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42 results about "Suppository" patented technology

A suppository is a solid dosage form that is inserted into the rectum (rectal suppository), vagina (vaginal suppository), or urethra (urethral suppository), where it dissolves or melts and exerts local or systemic effects. Suppositories are used to deliver medications that act both systemically and locally.

Disposable hemorrhoid treatment suppository

The utility model provides a disposable haemorrhoids treatment suppository, which comprises a treatment suppository body, the treatment suppository body comprises a suppository head, corrugated bulges, a cap, a capacity bin, a suppository tail, external threads and helical teeth, the surface of the suppository head is provided with a plurality of corrugated bulges, and a space is arranged between every two adjacent corrugated bulges. A bolt tail is integrally formed at the top of the bolt head, an opening is formed in the end of the bolt tail, a cover cap is arranged on the surface of the bolt tail in a sleeving mode, and oblique teeth are integrally formed on the side edge of the bolt tail. According to the haemorrhoids treatment suppository, the sealing effect on the suppository tail part is achieved through the additionally arranged cap structure, the cap can only be tightened but cannot be unscrewed, it is ensured that the problem of loosening after sealing is completed cannot occur, and the probability of liquid leakage is reduced. A plurality of corrugated bulge structures are additionally arranged on the suppository head part, and the contact surface with the large intestine can be effectively increased through the corrugated bulges, so that the overall treatment effect is better.
Owner:WUHAN XINJIAHAO MEDICAL INSTR CO LTD

Intravascular antithrombotic magnetic control device

ActiveCN224024021UStentsSurgeryInvasive treatmentsSuppository
The utility model relates to an intravascular antithrombotic magnetic control device which comprises an intravascular device and an external magnetic control device, the intravascular device comprises a medicine carrying assembly, a conveying catheter and a release control module, and the medicine carrying assembly and the release control module are respectively arranged in the conveying catheter; the external magnetic control device is used for fixing one end of the conveying catheter and is in communication connection with the release control module. The utility model has the benefits that the structure is simple, the design is reasonable, the release of suppository particles is accurately controlled through an external magnetic field, the minimally invasive treatment of a patient is realized, and safety and reliability are realized.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Anal medicine application auxiliary equipment

ActiveCN223439013UMedical devicesSuppositoryChange medication
The utility model discloses an anus-accommodating medicine-applying auxiliary device which comprises a medicine applying device, a medicine storage shell and a medicine applying mechanism. An extension table is arranged at the top of the dosing device; a movable cavity is further formed in the dosing device, and a through hole is vertically formed in the movable cavity; the medicine storage shell is connected into the movable cavity in a sliding mode, and a plurality of medicine storage cavities matched with the through holes and the extending tables are formed in the medicine storage shell. The medicine feeding mechanism comprises a partition plate, a medicine squeezing end and a spring strip. The partition plate is arranged at the bottom of the inner cavity of the medicine feeding device, and the spring strip is arranged between the medicine squeezing end and the partition plate. The anorectal suppository dosing device has the advantages that the technical problem that in the prior art, only one suppository can be added every time, when anorectal nurses need to change medicine for a plurality of patients, the anorectal nurses often have no time to add the suppository into the dosing device, and the working efficiency of the anorectal nurses is invisibly reduced is solved.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Integrated nursing device for eliminating thrombus in PICC (Peripherally Inserted Central Catheter) by ultrasonic waves

The invention relates to an integrated nursing device for eliminating thrombus in a PICC (Peripherally Inserted Central Catheter) by ultrasonic waves, which belongs to the technical field of medical instruments and comprises a handheld host and a disposable treatment head. A venturi negative pressure generating unit and a flushing fluid power unit are integrated in the handheld host. The disposable treatment head comprises a multi-section flexible connection structure capable of self-adapting to bending of the catheter, a miniature ultrasonic suppository breaking unit capable of achieving cross interference focusing based on a single crystal wafer and a reflection cavity, and a multi-layer coaxial cavity structure capable of achieving synchronous suction and flushing. When the device works, ultrasonic energy directly acts on thrombus in a catheter to efficiently crush the thrombus, meanwhile, fragments are removed in time through negative pressure generated by the Venturi effect, and visual state indication is provided through the mechanical feedback unit. The problems that a traditional method is low in efficiency, complex in operation and asynchronous in fragment removal are solved, and safe, efficient and convenient integrated catheter thrombus removal is achieved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

LED optical therapeutic apparatus for treating vaginitis

The application provides an LED optical therapeutic instrument for treating vaginitis, and relates to the technical field of optical therapeutic instruments, which comprises a moving cylinder, a battery box is fixed to the tail end of the moving cylinder, and the front end of the moving cylinder is provided with an opening, a pushing assembly is arranged in the moving cylinder, the pushing assembly comprises a front pipe, an intermediate pipe is arranged at the rear end of the front pipe, a rotating shaft is arranged between the front pipe and the intermediate pipe, a connecting layer is fixed to the tail end of the moving cylinder, a second screw rod is screw-connected in the connecting layer in a threaded manner, one end of the second screw rod is rotationally connected with the intermediate pipe through a bearing, and a mounting assembly is arranged at the bottom of the outlet end of the moving cylinder, through the unfolding of the inner supporting plate, the position of the disease is observed conveniently, the front pipe provided with a medicinal suppository is moved to the position through the pushing assembly, the medicinal suppository is applied to the position to be treated through the rotation of the rotating shaft, the position deviation is avoided, the sterilization and disinfection are concentrated through the irradiation of the irradiation lamp, and the treatment effect is improved.
Owner:JINGMEN MATERNAL & CHILD HEALTH HOSPITAL

Female filling adsorption suppository with telescopic function

ActiveCN224070950UMedical devicesSuppositoryStructural engineering
The utility model belongs to the technical field of gynecology medical instruments, and provides a woman packing adsorption suppository with a telescopic function, which comprises a pushing unit and a packing unit, the pushing unit comprises a pushing tube, the other end of the pushing tube is provided with a movable opening, and the packing unit is arranged in the movable opening. The other end of the pushing pipe is movably connected with a pushing rod through a movable opening, one end of the pushing rod is fixedly connected with a pushing plate, and a through opening is formed in one end of the pushing plate in a penetrating mode. The filling unit comprises an adsorption bolt body movably connected to the interior of the pushing pipe, an adjusting bolt is fixedly connected to one end of the adsorption bolt body, a limiting bolt is fixedly connected to one end of the adjusting bolt, a telescopic adsorption bolt is movably connected to the outer side of the adjusting bolt, and a sliding sleeve is fixedly connected to one end of the telescopic adsorption bolt; when a person walks and moves and slides down, the woman filling adsorption plug can be located at the optimal adsorption position, and therefore the adsorption effect of the woman filling adsorption plug is guaranteed.
Owner:YUNNAN SHUYUN TECH

Thread bolt for brain embolism experiment

ActiveCN223513595UEducational modelsCerebral embolusSuppository
The utility model relates to the technical field of cerebral embolism models, in particular to a suppository for cerebral embolism experiments, which comprises a catheter. The two sets of steering mechanisms are movably installed in the guide pipe and used for adjusting the orientation of the end of the guide pipe. The moving structure is movably mounted in the middle of the interior of the catheter, and the moving structure is used for blocking a blood vessel with the embolism; and the injection molding assembly is movably mounted at the upper end of the outer wall of the catheter and is used for filling the embolism. The utility model discloses. A corrugated pipe is installed on the lower side of the outer wall of the fixing block, so that the fixing block has certain rotating capacity, rotation is controlled through a first connecting line and a second connecting line which are fixedly connected to the lower side of the outer wall of the fixing block, two caps connected to the outer wall of the fixing block in a sleeving mode are matched with each other, and a user can manufacture blockages by means of wax blocks by himself / herself, so that the use cost is reduced; and through the cooperation of the guide pipe and the push rod, the wire bolt can be quickly moved to a target position to release the blocking object.
Owner:THE 7TH PEOPLES HOSPITAL OF ZHENGZHOU

Packaging box (Duozheta suppository)

ActiveCN309941715SSuppositoryDrug packaging
1. Name of the product in this design: Packaging Box (Double-Zolpidem Suppository). 2. Intended use of this design: for pharmaceutical packaging. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key features: the front view.
Owner:HUBEI HUMANWELL CHENGTIAN PHARMA

Protective silica gel sleeve for use of kaisai lu

ActiveCN224441902USuppositorySilica gel
This utility model discloses a protective silicone sleeve adapted for use with glycerin suppositories, comprising a spindle-shaped silicone body. The tail end of the silicone body has an insertion channel extending along its axis towards the head end, for inserting the head end of the suppository. The head end of the silicone body has a through-hole communicating with the insertion channel. An elastic antibacterial sleeve is fitted onto the outer wall of the silicone body near the tail end. The elastic antibacterial sleeve is formed by continuously rolling from the first end to the second end through an elastic tubular sheath, creating a ring-shaped self-rolling state. In its flattened state, the elastic antibacterial sleeve is longer than the silicone body. The silicone body is nestled into the front end of the opened suppository for alternative contact. After administration, the silicone body is removed, and the elastic antibacterial sleeve is flattened towards the front end to wrap around the silicone body. This significantly reduces the possibility of anal injury, greatly improves the patient's sense of security and comfort during treatment, and effectively shields and isolates the silicone body from contaminants after use.
Owner:NINGBO MEDICAL CENT LIHUILI HOSPITACL

System and method for lubricant delivery

PendingUS20260048007A1Suppositories deliveryMedical devicesSuppositorySurgery
Disclosed are suppositories and methods of use thereof for lubricating an internal surface of a body cavity. A suppository may be composed of a shell defining an internal volume and a lubricant at least partially occupying the internal volume. The shell may be prone to degrade in that a rate of degradation thereof may increase when the suppository is in a certain condition, such as being exposed to an external environment or being positioned inside the body cavity. Once sufficient degradation of the shell has occurred while the suppository is inside the body cavity, the lubricant may be released and applied onto an internal surface of the body cavity. Medical procedures or pleasurable activities related to the body cavity may then be performed which rely upon or are aided in part by the lubrication of the body cavity's internal surface.
Owner:GROWTH ARMOR LLC

Cervical HPV treatment suppository

The utility model discloses a cervical HPV (human papilloma virus) treatment suppository which comprises a supporting part, a second sleeve and an atomizing spray pipe, a first sleeve is arranged on the supporting part, and the first sleeve penetrates through the supporting part and extends outwards to be connected with a limiting head arranged at the end of the supporting part; an operating handle is arranged at the end part of the second sleeve, the operating handle is arranged in the limiting head in a penetrating manner, the second sleeve is arranged in the first sleeve in a penetrating manner, and an activated carbon fiber coating layer for adhering secretions is arranged on the part, extending outwards from the inside of the first sleeve, of the second sleeve; the atomizing spray pipe is arranged in the second sleeve in a penetrating mode, one end of the atomizing spray pipe is provided with an oval atomizing spray head, the other end of the atomizing spray pipe is provided with a connector used for being connected into an atomizing pipe of an atomizing machine, and the connector is arranged in the operating handle in a penetrating mode. A combined design structure is adopted, the affected part of a patient can be cleaned, atomized and sprayed, atomized medicine is fully exerted to directly reach the affected part, and the treatment effect is improved.
Owner:HENAN AFFILIATED UNIVERSITY DOCTORS GROUP CO LTD

A composition for human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) and its preparation method.

This invention discloses a composition and its preparation method for treating human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN), belonging to the field of traditional Chinese medicine technology. The formula consists of 6-15 parts of American cockroach, 5-11 parts of hawthorn, 5-11 parts of chicory, 3-9 parts of *Scutellaria baicalensis*, 8-20 parts of *Sophora flavescens*, and 6-15 parts of *Cnidium monnieri*, and also contains 0.01-1 parts by weight of toad venom. The dosage form is one or more of the following: external gel, rinse, foam, suppository, and film preparation. It has high safety and is suitable for HPV infection and CIN changes, solving the problem of poor efficacy in existing treatments.
Owner:ZHONGRUNDA (CHANGZHOU) BIOMEDICAL TECHNOLOGY CO LTD

Tissue plasminogen activator coated catheters with controlled hydrogel elution

The invention relates to an antithrombotic catheter. The antithrombotic catheter comprises a hydrogel coating containing a thrombolytic agent. The thrombolytic agent may be a lyophilized tissue plasminogen activator. The catheter has an inner lumen surface and an outer lumen surface, and a hydrogel coating is disposed on the inner lumen surface and / or the outer lumen surface. The hydrogel coating may have a thickness in the range of about 50 nm to about 150 nm. The hydrogel coating may contain from about 0.1 wt% to about 1 wt% of a tissue plasminogen activator. The hydrogel coating may be made from a synthetic hydrogel or a natural hydrogel. Presently preferred synthetic hydrogels include polyacrylamide based hydrogels. Presently preferred natural hydrogels include hyaluronic acid based hydrogels. The hydrogel coating reacts in the presence of a physiological liquid to absorb water and elute the solvating suppository. The hydrogel controls elution of the thrombolytic agent. Examples of physiological fluids include interstitial fluids and blood.
Owner:BECTON DICKINSON & CO

Emulsion type suppository practical for vaginal administration

The invention discloses an emulsion type suppository practical for vaginal administration, and relates to the technical field of pharmaceutical preparations, the suppository is a solid at room temperature, and can be converted into a cream type preparation in situ under vaginal temperature and wetting conditions; the suppository is composed of active and pharmaceutically acceptable auxiliary materials, the auxiliary materials comprise structural lipid, an emulsifier, a gel matrix and a pH regulator, and a suppository body is softened at body temperature and mixed with body fluid to form a cream mixture easy to coat on the mucous membrane surface in situ. The transformation process avoids greasy feeling and local discomfort possibly brought by a traditional greasy suppository, and also eliminates the trouble that the prefabricated cream needs to be matched with a special administration device, so that the local medication experience of a patient is improved while the administration convenience is ensured. Besides, through reasonable selection of auxiliary materials, the cream formed through conversion can provide proper adhesion, and the retention time of the medicine at the action part can be prolonged.
Owner:SHIJIAZHUANG LUANRUI NEW ENERGY TECHNOLOGY CO LTD

Method for increasing early pregnancy rate of sheep

The invention provides a method for increasing the early pregnancy rate of sheep, and belongs to the field of livestock breeding. According to the invention, beta-glucan is adopted to feed sheep. The specific steps of feeding sheep with beta-glucan are as follows: step 1, preparing a concentrated feed premix for ewes, mixing beta-glucan with the premix, the weight of beta-glucan being 0.2% of the weight of the premix; 2, feeding time: starting to add 0.2% of beta-glucan into the concentrated feed premix of the ewes on the ninth day after the ewes are subjected to estrus identification and the rams are bred, and feeding for 3 weeks, namely on the thirtieth day after breeding; on the 45th day after mating of the ewes, pregnancy diagnosis is carried out through B-mode ultrasound. The feed additive can improve the early pregnancy rate of the sheep, is low in cost, does not damage the vagina of the ewe, and does not cause hormone residue in the body of the ewe; at the same time, the embedded vagina suppository does not meet the requirement of animal welfare, and the used suppository is easy to cause environmental pollution. And the operation is simple.
Owner:HEBEI UNIV OF ENG

Glycerol enema capable of being administrated for multiple times

ActiveCN223366071UMedical devicesSuppositoryMultiple administration
The utility model relates to the technical field of glycerine enema, in particular to glycerine enema capable of being dosed repeatedly, which comprises a liquid storage ball, an anti-leakage mechanism arranged above the liquid storage ball and a complete extrusion mechanism arranged above the liquid storage ball, the anti-leakage mechanism comprises a connecting pipe, the connecting pipe is fixedly connected to the upper end of the liquid storage ball, and the connecting pipe is connected with the complete extrusion mechanism. The connecting pipe is rotationally arranged in the rotating sleeve, a first through groove is formed in the connecting pipe, a connecting ring is fixedly connected to the upper end of the rotating sleeve, a fixing plate is fixedly connected to the inner wall of the connecting ring, a second through groove is formed in the fixing plate, and the area of the second through groove is the same as that of the first through groove; the upper end of the connecting ring is fixedly connected with an extrusion pipe, and a lengthening pipe is installed at the upper end of the extrusion pipe. According to the enema capable of dosing for multiple times, the enema can be conveniently dosed, the dosed enema can be sealed subsequently, pollution and waste caused by automatic extrusion of leaked enema are avoided, and the practicability and the closeness of the enema are improved.
Owner:HENAN LINGYOU PHARMA

Vagina medicine applying device

ActiveCN223311520UMedical devicesPharmacy medicineManual medicine
The utility model relates to the technical field of vagina medicine applying devices, in particular to a vagina medicine applying device which comprises a shell and a medicine applying structure, connecting grooves are formed in the two sides of one end of the shell respectively, a guide groove is formed in the middle of the other end of the shell, and the connecting grooves and the guide groove are used for being connected with the medicine applying structure. The push rod is pushed to drive the sleeve rod to move synchronously, the sleeve rod drives the shell covers to rotate through the connecting rod, the shell covers on the two sides are unfolded along the shell to open the vagina, suppository medicine can better enter a focus conveniently, the sleeve rod drives the bowl-shaped block to be pushed out while the shell covers are unfolded, and the suppository medicine is pushed to the position close to the focus. At the moment, the sleeve rod drives the round block to be attached to the sleeve block, the person continues to push the push rod, the push rod drives the spring to be compressed through the connecting block, the push rod drives the push block to push the suppository medicine out of the bowl-shaped block, and the suppository medicine in the bowl-shaped block is further pushed to the focus. The problem that manual medicine applying is prone to being far away from the focus position, and the medicine applying effect is affected is solved.
Owner:FIRST HOSPITAL OF QINHUANGDAO

A suppository for treating bovine and ovine endometritis, a preparation method and application thereof

This invention discloses a suppository for treating endometritis in cattle and sheep, its preparation method, and its application, belonging to the field of veterinary drug preparation technology. The suppository uses Salvia miltiorrhiza, Coptis chinensis, Forsythia suspensa, Carthamus tinctorius, Borneol, and Astragalus membranaceus as active ingredients. Coptis chinensis and Forsythia suspensa clear damp-heat, while Salvia miltiorrhiza and Carthamus tinctorius unblock stagnation. Astragalus membranaceus replenishes postpartum qi deficiency, promotes blood circulation, enhances blood circulation, strengthens the body's resistance to pathogens, prevents inflammation recurrence, harmonizes the cold properties of other herbs, and reduces side effects. Borneol, with its pungent and penetrating properties, guides the medicine directly to the lesion, promotes mucosal repair, increases mucosal permeability, relieves pain and itching, and synergistically provides anti-inflammatory and analgesic effects, improving the user experience. It is suitable for local suppository administration, aligning with the principles of traditional Chinese veterinary medicine for endometritis, simultaneously exerting the effects of clearing heat and dampness, promoting blood circulation and removing blood stasis, and tonifying qi and strengthening the body, addressing both the symptoms and the root cause. By adding a matrix and excipients and combining vaginal administration to treat endometritis in cattle and sheep, the local drug concentration is concentrated for rapid onset of action, achieving a balance between effectiveness, convenience, and safety.
Owner:NORTHWEST A & F UNIV +1

Polyglutamic acid compositions and methods of use

PendingCN122138818AOrganic active ingredientsCosmetic preparationsVaginal drynessSuppository
This document discloses compositions comprising one or more polyglutamic acid compounds. These compositions are used to treat, improve, prevent, or alleviate symptoms of vaginal dryness and menopausal symptoms. This document also describes compositions for treating, improving, preventing, or alleviating other dry skin symptoms on the body, extremities, hands, feet, neck, or face in subjects of all ages and sexes. This document also describes topical and suppository formulations of the compositions.
Owner:博纳菲德健康有限公司

Medical kit (hemorrhoid suppository)

ActiveCN309657856SSuppositoryBiomedical engineering
1. The name of the design product: medicine box (hemorrhoid suppository). 2. The use of the design product: the design product is used for packaging hemorrhoid suppository medicine. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: unfolded state diagram.
Owner:ANQING YUNSONG TRADING CO LTD

Double-layer anus suppository for intestinal flora transplantation and preparation method of double-layer anus suppository

The invention provides a double-layer anus suppository for intestinal flora transplantation and a preparation method thereof, and relates to the technical field of biological medicine, the double-layer anus suppository comprises an outer layer and an inner layer, the outer layer is prepared from the following components in percentage by weight: 88-94% of low-melting-point semi-synthetic fatty glyceride, 0.5-3% of temperature-sensitive gel, 3-8% of polyethylene glycol, 1-4% of lubricating additive and 0.5-2% of surfactant, and the inner layer is prepared from the following components in percentage by weight; the inner layer is prepared from the following components in percentage by weight: 80-90% of high-melting-point semi-synthetic fatty glyceride, 1-25% of intestinal flora freeze-dried powder, 2-6% of a freeze-drying protective agent, 5-12% of polyethylene glycol and 0.5-3% of an emulsifier; by the adoption of the double-layer design, after entering the rectum, the double-layer enteric-coated suppository can be rapidly softened and responded, discomfort is effectively reduced, displacement is rapidly started by means of intestinal tract lubrication, meanwhile, the rectum environment is isolated in the initial stage, the inner layer core is protected, and it is ensured that active ingredients are released in a large number after being accurately delivered.
Owner:BIOTEC (SHENYANG) BIOMEDICAL GRP CO LTD

A rectal delivery device for colorectal

ActiveCN224686157UPharmacy medicineSuppository
The utility model provides a kind of for colorectal anus medicine feeder, belong to medical appliance technical field, including medicine feeder, the end portion of medicine feeder is connected with connecting cap by screw thread, the outer end of connecting cap is fixedly connected with medicine tube, a group of medicine holes is evenly set on the medicine tube, the outer end of medicine tube is connected with connecting head by internal thread, the outer end of connecting head is fixedly connected with connecting plate, the connecting plate is fixedly connected with plug elastic clamp, the medicine feeder is equipped with moving block, the outer circumferential side wall of moving block is fixedly connected with piston ring.The utility model is equipped with connecting cap, medicine tube, medicine hole, connecting head, connecting plate, plug elastic clamp and push medicine mechanism, realizes both can deliver hydraulic medicine to the patient's affected area and can deliver suppository medicine to the patient's affected area, significantly improve the flexibility of medicine feeder, can deliver suppository medicine to position, guarantee the full play of drug efficacy, solve the problem of inconvenient delivery suppository medicine in prior art.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY

Composition, kit and application thereof, and application of microorganisms

The invention discloses a composition which comprises a lysis buffer solution, an ATL buffer solution and protease K, a kit containing the composition, and application of vaginal microorganisms in construction of a diagnostic model of dinoprostone thrombosis sensitivity. Therefore, the prediction model of the dinoprostone labor induction sensitivity can be constructed based on vaginal microorganisms, so that decisions and help are provided for clinicians to judge the dinoprostone labor induction sensitivity of pregnant women, and the method has important significance in reducing pain of patients.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Compound infantile antipyretic double-layer suppository and manufacturing method thereof

PendingCN121370976AOrganic active ingredientsAntipyreticContinuous feverSymptom improvement
The invention discloses a compound infantile antipyretic double-layer suppository and a preparation method thereof, and relates to the technical field of pharmaceutical preparations, the compound infantile antipyretic double-layer suppository is composed of a quick release layer and a slow release layer, the quick release layer comprises 150-180g / 1000 paracetamol, 4-6g / 1000 artificial bezoar, 10-20g / 1000 sustained release layer, 10-20g / 1000 sustained release layer, 10-20g / 1000 sustained release layer and 10-20g / 1000 sustained release layer. The sustained release layer comprises 40-60g / 1000 pieces of rhizoma et radix baphicacanthis cusiae extract powder and 40-60g / 1000 pieces of acetaminophen, biphase drug release is achieved through the hydrophilic and hydrophobic difference of a bilayer matrix, the onset time can be shortened, the continuous fever abatement time can be prolonged, and the symptom improvement rate of a patient is greatly increased.
Owner:JIANGXI JIUHUA PHARMA

Antibacterial peptide Ly (PEG)-1 for preventing and treating vaginitis and product containing Ly (PEG)-1

The invention provides a novel application of an antibacterial peptide Ly (PEG)-1 reported at an earlier stage in vaginitis, belongs to the technical field of biomedical polypeptides, and particularly relates to preparation of the antibacterial peptide Ly (PEG)-1, an effect of the antibacterial peptide Ly (PEG)-1 on main vaginal pathogenic bacteria and symbiotic bacteria and an application of the antibacterial peptide Ly (PEG)-1 in prevention or treatment of bacterial vaginitis. The antibacterial peptide Ly (PEG)-1 provided by the invention is short in sequence, low in production cost, capable of strongly inhibiting main pathogenic bacteria of vagina, small in influence on main normal bacteria of the main pathogenic bacteria, capable of effectively treating vagina inflammation and maintaining the steady state of vaginal flora, high in stability and good in antibacterial effect. Vagina inflammatory diseases caused by infection of various pathogenic bacteria can be prevented and treated through various administration modes such as spraying, instillation, suppositories and effervescent tablets or systemic administration modes such as intraperitoneal injection and the like.
Owner:HUNAN NORMAL UNIVERSITY

Packaging box (6 tablets of Qianlie Biertong suppository)

ActiveCN309497013SSuppositorySurgery
1. The name of the product under this design: packaging box (6 tablets of Qianlie Biertong suppositories). 2. Purpose of this design product: used for packaging prostate-blocking suppositories. 3. The key design points of this product are the combination of shape, pattern and color. 4. The picture or photo that best illustrates the key points of the design: main view. 5. The design for which protection is sought includes color.
Owner:HEILONGJIANG JIREN PHARMACEUTICAL CO LTD

Packaging box (hemorrhoid suppository)

ActiveCN309898211SSuppositoryMedicinal chemistry
1. Name of the designed product: packing box (hemorrhoid suppository). 2. Use of the designed product: for product packing. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: front view.
Owner:HUNAN ZHUANGYUAN PHARM CO LTD

A probiotic composition for preventing and / or treating vaginal infections and diseases associated therewith and uses thereof

PendingCN122326423Agood effectReduced pathogen loadDiseaseLactobacillus fermentum
This invention provides a probiotic composition for the prevention and / or treatment of vaginal infections and related diseases, and its use therein. The probiotic composition comprises *Lactobacillus plantarum* and *Lactobacillus fermentum*, wherein the gene sequence of the molecular marker of *Lactobacillus plantarum* has the nucleotide sequence shown in SEQ ID NO: 1, or the nucleotide sequence thereof is shown in SEQ ID NO: 1; and the gene sequence of the molecular marker of *Lactobacillus fermentum* has the nucleotide sequence shown in SEQ ID NO: 2, or the nucleotide sequence thereof is shown in SEQ ID NO: 2. The probiotic composition of this invention achieves better efficacy in treating vaginal infections, especially vulvovaginal candidiasis, compared to single strains therein and existing positive control drugs such as metronidazole suppositories.
Owner:HANGZHOU GRAND BIOLOGIC PHARMA INC

Collagen-based antibacterial peptide and preparation method thereof

The invention belongs to the technical field of polypeptide preparation, and provides collagen-based antibacterial peptide and a preparation method thereof. Connecting carboxyl of the collagen peptide with amino acid, dipeptide or tripeptide; the amino acid, the dipeptide or the tripeptide is composed of lysine and arginine. The antibacterial peptide can be used as an effective component of an antibacterial drug and can be prepared into an external application patch, a suppository, a surgical implant material and the like for preventing bacterial and fungal infection. The antibacterial peptide can also be used as a feed additive or a veterinary drug to be applied to animals. The raw materials are wide in source, the synthesis method is simple, and the cost is low; the prepared antibacterial peptide is good in salt tolerance, has an antibacterial effect under a wide pH range, and is good in biological safety; the antibacterial peptide has a good inhibition effect on gram-negative and gram-positive bacteria, especially has good biological activity on common vaginal malignant bacteria, and has a wide application prospect.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES)