and 0.4% vitamin B6. By incorporating a stirring motor, a stirring rod, and an extension rod, this invention enables the stirring motor to drive the stirring rod and extension rod to rotate, thereby agitating the medicinal materials inside the processing tank and improving the cleaning effect.

The invention belongs to the technical field of feeds, and particularly relates to a special feed for low-cholesterol eggs and a preparation process of the special feed. The invention discloses a composition. The composition is prepared from the following components: plant polysaccharide, plant polypeptide, hesperidin, lactobionic acid, cordycepin and pubescent holly root saponin. The invention also discloses an application of the composition in preparation of a special feed for low-cholesterol eggs. A certain amount of the composition is added into the basal feed, the composition takes plant polysaccharide and plant polypeptide as main raw materials and takes hesperidin, lactobionic acid and other active molecules as auxiliary materials, and the combination of the components has a synergistic effect, so that the immunity and disease resistance of laying hens can be effectively improved, the laying rate is ensured, and the quality of laying hens is improved. Meanwhile, the content of cholesterol in eggs can be reduced, the color of the eggs is improved, the viscosity of egg white and the strength of eggshells are improved, the breakage rate is reduced, and the comprehensive quality of the eggs is comprehensively improved.

The invention belongs to the technical field of plant component extraction processes, and particularly relates to a eutectic solvent-polymer aqueous two-phase system for high-yield co-extraction and high-selectivity separation of citrus flavone. The invention provides DES for extracting citrus flavone with high extraction rate. The DES consists of benzyltrimethylammonium chloride and xylitol, the invention also provides a eutectic solvent-polymer aqueous two-phase system for high-selectivity separation of citrus flavone, and the system is composed of a polymer, water and the DES. The DES is high in extraction yield of citrus peel flavones, and the highest extraction rate of total flavones can reach 16.784 mg / g; the partition coefficient of the eutecticevaporate solvent-polymer aqueous two-phase system for hesperidin can reach 14.34, the extraction rate can reach 93.48%, the partition coefficient of nobiletin can reach 2.23, the extraction rate can reach 99.05%, and the selectivity coefficient of the eutecticevaporate solvent-polymer aqueous two-phase system for hesperidin and nobiletin can reach 732.76.

The invention relates to the technical field of antibiosis and deodorization, in particular to a nano antibiosis and deodorization product extracted from Chinese herbal medicine and containing glucan for pets. The invention relates to a nano antibacterial and deodorant product extracted from Chinese herbal medicines and containing glucan for pets. The feed additive is prepared by mixing the following raw materials in parts by weight: 58 to 89 parts of purified water, 36 to 59 parts of lubrajel oil, 22 to 46 parts of hesperidin, 24 to 35 parts of allicin, 43 to 55 parts of synthetic houttuyfonate, 32 to 40 parts of gallic acid, 28 to 40 parts of trihydroxy-1-cycloethylene carboxylic acid, 30 to 47 parts of oat beta glucan, 25 to 30 parts of a dandelion chinensis extracting solution, 45 to 72 parts of a folium artemisiae argyi extracting solution, 14 to 35 parts of a cortex dictamni extracting solution, 22 to 45 parts of a portulaca grandiflora extracting solution and 50 to 68 parts of muraplase. The antibacterial deodorant product has the beneficial effects that the Chinese herbal medicines are extracted, the antibacterial deodorant product has no irritation to skin and hair, and the antibacterial deodorant product is used for resisting bacteria, killing mites and removing peculiar smell of pets and has important significance on health of the pets.

The invention discloses a method for detecting traditional Chinese medicine granules, which comprises the following step of: carrying out qualitative identification and / or content determination on exocarpium citri rubrum in the traditional Chinese medicine granules by adopting high performance liquid chromatography, taking octadecylsilane chemically bonded silica as a filling agent and taking hesperidin as an index component. The method is used for carrying out qualitative identification and content determination on exocarpium citri rubrum in the traditional Chinese medicine granules by taking hesperidin as an index component, and is a detection method for the traditional Chinese medicine granules, which is strong in specificity, high in accuracy and good in reproducibility.

The invention discloses a detection method for simultaneously determining the content of multiple components in a lip and tooth stomach clearing pill, and belongs to the technical field of quality control of traditional Chinese medicine compound preparations. According to the detection method, the six components including gentiopicroside, geniposide, berberine hydrochloride, hesperidin, baicalin and chrysophanol can be simultaneously determined through an HPLC wavelength switching method; the method gives consideration to the index components of monarch drugs, ministerial drugs and adjuvant drugs in the lip and tooth stomach clearing pills, has the advantages of simplicity and convenience in operation, high specificity, high accuracy and good repeatability and tolerance, and has positive significance in quality control and comprehensive evaluation of the lip and tooth stomach clearing pills.

The invention discloses a directional transformation method and application of a flavonoids compound of pericarpium citri reticulatae, and the directional transformation method of the flavonoids compound of pericarpium citri reticulatae comprises the following steps: inoculating bacillus velezensis into a fermentation system containing the flavonoids compound of pericarpium citri reticulatae, and fermenting to obtain the transformed flavonoids compound, the tangerine peel flavonoid compound comprises at least one of hesperidin, nobiletin and tangeretin. By screening an exclusive bacillus velezensis strain and an established oriented biotransformation system, the core technical bottlenecks of heavy pollution and severe conditions of a traditional chemical method and poor substrate specificity, low transformation efficiency and the like of a conventional microbiological method are fundamentally overcome, and efficient, green and oriented transformation of hesperidin, nobiletin and tangeretin is realized; the method is successfully applied to a solid-state fermentation process of the Xinhui pericarpium citri reticulatae, the content of high-activity flavone components is remarkably increased, and an innovative solution with remarkable industrial advantages is provided for high-value development of traditional Chinese medicinal materials.

The invention relates to a dietary supplement that contains: a) cranberry extract powder (Vaccinium oxycoccos and Vaccinium macrocarpon or cranberry), b) b-1) cranberry juice and / or b-2) cranberry juice powder, c) neohesperidin dihydrochalcone and possibly additional sweetener, d) a dietary supplement carrier preferably fructo- oligosaccharide syrup, and e) one or more other excipients.

The invention belongs to the field of traditional Chinese medicine quality control and detection methods, and particularly relates to a liver-transforming decoction characteristic chromatogram, a construction method and application thereof. According to the method, high performance liquid chromatography is adopted for detection, the construction of the HPLC characteristic chromatogram of the liver-removing decoction and the content determination of four components including geniposide, paeoniflorin, hesperidin and paeonol in a sample of the liver-removing decoction can be realized under a chromatographic condition, the detection period is shortened, the analysis efficiency is improved, and methodology verifies that the method has the advantages that the method is simple and convenient to operate, and the method is suitable for large-scale popularization and application. The method has good system adaptability, specificity, precision, stability, repeatability and the like, can realize qualitative and quantitative dual technical effects, and can effectively carry out comprehensive quality control and research on the liver-transforming decoction preparation.