A miniaturized obstruction treatment device, e.g., a
brush, particularly adapted for medical use formed at the distal end of an elongated
brush drive shaft having a hollow lumen formed therein for introduction over a guidewire. The
brush drive shaft is enclosed in the lumen of an brush delivery
catheter, and the brush bristles of the distal brush are adapted to be garaged in a distal end section of the brush delivery
catheter lumen. A Y-connector and an brush sub-
assembly connector are attached to the proximal end of the brush delivery
catheter and form an brush sub-
assembly with the brush
drive shaft and brush. The Y-connector allows infusion of thrombolytic agents into the brush delivery catheter lumen for emission at the distal end opening thereof adjacent the brush. In use, the brush sub-
assembly connector connects the brush sub-assembly with a
drive motor unit connector of a
drive motor unit. The
drive motor unit receives the proximal end of the drive shaft and rotates it to rotate the brush bristles. The brush and brush drive shaft distal section are automatically extended out of the catheter lumen distal end opening when the sub-assembly connector and the drive
motor unit connector positively lock together. Simultaneously, a drive hub of the brush drive shaft locks into a drive chuck of a drive
motor unit to enable rotation of the drive shaft, and the proximal drive shaft end is seated in a dynamic seal that inhibits infiltration of blood and
thrombolytic agent into the drive motor housing.